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Cited by 318

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Hyperpolarized 3He MR lung ventilation imaging in asthmatics: Preliminary findings

Altes, Talissa A., Powers, Patrick L., Knight‐Scott, Jack, Rakes, Gary, Platts‐Mills, Thomas A.E., de Lange, Eduard E., Alford, Bennett A., Mugler, John P., Brookeman, James R.·2001·Journal of Magnetic Resonance Imaging

Abstract

Asthma is a disease characterized by chronic inflammation and reversible obstruction of the small airways resulting in impaired pulmonary ventilation. Hyperpolarized 3 He magnetic resonance (MR) lung imaging is a new technology that provides a detailed image of lung ventilation. Hyperpolarized 3 He lung imaging was performed in 10 asthmatics and 10 healthy subjects. Seven asthmatics had ventilation defects distributed throughout the lungs compared with none of the normal subjects. These ventilation defects were more numerous and larger in the two symptomatic asthmatics who had abnormal spirometry. Ventilation defects studied over time demonstrated no change in appearance over 30–60 minutes. One asthmatic subject was studied twice in a three‐week period and had ventilation defects which resolved and appeared in that time. This same subject was studied before and after bronchodilator therapy, and all ventilation defects resolved after therapy. Hyperpolarized 3 He lung imaging can detect the small, reversible ventilation defects that characterize asthma. The ability to visualize lung ventilation offers a direct method of assessing asthmatics and their response to therapy. J. Magn. Reson. Imaging 2001;13:378–384. © 2001 Wiley‐Liss, Inc.

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Metadata

Authors
Altes, T. A., Powers, P. L., Knight‐Scott, J., Rakes, G., Platts‐Mills, T. A. E., de Lange, E. E., Alford, B. A., Mugler, J. P., & Brookeman, J. R.
Venue
Journal of Magnetic Resonance Imaging
Publisher
Wiley
Published
2001-03
Volume
13
Issue
3
Pages
378-384
ISSN
  • 1053-1807 (ISSN-L)
  • 1522-2586
OpenAlex
W1967607641
Cited by
318
References
7
FWCI
12.02
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Hyperpolarized 3He MR lung ventilation imaging in asthmatics: Preliminary findings. https://app.cochat.ai/papers/10.1002/jmri.1054
The paper
Altes, T. A., Powers, P. L., Knight‐Scott, J., Rakes, G., Platts‐Mills, T. A. E., de Lange, E. E., Alford, B. A., Mugler, J. P., & Brookeman, J. R. (2001). Hyperpolarized 3He MR lung ventilation imaging in asthmatics: Preliminary findings. Journal of Magnetic Resonance Imaging. https://doi.org/10.1002/jmri.1054

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