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Cited by 355

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

TALL-1 is a novel member of the TNF family that is down-regulated by mitogens

Shu, Hong-Bing, Hu, Wen-Hui, Johnson, Holly·1999·Journal of Leukocyte Biology

Abstract

Members of the tumor necrosis factor (TNF) family play important roles in modulation of immune responses. We describe the identification and cloning of a novel TNF family member that has been designated as TALL-1. TALL-1 is a 285-amino acid type II transmembrane protein. Its carboxy terminus shares ∼35% sequence identity with the recently identified APRIL and ∼20–25% with TNF, FasL, TRAIL, and lymphotoxin-α, suggesting that TALL-1 and APRIL belong to a subfamily of the TNF family of ligands. Northern blot analysis suggests that TALL-1 is expressed abundantly in peripheral blood leukocytes and weakly in spleen but is barely detectable in all other tissues examined. Reverse transcriptase-polymerase chain reaction analysis indicates that TALL-1 is specifically expressed in monocytes and macrophages but is undetectable in T and B lymphocytes. Furthermore, TALL-1 expression is dramatically down-regulated by phorbol myristate acetate/ionomycin. J. Leukoc. Biol. 65: 680–683; 1999.

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Metadata

Authors
Shu, H.-B., Hu, W.-H., & Johnson, H.
Venue
Journal of Leukocyte Biology
Published
1999-05-01
Volume
65
Issue
5
Pages
680-683
ISSN
  • 0741-5400 (ISSN-L)
  • 1938-3673
OpenAlex
W2170489650
Cited by
355
References
13
FWCI
7.29
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: TALL-1 is a novel member of the TNF family that is down-regulated by mitogens. https://app.cochat.ai/papers/10.1002/jlb.65.5.680
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Shu, H.-B., Hu, W.-H., & Johnson, H. (1999). TALL-1 is a novel member of the TNF family that is down-regulated by mitogens. Journal of Leukocyte Biology. https://doi.org/10.1002/jlb.65.5.680

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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