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Integrated optical devices for lab‐on‐a‐chip biosensing applications
Open accessAbstract
The application of portable, easy‐to‐use and highly sensitive lab‐on‐a‐chip biosensing devices for real‐time diagnosis could offer significant advantages over current analytical methods. Integrated optics‐based biosensors have become the most suitable technology for lab‐on‐chip integration due to their ability for miniaturization, their extreme sensitivity, robustness, reliability, and their potential for multiplexing and mass production at low cost. This review provides an extended overview of the state‐of‐the‐art in integrated photonic biosensors technology including interferometers, grating couplers, microring resonators, photonic crystals and other novel nanophotonic transducers. Particular emphasis has been placed on describing their real biosensing applications and wherever possible a comparison of the sensing performances between each type of device is included. The way towards achieving operative lab‐on‐a‐chip platform incorporating the photonic biosensors is also reviewed. Concluding remarks regarding the future prospects and potential impact of this technology are also provided.
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Cites
Ultra-high-Q toroid microcavity on a chip
Armani, D. K., Kippenberg, T. J., Spillane, S. M., & Vahala, K. J. (2003) · Nature · doi:10.1038/nature01371 · Cited by 2,214
Cited by
Optical waveguides in crystalline dielectric materials produced by femtosecond‐laser micromachining
Chen, F., & de Aldana, J. R. V. (2014) · Laser & Photonics Reviews · doi:10.1002/lpor.201300025 · Cited by 688
Ryckeboer, E., Gassenq, A., Muneeb, M., Hattasan, N., Pathak, S., Cerutti, L., Rodriguez, J. B., Tournié, E., Bogaerts, W., Baets, R., et al. (2013) · Optics Express · doi:10.1364/oe.21.006101 · Cited by 106
Pillai, S., Upadhyay, A., Sayson, D., Nguyen, B. H., & Tran, S. D. (2021) · Molecules · doi:10.3390/molecules27010165 · Cited by 95
Patko, D., Mártonfalvi, Z., Kovacs, B., Vonderviszt, F., Kellermayer, M., & Horvath, R. (2014) · Sensors and Actuators B: Chemical · doi:10.1016/j.snb.2014.01.107 · Cited by 74
Metadata
- Authors
- Estevez, M. C., Alvarez, M., & Lechuga, L. M.
- Venue
- Laser & Photonics Reviews
- Publisher
- Wiley
- Published
- 2011-09-26
- Volume
- 6
- Issue
- 4
- Pages
- 463-487
- ISSN
- 1863-8880 (ISSN-L)
- 1863-8899
- OpenAlex
- W2094474867
- Cited by
- 617
- References
- 1
- FWCI
- 12.48
- Type
- journal article
- Language
- en
- Open access
- green
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- Estevez, M. C., Alvarez, M., & Lechuga, L. M. (2012). Integrated optical devices for lab‐on‐a‐chip biosensing applications. Laser & Photonics Reviews. https://doi.org/10.1002/lpor.201100025
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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