The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Uptake Mechanism of Oppositely Charged Fluorescent Nanoparticles in HeLa Cells
Abstract
The endocytotic mechanisms involved in the uptake of charged polystyrene nanoparticles into HeLa cells were investigated. Uptake experiments were done in the presence or absence of drugs known to inhibit various factors in endocytosis. Independent of the particle charge, endocytosis is highly dependent on dynamin, F‐actin, and tyrosine‐specific protein kinases, which suggests a dynamin‐dependent and lipid raft‐dependent mechanism. However, cholesterol depletion did not hinder particle uptake. Regarding positively charged particles, macropinocytosis, the microtubule network, and cyclooxygenases are also involved. The clathrin‐dependent pathway plays a minor role. magnified image
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Cites
Transcytosis: Crossing Cellular Barriers
TUMA, P. L., & HUBBARD, A. L. (2003) · Physiological Reviews · doi:10.1152/physrev.00001.2003 · Cited by 681
Cited by
Biomolecular coronas provide the biological identity of nanosized materials
Monopoli, M. P., Åberg, C., Salvati, A., & Dawson, K. A. (2012) · Nature Nanotechnology · doi:10.1038/nnano.2012.207 · Cited by 3,017
Insight into Cellular Uptake and Intracellular Trafficking of Nanoparticles
Foroozandeh, P., & Aziz, A. A. (2018) · Nanoscale Research Letters · doi:10.1186/s11671-018-2728-6 · Cited by 1,377
Duan, X., & Li, Y. (2013) · Small · doi:10.1002/smll.201201390 · Cited by 926
Nanoparticle Adhesion to the Cell Membrane and Its Effect on Nanoparticle Uptake Efficiency
Lesniak, A., Salvati, A., Santos-Martinez, M. J., Radomski, M. W., Dawson, K. A., & Åberg, C. (2013) · Journal of the American Chemical Society · doi:10.1021/ja309812z · Cited by 852
Berg, J. M., Romoser, A., Banerjee, N., Zebda, R., & Sayes, C. M. (2009) · Nanotoxicology · doi:10.3109/17435390903276941 · Cited by 364
Metadata
- Authors
- Dausend, J., Musyanovych, A., Dass, M., Walther, P., Schrezenmeier, H., Landfester, K., & Mailänder, V.
- Venue
- Macromolecular Bioscience
- Publisher
- Wiley
- Published
- 2008-11-25
- Volume
- 8
- Issue
- 12
- Pages
- 1135-1143
- ISSN
- 1616-5187 (ISSN-L)
- 1616-5195
- OpenAlex
- W2154482941
- Cited by
- 297
- References
- 1
- FWCI
- 6.96
- Type
- journal article
- Language
- en
- Open access
- closed
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- Dausend, J., Musyanovych, A., Dass, M., Walther, P., Schrezenmeier, H., Landfester, K., & Mailänder, V. (2008). Uptake Mechanism of Oppositely Charged Fluorescent Nanoparticles in HeLa Cells. Macromolecular Bioscience. https://doi.org/10.1002/mabi.200800123
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
