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Matrix effects in quantitative pesticide analysis using liquid chromatography–mass spectrometry

Niessen, W.M.A., Manini, P., Andreoli, R.·2006·Mass Spectrometry Reviews

Abstract

Combined liquid chromatography–mass spectrometry using electrospray or atmospheric‐pressure chemical ionization has become an important tool in the quantitative analysis of pesticide residues in various matrices in relation to environmental analysis, food safety, and biological exposure monitoring. One of the major problems in the quantitative analysis using LC–MS is that compound and matrix‐dependent response suppression or enhancement may occur, the so‐called matrix effect. This article reviews issues related to matrix effects, focusing on quantitative pesticide analysis, but also paying attention to expertise with respect to matrix effects acquired in other application areas of LC–MS, especially quantitative bioanalysis in the course of drug development. © 2006 Wiley Periodicals, Inc.

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Metadata

Authors
Niessen, W. M. A., Manini, P., & Andreoli, R.
Venue
Mass Spectrometry Reviews
Publisher
Wiley
Published
2006-06-16
Volume
25
Issue
6
Pages
881-899
ISSN
  • 0277-7037 (ISSN-L)
  • 1098-2787
OpenAlex
W2078470673
Cited by
435
References
0
FWCI
32.44
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Matrix effects in quantitative pesticide analysis using liquid chromatography–mass spectrometry. https://app.cochat.ai/papers/10.1002/mas.20097
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Niessen, W. M. A., Manini, P., & Andreoli, R. (2006). Matrix effects in quantitative pesticide analysis using liquid chromatography–mass spectrometry. Mass Spectrometry Reviews. https://doi.org/10.1002/mas.20097

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