Monoclonal antibody PHF‐1 recognizes tau protein phosphorylated at serine residues 396 and 404

Otvos, L., Feiner, L., Lang, E., Szendrei, G. I., Goedert, M., Lee, V. M‐Y.·1994·Journal of Neuroscience Research

DOI 10.1002/jnr.490390607

Cited by (487)

Items 101–200 of 487

Transgenic Mouse Model of Tauopathies with Glial Pathology and Nervous System Degeneration
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Protein phosphorylation: technologies for the identification of phosphoamino acids
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Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer’s disease
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Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer’s disease
Siddhartha Mondragón‐Rodríguez, Gustavo Basurto‐Islas, Ismael Santa‐María, Raúl Mena, Lester I. Binder, Jesús Ávila, Mark A. Smith, George L. Perry, Francisco García‐Sierra · 2008 · International Journal of Experimental Pathology
Selective Destruction of Stable Microtubules and Axons by Inhibitors of Protein Serine/Threonine Phosphatases in Cultured Human Neurons (NT2N Cells)
Merrick, Sandra E., Trojanowski, John Q., Lee, Virginia M.-Y. · 1997 · The Journal of Neuroscience
Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer’s disease from a ferroptosis perspective
Paul J. Derry, Muralidhar L. Hegde, George R. Jackson, Rakez Kayed, James M. Tour, Ah-Lim Tsai, Thomas A. Kent · 2019 · Progress in Neurobiology
Okadaic-Acid-Induced Inhibition of Protein Phosphatase 2A Produces Activation of Mitogen-Activated Protein Kinases ERK1/2, MEK1/2, and p70 S6, Similar to That in Alzheimer's Disease
Jin-Jing Pei, Cheng‐Xin Gong, Wenlin An, Bengt G. Winblad, Richard F. Cowburn, Inge Grundke, Khalid Iqbal · 2003 · American Journal Of Pathology
Transient increases in intracellular calcium result in prolonged site-selective increases in tau phosphorylation through a glycogen synthase kinase 3β-dependent pathway
Hartigan, Judith A., Johnson, Gail V.W. · 1999 · Journal of Biological Chemistry
Brain Injection of α-Synuclein Induces Multiple Proteinopathies, Gliosis, and a Neuronal Injury Marker
Sacino, Amanda N., Brooks, Mieu, McKinney, Alex B., Thomas, Michael A., Shaw, Gerry, Golde, Todd E., Giasson, Benoit I. · 2014 · The Journal of Neuroscience
Normal and Pathological Tau Proteins as Factors for Microtubule Assembly
André Delacourte, Luc Buée · 1997 · International review of cytology
Convergence of Lewy bodies and neurofibrillary tangles in amygdala neurons of Alzheimer's disease and Lewy body disorders
M. L. Schmidt, John A. Martin, Virginia M.‐Y. Lee, John Q. Trojanowski · 1996 · Acta Neuropathologica
Comparative Analysis of an Improved Thioflavin-S Stain, Gallyas Silver Stain, and Immunohistochemistry for Neurofibrillary Tangle Demonstration on the Same Sections
An-Yang Sun, X. V. Nguyen, G. Bing · 2002 · Journal of Histochemistry and Cytochemistry
Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia
Emmanuel Planel, Alexis Bretteville, Li Liu, László Virág, Angela L. Du, Wai Haung Yu, Dennis W. Dickson, Robert A. Whittington, Karen Duff · 2009 · The FASEB Journal
Palmitic and stearic fatty acids induce Alzheimer-like hyperphosphorylation of tau in primary rat cortical neurons
Sachin P. Patil, Christina Chan · 2005 · Neuroscience Letters
Comparison of the neurofibrillary pathology in Alzheimer’s disease and familial presenile dementia with tangles
Spillantini, M. G., Crowther, R. A., Goedert, M. · 1996 · Acta Neuropathologica
Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice
Leroy, Karelle, Bretteville, Alexis, Schindowski, Katharina, Gilissen, Emmanuel, Authelet, Michèle, De Decker, Robert, Yilmaz, Zehra, Buée, Luc, Brion, Jean-Pierre · 2007 · The American Journal of Pathology
Glycogen Synthase Kinase-3 Plays a Crucial Role in Tau Exon 10 Splicing and Intranuclear Distribution of SC35
Félix Hernández, Mar Pérez, José J. Lucas, Ana M. Mata, Ratan V. Bhat, Jesús Ávila · 2004 · Journal of Biological Chemistry
E46K Human α-Synuclein Transgenic Mice Develop Lewy-like and Tau Pathology Associated with Age-dependent, Detrimental Motor Impairment
Kristel L. Emmer, Elisa A. Waxman, Jason P. Covy, Benoit I. Giasson · 2011 · Journal of Biological Chemistry
Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: effects on axonal viability
Gasparini, Laura, Anthony Crowther, R., Martin, Keith R., Berg, Nicola, Coleman, Michael, Goedert, Michel, Spillantini, Maria Grazia · 2011 · Neurobiology of Aging
Tau Aggregation and Toxicity in a Cell Culture Model of Tauopathy
Bhaswati Bandyopadhyay, Guibin Li, Haishan Yin, Jeff Kuret · 2007 · Journal of Biological Chemistry
Propofol Directly Increases Tau Phosphorylation
Robert A. Whittington, László Virág, François Marcouiller, Marie-Amélie Papon, Noura B. El Khoury, Carl Julien, Françoise Morin, Charles W. Emala, Emmanuel Planel · 2011 · PLoS ONE
Expression of A152T human tau causes age‐dependent neuronal dysfunction and loss in transgenic mice
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Dephosphorylation of Tau by Protein Phosphatase 5
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Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein
Jochen Eidenmüller, Thomas Fath, Thorsten Maas, Madeline Pool, Estelle Sontag, Roland Brandt · 2001 · Biochemical Journal
Distinct FTDP-17 Missense Mutations in Tau Produce Tau Aggregates and Other Pathological Phenotypes in Transfected CHO Cells
Vanessa Vogelsberg-Ragaglia, JENNIFER S. BRUCE, Christiane Richter‐Landsberg, Bin Zhang, Ming Hong, John Q. Trojanowski, Virginia M.‐Y. Lee · 2000 · Molecular Biology of the Cell
NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies
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Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations
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Acetylated Tau Neuropathology in Sporadic and Hereditary Tauopathies
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Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy
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Involvement of astroglial ceramide in palmitic acid‐induced Alzheimer‐like changes in primary neurons
Sachin P. Patil, Joseph Melrose, Christina Chan · 2007 · European Journal of Neuroscience
Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer’s disease model
Polydoro, Manuela, Dzhala, Volodymyr I., Pooler, Amy M., Nicholls, Samantha B., McKinney, A. Patrick, Sanchez, Laura, Pitstick, Rose, Carlson, George A., Staley, Kevin J., Spires-Jones, Tara L. et al. · 2014 · Acta Neuropathologica
Grape Derived Polyphenols Attenuate Tau Neuropathology in a Mouse Model of Alzheimer's Disease
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Calcium-mediated Transient Phosphorylation of Tau and Amyloid Precursor Protein Followed by Intraneuronal Amyloid-β Accumulation
Nathalie Pierrot, Susana Ferrão Santos, Christine Feyt, Marina Morel, Jean‐Pierre Brion, Jean Noël Octave · 2006 · Journal of Biological Chemistry
Aβ-induced acceleration of Alzheimer-related τ-pathology spreading and its association with prion protein
Gomes, Luis Aragão, Hipp, Silvia Andrea, Rijal Upadhaya, Ajeet, Balakrishnan, Karthikeyan, Ospitalieri, Simona, Koper, Marta J., Largo-Barrientos, Pablo, Uytterhoeven, Valerie, Reichwald, Julia, Rabe, Sabine et al. · 2019 · Acta Neuropathologica
Regulation of Glycogen Synthase Kinase 3β and Downstream Wnt Signaling by Axin
Chester M. Hedgepeth, Matthew A. Deardorff, Kathleen Rankin, Peter S. Klein · 1999 · Molecular and Cellular Biology
Tau Phosphorylation by GSK3 in Different Conditions
Jesús Ávila, Gonzalo León‐Espinosa, Esther García, Vega García‐Escudero, Félix Hernández, Javier DeFelipe · 2012 · International Journal of Alzheimer s Disease
NMR Analysis of a Tau Phosphorylation Pattern
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Structural and Functional Implications of Tau Hyperphosphorylation: Information from Phosphorylation-Mimicking Mutated Tau Proteins
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Glycogen Synthase Kinase 3β Induces Caspase-cleaved Tau Aggregation in Situ
Jae‐Hyeon Cho, Gail V.W. Johnson · 2004 · Journal of Biological Chemistry
Concurrent alterations of O‐GlcNAcylation and phosphorylation of tau in mouse brains during fasting
Xu Li, LU Fen, Jian‐Zhi Wang, Cheng‐Xin Gong · 2006 · European Journal of Neuroscience
Tau as a therapeutic target in neurodegenerative disease
Diana S. Himmelstein, Sarah Ward, Jody K. Lancia, Kristina R. Patterson, Lester I. Binder · 2012 · Pharmacology & Therapeutics
Argyrophilic grain disease: widespread hyperphosphorylation of tau protein in limbic neurons
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Tau Protein and the Neurofibrillary Pathology of Alzheimer's Disease
Michel Goedert · 1996 · Annals of the New York Academy of Sciences
Site-specific Phosphorylation and Caspase Cleavage Differentially Impact Tau-Microtubule Interactions and Tau Aggregation
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Alpha‐Synuclein induces hyperphosphorylation of Tau in the MPTP model of Parkinsonism
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Characteristics of TBS-Extractable Hyperphosphorylated Tau Species: Aggregation Intermediates in rTg4510 Mouse Brain
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Dynamic Regulation of Expression and Phosphorylation of Tau by Fibroblast Growth Factor-2 In Neural Progenitor Cells from Adult Rat Hippocampus
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Tau Accumulation, Altered Phosphorylation, and Missorting Promote Neurodegeneration in Glaucoma
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Tau Phosphorylated at Tyrosine 394 is Found in Alzheimer's Disease Tangles and can be a Product of the Abl-Related Kinase, Arg
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Inhibition of PP‐2A upregulates CaMKII in rat forebrain and induces hyperphosphorylation of tau at Ser 262/356
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Lithium treatment arrests the development of neurofibrillary tangles in mutant tau transgenic mice with advanced neurofibrillary pathology.
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Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A
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Filamentous Tau Pathology in Nerve Cells, Astrocytes, and Oligodendrocytes of Aged Baboons
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Activation of a PP2A-like phosphatase and dephosphorylation of τ protein characterize onset of the execution phase of apoptosis
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Tau phosphorylation regulates the interaction between BIN1’s SH3 domain and Tau’s proline-rich domain
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White matter imaging helps dissociate tau from TDP-43 in frontotemporal lobar degeneration
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Microtubule-Affinity Regulating Kinase (MARK) Is Tightly Associated with Neurofibrillary Tangles in Alzheimer Brain: A Fluorescence Resonance Energy Transfer Study
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Inhibition of JNK by a Peptide Inhibitor Reduces Traumatic Brain Injury–Induced Tauopathy in Transgenic Mice
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The Low Density Lipoprotein Receptor-related Protein 6 Interacts with Glycogen Synthase Kinase 3 and Attenuates Activity
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Soluble tau Species, Not Neurofibrillary Aggregates, Disrupt Neural System Integration in a tau Transgenic Model
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Characterisation of cytoskeletal abnormalities in mice transgenic for wild-type human tau and familial Alzheimer's disease mutants of APP and presenilin-1
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Pathological conformations involving the amino terminus of tau occur early in Alzheimer's disease and are differentially detected by monoclonal antibodies
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Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy
Zapporah T. Young, Jennifer N. Rauch, Victoria A. Assimon, Umesh K. Jinwal, Misol Ahn, Xiaokai Li, Bryan M. Dunyak, Atta Ahmad, George A. Carlson, Sharan R. Srinivasan et al. · 2016 · Cell chemical biology
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GSK3β phosphorylation catalyzes the aggregation of tau into Alzheimer’s disease-like filaments
Chakraborty, Pijush, Ibáñez de Opakua, Alain, Purslow, Jeffrey A., Fromm, Simon A., Chatterjee, Debdeep, Zachrdla, Milan, Zhuang, Shannon, Puri, Sambhavi, Wolozin, Benjamin, Zweckstetter, Markus · 2024 · Proceedings of the National Academy of Sciences
Age-related progression of tau pathology in brains of baboons
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N-Terminal Fragments of Tau Inhibit Full-Length Tau Polymerization in Vitro
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The Peptidyl Prolyl cis/trans-Isomerase Pin1 Recognizes the Phospho-Thr212-Pro213 Site on Tau
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Inhibitors of protein phosphatase-2A from human brain structures, immunocytological localization and activities towards dephosphorylation of the Alzheimer type hyperphosphorylated tau
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Increased misfolding and truncation of tau in APP/PS1/tau transgenic mice compared to mutant tau mice
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Tau hyperphosphorylation and P-CREB reduction are involved in acrylamide-induced spatial memory impairment: Suppression by curcumin
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Coexpression of Human cdk5 and Its Activator p35 with Human Protein Tau in Neurons in Brain of Triple Transgenic Mice
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Attenuated Neurodegenerative Disease Phenotype in Tau Transgenic Mouse Lacking Neurofilaments
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Tau Protein Is Cross-Linked by Transglutaminase in P301L Tau Transgenic Mice
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