Macrophage plasticity, polarization, and function in health and disease

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Items 801–900 of 1,011

1. Understanding the Role of Innate Immune Cells and Identifying Genes in Breast Cancer Microenvironment
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2. Contribution of Extramedullary Hematopoiesis to Atherosclerosis. The Spleen as a Neglected Hub of Inflammatory Cells
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3. Amygdalin Attenuates Atherosclerosis and Plays an Anti-Inflammatory Role in ApoE Knock-Out Mice and Bone Marrow-Derived Macrophages
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4. Macrophage Activation in the Synovium of Healthy and Osteoarthritic Equine Joints
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5. T Cells as Guardians of Pain Resolution
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6. The role of macrophage-derived TGF-β1 on SiO 2 -induced pulmonary fibrosis: A review
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7. Down-regulation of TNF-α via macrophage-targeted RNAi system for the treatment of acute inflammatory sepsis
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8. Plasma extracellular vesicles released after severe burn injury modulate macrophage phenotype and function
   Micah L. Willis, Cressida Mahung, Shannon Margaret Wallet, Alexandra Barnett, Bruce A Cairns, Leon G. Coleman, Robert Maile · 2021 · Journal of Leukocyte Biology
9. HA-coated collagen nanofibers for urethral regeneration via in situ polarization of M2 macrophages
   Yuqing Niu, Florian J. Stadler, Xu Yang, Fuming Deng, Guochang Liu, Huimin Xia · 2021 · Journal of Nanobiotechnology
10. Deficiency of Calcitonin Gene-Related Peptide Affects Macrophage Polarization in Osseointegration
    Ying Yuan, Yixuan Jiang, Bin Wang, Yanjun Guo, Ping Gong, Lin Xiang · 2020 · Frontiers in Physiology
11. Berberine promotes M2 macrophage polarisation through the IL-4-STAT6 signalling pathway in ulcerative colitis treatment
    Kai Xiong, Jia Deng, Tinghui Yue, Wenting Hu, Xinglin Zeng, Tao Yang, Tianbao Xiao · 2023 · Heliyon
12. Tumour microenvironment changes after osimertinib treatment resistance in non-small cell lung cancer
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13. Activation and Regulation of Pancreatic Stellate Cells in Chronic Pancreatic Fibrosis: A Potential Therapeutic Approach for Chronic Pancreatitis
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14. Exosomes derived from tendon stem/progenitor cells enhance tendon-bone interface healing after rotator cuff repair in a rat model
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15. Biomaterials that passively and actively target macrophages promote the regeneration of injured tissues
    Pengzhen Zhuang, Yang Wu, Yu Chen, Yu Zhang, Capucine Leboucher, Jessica M. Rosenholm, Hongbo Zhang · 2024 · Biomedical Technology
16. Role of the Receptor for Advanced Glycation End Products (RAGE) and Its Ligands in Inflammatory Responses
    Kaylen Cross, Stefan W. Vetter, Yousuf Alam, Md. Zahidul Hasan, Anupom Deb Nath, Estelle Leclerc · 2024 · Biomolecules
17. An unbalanced monocyte macrophage polarization in the bone marrow microenvironment of patients with poor graft function after allogeneic haematopoietic stem cell transplantation
    Hongyan Zhao, Zhong‐Shi Lyu, Cai‐Wen Duan, Yang Song, Ting‐Ting Han, Xiao‐Dong Mo, Yu Wang, Lan‐Ping Xu, Xiaohui Zhang, Xiao‐Jun Huang et al. · 2018 · British Journal of Haematology
18. Profiling the human hair follicle immune system in lichen planopilaris and frontal fibrosing alopecia: can macrophage polarization differentiate these two conditions microscopically?
    Matthew J Harries, Jonathan Alan Hardman, I. Chaudhry, Enrique Poblet, Ralf Paus · 2019 · British Journal of Dermatology
19. Lactoferrin-containing immunocomplex mediates antitumor effects by resetting tumor-associated macrophages to M1 phenotype
    Hongliang Dong, Yueyao Yang, Chen‐Hui Gao, Hehe Sun, Hongmin Wang, Chao Hong, Jun Wang, Fang‐Yuan Gong, Xiao‐Ming Gao · 2020 · Journal for ImmunoTherapy of Cancer
20. Histone methyltransferases G9a mediated lipid-induced M1 macrophage polarization through negatively regulating CD36
    Xiuling Wang, Shanshan Chen, Jinrong He, Weiqun Chen, Yu Ding, Juan Huang, Jin Huang · 2020 · Metabolism
21. Engineered Cytokines for Cancer and Autoimmune Disease Immunotherapy
    Biaggio Uricoli, Lacey A. Birnbaum, Priscilla Do, James Kelvin, Juhi Jain, Emma Costanza, Andrew Chyong, Christopher C. Porter, Sarwish Rafiq, Erik C. Dreaden · 2021 · Advanced Healthcare Materials
22. Alpha defensin-1 attenuates surgically induced osteoarthritis in association with promoting M1 to M2 macrophage polarization
    Jing Xie, Y. Wang, Kaiwen Xiao, Hongtao Xu, Zeyu Luo, L. Li, Fuxing Pei, Virginia B. Kraus, Zeyu Huang · 2021 · Osteoarthritis and Cartilage
23. Peripheral neuroimmune interactions: selected review and some clinical implications
    Kamal Shouman, Eduardo Elias Benarroch · 2021 · Clinical Autonomic Research
24. Berberine regulates PADI4-related macrophage function to prevent lung cancer
    Wenwen Gu, Mengdi Zhang, Fan Gao, Yuji Niu, Luyao Sun, Haojie Xia, Wenwen Li, Yaru Zhang, Zhenzhen Guo, Gangjun Du · 2022 · International Immunopharmacology
25. 3D printing of gear-inspired biomaterials: Immunomodulation and bone regeneration
    Xiaopeng Yu, Yufeng Wang, Meng Zhang, Hongshi Ma, Chun Feng, Bingjun Zhang, Xin Wang, Bing Ma, Qingqiang Yao, Chengtie Wu · 2022 · Acta Biomaterialia
26. Knee Alignment Correction by High Tibial Osteotomy Reduces Symptoms and Synovial Inflammation in Knee Osteoarthritis Accompanied by Macrophage Phenotypic Change From M1 to M2
    Shigeo Yoshida, Kohei Nishitani, Hiroyuki Yoshitomi, Shinichi Kuriyama, Shinichiro Nakamura, Takayuki Fujii, Motoo Saito, Yu Kobori, Akinori Murakami, Koichi Murata et al. · 2022 · Arthritis & Rheumatology
27. Programmed cell death and lipid metabolism of macrophages in NAFLD
    Zhun Xiao, Minghao Liu, Fangming Yang, Guangwei Liu, Jiangkai Liu, Wenxia Zhao, Suping Ma, Zhongping Duan · 2023 · Frontiers in Immunology
28. Intracellular Antioxidant and Anti-Inflammatory Effects and Bioactive Profiles of Coffee Cascara and Black Tea Kombucha Beverages
    Amanda Luísa Sales, Amaia Iriondo‐DeHond, Juliana DePaula, Mafalda Ribeiro, Isabel M.P.L.V.O. Ferreira, Marco Antônio Lemos Miguel, M. Dolores del Castillo, Adriana Farah · 2023 · Foods
29. The macrophage polarization by miRNAs and its potential role in the treatment of tumor and inflammation (Review)
    Chaozhe Wang, Xidi Wang, Danfeng Zhang, Xiaolin Sun, Yunhua Wu, Jing Wang, Qing Li, Guosheng Jiang · 2023 · Oncology Reports
30. Macrophage polarisation and inflammatory mechanisms in atherosclerosis: Implications for prevention and treatment
    Bo Yang, Sanhua Hang, Siting Xu, Yun Gao, Wenhua Yu, Guangyao Zang, Lili Zhang, Zhongqun Wang · 2024 · Heliyon
31. Ceramide signaling in immunity: a molecular perspective
    Himani Thakkar, Vinnyfred Vincent, Bhagirath Chaurasia · 2025 · Lipids in Health and Disease
32. Emerging role of glycosylation in the polarization of tumor-associated macrophages
    Natália Rodrigues Mantuano, Maria Cecília Oliveira-Nunes, Frederico Alisson‐Silva, Wagner B. Dias, Adriane Regina Todeschini · 2019 · Pharmacological Research
33. sEH Inhibitor Tppu Ameliorates Cecal Ligation and Puncture-Induced Sepsis by Regulating Macrophage Functions
    Zhihui Chen, Ying Tang, Jing Yu, Ruolan Dong, Yan Yang, Menglu Fu, Jinlan Luo, Shuiqing Hu, Dao Wen Wang, Ling Tu et al. · 2019 · Shock
34. Optimization of the process for purifying icariin from Herba Epimedii by macroporous resin and the regulatory role of icariin in the tumor immune microenvironment
    Xin Min Zheng, Dihua Li, Jiaxin Li, Botao Wang, Lanqiu Zhang, Xiangfei Yuan, Caixia Li, Lihua Cui, Qi Zhang, Lei Yang et al. · 2019 · Biomedicine & Pharmacotherapy
35. Transfection of hard-to-transfect primary human macrophages with Bax siRNA to reverse Resveratrol-induced apoptosis
    Simon Xin Min Dong, Ramon Edwin Caballero, Hamza Ali, David Lawson Francis Roy, Edana Cassol, Ashok Kumar · 2020 · RNA Biology
36. Exosomal Noncoding RNAs and Tumor Drug Resistance
    Chengyao Guo, Jinbo Liu, Quanbo Zhou, Junmin Song, Zhiyong Zhang, Zhen Li, Guixian Wang, Weitang Yuan, Zhenqiang Sun · 2020 · Cancer Research
37. Fine particulate matter exposure promotes M2 macrophage polarization through inhibiting histone deacetylase 2 in the pathogenesis of chronic obstructive pulmonary disease
    Yan Jiang, Yanfeng Zhao, Qingliang Wang, Hao Chen, Xiao Hui Zhou · 2020 · Annals of Translational Medicine
38. Thyroid Hormone and Deiodination in Innate Immune Cells
    Anne H. van der Spek, Eric Fliers, Anita Boelen · 2020 · Endocrinology
39. The Acute Effects of 5 Fluorouracil on Skeletal Muscle Resident and Infiltrating Immune Cells in Mice
    Brandon N. VanderVeen, Alexander T. Sougiannis, Kandy T. Velázquez, James A. Carson, Daping Fan, E. Angela Murphy · 2020 · Frontiers in Physiology
40. Mesenchymal stem cells cultured in serum-free medium ameliorate experimental peritoneal fibrosis
    Kohei Nagasaki, Ayumu Nakashima, Ryo Tamura, Naoki Ishiuchi, Kiyomasa K. Honda, Toshinori Ueno, Shigehiro Doi, Yukio Kato, Takao Masaki · 2021 · Stem Cell Research & Therapy
41. Subacute cadmium exposure promotes M1 macrophage polarization through oxidative stress-evoked inflammatory response and induces porcine adrenal fibrosis
    Yujie Yao, Xia Zhao, Shufang Zheng, Shengchen Wang, Honggui Liu, Shiwen Xu · 2021 · Toxicology
42. Multimodal Identification by Transcriptomics and Multiscale Bioassays of Active Components in Xuanfeibaidu Formula to Suppress Macrophage-Mediated Immune Response
    Lu Zhao, Hao Liu, Yingchao Wang, Shufang Wang, Dejin Xun, Yi Wang, Yiyu Cheng, Boli Zhang · 2021 · Engineering
43. Inflammation and Myeloid Cells in Cancer Progression and Metastasis
    Jenying Deng, Jason B. Fleming · 2022 · Frontiers in Cell and Developmental Biology
44. Manipulating Macrophage/Microglia Polarization to Treat Glioblastoma or Multiple Sclerosis
    Thomas Kuntzel, Dominique Bagnard · 2022 · Pharmaceutics
45. Dysregulation of mTOR Signaling after Brain Ischemia
    Mario Villa-González, Gerardo Martín-López, María José Pérez-Álvarez · 2022 · International Journal of Molecular Sciences
46. In vitro response of THP-1 derived macrophages to antimicrobially effective PHMB-coated Ti6Al4V alloy implant material with and without contamination with S. epidermidis and P. aeruginosa
    Paula Zwicker, Thomas Schmidt, Melanie Hornschuh, Holger N. Lode, Axel Krämer, Gerald Müller · 2022 · Biomaterials Research
47. A20 inhibits periodontal bone resorption and NLRP3-mediated M1 macrophage polarization
    Liguang Hou, Yu Ye, Huiqing Gou, Hui Tang, Yi Zhou, Xuanwen Xu, Yan Xu · 2022 · Experimental Cell Research
48. Treatment with a JAK1/2 inhibitor ameliorates murine autoimmune cholangitis induced by IFN overexpression
    Tihong Shao, Patrick S.C. Leung, Weici Zhang, Koichi Tsuneyama, William M. Ridgway, Howard A. Young, Zongwen Shuai, Aftab Ahmed Ansari, Merrill Eric Gershwin · 2022 · Cellular and Molecular Immunology
49. Magnetic liposome as a dual-targeting delivery system for idiopathic pulmonary fibrosis treatment
    Xi Wang, Yuying Wang, Zhifeng Xue, Weimin Wan, Yixuan Li, Honglin Qin, Yan Zhu, Fei Tian, Jian Yang · 2023 · Journal of Colloid and Interface Science
50. Macrophage polarization in bone implant repair: A review
    Zhengzheng Song, Yuxi Cheng, Min-Min Chen, Xiaoli Xie · 2023 · Tissue and Cell
51. Acupuncture and its ability to restore and maintain immune homeostasis
    F Liu, Yang Wang, K Lyu, Xuefei Du, Meng Zhou, Jiaqi Shi, R Na, Yongming Guo, Geningyue Wang, Weizhen Xu et al. · 2023 · QJM
52. Reactive oxygen species trigger inflammasome activation after intracellular microbial interaction
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53. Lymphatic vessels: roles and potential therapeutic intervention in rheumatoid arthritis and osteoarthritis
    Siru Zhou, Guangyu Zhao, Ran Chen, Yang Li, Junlan Huang, Liang Kuang, Dali Zhang, Zhijun Li, Haofeng Xu, Wei Xiang et al. · 2023 · Theranostics
54. Immune cells in the epithelial immune microenvironment of psoriasis: emerging therapeutic targets
    Lisha Li, Jiaye Lu, Jun Liu, Junchao Wu, Xinyue Zhang, Yu Meng, Xiying Wu, Zongguang Tai, Quangang Zhu, Zhongjian Chen · 2024 · Frontiers in Immunology
55. Epithelial–mesenchymal plasticity in cancer: signaling pathways and therapeutic targets
    Xiangpeng Wang, Xiaoxia Xue, Mingshi Pang, Liuchunyang Yu, Jinxiu Qian, Xiaoyu Li, Meng Tian, Aiping Lü, Cheng Youn Lu, Yuanyan Liu · 2024 · MedComm
56. Cancer-Associated Fibroblasts: Immunosuppressive Crosstalk with Tumor-Infiltrating Immune Cells and Implications for Therapeutic Resistance
    Jogendra Singh Pawar, Md. Abdus Salam, Md. Shalman Uddin Dipto, Md. Yusuf Al-Amin, Moushumi Tabassoom Salam, Sagnik Sengupta, Smita Kumari, Lohitha Gujjari, Ganesh Yadagiri · 2025 · Cancers
57. Regulation of Hepatic Inflammation via Macrophage Cell Death
    Zhuan Li, Steven A. Weinman · 2018 · Seminars in Liver Disease
58. In Vitro Immunostimulating Activity of Sulfated Polysaccharides from Caulerpa cupressoides Var. Flabellata
    Jefferson da Silva Barbosa, Mariana Santana Santos Pereira Costa, Luciana Fentanes Moura de Melo, Mayara Jane Campos de Medeiros, Daniel de Lima Pontes, Kátia Castanho Scortecci, Hugo Alexandre Oliveira Rocha · 2019 · Marine Drugs
59. Therapeutic Manipulation of Macrophages Using Nanotechnological Approaches for the Treatment of Osteoarthritis
    Aldo Ummarino, Francesco Manlio Gambaro, Elizaveta Kon, Fernando Torres · 2020 · Nanomaterials
60. Children with oligoarticular juvenile idiopathic arthritis have skewed synovial monocyte polarization pattern with functional impairment—a distinct inflammatory pattern for oligoarticular juvenile arthritis
    Tobias Schmidt, Elisabet Berthold, Sabine Arve-Butler, Birgitta Gullstrand, Anki Mossberg, Fredrik Kahn, Anders A Bengtsson, Bengt Månsson, Robin Kahn · 2020 · Arthritis Research & Therapy
61. Serum Irisin Levels, Endothelial Dysfunction, and Inflammation in Pediatric Patients with Type 2 Diabetes Mellitus and Metabolic Syndrome
    Anna Sofia Huerta Delgado, Daniel N. Roffe-Vazquez, Adrian M. González-Gil, José R. Villarreal-Calderón, Oscar Tamez‐Rivera, Nora A. Rodríguez-Gutiérrez, Elena C. Castillo, Christian Silva‐Platas, Gerardo García‐Rivas, Leticia Elizondo‐Montemayor · 2020 · Journal of Diabetes Research
62. Mechanisms of the lipopolysaccharide‑induced inflammatory response in alveolar epithelial cell/macrophage co‑culture
    Jiansheng Li, Yanqin Qin, Yulong Chen, Peng Zhao, Xuefang Liu, Haoran Dong, Wanchun Zheng, Suxiang Feng, Xiaoning Mao, Congcong Li · 2020 · Experimental and Therapeutic Medicine
63. The Degree of Helicobacter pylori Infection Affects the State of Macrophage Polarization through Crosstalk between ROS and HIF-1α
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64. Role of exosomes in the immune microenvironment of ovarian cancer (Review)
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65. Roles of Crosstalk between Astrocytes and Microglia in Triggering Neuroinflammation and Brain Edema Formation in 1,2-Dichloroethane-Intoxicated Mice
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66. Resolvin D1‐loaded nanoliposomes promote M2 macrophage polarization and are effective in the treatment of osteoarthritis
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67. O-GlcNAcylation and Its Role in Cancer-Associated Inflammation
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68. Effects of Anthraquinones on Immune Responses and Inflammatory Diseases
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69. Targeting Angiogenesis via Resolution of Inflammation
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70. Upregulation of large myelin protein zero leads to Charcot–Marie–Tooth disease-like neuropathy in mice
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71. A Role for the Bone Marrow Microenvironment in Drug Resistance of Acute Myeloid Leukemia
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72. Strategies for Biomaterial-Based Spinal Cord Injury Repair via the TLR4-NF-κB Signaling Pathway
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73. Total glucosides of paeony inhibit breast cancer growth by inhibiting TAMs infiltration through NF-κB/CCL2 signaling
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74. Effects of propofol on macrophage activation and function in diseases
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75. Insights into the immunomodulatory regulation of matrix metalloproteinase at the maternal-fetal interface during early pregnancy and pregnancy-related diseases
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76. Exosomes from M2c macrophages alleviate intervertebral disc degeneration by promoting synthesis of the extracellular matrix via MiR ‐124/ CILP / TGF ‐β
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77. EGCG modified small intestine submucosa promotes wound healing through immunomodulation
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78. Lupenone improves motor dysfunction in spinal cord injury mice through inhibiting the inflammasome activation and pyroptosis in microglia via the nuclear factor kappa B pathway
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79. Advances in the application and research of biomaterials in promoting bone repair and regeneration through immune modulation
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80. The role of natural products targeting macrophage polarization in sepsis-induced lung injury
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81. Osthole inhibits pancreatic cancer progression by directly exerting negative effects on cancer cells and attenuating tumor-infiltrating M2 macrophages
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82. Immune Landscape of the Tumor Microenvironment Identifies Prognostic Gene Signature CD4/CD68/CSF1R in Osteosarcoma
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83. High-content and high-throughput identification of macrophage polarization phenotypes
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84. Oral Pathogen Porphyromonas gingivalis Can Escape Phagocytosis of Mammalian Macrophages
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85. Comparative Phenotypic and Functional Analyses of the Effects of IL-10 or TGF-β on Porcine Macrophages
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86. ACVR1R206H extends inflammatory responses in human induced pluripotent stem cell-derived macrophages
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87. NOTCH4 Exhibits Anti-Inflammatory Activity in Activated Macrophages by Interfering With Interferon-γ and TLR4 Signaling
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88. Hexapeptide induces M2 macrophage polarization via the JAK1/STAT6 pathway to promote angiogenesis in bone repair
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89. Overexpressing HPGDS in adipose-derived mesenchymal stem cells reduces inflammatory state and improves wound healing in type 2 diabetic mice
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90. Close-to-native bone repair via tissue-engineered endochondral ossification approaches
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91. Role of Ginkgolides in the Inflammatory Immune Response of Neurological Diseases: A Review of Current Literatures
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92. Mycobacterium tuberculosis Rv1987 protein induces M2 polarization of macrophages through activating the PI3K/Akt1/mTOR signaling pathway
    Shanshan Sha, Yang Shi, Yawei Tang, Liqiu Jia, Xiuyan Han, Yuxin Liu, Xia Li, Yufang Ma · 2021 · Immunology and Cell Biology
93. Surface treatment of 3D printed Cu-bearing Ti alloy scaffolds for application in tissue engineering
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94. Combined Treatment of Monopolar and Bipolar Radiofrequency Increases Skin Elasticity by Decreasing the Accumulation of Advanced Glycated End Products in Aged Animal Skin
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95. Multifunctional nanoprobes for macrophage imaging
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96. Nanomaterials targeting macrophages in sepsis: A promising approach for sepsis management
    Chaoying Song, Jiqian Xu, Chenggang Gao, Wanying Zhang, Xiangzhi Fang, You Shang · 2022 · Frontiers in Immunology
97. Dual delivery of an NF-κB inhibitor and IL-10 through supramolecular hydrogels polarizes macrophages and promotes cardiac repair after myocardial infarction
    Di Wang, Yang Hu, Lili Zhang, Haijian Cai, Yaguang Wang, Ye Zhang · 2023 · Acta Biomaterialia
98. Mobile mechanical signal generator for macrophage polarization
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99. Efficacy of imaging techniques for the diagnosis of apical periodontitis: A systematic review
    Ali Hilmi, Shanon Patel, Kazim Mirza, Johnah C. Galicia · 2023 · International Endodontic Journal
100. Paeoniflorin Coordinates Macrophage Polarization and Mitigates Liver Inflammation and Fibrogenesis by Targeting the NF-κB/HIF-1α Pathway in CCl ₄ -Induced Liver Fibrosis
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