The DOI matches its Crossref record.
Characterization of intact microorganisms by MALDI mass spectrometry
Abstract
I. Introduction 157 II. MALDI‐TOF Spectra of Biomarkers 158 III. Instrumentation 158 IV. Sample Introduction 160 V. Preparation of Microorganism Samples for MALDI Analysis 161 VI. Characterization of MALDI Biomarkers 162 VII. Data Analysis: Fingerprint Libraries, Statistical Methods, Bioinformatics 163 VIII. Applications 165 IX. Summary and Envoi 166 Acknowledgments 166 References 166 The application of MALDI mass spectrometry to desorb protein biomarkers from intact viruses, bacteria, fungus, and spores is the focus of this review. Instrumentation, sample collection, sample preparation, and algorithms for data analysis are summarized. Optimally these analyses should be carried out in less than five minutes. Successful applications are discussed from biotechnology, cell biology, and the pharmaceutical industry. © 2002 John Wiley & Sons, Inc., Mass Spec Rev 20:157–171, 2001
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Water Analysis: Emerging Contaminants and Current Issues
Richardson, S. D., & Ternes, T. A. (2014) · Analytical Chemistry · doi:10.1021/ac500508t · Cited by 2,144
Mellmann, A., Cloud, J., Maier, T., Keckevoet, U., Ramminger, I., Iwen, P., Dunn, J., Hall, G., Wilson, D., LaSala, P., et al. (2008) · Journal of Clinical Microbiology · doi:10.1128/jcm.00157-08 · Cited by 435
Best practices and benchmarks for intact protein analysis for top-down mass spectrometry
Donnelly, D. P., Rawlins, C. M., DeHart, C. J., Fornelli, L., Schachner, L. F., Lin, Z., Lippens, J. L., Aluri, K. C., Sarin, R., Chen, B., et al. (2019) · Nature Methods · doi:10.1038/s41592-019-0457-0 · Cited by 377
Can MALDI-TOF Mass Spectrometry Reasonably Type Bacteria?
Sauget, M., Valot, B., Bertrand, X., & Hocquet, D. (2017) · Trends in Microbiology · doi:10.1016/j.tim.2016.12.006 · Cited by 214
Detection of Malaria Parasites in Blood by Laser Desorption Mass Spectrometry
Demirev, P. A., Feldman, A. B., Kongkasuriyachai, D., Scholl, P., Sullivan, & Kumar, N. (2002) · Analytical Chemistry · doi:10.1021/ac025621k · Cited by 82
Self-citation
Metadata
- Authors
- Fenselau, C., & Demirev, P. A.
- Venue
- Mass Spectrometry Reviews
- Publisher
- Wiley
- Published
- 2001-01
- Volume
- 20
- Issue
- 4
- Pages
- 157-171
- ISSN
- 0277-7037 (ISSN-L)
- 1098-2787
- OpenAlex
- W1974279612
- Cited by
- 834
- References
- 0
- FWCI
- 14.81
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Characterization of intact microorganisms by MALDI mass spectrometry. https://app.cochat.ai/papers/10.1002/mas.10004
- The paper
- Fenselau, C., & Demirev, P. A. (2001). Characterization of intact microorganisms by MALDI mass spectrometry. Mass Spectrometry Reviews. https://doi.org/10.1002/mas.10004
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
