Macrophage plasticity, polarization, and function in health and disease

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Items 701–800 of 1,012

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2. Roles of immune microenvironment in the female reproductive maintenance and regulation: novel insights into the crosstalk of immune cells
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3. Mussel-inspired immunomodulatory and osteoinductive dual-functional hydroxyapatite nanoplatform for promoting bone regeneration
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4. β-Hydroxybutyrate suppresses M1 macrophage polarization through β-hydroxybutyrylation of the STAT1 protein
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5. Macrophage Signaling Pathways in Health and Disease: From Bench to Bedside Applications
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6. Decoding the metabolic dialogue in the tumor microenvironment: from immune suppression to precision cancer therapies
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7. Deficiency in interleukin‐10 production by M2 macrophages in eosinophilic chronic rhinosinusitis with nasal polyps
   Zhichao Wang, Yin Yao, Nan Wang, Jin‐Xin Liu, Jin Ma, Cailing Chen, Yi‐Ke Deng, Meng‐Chen Wang, Liu Yang, Xin‐Hao Zhang et al. · 2018 · International Forum of Allergy & Rhinology
8. HuoXueTongFu Formula Alleviates Intraperitoneal Adhesion by Regulating Macrophage Polarization and the SOCS/JAK2/STAT/PPAR-γ Signalling Pathway
   Min Zhao, Yaoyao Bian, Lili Yang, Yanqi Chen, Yajie Wang, Yan-Ting Ma, Yuqiong Pei, Wenlin Li, Li Zeng · 2019 · Mediators of Inflammation
9. Pulmonary Macrophage and Dendritic Cell Responses to Cryptococcus neoformans
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10. Sirtuin 6: A potential therapeutic target for cardiovascular diseases
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11. Molecular Crosstalk Between Macrophages and Mesenchymal Stromal Cells
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12. Macrophage 3D migration: A potential therapeutic target for inflammation and deleterious progression in diseases
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13. Paraquat promotes acute lung injury in rats by regulating alveolar macrophage polarization through glycolysis
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14. GPP (Composition of Ganoderma lucidum Poly-saccharides and Polyporus umbellatus Poly-saccharides) Enhances Innate Immune Function in Mice
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15. Curcumin: A Dietary Phytochemical for Targeting the Phenotype and Function of Dendritic Cells
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16. Roles and Mechanisms of DNA Methylation in Vascular Aging and Related Diseases
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17. In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy
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18. Effects of CB2 Receptor Modulation on Macrophage Polarization in Pediatric Celiac Disease
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19. Reinventing the human tuberculosis (TB) granuloma: Learning from the cancer field
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20. New Insights into the Understanding of Mechanisms of Radiation-Induced Heart Disease
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21. Macrophage Involvement in Aging-Associated Skeletal Muscle Regeneration
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22. M2 macrophage polarization in systemic sclerosis fibrosis: pathogenic mechanisms and therapeutic effects
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23. Therapeutic Perspectives for Inflammation and Senescence in Osteoarthritis Using Mesenchymal Stem Cells, Mesenchymal Stem Cell-Derived Extracellular Vesicles and Senolytic Agents
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24. Vital roles of m5C RNA modification in cancer and immune cell biology
    Xinyu Gu, Xiao Ma, Chao Chen, Jun Guan, Jing Wang, Shanshan Wu, Haihong Zhu · 2023 · Frontiers in Immunology
25. Anti-Tumor Strategies by Harnessing the Phagocytosis of Macrophages
    Siyuan Li, Yong-Lin Guo, Jia-Wen Tian, He‐Jing Zhang, Rui‐Fang Li, Ping Gong, Zi‐Li Yu · 2023 · Cancers
26. Amplifying cancer treatment: advances in tumor immunotherapy and nanoparticle-based hyperthermia
    Yi Zhang, Zheng Li, Ying Huang, Bingwen Zou, Yong Bo Xu · 2023 · Frontiers in Immunology
27. Targeting Macrophage Polarization for Reinstating Homeostasis following Tissue Damage
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28. The Contribution of Macrophage Plasticity to Inflammatory Arthritis and Their Potential as Therapeutic Targets
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29. Biomimetic scaffolds loaded with mesenchymal stem cells (MSCs) or MSC-derived exosomes for enhanced wound healing
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30. Therapeutic Properties of M2 Macrophages in Chronic Wounds: An Innovative Area of Biomaterial-Assisted M2 Macrophage Targeted Therapy
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31. Decoding the impact of MMP1+ malignant subsets on tumor-immune interactions: insights from single-cell and spatial transcriptomics
    Da-Ming Xu, Ling-Xiao Chen, Ting Xue, Xiaoyu Zhuang, Lichao Wei, Hui Han, Miao Mo · 2025 · Cell Death Discovery
32. Beyond CAR-T Cells: exploring CAR-NK, CAR-M, and CAR-γδ T strategies in solid tumor immunotherapy
    Yingjie Hou, Shihua Hu, Liu Chong, Xin Chen, Yuru Wang, Yi Li, Zhiren Fu, Chunjing Feng, Yanhua Gong, Zichuan Liu et al. · 2025 · Frontiers in Immunology
33. Aloperine suppresses LPS-induced macrophage activation through inhibiting the TLR4/NF-κB pathway
    Yinyin Ye, Yuwei Wang, Yanlang Yang, Liangfei Tao · 2020 · Inflammation Research
34. In utero exposure to low doses of genistein and di‐(2‐ethylhexyl) phthalate (DEHP) alters innate immune cells in neonatal and adult rat testes
    Casandra Walker, Shahrzad Ghazisaeidi, Bérénice Collet, Annie Boisvert, Martine Culty · 2020 · Andrology
35. Prominent Role of Type 2 Immunity in Skin Diseases: Beyond Atopic Dermatitis
    Lina Belmesk, Anastasiya Muntyanu, Emmanuelle Cantin, Zeinah Alhalees, Carolyn S. Jack, Michelle Le, Denis Sasseville, Lisa Iannattone, Moshe Ben‐Shoshan, Ivan V. Litvinov et al. · 2021 · Journal of Cutaneous Medicine and Surgery
36. Goat Milk Exosomes As Natural Nanoparticles for Detecting Inflammatory Processes By Optical Imaging
    Ana Santos‐Coquillat, María Isabel González, Agustín Clemente‐Moragón, Mario González‐Arjona, Virginia Albaladejo‐García, Héctor Peinado, Javier Muñoz, Pilar Ximénez‐Embún, Borja Ibáñez, Eduardo Oliver et al. · 2021 · Small
37. Osteoimmunology and osteonecrosis of the femoral head
    Maoxiao Ma, Zhen Tan, Wuyin Li, Hong Zhang, Youwen Liu, Chen Yue · 2022 · Bone and Joint Research
38. Modulatory Effects of Mushrooms on the Inflammatory Signaling Pathways and Pro-inflammatory Mediators
    Adekunle Babajide Rowaiye, Ifeyomi Wilfred Olobayotan, Olukemi Adejoke Onuh, Doofan Bur, Solomon Oluwasunmibare Oni, Ezinne Janefrances Nwonu, Gordon C. Ibeanu, Angus Nnamdi Oli, T. T. Wood · 2022 · Clinical Complementary Medicine and Pharmacology
39. Role of Transforming Growth Factor Beta in Peripheral Nerve Regeneration: Cellular and Molecular Mechanisms
    Zhiqian Ye, Junbin Wei, Chaoning Zhan, Jin Lin Hou · 2022 · Frontiers in Neuroscience
40. Therapeutic strategies for gastric cancer targeting immune cells: Future directions
    Yan Fei Zhao, Yuansong Bai, Meili Shen, Yapeng Li · 2022 · Frontiers in Immunology
41. Immune System Acts on Orthodontic Tooth Movement: Cellular and Molecular Mechanisms
    Yajun Gao, Qingqing Min, Xingjia Li, Linxiang Liu, Yangyang Lv, Wenjie Xu, Xudong Liu, Hua Wang · 2022 · BioMed Research International
42. Advanced theragnostics for the central nervous system (CNS) and neurological disorders using functional inorganic nanomaterials
    Conklin, Brandon, Conley, Brian M., Hou, Yannan, Chen, Meizi, Lee, Ki-Bum · 2023 · Advanced Drug Delivery Reviews
43. Inflammation driven metabolic regulation and adaptation in macrophages
    Saloni Gupta, Pranita P. Sarangi · 2022 · Clinical Immunology
44. Placental macrophages present distinct polarization pattern and effector functions depending on clinical onset of preeclampsia
    Monika Horvat Merčnik, Carolin Schliefsteiner, Herbert Fluhr, Christian Wadsack · 2023 · Frontiers in Immunology
45. Human umbilical cord mesenchymal stem cell-derived exosomes carrying miR-1827 downregulate SUCNR1 to inhibit macrophage M2 polarization and prevent colorectal liver metastasis
    Jierong Chen, Ziyue Li, Caifeng Yue, Jianhong Ma, Lixue Cao, Jiaxin Lin, Dandan Zhu, Ran An, Jinxin Lai, Yun-Miao Guo et al. · 2023 · APOPTOSIS
46. HIF-1α-Overexpressing Mesenchymal Stem Cells Attenuate Colitis by Regulating M1-like Macrophages Polarization toward M2-like Macrophages
    Wenya Zhu, Qianqian Chen, Yi Li, Jun Wan, Jia Li, Shuai Tang · 2023 · Biomedicines
47. Quercetin Reprograms Immunometabolism of Macrophages via the SIRT1/PGC-1α Signaling Pathway to Ameliorate Lipopolysaccharide-Induced Oxidative Damage
    Jing Peng, Zhen Yang, Hao Li, Baocheng Hao, Dongan Cui, Ruofeng Shang, Yanan Lv, Yu Liu, Wanxia Pu, Hongjuan Zhang et al. · 2023 · International Journal of Molecular Sciences
48. Modulation of macrophage polarization by iron-based nanoparticles
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49. Aerosol pulmonary immune engineering
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50. A potential therapeutic approach for ulcerative colitis: targeted regulation of macrophage polarization through phytochemicals
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51. Mechanisms of lung damage in tuberculosis: implications for chronic obstructive pulmonary disease
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52. 5-aminolevulinate and CHIL3/CHI3L1 treatment amid ischemia aids liver metabolism and reduces ischemia-reperfusion injury
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53. Fibroblast diversity and plasticity in the tumor microenvironment: roles in immunity and relevant therapies
    Yashi Xu, Wei Li, Shitong Lin, Binghan Liu, Peng Wu, Li Li · 2023 · Cell Communication and Signaling
54. Impact of diabetes mellitus on tuberculosis prevention, diagnosis, and treatment from an immunologic perspective
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55. Review of biological activities: A plant of traditional Chinese tonic
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56. Vascular endothelial-derived SPARCL1 exacerbates viral pneumonia through pro-inflammatory macrophage activation
    Gan Zhao, Maria Elena Gentile, Lulu Xue, Christopher V. Cosgriff, Aaron I. Weiner, Stephanie Adams‐Tzivelekidis, Joanna Wong, Xinyuan Li, Sara Kass-Gergi, Nicolas P. Holcomb et al. · 2024 · Nature Communications
57. The role of M1/M2 macrophage polarization in the pathogenesis of obesity-related kidney disease and related pathologies
    Periklis Dousdampanis, Ioanna Aggeletopoulou, Αthanasia Mouzaki · 2025 · Frontiers in Immunology
58. Sedentary behaviour and cardiometabolic health: Integrating the potential underlying molecular health aspects
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59. Inhibition of Ctsk modulates periodontitis with arthritis via downregulation of TLR9 and autophagy
    Wei Wei, Jie Ren, Wuwei Yin, Handong Ding, Qiuyu Lu, Liangyu Tan, Shibing Deng, Jie Liu, Qin Yang, Jiajia Wang et al. · 2019 · Cell Proliferation
60. Phycocyanin Ameliorates Colitis-Associated Colorectal Cancer by Regulating the Gut Microbiota and the IL-17 Signaling Pathway
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61. PlGF Immunological Impact during Pregnancy
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62. The Immuno-Modulation Effect of Macrophage-Derived Extracellular Vesicles in Chronic Inflammatory Diseases
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63. The Emerging Role of Immune Cells and Targeted Therapeutic Strategies in Diabetic Wounds Healing
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64. Pan-cancer analyses and molecular subtypes based on the cancer-associated fibroblast landscape and tumor microenvironment infiltration characterization reveal clinical outcome and immunotherapy response in epithelial ovarian cancer
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65. Immune checkpoint inhibitors in osteosarcoma: A hopeful and challenging future
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66. Natural compounds targeting glycolysis as promising therapeutics for gastric cancer: A review
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67. Rational Design of Bioactive Hydrogels toward Periodontal Delivery: From Pathophysiology to Therapeutic Applications
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68. Oxidized low-density lipoprotein regulates macrophage polarization in atherosclerosis
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69. The effect of Staphylococcus aureus on innate and adaptive immunity and potential immunotherapy for S. aureus-induced osteomyelitis
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70. Immunomodulatory effects of curcumin on macrophage polarization in rheumatoid arthritis
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71. Macrophages as a Source and Target of GDF-15
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72. Disruption of glucose homeostasis by bacterial infection orchestrates host innate immunity through NAD+/NADH balance
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73. Single-cell and spatial transcriptomic profiling revealed niche interactions sustaining growth of endometriotic lesions
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74. Porphyromonas gingivalis inhibits M2 activation of macrophages by suppressing α‐ketoglutarate production in mice
    Shan Yu, Li Ding, D. Liang, Lijun Luo · 2018 · Molecular Oral Microbiology
75. Leukadherin-1-Mediated Activation of CD11b Inhibits LPS-Induced Pro-inflammatory Response in Macrophages and Protects Mice Against Endotoxic Shock by Blocking LPS-TLR4 Interaction
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76. Bergenin as a Novel Urate-Lowering Therapeutic Strategy for Hyperuricemia
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77. Effects of Eltrombopag on In Vitro Macrophage Polarization in Pediatric Immune Thrombocytopenia
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78. Monocyte/Macrophage Lineage Cells From Fetal Erythromyeloid Progenitors Orchestrate Bone Remodeling and Repair
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79. Immunostimulatory effects of the intracellular polysaccharides isolated from liquid culture of Ophiocordyceps sinensis (Ascomycetes) on RAW264.7 cells via the MAPK and PI3K/Akt signaling pathways
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80. Electronic Cigarette Exposure Enhances Lung Inflammatory and Fibrotic Responses in COPD Mice
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81. Recent advancement on development of drug-induced macrophage polarization in control of human diseases
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82. Protective effect of cynaroside on sepsis-induced multiple organ injury through Nrf2/HO-1-dependent macrophage polarization
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83. Notch Signaling in Breast Tumor Microenvironment as Mediator of Drug Resistance
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84. Alveolar macrophages: Achilles’ heel of SARS-CoV-2 infection
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85. Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2
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86. Lamin A/C and the Immune System: One Intermediate Filament, Many Faces
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87. Neutrophil-to-Lymphocyte Ratios Are Closely Associated With the Severity and Course of Non-mild COVID-19
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88. Decidual stromal cells support tolerance at the human foetal-maternal interface by inducing regulatory M2 macrophages and regulatory T-cells
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89. Transcriptomic analysis of asthma and allergic rhinitis reveals CST1 as a biomarker of unified airways
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90. Isoalantolactone protects against ethanol-induced gastric ulcer via alleviating inflammation through regulation of PI3K-Akt signaling pathway and Th17 cell differentiation
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91. Macrophages in aseptic loosening: Characteristics, functions, and mechanisms
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92. Systems pharmacology reveals the mechanism of Astragaloside IV in improving immune activity on cyclophosphamide-induced immunosuppressed mice
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93. Radiotherapy-activated tumor immune microenvironment: Realizing radiotherapy-immunity combination therapy strategies
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94. Inducing in situ M2 macrophage polarization to promote the repair of bone defects via scaffold-mediated sustained delivery of luteolin
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95. Beyond protein synthesis: the emerging role of arginine in poultry nutrition and host-microbe interactions
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96. Insight into the role of macrophages in periodontitis restoration and development
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97. Mechanisms of synovial macrophage polarization in osteoarthritis pathogenesis and their therapeutic implications
    Kun Zhang, Zheng Wang, Jiaqi He, Liuru Lu, Wenshu Wang, Aiwei Yang, Huayi Xie, Linhui Huang, Yuying Huang, Ke Zhang et al. · 2025 · Frontiers in Immunology
98. SerpinB2 inhibits migration and promotes a resolution phase signature in large peritoneal macrophages
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99. Macrophages: First guards in the prevention of cardiovascular diseases
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100. LncRNA FTX represses the progression of non-alcoholic fatty liver disease to hepatocellular carcinoma via regulating the M1/M2 polarization of Kupffer cells
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