The DOI matches its Crossref record.
MR Imaging with Hyperpolarized 3He Gas
Abstract
Magnetic resonance images of the lungs of a guinea pig have been produced using hyperpolarized helium as the source of the MR signal. The resulting images are not yet sufficiently optimized to reveal fine structural detail within the lung, but the spectacular signal from this normally signal‐deficient organ system offers great promise for eventual in vivo imaging experiments. Fast 2D and 3D GRASS sequences with very small flip angles were employed to conserve the nonrenewable longitudinal magnetization. We discuss various unique features associated with performing MRI with hyperpolarized gases, such as the selection of the noble gas species, polarization technique, and constraints on the MR pulse sequence.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Spin-exchange optical pumping of noble-gas nuclei
Walker, T. G., & Happer, W. (1997) · Reviews of Modern Physics · doi:10.1103/revmodphys.69.629 · Cited by 1,444
Self-citationSamee, S., Altes, T., Powers, P., de Lange, E. E., Knight-Scott, J., Rakes, G., Mugler III, J. P., Ciambotti, J. M., Alford, B. A., Brookeman, J. R., et al. (2003) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2003.1544 · Cited by 324
Hyperpolarized 3He MR lung ventilation imaging in asthmatics: Preliminary findings
Altes, T. A., Powers, P. L., Knight‐Scott, J., Rakes, G., Platts‐Mills, T. A. E., de Lange, E. E., Alford, B. A., Mugler, J. P., & Brookeman, J. R. (2001) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.1054 · Cited by 318
Evaluation of Asthma With Hyperpolarized Helium-3 MRI
de Lange, E. E., Altes, T. A., Patrie, J. T., Gaare, J. D., Knake, J. J., Mugler, J. P., & Platts-Mills, T. A. (2006) · Chest · doi:10.1378/chest.130.4.1055 · Cited by 279
Performance of a 200‐MHz cryogenic RF probe designed for MRI and MRS of the murine brain
Ratering, D., Baltes, C., Nordmeyer‐Massner, J., Marek, D., & Rudin, M. (2008) · Magnetic Resonance in Medicine · doi:10.1002/mrm.21629 · Cited by 91
Metadata
- Authors
- Middleton, H., Black, R. D., Saam, B., Cates, G. D., Cofer, G. P., Guenther, R., Happer, W., Hedlund, L. W., Alan Johnson, G., Juvan, K., & Swartz, J.
- Venue
- Magnetic Resonance in Medicine
- Publisher
- Wiley
- Published
- 1995-02
- Volume
- 33
- Issue
- 2
- Pages
- 271-275
- ISSN
- 0740-3194 (ISSN-L)
- 1522-2594
- OpenAlex
- W2168170401
- Cited by
- 358
- References
- 0
- FWCI
- 17.57
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: MR Imaging with Hyperpolarized 3He Gas. https://app.cochat.ai/papers/10.1002/mrm.1910330219
- The paper
- Middleton, H., Black, R. D., Saam, B., Cates, G. D., Cofer, G. P., Guenther, R., Happer, W., Hedlund, L. W., Alan Johnson, G., Juvan, K., & Swartz, J. (1995). MR Imaging with Hyperpolarized 3He Gas. Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.1910330219
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
