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Cited by 585

The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.

A meta‐analysis of six prospective studies of falling in Parkinson's disease

Pickering, Ruth M., Grimbergen, Yvette A.M., Rigney, Una, Ashburn, Ann, Mazibrada, Gordon, Wood, Brian, Gray, Peggy, Kerr, Graham, Bloem, Bastiaan R.·2007·Movement Disorders
DOI 10.1002/mds.21598
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Abstract

Recurrent falls are a disabling feature of Parkinson's disease (PD). We have estimated the incidence of falling over a prospective 3 month follow‐up from a large sample size, identified predictors for falling for PD patients repeated this analysis for patients without prior falls, and examined the risk of falling with increasing disease severity. We pooled six prospective studies of falling in PD (n = 473), and examined the predictive power of variables that were common to most studies. The 3‐month fall rate was 46% (95% confidence interval: 38–54%). Interestingly, even among subjects without prior falls, this fall rate was 21% (12–35%). The best predictor of falling was two or more falls in the previous year (sensitivity 68%; specificity 81%). The risk of falling rose as UPDRS increased, to about a 60% chance of falling for UPDRS values 25 to 35, but remained at this level thereafter with a tendency to taper off towards later disease stages. These results confirm the high frequency of falling in PD, as almost 50% of patients fell during a short period of only 3 months. The strongest predictor of falling was prior falls in the preceding year, but even subjects without any prior falls had a considerable risk of sustaining future falls. Disease severity was not a good predictor of falls, possibly due to the complex U‐shaped relation with falls. Early identification of the very first fall therefore remains difficult, and new prediction methods must be developed. © 2007 Movement Disorder Society

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Metadata

Authors
Pickering, R. M., Grimbergen, Y. A. M., Rigney, U., Ashburn, A., Mazibrada, G., Wood, B., Gray, P., Kerr, G., & Bloem, B. R.
Venue
Movement Disorders
Publisher
Wiley
Published
2007-10-15
Volume
22
Issue
13
Pages
1892-1900
ISSN
  • 0885-3185 (ISSN-L)
  • 1531-8257
DOI
10.1002/mds.21598
OpenAlex
W2114022278
Cited by
585
References
30
FWCI
45.81
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: A meta‐analysis of six prospective studies of falling in Parkinson's disease. https://app.cochat.ai/papers/10.1002/mds.21598
The paper
Pickering, R. M., Grimbergen, Y. A. M., Rigney, U., Ashburn, A., Mazibrada, G., Wood, B., Gray, P., Kerr, G., & Bloem, B. R. (2007). A meta‐analysis of six prospective studies of falling in Parkinson's disease. Movement Disorders. https://doi.org/10.1002/mds.21598

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.