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Electrospun Non‐Woven Nanofibrous Hybrid Mats Based on Chitosan and PLA for Wound‐Dressing Applications
Abstract
Continuous defect‐free nanofibers containing chitosan (Ch) or quaternized chitosan (QCh) were successfully prepared by one‐step electrospinning of Ch or QCh solutions mixed with poly[(L‐lactide)‐co‐(d,l‐lactide)] in common solvent. XPS revealed the surface chemical composition of the bicomponent electrospun mats. Crosslinked Ch‐ and QCh‐containing nanofibers exhibited higher kill rates against bacteria S. aureus and E. coli than the corresponding solvent‐cast films. SEM observations showed that hybrid mats were very effective in suppressing the adhesion of pathogenic bacteria S. aureus. The hybrid nanofibers are promising for wound‐healing applications. magnified image
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Cited by
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Ulery, B. D., Nair, L. S., & Laurencin, C. T. (2011) · Journal of Polymer Science Part B: Polymer Physics · doi:10.1002/polb.22259 · Cited by 2,206
25th Anniversary Article: Rational Design and Applications of Hydrogels in Regenerative Medicine
Annabi, N., Tamayol, A., Uquillas, J. A., Akbari, M., Bertassoni, L. E., Cha, C., Camci‐Unal, G., Dokmeci, M. R., Peppas, N. A., & Khademhosseini, A. (2014) · Advanced Materials · doi:10.1002/adma.201303233 · Cited by 1,409
Hydrolytic degradation of polylactic acid (PLA) and its composites
Elsawy, M. A., Kim, K.-H., Park, J.-W., & Deep, A. (2017) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2017.05.143 · Cited by 988
A review on wound dressings with an emphasis on electrospun nanofibrous polymeric bandages
Zahedi, P., Rezaeian, I., Ranaei‐Siadat, S., Jafari, S., & Supaphol, P. (2010) · Polymers for Advanced Technologies · doi:10.1002/pat.1625 · Cited by 906
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Metadata
- Authors
- Ignatova, M., Manolova, N., Markova, N., & Rashkov, I.
- Venue
- Macromolecular Bioscience
- Publisher
- Wiley
- Published
- 2008-12-22
- Volume
- 9
- Issue
- 1
- Pages
- 102-111
- ISSN
- 1616-5187 (ISSN-L)
- 1616-5195
- OpenAlex
- W1968578817
- Cited by
- 198
- References
- 0
- FWCI
- 3.72
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ignatova, M., Manolova, N., Markova, N., & Rashkov, I. (2009). Electrospun Non‐Woven Nanofibrous Hybrid Mats Based on Chitosan and PLA for Wound‐Dressing Applications. Macromolecular Bioscience. https://doi.org/10.1002/mabi.200800189
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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