The epidermal growth factor receptor ligands at a glance

Schneider, Marlon R., Wolf, Eckhard·2009·Journal of Cellular Physiology

DOI 10.1002/jcp.21635

Cited by (445)

Items 301–400 of 445

Evaluation of the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy After Single and Multiple Dosings of LY3016859 in Healthy Subjects and Patients With Diabetic Nephropathy
Joanne Sloan‐Lancaster, Eyas Raddad, Mark A. Deeg, Michelle Eli, Amy Flynt, James Alan Tumlin · 2018 · Clinical Pharmacology in Drug Development
Mechanism of action of Bu Zhong Yi Qi Decoction in the treatment of chronic fatigue syndrome based on network pharmacology and molecular docking
Jie Zhang, Xiaoju Liu, Xin Li, Zhenhao Ying, Wei Liu · 2022 · Pharmacological Research - Modern Chinese Medicine
Decursin inhibits EGFR‐ERK1/2 signaling axis in advanced human prostate carcinoma cells
Tariq A. Bhat, Arpit Dheeraj, Dhanya K. Nambiar, Surya Pratap Singh, Dongsool Yim, Rana Pratap Singh · 2023 · The Prostate
Identification of putative drug targets for human sperm-egg interaction defect using protein network approach
Soudabeh Sabetian, Mohd Shahir Shamsir · 2015 · BMC Systems Biology
Genistein Produces Hepatoprotection through Modulating EGFR Expression and Phosphorylation in Experimental Fibrosis
Rodriguez Fragoso L, Alvarez Ayala E · 2016 · Journal of Liver
mMAPS: A Flow-Proteometric Technique to Analyze Protein-Protein Interactions in Individual Signaling Complexes
Chao‐Kai Chou, Heng‐Huan Lee, Pei-Hsiang Tsou, Chun‐Te Chen, Jung-Mao Hsu, Hirohito Yamaguchi, Ying‐Nai Wang, Hong-Jen Lee, Jennifer L. Hsu, Jin-Fong Lee et al. · 2014 · Science Signaling
Small Molecule Inhibitors of the Epidermal Growth Factor Receptor
M. Raymond V. Finlay, Richard A. Ward · 2017 · Topics in medicinal chemistry
ErbB3 Ligand Heregulin1 Is a Major Mitogenic Factor for Uncontrolled Lung Cancer Cell Proliferation
Shiqi Ma, Shijun Jia, Yuan Ren, Bangrong Cao, Xiao Zha, Jintao He, Changmin Chen · 2019 · Neoplasia
Advances in supplementation strategies for enhancing bovine in vitro embryo production: a review of growth factors and antioxidants
O. Kereilwe · 2025 · Journal of Assisted Reproduction and Genetics
Development of a novel anti-erythropoietin-producing hepatocellular receptor B6 monoclonal antibody Eb6Mab-3 for flow cytometry
Tomohiro Tanaka, Yu Kaneko, Haruto Yamamoto, Guanjie Li, Shiori Fujisawa, Hiroyuki Satofuka, Keisuke Shinoda, Takuya Nakamura, Mika Kato Kaneko, Hiroyuki Suzuki et al. · 2025 · Biochemistry and Biophysics Reports
PEG-SOD attenuates the mitogenic ERK1/2 signaling cascade induced by cyclosporin A in the liver and kidney of albino mice
Ahmed K. Yousef, Ibrahim G. Saleh, Adel R. A. Abd‐Allah, Mohamed R. Elnagar, El‐Sayed Akool · 2020 · Chemico-Biological Interactions
Stimulatory effects of TGFα in granulosa cells of bovine small antral follicles
Allie L Lundberg, Nicole Morin Jaskiewicz, Abigail M. Maucieri, David H. Townson · 2022 · Journal of Animal Science
LINC01608 activated by YY1 facilitate hepatocellular carcinoma progression by modulating the EGFR/ERK axis
Mengzhen Han, Furong Liu, Xinxin Li, Hongwei Zhang, Yonglong Pan, Yachong Liu, He Zhu, Huifang Liang, Xiaoping Chen, Zhibin Liao et al. · 2022 · Liver International
Evolution of Receptor Tyrosine Kinases
Manfred Schartl, Jean‐Nicolas Volff, Frédéric Brunet · 2014 · Springer eBooks
The magnificent seven: Epidermal growth factor receptor ligands
Marlon Roberto Schneider · 2014 · Seminars in Cell and Developmental Biology
Potential for functional redundancy in EGF and TGFα signaling in desmoid cells: a cDNA microarray analysis
Sylvia H. Trang, David E. Joyner, Timothy A. Damron, Albert J. Aboulafia, Robert Lor Randall · 2009 · Growth Factors
Amphiregulin induces interleukin-8 production and cell proliferation in lung epithelial cells through PI3K-Akt/ ERK pathways
Fangfang Yang, Wei Xu, Yanli Pei · 2021 · European Journal of Inflammation
Therapeutic targets and signaling mechanisms of dasatinib activity against radiation skin ulcer
Wenxing Su, Xuelian Chen, Wen Zhang, Dazhuang Li, Xiaoming Chen, Daojiang Yu · 2022 · Frontiers in Public Health
Determination of both the expression and serum levels of epidermal growth factor and transforming growth factor β1 genes in COVID-19
Pınar Yıldız Gülhan, Recep Eröz, Cihadiye Elif Öztürk, Dilek YEKENKURUL, Hasan Baki Altınsoy, Ege Güleç Balbay, Merve Erçelik, Fatih Davran, Şeyma Yıldız · 2025 · Scientific Reports
Mechanisms for DNA‑damaging agent‑induced inactivation of ErbB2 and ErbB3 via the ERK and p38 signaling pathways
Chul Min Park, Yuki Kawasaki, Alaa Refaat, Hiroaki Sakurai · 2017 · Oncology Letters
Image-Based Profiling Can Discriminate the Effects of Inhibitors on Signaling Pathways under Differential Ligand Stimulation
Kenji Tanabe, Ayane Inagaki, Yuji Henmi, Masanobu Satake · 2018 · SLAS DISCOVERY
Characterization of the roles of amphiregulin and transforming growth factor β1 in microvasculature-like formation in human granulosa-lutein cells
Hui Li, Hsun‐Ming Chang, Saijiao Li, Christian Klausen, Zhendan Shi, Peter C. K. Leung · 2022 · Frontiers in Cell and Developmental Biology
Myeloid cell-specific deletion of epidermal growth factor receptor aggravates acute cardiac injury
Ama Dedo Okyere, Tapas Kumar Nayak, Viren Patwa, David Teplitsky, Erin McEachern, Rhonda L. Carter, Heli Xu, Erhe Gao, Yan Zhou, Douglas G. Tilley · 2023 · Clinical Science
Nanoparticulate targeted drug delivery using peptides and proteins
Hélder A. Santos, Luís M. Bimbo, José das Neves, Bruno Filipe Carmelino Cardoso Sarmento, INEB · 2012 · Elsevier eBooks
Adverse effects of anti-cancer biologics on the ocular surface
Riham Shawer, Abraham Solomon · 2024 · Current Opinion in Allergy and Clinical Immunology
Functional Aspects of the EGF-Induced MAP Kinase Cascade: A Complex Self-Organizing System Approach
Efstratios K. Kosmidis, Moschou Vasiliki, Ziogas Georgios, Ioannis Boukovinas, Maria Albani, Nikolaos Laskaris · 2014 · PLoS ONE
Preparation and identification of an anti-idiotypic antibody antagonist (FG8) for EGFR that shows potential activity against liver cancer cells
Yurong Wang, Fangping He, Helin Zhang, Ying Cao, Yaqing Zhang, Yun Ling, Aliya Rehati · 2020 · Biotechnology Letters
EGF/EGFR signaling axis is a significant regulator of the proteasome expression and activity in colon cancer cells
Maria-Ioanna Ellina, Panagiotis Bouris, Dimitrios Kletsas, Alexios J. Aletras, Nikos K. Karamanos · 2014 · ScienceOpen Research
The C‐terminal cytoplasmic domain of human proEGF is a negative modulator of body and organ weights in transgenic mice
Thomas C. Klonisch, Aleksandra Głogowska, Ana Angélica Gratão, Marjeta Grzech, Andreea Nistor, Mark G. Torchia, Ekkehard Weber, Martin Hrabě de Angelis, Birgit Rathkolb, Cuong Hoang-Vu et al. · 2009 · FEBS Letters
Loss of p16INK4a in neuroblastoma cells induces shift to an immature state with mesenchymal characteristics and increases sensitivity to EGFR inhibitors
Nil A. Schubert, Sander R. van Hooff, Linda G. Schild, Kimberley Ober, Marjolein Hortensius, Kim van den Handel, Anke H. W. Essing, Bianca Koopmans, Manon Boeije, Natalie Proost et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
Peptide-Specific Vaccines
Patrick Roth, Michael Weller · 2017 · Elsevier eBooks
The epidermal growth factor ortholog of ectromelia virus activates EGFR/ErbB1 and demonstrates mitogenic function in vitro
Rebecca A. Morgis, Kaylyn Haan, Julie M. Schrey, Rosie M. Zimmerman, Adam R. Hersperger · 2021 · Virology
Receptor Tyrosine Kinases and the Insulin Signaling System
Morris F. White · 2018 · Endocrinology
Functional EGF domain of the human neuregulin 1α produced in Escherichia coli with accurate disulfide bonds
Arthur Schveitzer Ferreira, Amanda Lopacinski, Michel Batista, Priscila Mazzochi Hiraiwa, Natalia Fernanda Bueno, Beatriz Gomes Guimarães, Nilson Ivo Tonin Zanchin · 2022 · Molecular Biology Reports
RSV Induces Activation of Intracellular EGFR on the Mitochondrial Membrane for Virus Propagation
Se Sil Noh, Hye Jin Shin · 2023 · International Journal of Molecular Sciences
Evaluation of the modulating effect of epidermal growth factor receptor inhibitor cetuximab in carbon-tetrachloride induce hepatic fibrosis in rats
Mirza Alimullah, Asif Ul Haque Shuvo, Ishrat Jahan, Iffat Nowshin Ismail, S.M. Mufidul Islam, Mahnaj Sultana, Mahmudur Rahman Saad, Sabbir Raihan, Ferdous Khan, Md Ashraful Alam et al. · 2024 · Biochemistry and Biophysics Reports
Anti-HDGF Antibody Targets EGFR Tyrosine Kinase Inhibitor–Tolerant Cells in NSCLC Patient-Derived Xenografts
Cindy Q. Zhou, Ariel Li, Kaoru Ri, Ahmed S. Sultan, Hening Ren · 2024 · Cancer Research Communications
Impaired wound healing in Parkinson’s disease: a hypothesis on altered epidermal growth factor (EGF) and N-methyl-D-aspartate (NMDA) signaling in keratinocytes
Caroline Liu, Johanna Ghebrehiwet-Kuflom, R. Rivkah Isseroff, Sara E. Dahle, Vera B. Morhenn · 2025 · Molecular Medicine
Role of Growth Factor Signaling Pathways in Biliary Tract Cancer
Kaoru Kiguchi, John DiGiovanni · 2014 · Medical radiology
Betacellulin transgenic mice develop urothelial hyperplasia and show sex-dependent reduction in urinary major urinary protein content
Helene Schulz, Maik Dahlhoff, Aleksandra Głogowska, Lin Zhang, Georg Josef Arnold, Thomas Fröhlich, Marlon Roberto Schneider, Thomas C. Klonisch · 2015 · Experimental and Molecular Pathology
EGFR (ErbB) Signaling Pathways in Pancreatic Cancer Pathogenesis
Monique Williams, Gwen Alyce Lomberk, Raul A. Urrutia · 2017 · Springer eBooks
Cloning and Expression of the Variable Regions of Anti-EGFR Monoclonal Antibody in E. coli for Production of a Single Chain Antibody
Farzaneh Jalalypour, Safar Farajnia, Fatemeh Mahmoudi, Behzad Baradaran, Leila Rahbarnia, Jafar Majidi · 2014 · Iranian Journal of Biotechnology
Mechanisms of Action and Resistance of Trastuzumab in Breast Cancer
Jennifer L. Hsu, Mien‐Chie Hung · 2018 · Resistance to targeted anti-cancer therapeutics
Physiological functions of keratinocyte epidermal growth factor receptors and their role in the development of skin toxicity during targeted cancer therapy
Ekaterina V. Orlova · 2021 · Russian Journal of Skin and Venereal Diseases
Manufacturable Process of a Novel EGFR Inhibitor (Larotinib) for the Treatment of ESCC
Weihong Zhang, Zhi-Ming Su, Haiwang Liu, Ying‐Jun Zhang, Weiliang Ye, Dahua Peng, Hongpeng Xie, Hongtao Peng, Zhihong Peng, Wanrong Dong et al. · 2022 · Organic Process Research & Development
Celastrol attenuates amphiregulin expression by inhibiting MAPK signaling pathway in triple-negative breast cancer cells
Sangmin Kim, Daeun You, Yisun Jeong, Sun Young Yoon, Eunji Lo, Jeong Eon Lee · 2022 · Phytomedicine Plus
Searching for Biomarkers in Proliferative Diabetic Retinopathy: Amphiregulin and Progranulin
Burak Bilgin, Mete Güler, Hulya CICEK, Selma Urfalıoğlu, Gökhan Köküsarı · 2022 · Medeniyet Medical Journal
Advances in Research on Aging in Female Infertility and Pathologic Pregnancy
2024 · Frontiers research topics
Master Thesis in Pharmacy
Anna S. Wilhelmson · 2008
Epiregulin: A new prognostic molecule in non-Hodgkin lymphoma
İsmail Demir, Özden Yıldırım Akan, Ferda Bilgir, İsmail Yılmaz, Giray Bozkaya, Oktay Bilgir · 2024 · Irish Journal of Medical Science (1971 -)
The expression of congenital Shoc2 variants induces AKT-dependent crosstalk activation of the ERK1/2 pathway
Patricia G. Wilson, Lina G. Abdelmoti, Tianyan Gao, Emilia Galperin · 2024 · Human Molecular Genetics
Analysis of Histochemical Characteristics of Submandibular Gland of the Bactrian Camel
Yulu Chen, Guojuan Chen, Yumei Qi, Jianlin Zeng, Long Ma, Xudong Zhang, Xiaolong Qie, Yajuan Jin, Haijun Li, Ligang Yuan · 2025 · Veterinary Sciences
Chiral Nanoagonist Targeting EGFR for Nerve Injury Repair
Xiaoyu Zhao, Yue Wang, Jie Bian, Liming Miao, Yu Wang, Taka‐aki Ishibashi, Lie Wu, Xiue Jiang · 2025 · Advanced Materials
Inflammaging and Senescence-Associated Secretory Phenotype (SASP) in Psoriasis – A Narrative Review of Potential Mechanisms and Anti-Inflammaging Strategies
Kinga Filipek, Julia Nowowiejska, Iwona Flisiak · 2026 · Psoriasis Targets and Therapy
Matrix metalloproteinases and collective cell migration in 24 h primary zebrafish explant cultures: MMP13 plays an inhibitory role and MMP14 may respond to stretch during reepithelialisation
Timothy M. McDonald, Adam J. Sumner, Jonazary F. Reyes, Agnes S. Pascual, Chandana K. Uppalapati, Kimbal E. Cooper, Kathryn J. Leyva, Elizabeth E. Hull · 2013 · Cell Biology International Reports
Inhibition of EGFR Suppresses Ethyl Alcohol and Tobacco Cell Effects on Growth of Human Oral Keratinocytes and Human Papillomavirus 16 Entry as a Function of Furin
JOEL L. SCHWARTZ, Alexander M. Munaretto, Sirlata Bagchi, David L. Crowe, Gonzalo Izaguirre · 2015 · Journal of Cancer Therapy
Effects of DNA damage on oocyte meiotic maturation and early embryonic development
Shen YIN, Junyu MA, Wei SHEN · 2014 · Frontiers of Agricultural Science and Engineering
Epidermal growth factor/epidermal growth factor receptor signaling axis is a significant regulator of the proteasome expression and activity in colon cancer cells
Maria‐Ioanna Ellina, Panagiotis Bouris, Dimitris Kletsas, Alexios J. Aletras, Nikos K. Karamanos · 2014 · ScienceOpen Research
The endothelial-to-mesenchymal transition process
Enrique Arciniegas, Luz Marina Carrillo · 2012 · Revista Latinoamericana de Hipertensión/Revista Latinoamericana de Hipertensiòn
Using Molecular Markers to Guide Therapy of Metastatic Colorectal Cancer
Autumn J. McRee, Bert H. O’Neil · 2013 · The Journal of OncoPathology
The Combined Use of Enhanced Stromal Vascular Fraction and Platelet-Rich Plasma Improves Fat Grafting Maintenance in Breast Reconstruction: A Comparative Translational Study
Valerio Cervelli, Pietro Gentile · 2015 · Springer eBooks
Targeted Therapies for Lung Cancer
Asmita Patel, Eric Bernicker · 2017 · Molecular pathology library
Influence of epidermal growth factor (EGF) supplementation at different times of in vitro maturation of canine oocytes
Leda Maria Costa Pereira, Paulo Ricardo de Oliveira Bersano, Maria Denise Lopes · 2017 · Brazilian Journal of Veterinary Research and Animal Science
The effect of human recombinant epidermal growth factor on capsule contraction in an irradiated rat model
Yavuz Tuluy, Mustafa Kürşat Evrenos, Levent Yoleri, Peyker Temız, Ali Ölmezoğlu · 2023 · European Journal of Plastic Surgery
Interaction between epidermal growth factor receptor and C-C motif chemokine receptor 2 in the ovulatory cascade
Julia G Conte, Mariana Lorena Tellechea, Brian Park, Marı́a Gabriela Ballerini, Gabriela Jaita, Marina Cinthia Peluffo · 2023 · Frontiers in Cell and Developmental Biology
In silico Characterization of Esophageal Cancer Predominant Genes
Gizem KÖPRÜLÜLÜ KÜÇÜK · 2023 · Sakarya University Journal of Science
Paradoxical Trichomegaly of the Eyelashes During Treatment with EGFR Inhibitors: 2 Case Report
Kun Hoo Na, Youngsub Eom, Su Yeon Kang, Hyo Myung Kim, Jong Suk Song · 2014 · Journal of the Korean Ophthalmological Society
Les facteurs de croissance et les récepteurs à activité tyrosine kinase
Jacques Robert · 2010 · Springer eBooks
Growth Factors and Tyrosine Kinase Receptors
Jacques Robert · 2014 · Springer eBooks
Markers of Sensitivity and Resistance to EGFR Inhibitors in Colorectal Cancer
Jose Gerard Monzon, Janet Ellen Dancey · 2020
The Interplay Between Oviduct-Derived Exosomes and Cumulus-Oocyte Complexes
Seok Hee Lee, Byeong Chun Lee · 2020 · Springer eBooks
Markers of Sensitivity and Resistance to EGFR Inhibitors in Colorectal Cancer
Jose Gerard Monzon, Janet Ellen Dancey · 2013 · Pan Stanford Publishing eBooks
Protein dynamics studied by coarse-grained and atomistic theoretical approaches
Laura Orellana · 2014 · Dipòsit Digital de la Universitat de Barcelona (Universitat de Barcelona)
MR Molecular Imaging of EGF Receptor-Overexpressing Tumours with Peptide-Targeted Gadolinium-Based Contrast Agents
Yang Fan, Chunping Liu, tingshuo yao, Jianli Duan, Shibin Ai, Xin Liu · 2024
Investigations into the role of the ErbB4 receptor in cardiomyocyte hypertrophy and adult cardiac function
Zhen Wang · 2015 · The University of Queensland
MOLECULAR MECHANISM OF CYTOKINE PRODUCTION BY HUMAN LUNG FIBROBLAST IN RESPONSE TO PSEUDOMONAS AERUGINOSA ELASTASE
Kourtney Bass · 2015 · Scholar Works at UT Tyler (The University of Texas at Tyler)
A Role For Lipid Rafts In Egfr Tki Resistance In Breast Cancer
Mary E. Irwin · 2010 · Human Biology
The role of the Homeobox gene HOXD10 in Lung and Head & Neck carcinoma
Fahad Hakami · 2013 · White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)
Characterization of the Molecular Genetic Mechanisms that Contribute to Pancreatic Cancer Carcinogenesis
Jiaming Qian, Hong Bo Yang, Jingnan Li, Jian Wang · 2012 · InTech eBooks
The mechanism of signal transduction by the GPI anchored Prod 1 protein
Robert A. Blassberg · 2010 · UCL Discovery (University College London)
Analysis of a new transgenic mouse model with ß-cell-specific overexpression of human betacellulin
Marjeta Grzech · 2010 · Electronic Theses of LMU Munich (Ludwig-Maximilians-Universität München)
Effects of epidermal growth factor on adult neural stem cells
Olle R. Lindberg · 2013 · Gothenburg University Publications Electronic Archive (Gothenburg University)
Avaliação da expressão dos genes envolvidos na via de sinalização induzida pela proteína dermicidina no câncer de mama.
Dayson Moreira · 2012
EGF +61A/G polymorphism contributes to increased gastric cancer risk: evidence from a
Qiliu Peng, Shan Li, Xue Ying Qin, Xianjun Lao, Zhiping Chen, Xiao‐Lian Zhang, Junqiang Chen · 2014
Analysis of a new transgenic mouse model with β-cell-specific overexpression of human betacellulin
Ludwig-Maximilians-Universität München, Eckhard Wolf · 2009
Stress-inducible Mig6 promotes pancreatic beta cell destruction in the pathogenesis of diabetes
Yi‐Chun Chen · 2014
AVALIAÇÃO DA EXPRESSÃO DOS GENES ENVOLVIDOS NA VIA DE SINALIZAÇÃO INDUZIDA PELA PROTEÍNA DERMICIDINA NO CÂNCER DE MAMA
São Paulo · 2011
The Role of Integrin alpha1beta1 and Epidermal Growth Factor Receptor Signalling in Post-traumatic Osteoarthritis
Shin, Sung Yong · 2015 · Libraries and Cultural Resources (University of Calgary)
[99mTc/90Y]-1,4,7,10 Tetraazacyclododecane-N,N’,N’’,N’’’-tetraacetic acid phenylalanine derivative conjugated to anti-epidermal growth factor receptor antibody ior egf/r3
Puja Panwar, Normando Iznaga-Escobar, Pushpa Mishra, Vibha Srivastava, Rakesh Kumar Sharma, Ramesh Chandra, Anil Kumar Mishra, Arvind Chopra · 2009 · Europe PMC (PubMed Central)
The role of TAM receptors in brain tumour cell signalling and behaviour
Mikaella Vouri · 2016
The Role of Signaling Pathway Integration in Neurogenesis
Randy Ringuette · 2016 · uO Research (University of Ottawa)
Receptor Tyrosine Kinases and the Insulin Signaling System
Morris F. White · 2017 · Endocrinology
The effects of a high carbohydrate and high fat diet and dietary interventions in the molecular tumourigenesis of colorectal cancer
Amanda Dieckmann · 2016
Additive effects among uterine paracrine factors in promoting bovine trophoblast cell proliferation
Markus Ming Xie · 2014 · VTechWorks (Virginia Tech)
Egf regulates purine and pyrimidine metabolism
Danielyan Ke · 2017
Recruitment, phenotype and function of tumour-infiltrating regulatory T cells in the lung microenvironment
Elizabeth C. Halvorsen · 2018 · cIRcle (University of British Columbia)
EGF signalling in epithelial carcinoma cells utilizes preformed receptor homoclusters, with larger heteroclusters post activation
Charlotte Fournier, Adam J. M. Wollman, Isabel Llorente‐Garcia, Oliver L. Harriman, Djamila Ouarat, Jenny Wilding, Walter Fred Bodmer, Mark C. Leake · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
Epidermal growth factor-like ligands regulate dimer selection.
Jamie S. Rush · 2018
Monoclonal Antibodies in Cancer
Jürgen Barth · 2019 · Springer eBooks
Targeting Cancer from a Structural Biology Perspective
Derion F Reid, Carla Mattos · 2019 · Springer eBooks