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Cited by 1Clinical Nutrition and GastroenterologyDietetics, Nutrition, and EducationHealth Sciences Research and Education

Highlights in the clinical nutrition literature: A critical appraisal of current research

Open access
Stoppe, Christian, Elke, Gunnar, Silvstre, Simone Chaves de Miranda, Kappus, Matthew·2024·Journal of Parenteral and Enteral Nutrition
DOI 10.1002/jpen.2599
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Abstract

Within the American Society for Parenteral and Enteral Nutrition (ASPEN), the Physician Engagement Committee (PEC) was created in 2017 by the ASPEN Board of Directors with the goal of growing the physician community both nationally and internationally. The PEC meets each month throughout the year to develop educational and research initiatives. In 2022, the PEC began an initiative to systematically review and evaluate practice‐changing literature annually with the overall aim to highlight these studies at the annual ASPEN conferences and to critically discuss the potential clinical implications. The objective of the held meeting session was to present identified key papers in the fields of critical care medicine, gastroenterology and hepatology, and adult internal medicine that were published in 2022, which would complement the knowledge of the pathogenesis, diagnosis, and management of nutrition topics as well as to identify areas of future research. Overall, several large‐scale randomized controlled studies were identified in each of these sections, with practice‐changing major results. This manuscript summarizes the information that was presented and the discussions that followed.

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  • The inclusion of renal function and micronutrient biomarkers aligns with ESPEN and ASPEN recommendations that advocate for multidimensional biochemical panels in clinical nutrition practice.

    “The inclusion of renal function and micronutrient biomarkers aligns with current European Society of Clinical Nutrition and Metabolism (ESPEN) [153] and American Society for Parenteral and Enteral Nutrition (ASPEN) [154] recommendations that advocate for multidimensional biochemical panels in clinical nutrition practice.”

    From The Seven Methods for the Evaluation of Nutritional Status—ABCDEFG: Narrative Review (2026) · cites this paper as [154]

    The Conclusion (page unavailable) highlights the importance of micronutrient and metabolomic data for certain patients, and the critical-care discussion says biomarkers may help monitor nutrition support. Neither passage states an ASPEN recommendation for a multidimensional biochemical panel that includes renal-function and micronutrient biomarkers. Searches for those panel components and for biochemical-monitoring recommendations found no such passage in our copy. (LLM, conf=0.72)

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Research works printed but not linked: 28

  1. Cederholm T, Barazzoni R, Austin P, et al. ESPEN guidelines on definitions and terminology of clinical nutrition. Clin Nutr. 2017;36(1): 49-64.
  2. Dresen E, Notz Q, Menger J, et al. What the clinician needs to know about medical nutrition therapy in critically ill patients in 2023: a narrative review. Nutr Clin Pract. 2023;38(3):479-498.
  3. Agarwal A, Basmaji J, Fernando SM, et al. Administration of parenteral vitamin C in patients with severe infection: protocol for a systematic review and meta-analysis. JMIR Res Protoc. 2022;11(1):e33989.
  4. Lee ZY, Ortiz-Reyes L, Lew CCH, et al. Intravenous vitamin C monotherapy in critically ill patients: a systematic review and meta- analysis of randomized controlled trials with trial sequential analysis. Ann Intensive Care. 2023;13(1):14.
  5. Ortiz-Reyes L, Lee ZY, Chin Han Lew C, et al. The efficacy of glutamine supplementation in severe adult burn patients: a systematic review with trial sequential meta-analysis. Crit Care Med. 2023;51(8):1086-1095.
  6. Heyland DK, Wibbenmeyer L, Pollack JA, et al. A randomized trial of enteral glutamine for treatment of burn injuries. N Engl J Med. 2022;387(11):1001-1010.
  7. Stoppe C, McDonald B, Meybohm P, et al. Effect of high-dose selenium on postoperative organ dysfunction and mortality in cardiac surgery patients: the SUSTAIN CSX randomized clinical trial. JAMA Surg. 2023;158(3):235-244.
  8. McDonald VM, Fingleton J, Agusti A, et al. Treatable traits: a new paradigm for 21st century management of chronic airway diseases: Treatable Traits Down Under International Workshop report. Eur Respir J. 2019;53(5):1802058.
  9. Stoppe C, Preiser JC, de Backer D, Elke G. Intravenous vitamin C in adults with sepsis in the intensive care unit: still LOV'IT? Crit Care. 2022;26(1):230.
  10. Matejovic M, Huet O, Dams K, et al. Medical nutrition therapy and clinical outcomes in critically ill adults: a European multinational, prospective observational cohort study (EuroPN). Crit Care. 2022;26(1):143.
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  14. Lee ZY, Lew CCH, Berger MM, Hill A, Stoppe C. Nutrition during the acute phase of critical illness: discussions on NUTRIREA-3. Lancet Respir Med. 2023;11(7):e62-e63.
  15. Patel JJ, Rice TW, Mundi MS, Stoppe C, McClave SA. Nutrition dose in the early acute phase of critical illness: finding the sweet spot and heeding the lessons from the NUTRIREA trials. JPEN J Parenter Enteral Nutr. 2023;47(7):859-865.
  16. Agha M, Agha R. The rising prevalence of obesity: part A: impact on public health. Int J Surg Oncol (N Y). 2017;2(7):e17.
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  18. Wand H, Moodley J, Reddy T, Vujovich-Dunn C, Naidoo S. Quantifying impact of obesity on cardiometabolic comorbidities and public health implications: insights from South Africa. Obes Res Clin Pract. 2023;17(2):122-129.
  19. Ward ZJ, Bleich SN, Cradock AL, et al. Projected U.S. state-level prevalence of adult obesity and severe obesity. N Engl J Med. 2019;381(25):2440-2450.
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Authors
Stoppe, C., Elke, G., Silvstre, S. C. D. M., & Kappus, M.
Affiliations
  • Universitätsklinikum Würzburg (DE)
  • University Hospital Schleswig-Holstein (DE)
  • Department of Nutrology Hospital Felicio Rocho Belo Horizonte Brazil
  • Duke University (US)
Corresponding author
Kappus, Matthew
ORCID
Venue
Journal of Parenteral and Enteral Nutrition
Publisher
Wiley
Published
2024-02-04
Volume
48
Issue
4
Pages
377-388
ISSN
  • 0148-6071 (ISSN-L)
  • 1941-2444
DOI
10.1002/jpen.2599
OpenAlex
W4391521896
Cited by
1
References
9
Citations by year
2026: 1
FWCI
0.06
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Parenteral and Enteral Nutrition (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
  • Health Sciences › Health Professions › Health Information Management › Dietetics, Nutrition, and Education
  • Health Sciences › Health Professions › General Health Professions › Health Sciences Research and Education
Keywords
clinical nutrition, critical care nutrition, randomized controlled trials
MeSH terms
Critical Care, Enteral Nutrition, Gastroenterology, Humans, Parenteral Nutrition, Societies, Medical, Biomedical Research

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