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Applications of silica‐based monolithic HPLC columns

Cabrera, Karin·2004·Journal of Separation Science

Abstract

The recent invention and successive commercial introduction of monolithic silica columns has motivated many scientists from both academia and industry to study their use in HPLC. The first paper on monolithic silica columns appeared in 1996. Currently about 200 papers have been published relating to applications and characterization of monolithic silica columns, including monolithic capillaries. This review attempts to give an overview covering various aspects of this new column type in the field of high throughput analysis of drugs and metabolites, chiral separations, analysis of pollutants and food‐relevant compounds, as well as in bioanalytical separations such as in proteomics. Some of the applications are described in greater detail. The numerous publications dealing with the physicochemical and chromatographic characterization of monolithic silica columns are briefly summarized.

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Metadata

Authors
Cabrera, K.
Venue
Journal of Separation Science
Publisher
Wiley
Published
2004-07
Volume
27
Issue
10-11
Pages
843-852
ISSN
  • 1615-9306 (ISSN-L)
  • 1615-9314
OpenAlex
W2080038602
Cited by
423
References
0
FWCI
16.46
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Applications of silica‐based monolithic HPLC columns. https://app.cochat.ai/papers/10.1002/jssc.200401827
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Cabrera, K. (2004). Applications of silica‐based monolithic HPLC columns. Journal of Separation Science. https://doi.org/10.1002/jssc.200401827

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.