The effects of whole-body vibration training and vitamin D supplementation on muscle strength, muscle mass, and bone density in institutionalized elderly women: A 6-month randomized, controlled trial
Open accessAbstract
Sarcopenia and osteoporosis represent a growing public health problem. We studied the potential benefit of whole-body vibration (WBV) training given a conventional or a high dose of daily vitamin D supplementation in improving strength, muscle mass, and bone density in postmenopausal women. In a 2 × 2 factorial-design trial, 113 institutionalized elderly females aged over 70 years (mean age 79.6 years) were randomly assigned either to a WBV or a no-training group, receiving either a conventional dose (880 IU/day) or a high dose (1600 IU/day) of vitamin D3. The primary aim was to determine the effects of 6 months of WBV and/or vitamin D supplementation on isometric and dynamic strength, leg muscle mass, and hip bone mineral density (BMD). Additionally, the increase in 25-hydroxyvitamin D [25(OH)D] levels between conventional and high-dose supplementation was compared. After 6 months of treatment, dynamic muscle strength, hip BMD, and vitamin D serum levels improved significantly in all groups, whereas isometric strength and muscle mass did not change. When compared with no training, the WBV program did not result in additional improvements. When compared with 880 IU, a high dose of 1600 IU of vitamin D did result in higher serum vitamin D levels but did not result in additional improvements. In institutionalized women older than 70 years, the WBV training protocol tested is not more efficient in enhancing muscle mass, strength, and hip BMD compared with vitamin D supplementation. A higher dose of 1600 IU of vitamin D does not provide additional musculoskeletal benefit in this population compared with conventional doses. © 2011 American Society for Bone and Mineral Research.
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The summative effects of combining whole-body vibration therapy with resistance exercises or with vitamin D are mixed.
“Summative effects of the combination of whole body vibration therapy and resistance exercises374–377 or of whole-body vibration therapy and vitamin D367 are mixed.”
From Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies (2018) · cites this paper as [367]
The Interaction effects section (page unavailable) reports no evidence of an interactive effect between whole-body vibration and vitamin D for any outcome. This supports a lack of additional benefit from the combination in this trial, but the paper does not itself report mixed effects of that combination. The resistance-exercise clause is attributed to other citations, not this source. (LLM, conf=0.78)
Experimental — accuracy not yet measuredWhole-body vibration therapy transmits mechanical stimuli through the body to activate primary endings of muscle spindles, leading to neuromuscular activation.
“Whole-body vibration therapy uses the transmission of mechanical stimuli through the person’s body365,366 to activate the primary ends of muscle spindles, which leads to neuromuscular activation367–369.”
From Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies (2018) · cites this paper as [367]
Whole-body electromyostimulation (WB-EMS) has emerged as a useful treatment for sarcopenia and sarcopenic obesity, showing promising effects due to its similarities to resistance training.
“Furthermore, whole-body electromyostimulation (WB-EMS) has emerged in research as a useful treatment for sarcopenia [18] and sarcopenic obesity, showing promising effects due to its similarities to resistance training [5, 19, 20].”
From Effects of nutrition and exercise interventions on persons with sarcopenic obesity: an umbrella review of meta-analyses of randomised controlled trials (2023) · cites this paper as [20]
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- Authors
- Verschueren, S. M., Bogaerts, A., Delecluse, C., Claessens, A. L., Haentjens, P., Vanderschueren, D., & Boonen, S.
- Affiliations
- KU Leuven (BE)
- Vrije Universiteit Brussel (BE)
- Universitair Ziekenhuis Leuven (BE)
- Corresponding author
- Verschueren, Sabine MP
- Venue
- Journal of Bone and Mineral Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2010-12-22
- Volume
- 26
- Issue
- 1
- Pages
- 42-49
- ISSN
- 0884-0431 (ISSN-L)
- 1523-4681
- OpenAlex
- W2014087172
- Cited by
- 148
- References
- 44
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 5 · 2023: 10 · 2022: 12 · 2021: 3 · 2020: 13 · 2019: 12 · 2018: 2 · 2017: 8 · 2016: 10 · 2015: 18 · 2014: 15 · 2013: 13 · 2012: 13
- FWCI
- 10.85
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- Journal of Bone and Mineral Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Fonds Wetenschappelijk Onderzoek
- Universität Zürich
- Vlaamse regering
- Topics
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Effects of Vibration on Health
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Health Sciences › Medicine › Pathology and Forensic Medicine › Vitamin D Research Studies
- Keywords
- whole-body vibration training, vitamin D supplementation, high-dose vitamin D, sarcopenia, osteoporosis, postmenopausal women, institutionalized elderly, muscle strength, muscle mass, hip bone density, 25-hydroxyvitamin D, isometric strength, dynamic strength
- MeSH terms
- Aged, Aged, 80 and over, Female, Humans, Institutionalization, Organ Size, Patient Compliance, Vibration, Vitamin D, Bone Density, Treatment Outcome, Dietary Supplements, Muscle Strength
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