The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
Mechanisms of tendon injury and repair
Open accessAbstract
Tendon disorders are common and lead to significant disability, pain, healthcare cost, and lost productivity. A wide range of injury mechanisms exist leading to tendinopathy or tendon rupture. Tears can occur in healthy tendons that are acutely overloaded (e.g., during a high speed or high impact event) or lacerated (e.g., a knife injury). Tendinitis or tendinosis can occur in tendons exposed to overuse conditions (e.g., an elite swimmer's training regimen) or intrinsic tissue degeneration (e.g., age‐related degeneration). The healing potential of a torn or pathologic tendon varies depending on anatomic location (e.g., Achilles vs. rotator cuff) and local environment (e.g., intrasynovial vs. extrasynovial). Although healing occurs to varying degrees, in general healing of repaired tendons follows the typical wound healing course, including an early inflammatory phase, followed by proliferative and remodeling phases. Numerous treatment approaches have been attempted to improve tendon healing, including growth factor‐ and cell‐based therapies and rehabilitation protocols. This review will describe the current state of knowledge of injury and repair of the three most common tendinopathies—flexor tendon lacerations, Achilles tendon rupture, and rotator cuff disorders—with a particular focus on the use of animal models for understanding tendon healing. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:832–839, 2015.
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Tendon and Ligament Healing and Current Approaches to Tendon and Ligament Regeneration
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Battling adhesions: from understanding to prevention
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Metadata
- Authors
- Thomopoulos, S., Parks, W. C., Rifkin, D. B., & Derwin, K. A.
- Venue
- Journal of Orthopaedic Research
- Publisher
- Wiley
- Published
- 2015-03-02
- Volume
- 33
- Issue
- 6
- Pages
- 832-839
- ISSN
- 0736-0266 (ISSN-L)
- 1554-527X
- OpenAlex
- W1516501789
- Cited by
- 564
- References
- 54
- FWCI
- 29.85
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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