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Formation and properties of thin‐walled phospholipid vesicles

Reeves, John P., Dowben, Robert M.·1969·Journal of Cellular Physiology

Abstract

Large numbers of thin‐walled vesicles, 0.5 to 10 μ in diameter, can be formed by permitting a thinly spread layer of hydrated phospholipids to swell slowly in distilled water or an aqueous solution of nonelectrolytes. Electron micrographs and phospholipid analyses indicate that the walls consist of a single or a few bilayers. The vesicles can be centrifuged and resuspended in another medium, making them a useful system for studying permeability. The osmolarity of the solution in the interior of the vesicles can be estimated by immersion refractometry. The osmolarity of the internal aqueous phase is linearly related to the osmolarity of the external medium.

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Crossref · 10.1002/jcp.1040730108

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Metadata

Authors
Reeves, J. P., & Dowben, R. M.
Venue
Journal of Cellular Physiology
Publisher
Wiley
Published
1969-02
Volume
73
Issue
1
Pages
49-60
ISSN
  • 0021-9541 (ISSN-L)
  • 1097-4652
OpenAlex
W2120644189
Cited by
656
References
1
FWCI
1.91
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Formation and properties of thin‐walled phospholipid vesicles. https://app.cochat.ai/papers/10.1002/jcp.1040730108
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Reeves, J. P., & Dowben, R. M. (1969). Formation and properties of thin‐walled phospholipid vesicles. Journal of Cellular Physiology. https://doi.org/10.1002/jcp.1040730108

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.