Pharmacotherapy of adult ADHD
Abstract
Although attention deficit hyperactivity disorder (ADHD) has been officially recognized as persisting into adulthood for more than 25 years, only recently has the condition been studied in adults. There is great syndromatic continuity between childhood and adult ADHD, and thus much of the medication management of adults with ADHD can be based on the experience gained from treating children and adolescents. Stimulant medications remain the treatment of choice and are generally as effective in adults as they are in children. Several extended-release delivery systems that improve convenience and compliance have become available. Several second-line medications are also reviewed. The medications must be fine-tuned to the needs of the individual patient in regard to the dose and timing of dose that achieve optimal therapeutic benefit. Medication adjustment must be done by trial and error because no parameter yet identified predicts the molecule or dose that will provide optimal performance.
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“While national and international guidelines consistently advocate for the treatment of adult ADHD to be multidisciplinary (e.g., Kooij et al. (2019), in practice, pharmacotherapy may be the treatment of choice to aid attention and concentration (Dodson, 2005).”
- Authors
- Dodson, W. W.
- Corresponding author
- Dodson, William W.
- Venue
- Journal of Clinical Psychology
- Publisher
- Wiley
- Published
- 2005-02-18
- Volume
- 61
- Issue
- 5
- Pages
- 589-606
- ISSN
- 0021-9762 (ISSN-L)
- 1097-4679
- OpenAlex
- W2126663968
- Cited by
- 88
- References
- 5
- Citations by year
- 2025: 3 · 2023: 2 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 2 · 2017: 2 · 2016: 6 · 2015: 1 · 2014: 5 · 2013: 5 · 2012: 8
- FWCI
- 5.01
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical Psychology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neuroethics, Human Enhancement, Biomedical Innovations
- Health Sciences › Medicine › Pharmacology › Pharmacology and Obesity Treatment
- Keywords
- adult ADHD, pharmacotherapy, stimulant medication, sustained-release formulation, dose titration, medication adherence, treatment response variability
- MeSH terms
- Atomoxetine Hydrochloride, Adolescent, Adult, Age Factors, Amphetamine, Central Nervous System Stimulants, Antidepressive Agents, Attention Deficit Disorder with Hyperactivity, Behavior Therapy, Child, Combined Modality Therapy, Delayed-Action Preparations, Dose-Response Relationship, Drug, Drug Administration Schedule, Female, Humans, Male, Methylphenidate, Propylamines, Treatment Outcome
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