The DOI matches its Crossref record; 123 of the 123 references it cites were found in a registry or an index.
Epithelial–mesenchymal transition (EMT): A biological process in the development, stem cell differentiation, and tumorigenesis
Open accessAbstract
The lineage transition between epithelium and mesenchyme is a process known as epithelial–mesenchymal transition (EMT), by which polarized epithelial cells lose their adhesion property and obtain mesenchymal cell phenotypes. EMT is a biological process that is often involved in embryogenesis and diseases, such as cancer invasion and metastasis. The EMT and the reverse process, mesenchymal–epithelial transition (MET), also play important roles in stem cell differentiation and de‐differentiation (or reprogramming). In this review, we will discuss current research progress of EMT in embryonic development, cellular differentiation and reprogramming, and cancer progression, all of which are representative models for researches of stem cell biology in normal and in diseases. Understanding of EMT and MET may help to identify specific markers to distinguish normal stem cells from cancer stem cells in future.
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1 retracted
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Cited by
Yu, C.-Y., Chang, W.-C., Zheng, J.-H., Hung, W.-H., & Cho, E.-C. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.10.137 · Cited by 19
Metabolic reprogramming: The driving force behind cancer drug resistance
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Metadata
- Authors
- Chen, T., You, Y., Jiang, H., & Wang, Z. Z.
- Venue
- Journal of Cellular Physiology
- Publisher
- Wiley
- Published
- 2017-04-10
- Volume
- 232
- Issue
- 12
- Pages
- 3261-3272
- ISSN
- 0021-9541 (ISSN-L)
- 1097-4652
- OpenAlex
- W2573970795
- Cited by
- 560
- References
- 123
- FWCI
- 21.54
- Type
- journal article
- Language
- en
- Open access
- green
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- Chen, T., You, Y., Jiang, H., & Wang, Z. Z. (2017). Epithelial–mesenchymal transition (EMT): A biological process in the development, stem cell differentiation, and tumorigenesis. Journal of Cellular Physiology. https://doi.org/10.1002/jcp.25797
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
