The epidermal growth factor receptor ligands at a glance

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2. Regulation of Gastrointestinal Mucosal Growth
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3. Epidermal growth factor receptor immunohistochemistry: new opportunities in metastatic colorectal cancer
   Ryan A. Hutchinson, Richard Adams, Darragh G. McArt, Manuel Salto‐Tellez, Bharat Jasani, Peter W. Hamilton · 2015 · Journal of Translational Medicine
4. Constitutive Activation of Epidermal Growth Factor Receptor Promotes Tumorigenesis of Cr(VI)-transformed Cells through Decreased Reactive Oxygen Species and Apoptosis Resistance Development
   Donghern Kim, Jin Dai, Leonard Nsoyori Yenwongfai, Hua Yao, Young‐Ok Son, Lei Wang, Poyil Pratheeshkumar, Kazuya Kondo, Xianglin Shi, Zhuo Zhang · 2014 · Journal of Biological Chemistry
5. Heparin-binding EGF-like growth factor (HB-EGF) stimulates the proliferation of Müller glia-derived progenitor cells in avian and murine retinas
   Levi J. Todd, Leo I. Volkov, Christopher Paul Zelinka, Natalie A. Squires, Andy J. Fischer · 2015 · Molecular and Cellular Neuroscience
6. TRPV1 inhibition overcomes cisplatin resistance by blocking autophagy-mediated hyperactivation of EGFR signaling pathway
   Se Jin Oh, Ji Yeon Lim, Min Kyu Son, Jun Hyeok Ahn, Kwon‐Ho Song, Hyo‐Jung Lee, Suyeon Kim, Eunho Cho, Joon‐Yong Chung, Hanbyoul Cho et al. · 2023 · Nature Communications
7. Calmodulin‐mediated regulation of the epidermal growth factor receptor
   Pablo Sánchez‐González, Karim Jellali, Antonio Villalobo · 2009 · FEBS Journal
8. Disturbed Cartilage and Joint Homeostasis Resulting From a Loss of Mitogen‐Inducible Gene 6 in a Mouse Model of Joint Dysfunction
   Michael Andrew Pest, Bailey A. Russell, Yu‐Wen Zhang, Jae‐Wook Jeong, Frank Beier · 2014 · Arthritis & Rheumatology
9. Serum-Dependent Selective Expression of EhTMKB1-9, a Member of Entamoeba histolytica B1 Family of Transmembrane Kinases
   Shiteshu Shrimal, Sudha Bhattacharya, Alok Bhattacharya · 2010 · PLoS Pathogens
10. NRG1-Fc improves metabolic health via dual hepatic and central action.
    Peng Zhang, Henry Kuang, Yanlin He, Sharon O. Idiga, Si-Ming Li, Zhimin Chen, Zhao Yang, Xing Cai, Ke-Zhong Zhang, Matthew J. Potthoff et al. · 2018 · JCI Insight
11. Titanium dioxide nanoparticles induce apoptosis by interfering with EGFR signaling in human breast cancer cells
    Hyungjoo Kim, Donghwan Jeon, Sunhwa Oh, KeeSoo Nam, Seogho Son, Myung Chan Gye, Incheol Shin · 2019 · Environmental Research
12. Recent advances on the roles of epidermal growth factor receptor in psoriasis.
    Sijia Wang, Zhuoli Zhang, Han Peng, Kang Zeng · 2019 · Europe PMC (PubMed Central)
13. Regulation of Energy Metabolism by Receptor Tyrosine Kinase Ligands
    Meng Zhao, Yunshin Jung, Zewen Jiang, Katrin J. Svensson · 2020 · Frontiers in Physiology
14. Cellular crosstalk during liver regeneration: unity in diversity
    Wenzhi Shu, Mengfan Yang, Jiayin Yang, Shengda Lin, Xuyong Wei, Xiao Xu · 2022 · Cell Communication and Signaling
15. LC3B upregulation by NANOG promotes immune resistance and stem-like property through hyperactivation of EGFR signaling in immune-refractory tumor cells
    Suyeon Kim, Hanbyoul Cho, Soon-Oh Hong, Se Jin Oh, Hyo-Jung Lee, Eunho Cho, Seon Rang Woo, Joon Seon Song, Joon‐Yong Chung, Sung Wook Son et al. · 2020 · Autophagy
16. Hepatocellular Carcinoma: Old and Emerging Therapeutic Targets
    Greta Pessino, Claudia Scotti, Maristella Maggi · 2024 · Cancers
17. Tenascin-C is expressed by human glioma in vivo and shows a strong association with tumor blood vessels
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18. Dynamic conformational transitions of the EGF receptor in living mammalian cells determined by FRET and fluorescence lifetime imaging microscopy
    Iwona Ziomkiewicz, Anastasia Loman, Reinhard Klement, Cornelia Fritsch, Andrey S. Klymchenko, Gertrude Bunt, Thomas M. Jovin, Donna J. Arndt‐Jovin · 2013 · Cytometry Part A
19. Hormesis: wound healing and fibroblasts
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20. Cyclosporin A and tacrolimus induce renal Erk1/2 pathway via ROS-induced and metalloproteinase-dependent EGF-receptor signaling
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21. CCN2 inhibits lung cancer metastasis through promoting DAPK-dependent anoikis and inducing EGFR degradation
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22. Regulation of EGFR signalling by palmitoylation and its role in tumorigenesis
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23. Injury prevents Ras mutant cell expansion in mosaic skin
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24. Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease
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25. Autocrine epiregulin activates EGFR pathway for lung metastasis via EMT in salivary adenoid cystic carcinoma
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26. Molecular Markers of Anticancer Drug Resistance in Head and Neck Squamous Cell Carcinoma: A Literature Review
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27. A novel mechanism for the anticancer activity of aspirin and salicylates
    Asma’u I.J. Bashir, Chandra S. Kankipati, Sarah Jones, Robert Newman, Stephen T. Safrany, Christopher John Perry, Iain D. Nicholl · 2019 · International Journal of Oncology
28. Betacellulin Overexpression in Mesenchymal Stem Cells Induces Insulin Secretion In Vitro and Ameliorates Streptozotocin-Induced Hyperglycemia in Rats
    Ana Helena da Rosa Paz, Gabrielle Dias Salton, Ana Ayala‐Lugo, Cristiano Gomes, Paula Barros Terraciano, Rosana Scalco, Claudia Cilene Fernandes Correia Laurino, Eduardo Pandolfi Passos, Marlon Roberto Schneider, Luíse Meurer et al. · 2010 · Stem Cells and Development
29. Role of Heparin-Binding Epidermal Growth Factor-Like Growth Factor in Oxidative Stress-Associated Metabolic Diseases
    Seonwook Kim, Venkateswaran Subramanian, Ahmed Abdel‐Latif, Sangderk Lee · 2020 · Metabolic Syndrome and Related Disorders
30. Epidermal Growth Factor Receptor: A Potential Therapeutic Target for Diabetic Kidney Disease
    Lili Sheng, George P Bayliss, Shougang Zhuang · 2021 · Frontiers in Pharmacology
31. Design, synthesis, and molecular docking studies of novel pomalidomide-based PROTACs as potential anti-cancer agents targeting EGFR WT and EGFR T790M
    Moustafa O. Aboelez, Amany Belal, Guangya Xiang, Xiang Ma · 2022 · Journal of Enzyme Inhibition and Medicinal Chemistry
32. Electro-Metabolic Coupling of Cumulus–Oocyte Complex
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33. Lineage-specific co-evolution of the Egf receptor/ligand signaling system
    Juliette Agnès Geneviève Claire Laisney, Ingo Braasch, Ronald B. Walter, Svenja Meierjohann, Manfred Schartl · 2010 · BMC Evolutionary Biology
34. The role of protein kinases as key drivers of metabolic dysfunction-associated fatty liver disease progression: New insights and future directions
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35. Inhibition of epidermal growth factor receptor signaling prohibits metastasis of gastric cancer via downregulation of MMP7 and MMP13
    Yinghai Ye, Xiaocong Zhou, Xiaoyang Li, Yinhe Tang, Yusheng Sun, Jun Fang · 2014 · Tumor Biology · Retracted
36. Transcriptome analysis of the spalax hypoxia survival response includes suppression of apoptosis and tight control of angiogenesis
    Assaf Malik, Abraham B. Korol, Mathias Weber, Thomas Hankeln, Aaron Avivi, Mark Band · 2012 · BMC Genomics
37. Proliferative signaling by ERBB proteins and RAF/MEK/ERK effectors in polycystic kidney disease
    Mitchell I. Parker, Anna S. Nikonova, Danlin Sun, Erica A. Golemis · 2019 · Cellular Signalling
38. Loss of Amphiregulin drives inflammation and endothelial apoptosis in pulmonary hypertension
    Jonathan Florentin, Jingsi Zhao, Yi‐Yin Tai, Wei Sun, Lee L Ohayon, Scott O'Neil, Anagha Arunkumar, Xinyi Zhang, Jianhui Zhu, Yassmin Al Aaraj et al. · 2022 · Life Science Alliance
39. Epidermal growth factor receptor in corneal damage: update and new insights from recent reports
    Elena Bonafonte-Marquez, D. De Ortueta, Sergio Bonafonte-Royo, Pedro Antonio Martínez-Carpio · 2010 · Cutaneous and Ocular Toxicology
40. Diabetes and microvascular pathophysiology: role of epidermal growth factor receptor tyrosine kinase
    Khalid Matrougui · 2009 · Diabetes/Metabolism Research and Reviews
41. Inverse correlation between T hr‐669 and constitutive tyrosine phosphorylation in the asymmetric epidermal growth factor receptor dimer conformation
    Kanae Sato, Myoung‐Sook Shin, Ayaka Sakimura, Yue Zhou, Tomohiro Tanaka, Miho Kawanishi, Yuki Kawasaki, Satoru Yokoyama, Keiichi Koizumi, Ikuo Saiki et al. · 2013 · Cancer Science
42. Contact lenses as a drug delivery device for epidermal growth factor in the treatment of ocular wounds
    Clyde L Schultz, Douglas Walter Morck · 2010 · Clinical and Experimental Optometry
43. Regulation of Gastrointestinal Mucosal Growth
    Rao N. Jaladanki, Jian‐Ying Wang · 2011 · Colloquium Series on Integrated Systems Physiology From Molecule to Function
44. Pharmacogenomics and targeted therapy of cancer: Focusing on non-small cell lung cancer
    Seyyed Mortaza Haghgoo, Abdolamir Allameh, Esmaeil Mortaz, Johan Garssen, Gert Folkerts, Peter John Barnes, Ian Michael Adcock · 2015 · European Journal of Pharmacology
45. Animal models of schizophrenia for molecular and pharmacological intervention and potential candidate molecules
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46. The non-receptor tyrosine kinase Ack1 regulates activated EGFR fate by inducing trafficking to the p62/NBR1 pre-autophagosome
    Sylwia Jones, Debbie L. Cunningham, Joshua Zachary Rappoport, John K. Heath · 2014 · Journal of Cell Science
47. Kinase signaling pathways as targets for intervention in pancreatic cancer
    Meir Preis, Murray Korc · 2010 · Cancer Biology & Therapy
48. Epigen Transgenic Mice Develop Enlarged Sebaceous Glands
    Maik Dahlhoff, Anna‐Katharina Müller, Eckhard Wolf, Sabine Werner, Marlon Roberto Schneider · 2009 · Journal of Investigative Dermatology
49. ACE2-EGFR-MAPK signaling contributes to SARS-CoV-2 infection
    Melanie Engler, Dan Albers, Pascal von Maltitz, Rüdiger M. Groß, Jan Münch, Ion Cristian Cirstea · 2023 · Life Science Alliance
50. The Dyslexia-associated KIAA0319 Protein Undergoes Proteolytic Processing with γ-Secretase-independent Intramembrane Cleavage
    Antonio Velayos‐Baeza, Clotilde Lévecque, Kazuhiro Kobayashi, Zoe G. Holloway, Anthony P. Monaco · 2010 · Journal of Biological Chemistry
51. Heparin-binding epidermal growth factor (HB-EGF) drives EMT in patients with COPD: implications for disease pathogenesis and novel therapies
    Mathew Suji Eapen, Pawan Kumar Sharma, Isobel E. Thompson, Wenying Lu, Stephen Myers, Philip M. Hansbro, Sukhwinder Singh Sohal · 2018 · Laboratory Investigation
52. Integrated Ligand-Receptor Bioinformatic and In Vitro Functional Analysis Identifies Active TGFA/EGFR Signaling Loop in Papillary Thyroid Carcinomas
    Debora Degl’Innocenti, Chiara Alberti, Giancarlo Castellano, Angela Greco, Claudia Miranda, Marco Alessandro Pierotti, Ettore Cesare Seregni, Maria Grazia Borrello, Silvana Canevari, Antonella Tomassetti · 2010 · PLoS ONE
53. Inhibition of FoxO1 nuclear exclusion prevents metastasis of Glioblastoma
    Jin Chen, Qin Huang, Feng Wang · 2014 · Tumor Biology · Retracted
54. Mechanisms of inhibition of human benign prostatic hyperplasia in vitro by the luteinizing hormone‐releasing hormone antagonist cetrorelix
    Agnieszka Siejka, Andrew Victor Schally, Norman L. Block, Nektarios Barabutis · 2010 · British Journal of Urology
55. Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis
    Marina Badenes, Abdulbasit Amin, Ismael González‐García, Inês Félix, Emma Burbridge, Miguel A. S. Cavadas, Francisco José Ortega, Érika de Carvalho, Pedro Faísca, Stefania Carobbio et al. · 2019 · Molecular Metabolism
56. Chemopreventive effect of leflunomide against Ehrlich's solid tumor grown in mice: Effect on EGF and EGFR expression and tumor proliferation
    Hoda Ibrahim Bahr, Eman Ali Toraih, Eman Abdel-Momen Mohammed, Hala M.F. Mohammad, Eman Ali, Sawsan A. Zaitone · 2015 · Life Sciences
57. Structure and function of epigen, the last EGFR ligand
    Marlon Roberto Schneider, Yosef Yarden · 2013 · Seminars in Cell and Developmental Biology
58. Exosomes derived from oviduct cells mediate the EGFR/MAPK signaling pathway in cumulus cells
    Seok Hee Lee, Hyun Ju Oh, Min Jung Kim, Byeong Chun Lee · 2019 · Journal of Cellular Physiology
59. Matrix metalloproteinase-10 protects against acute kidney injury by augmenting epidermal growth factor receptor signaling
    Chengxiao Hu, Yangyang Zuo, Qian Ren, Xiaoli Sun, Shan Yu Zhou, Jinlin Liao, Xue Hong, Jinhua Miao, Lili Zhou, Youhua Liu · 2021 · Cell Death and Disease
60. Overexpression of Epigen during Embryonic Development Induces Reversible, Epidermal Growth Factor Receptor-Dependent Sebaceous Gland Hyperplasia
    Maik Dahlhoff, Daniela Frances, Jennifer Elisabeth Kloepper, Ralf Paus, Matthias Schäfer, Catherin Niemann, Marlon Roberto Schneider · 2014 · Molecular and Cellular Biology
61. Role of TGF-alpha in the progression of diabetic kidney disease
    Josef G. Heuer, Shannon M. Harlan, Derek D. Yang, Dianna L. Jaqua, Jeffrey S. Boyles, Jonathan Matthew Wilson, Kathleen Marie Heinz-Taheny, John M. Sullivan, Tao Wei, Hui-Rong Qian et al. · 2017 · American Journal of Physiology-Renal Physiology
62. Nanotechnology in metastatic cancer treatment: Current Achievements and Future Research Trends
    Diana Gonciar, Teodora Mocan, Cristian Tudor MATEA, Claudiu Zdrehuş, Ofelia Moșteanu, Lucian Constantin MOCAN, Teodora Pop · 2019 · Journal of Cancer
63. Rapidly activated epidermal growth factor receptor mediates lipopolysaccharide-triggered migration of microglia
    Wensheng Qu, Junli Liu, Chunyu Li, Xiao Li, Min-Jie Xie, Wei Wang, Dai‐Shi Tian · 2015 · Neurochemistry International
64. The ABC of BTC: Structural properties and biological roles of betacellulin
    Maik Dahlhoff, Eckhard Wolf, Marlon Roberto Schneider · 2014 · Seminars in Cell and Developmental Biology
65. EGFR as therapeutic target to develop new generation tyrosine kinase inhibitors against breast cancer: A critical review
    Ruby Mariam Raju, Jeffin Joy A, Nulgumnalli Manjunathaiah Raghavendra, Antony Justin, B. R. Prashantha Kumar · 2024 · Results in Chemistry
66. Inhibition of EGFR Tyrosine Kinase by Erlotinib Prevents Sclerodermatous Graft-Versus-Host Disease in a Mouse Model
    Florence Morin, Niloufar Kavian, Wioleta Marut, Christiane Chéreau, Olivier Cerles, P. Grange, Bernard J. Weill, Carole Nicco, Frédéric Batteux · 2015 · Journal of Investigative Dermatology
67. Embryo arrest and reactivation: potential candidates controlling embryonic diapause in the tammar wallaby and mink†
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68. Exosomes at a glance – common nominators for cancer hallmarks and novel diagnosis tools
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69. Cardiac GPCR–Mediated EGFR Transactivation: Impact and Therapeutic Implications
    Laurel A. Grisanti, Shuchi Guo, Douglas G. Tilley · 2017 · Journal of Cardiovascular Pharmacology
70. Regulation of Receptor Tyrosine Kinase Ligand Processing
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71. Membrane Interacting Peptides: From Killers to Helpers
    Érick J. Dufourc, Sébastien Buchoux, Jeannot Toupé, Marc‐Antoine Sani, Frantz Louis Jean-Francois, Lucie Khemtémourian, Axelle Grélard, Cécile Courrèges, Michel S. Laguerre, Juan Elezgaray et al. · 2012 · Current Protein and Peptide Science
72. Drug-screening and genomic analyses of HER2-positive breast cancer cell lines reveal predictors for treatment response
    Sandra Jernström, Vesa Hongisto, Suvi‐Katri Leivonen, Eldri Undlien Due, Dagim Shiferaw Tadele, Henrik Edgren, Olli Kallioniemi, Merja Perälä, Gunhild Mari Mælandsmo, Kristine Kleivi Sahlberg · 2017 · Breast Cancer Targets and Therapy
73. Molecular Imaging of Hepatocellular Carcinoma Xenografts with Epidermal Growth Factor Receptor Targeted Affibody Probes
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74. Cutaneous consequences of inhibiting EGF receptor signaling in vivo: Normal hair follicle development, but retarded hair cycle induction and inhibition of adipocyte growth in EgfrWa5 mice
    Koji Sugawara, Marlon Roberto Schneider, Maik Dahlhoff, Jennifer Elisabeth Kloepper, Ralf Paus · 2010 · Journal of Dermatological Science
75. Integrin α1β1 protects against signs of post-traumatic osteoarthritis in the female murine knee partially via regulation of epidermal growth factor receptor signalling
    So–Youn Shin, Ambra Pozzi, Steven K. Boyd, A.L. Clark · 2016 · Osteoarthritis and Cartilage
76. Neuropathologic Implication of Peripheral Neuregulin-1 and EGF Signals in Dopaminergic Dysfunction and Behavioral Deficits Relevant to Schizophrenia: Their Target Cells and Time Window
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77. Feedback control of ErbB2 via ERK-mediated phosphorylation of a conserved threonine in the juxtamembrane domain
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78. Critical roles for EGFR and EGFR–HER2 clusters in EGF binding of SW620 human carcinoma cells
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79. Migration of retinal pigment epithelial cells is EGFR PI3K AKT dependent
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80. Engineered Bivalent Ligands to Bias ErbB Receptor-mediated Signaling and Phenotypes
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81. Proprotein Convertase PC7 Enhances the Activation of the EGF Receptor Pathway through Processing of the EGF Precursor
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82. EGFR and SYNE2 are associated with p21 expression and SYNE2 variants predict post-operative clinical outcomes in HBV-related hepatocellular carcinoma
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83. Association between circulating neuregulin4 levels and diabetes mellitus: A meta-analysis of observational studies
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84. LINC00885 a Novel Oncogenic Long Non-Coding RNA Associated with Early Stage Breast Cancer Progression
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85. Activated EGFR stimulates MUC1 expression in human uterine and pancreatic cancer cell lines
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86. Analysis of the anti-tumor effect of cetuximab using protein kinetics and mouse xenograft models
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87. Epidermal growth factor receptor tyrosine-kinase inhibitor treatment resistance in non-small cell lung cancer: biological basis and therapeutic strategies
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88. Regulatory mechanisms of betacellulin in CXCL8 production from lung cancer cells
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89. Mammary tumorigenesis induced by fibroblast growth factor receptor 1 requires activation of the epidermal growth factor receptor
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90. Sperm Epidermal Growth Factor Receptor (EGFR) Mediates α7 Acetylcholine Receptor (AChR) Activation to Promote Fertilization
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91. Whole genome and whole transcriptome genomic profiling of a metastatic eccrine porocarcinoma
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92. Blood‐based markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance)
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93. Combining Mutational Signatures, Clonal Fitness, and Drug Affinity to Define Drug-Specific Resistance Mutations in Cancer
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94. FUT8 Remodeling of EGFR Regulates Epidermal Keratinocyte Proliferation during Psoriasis Development
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95. Mutations of NRG4 Contribute to the Pathogenesis of Nonalcoholic Fatty Liver Disease and Related Metabolic Disorders
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96. Pharmacogenomics of EGFR-targeted therapies in non–small cell lung cancer: EGFR and beyond
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97. MiR-129 regulates MMP9 to control metastasis of non-small cell lung cancer
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98. ERBB Receptor Activation Is Required for Profibrotic Responses to Transforming Growth Factor β
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99. Genetic Modification of CD8+ T Cells to Express EGFR: Potential Application for Adoptive T Cell Therapies
    Teresa Lozano, Silvia Chocarro, Celia Martín-Otal, Aritz Lasarte-Cía, Cynthia del Valle, Marta Gorraiz, Patricia Sarrión, Marina Ruiz de Galarreta, Amaia Lujambio, Sandra Hervás‐Stubbs et al. · 2019 · Frontiers in Immunology
100. Differential Gene Expression in Cholesteatoma by DNA Chip Analysis
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