The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Muscle strength, physical fitness, and weight but not age predict femoral neck bone mass
Abstract
Hip fractures are the most serious complication of osteoporosis. Although low proximal femoral bone mineral density (BMD) does not cause hip fractures directly, it is clearly a prerequisite for the increased risk associated with aging. To investigate the mechanism of the age-related decline in proximal femoral bone mineral density, we have examined the relative importance of muscle strength, physical fitness, and body mass index (BMI) in addition to age in the determination of proximal femoral BMD in 73 healthy female volunteers age 20–75 years. Muscle strength was an independent predictor of BMD at all three sites in the proximal femur as well as in the lumbar spine and forearm; proximal femur BMD was also predicted by physical fitness. BMI was a positive predictor of bone mass at all sites. In the proximal femur, age was not an independent predictor of BMD at any site. In postmenopausal women muscle strength was a significant predictor of bone mass in the femur and forearm, but not in the spine. However, BMI remained predictive of bone mineral at all sites. Muscle strength, physical fitness, and weight appear to exert independent effects upon bone mass. Age effects may be mediated indirectly through associated changes in these factors. The integrated physical load on the skeleton may be a final common pathway.
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Cites
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Hip Fracture and the Use of Estrogens in Postmenopausal Women
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Hip Fracture and the Use of Estrogens in Postmenopausal Women: The Framingham Study
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Physical Exercise as Prophylaxis against Involutional Vertebral Bone Loss: A Controlled Trial
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Calcium Homeostasis in Immobilization: An Example of Resorptive Hypercalciuria
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Prevention of Involutional Bone Loss by Exercise
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Cited by
Prediction of bone density from vitamin D receptor alleles
Morrison, N. A., Qi, J. C., Tokita, A., Kelly, P. J., Crofts, L., Nguyen, T. V., Sambrook, P. N., & Eisman, J. A. (1994) · Nature · doi:10.1038/367284a0 · Cited by 1,919
Self-citationGarvey, W. T., Mechanick, J. I., Brett, E. M., Garber, A. J., Hurley, D. L., Jastreboff, A. M., Nadolsky, K., Pessah-Pollack, R., & Plodkowski, R. (2016) · Endocrine Practice · doi:10.4158/ep161365.gl · Cited by 1,914
Effects of weight and body mass index on bone mineral density in men and women: The framingham study
Felson, D. T., Zhang, Y., Hannan, M. T., & Anderson, J. J. (1993) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650080507 · Cited by 987
Villareal, D. T., Apovian, C. M., Kushner, R. F., & Klein, S. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.5.923 · Cited by 880
Villareal, D. T., Apovian, C. M., Kushner, R. F., & Klein, S. (2005) · Obesity Research · doi:10.1038/oby.2005.228 · Cited by 579
Metadata
- Authors
- Pocock, N., Dr. Eisman, J., Gwinn, T., Sambrook, P., Kelly, P., Freund, J., & Yeates, M.
- Venue
- Journal of Bone and Mineral Research
- Publisher
- Oxford University Press (OUP)
- Published
- 1989-06-01
- Volume
- 4
- Issue
- 3
- Pages
- 441-448
- ISSN
- 0884-0431 (ISSN-L)
- 1523-4681
- OpenAlex
- W2072283948
- Cited by
- 313
- References
- 33
- FWCI
- 14.47
- Type
- journal article
- Language
- en
- Open access
- closed
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- Pocock, N., Dr. Eisman, J., Gwinn, T., Sambrook, P., Kelly, P., Freund, J., & Yeates, M. (1989). Muscle strength, physical fitness, and weight but not age predict femoral neck bone mass. Journal of Bone and Mineral Research. https://doi.org/10.1002/jbmr.5650040320
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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