The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Fast analysis in liquid chromatography using small particle size and high pressure
Open accessAbstract
In order to enhance chromatographic performances in terms of efficiency and rapidity, LC has recently evolved in the development of short columns packed with small particles (sub‐2 μm) working at high pressures (>400 bar). This approach has been described 30 years ago according to the fundamental chromatographic equations. However, systems and columns compatible with such high pressures have been introduced in the market in 2004 only. Advantages of small particles working at high pressure will be discussed in terms of sensitivity, efficiency, resolution, and analysis time. Potential problems encountered with high pressure in terms of frictional heating and solvent compressibility will also be discussed even if systems working at a maximum pressure of 1000 bar are not influenced by these parameters and give reliable and reproducible results. Several applications will highlight the potential and interest of this new technology.
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Cites
Octadecylsilylated Porous Silica Rods as Separation Media for Reversed-Phase Liquid Chromatography
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Advantages of application of UPLC in pharmaceutical analysis
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Applications of silica‐based monolithic HPLC columns
Cabrera, K. (2004) · Journal of Separation Science · doi:10.1002/jssc.200401827 · Cited by 423
Wilson, I. D., Nicholson, J. K., Castro-Perez, J., Granger, J. H., Johnson, K. A., Smith, B. W., & Plumb, R. S. (2005) · Journal of Proteome Research · doi:10.1021/pr049769r · Cited by 420
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Cited by
Chromatographic Separation Techniques and Data Handling Methods for Herbal Fingerprints: A Review
Tistaert, C., Dejaegher, B., & Heyden, Y. V. (2011) · Analytica Chimica Acta · doi:10.1016/j.aca.2011.02.023 · Cited by 341
Metadata
- Authors
- Nguyen, D. T. ‐., Guillarme, D., Rudaz, S., & Veuthey, J.
- Venue
- Journal of Separation Science
- Publisher
- Wiley
- Published
- 2006-08
- Volume
- 29
- Issue
- 12
- Pages
- 1836-1848
- ISSN
- 1615-9306 (ISSN-L)
- 1615-9314
- OpenAlex
- W1990112228
- Cited by
- 337
- References
- 41
- FWCI
- 10.21
- Type
- journal article
- Language
- en
- Open access
- bronze
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