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Cited by 2,206biodegradable polymer synthesis and propertiesHydrogels: synthesis, properties, applicationsAdvanced Drug Delivery Systems

Biomedical applications of biodegradable polymers

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Ulery, Bret D., Nair, Lakshmi S., Laurencin, Cato T.·2011·Journal of Polymer Science Part B: Polymer Physics
DOI 10.1002/polb.22259PMC PMC3136871
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Abstract

Utilization of polymers as biomaterials has greatly impacted the advancement of modern medicine. Specifically, polymeric biomaterials that are biodegradable provide the significant advantage of being able to be broken down and removed after they have served their function. Applications are wide ranging with degradable polymers being used clinically as surgical sutures and implants. To fit functional demand, materials with desired physical, chemical, biological, biomechanical, and degradation properties must be selected. Fortunately, a wide range of natural and synthetic degradable polymers has been investigated for biomedical applications with novel materials constantly being developed to meet new challenges. This review summarizes the most recent advances in the field over the past 4 years, specifically highlighting new and interesting discoveries in tissue engineering and drug delivery applications. © 2011 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys, 2011

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  • These polymers are broken down without the use of any enzymes by straightforward hydrolysis of the ester bonds in their chains.

    “These polymers are broken down without the use of any enzymes by straightforward hydrolysis of the ester bonds in their chains [86].”

    From Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review (2023) · cites this paper as [86]

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Authors
Ulery, B. D., Nair, L. S., & Laurencin, C. T.
Affiliations
  • UConn Health (US)
  • University of Connecticut (US)
Corresponding author
Laurencin, Cato T.
ORCID
Venue
Journal of Polymer Science Part B: Polymer Physics
Publisher
Wiley
Published
2011-05-05
Volume
49
Issue
12
Pages
832-864
ISSN
  • 0887-6266 (ISSN-L)
  • 1099-0488
DOI
10.1002/polb.22259
PMC
PMC3136871
OpenAlex
W1980328470
Cited by
2,206
References
7
Citations by year
2026: 83 · 2025: 143 · 2024: 139 · 2023: 184 · 2022: 194 · 2021: 176 · 2020: 195 · 2019: 231 · 2018: 199 · 2017: 184 · 2016: 162 · 2015: 106 · 2014: 89 · 2013: 58 · 2012: 54
FWCI
26.11
Type
journal article
Language
en
Open access
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Journal of Polymer Science Part B Polymer Physics (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR052536)
Topics
  • Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
Keywords
biodegradable polymers, polymeric biomaterials, surgical sutures, implants, tissue engineering, drug delivery, natural polymers, synthetic polymers, polymer degradation, tissue mechanics

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