The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Antioxidant properties, radical scavenging activity and biomolecule protection capacity of flavonoid naringenin and its glycoside naringin: a comparative study
Abstract
BACKGROUND: This study was designed to evaluate and compare antioxidant capacity and radical scavenging activity of naringin and its aglycone by different in vitro assays. The effects of flavanones on lipid peroxidation, glutathione (GSH) oxidation and DNA cleavage were also assessed. RESULTS: The results showed that naringenin exhibited higher antioxidant capacity and hydroxyl and superoxide radical scavenger efficiency than naringin. Our results evidenced that glycosylation attenuated the efficiency in inhibiting the enzyme xanthine oxidase and the aglycone could act like a more active chelator of metallic ions than the glycoside. Additionally, naringenin showed a greater effectiveness in the protection against oxidative damage to lipids in a dose‐dependent manner. Both flavanones were equally effective in reducing DNA damage. However, they show no protective effect on oxidation of GSH. CONCLUSION: The data obtained support the importance of characterizing the ratio naringin/naringenin in foods when they are evaluated for their health benefits. Copyright © 2010 Society of Chemical Industry
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Alam, M. A., Subhan, N., Rahman, M. M., Uddin, S. J., Reza, H. M., & Sarker, S. D. (2014) · Advances in Nutrition · doi:10.3945/an.113.005603 · Cited by 788
The Role of Polyphenols in Abiotic Stress Response: The Influence of Molecular Structure
Šamec, D., Karalija, E., Šola, I., Vujčić Bok, V., & Salopek-Sondi, B. (2021) · Plants · doi:10.3390/plants10010118 · Cited by 686
Flavonoids as prospective compounds for anti-cancer therapy
Ravishankar, D., Rajora, A. K., Greco, F., & Osborn, H. M. I. (2013) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2013.10.004 · Cited by 572
Beneficial Effects of Citrus Flavonoids on Cardiovascular and Metabolic Health
Mahmoud, A. M., Hernández Bautista, R. J., Sandhu, M. A., & Hussein, O. E. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/5484138 · Cited by 298
Rudrapal, M., Rakshit, G., Singh, R. P., Garse, S., Khan, J., & Chakraborty, S. (2024) · Antioxidants · doi:10.3390/antiox13040429 · Cited by 259
Metadata
- Authors
- Cavia‐Saiz, M., Busto, M. D., Pilar‐Izquierdo, M. C., Ortega, N., Perez‐Mateos, M., & Muñiz, P.
- Venue
- Journal of the Science of Food and Agriculture
- Publisher
- Wiley
- Published
- 2010-03-29
- Volume
- 90
- Issue
- 7
- Pages
- 1238-1244
- ISSN
- 0022-5142 (ISSN-L)
- 1097-0010
- OpenAlex
- W2157768596
- Cited by
- 441
- References
- 33
- FWCI
- 4.95
- Type
- journal article
- Language
- en
- Open access
- closed
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- Cavia‐Saiz, M., Busto, M. D., Pilar‐Izquierdo, M. C., Ortega, N., Perez‐Mateos, M., & Muñiz, P. (2010). Antioxidant properties, radical scavenging activity and biomolecule protection capacity of flavonoid naringenin and its glycoside naringin: a comparative study. Journal of the Science of Food and Agriculture. https://doi.org/10.1002/jsfa.3959
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