Tai chi and postural stability in patients with Parkinson's disease
Open accessAbstract
BACKGROUND: Patients with Parkinson's disease have substantially impaired balance, leading to diminished functional ability and an increased risk of falling. Although exercise is routinely encouraged by health care providers, few programs have been proven effective. METHODS: We conducted a randomized, controlled trial to determine whether a tailored tai chi program could improve postural control in patients with idiopathic Parkinson's disease. We randomly assigned 195 patients with stage 1 to 4 disease on the Hoehn and Yahr staging scale (which ranges from 1 to 5, with higher stages indicating more severe disease) to one of three groups: tai chi, resistance training, or stretching. The patients participated in 60-minute exercise sessions twice weekly for 24 weeks. The primary outcomes were changes from baseline in the limits-of-stability test (maximum excursion and directional control; range, 0 to 100%). Secondary outcomes included measures of gait and strength, scores on functional-reach and timed up-and-go tests, motor scores on the Unified Parkinson's Disease Rating Scale, and number of falls. RESULTS: The tai chi group performed consistently better than the resistance-training and stretching groups in maximum excursion (between-group difference in the change from baseline, 5.55 percentage points; 95% confidence interval [CI], 1.12 to 9.97; and 11.98 percentage points; 95% CI, 7.21 to 16.74, respectively) and in directional control (10.45 percentage points; 95% CI, 3.89 to 17.00; and 11.38 percentage points; 95% CI, 5.50 to 17.27, respectively). The tai chi group also performed better than the stretching group in all secondary outcomes and outperformed the resistance-training group in stride length and functional reach. Tai chi lowered the incidence of falls as compared with stretching but not as compared with resistance training. The effects of tai chi training were maintained at 3 months after the intervention. No serious adverse events were observed. CONCLUSIONS: Tai chi training appears to reduce balance impairments in patients with mild-to-moderate Parkinson's disease, with additional benefits of improved functional capacity and reduced falls. (Funded by the National Institute of Neurological Disorders and Stroke; ClinicalTrials.gov number, NCT00611481.).
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Tai Chi following 24 weeks of twice weekly sessions leads to improved stride length and maximum excursion and reduced falls compared to resistance training or stretching in Parkinson's disease.
“Findings from these studies show that, following 24 weeks of twice weekly sessions, Tai Chi leads to improved stride length and maximum excursion as well as reduced falls compared to resistance training or stretching.”
From Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease (2013) · cites this paper as [17]
Tai Chi benefits were retained for at least 2 months.
“These benefits were retained for at least 2 months 17.”
From Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease (2013) · cites this paper as [17]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282 · see citing works
The Timed “Up & Go”: A Test of Basic Functional Mobility for Frail Elderly Persons
Podsiadlo, D., & Richardson, S. (1991) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1991.tb01616.x · Cited by 14,418 · see citing works
Parkinsonism: onset, progression, and mortality
Hoehn, M. M., & Yahr, M. D. (1967) · Neurology · doi:10.1212/wnl.17.5.427 · Cited by 12,107 · see citing works
The physical activity scale for the elderly (PASE): Development and evaluation
Washburn, R. A., Smith, K. W., Jette, A. M., & Janney, C. A. (1993) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(93)90053-4 · Cited by 3,183 · see citing works
Physical Activity and Public Health in Older Adults
Nelson, M. E., Rejeski, W. J., Blair, S. N., Duncan, P. W., Judge, J. O., King, A. C., Macera, C. A., & Castaneda‐Sceppa, C. (2007) · Circulation · doi:10.1161/circulationaha.107.185650 · Cited by 2,991 · see citing works
Functional Reach: A New Clinical Measure of Balance
Duncan, P. W., Weiner, D. K., Chandler, J., & Studenski, S. A. (1990) · Journal of Gerontology · doi:10.1093/geronj/45.6.m192 · Cited by 2,876 · see citing works
Diagnostic Criteria for Parkinson Disease
Gelb, D. J., Oliver, E., & Gilman, S. (1999) · Archives of Neurology · doi:10.1001/archneur.56.1.33 · Cited by 2,822 · see citing works
Members of the UPDRS Development Committee. Unified Parkinson's Disease Rating Scale
Fahn, S. (1987) · Medical Entomology and Zoology · Cited by 2,165 · see citing works
NELSON, M. E., REJESKI, W. J., BLAIR, S. N., DUNCAN, P. W., JUDGE, J. O., KING, A. C., MACERA, C. A., & CASTANEDA-SCEPPA, C. (2007) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3180616aa2 · Cited by 2,089 · see citing works
Wolf, S. L., Barnhart, H. X., Kutner, N. G., McNeely, E., Coogler, C., Xu, T., & Atlanta FICSIT Group (1996) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1996.tb01432.x · Cited by 1,142 · see citing works
Goodwin, V. A., Richards, S. H., Taylor, R. S., Taylor, A. H., & Campbell, J. L. (2008) · Movement Disorders · doi:10.1002/mds.21922 · Cited by 922 · see citing works
Tai Chi and Fall Reductions in Older Adults: A Randomized Controlled Trial
Li, F., Harmer, P., Fisher, K. J., McAuley, E., Chaumeton, N. R., Eckstrom, E., & Wilson, N. L. (2005) · The Journals of Gerontology Series A · doi:10.1093/gerona/60.2.187 · Cited by 750 · see citing works
Self-citationA meta‐analysis of six prospective studies of falling in Parkinson's disease
Pickering, R. M., Grimbergen, Y. A. M., Rigney, U., Ashburn, A., Mazibrada, G., Wood, B. H., Gray, P., Kerr, G., & Bloem, B. R. (2007) · Movement Disorders · doi:10.1002/mds.21598 · Cited by 587 · see citing works
Hirsch, M. A., Toole, T., Maitland, C., & Rider, R. A. (2003) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/s0003-9993(03)00046-7 · Cited by 456 · see citing works
Effects of a Group Exercise Program on Strength, Mobility, and Falls Among Fall-Prone Elderly Men
Rubenstein, L. Z., Josephson, K. R., Trueblood, P. R., Loy, S. F., Harker, J. O., Pietruszka, F. M., & Robbins, A. S. (2000) · The Journals of Gerontology Series A · doi:10.1093/gerona/55.6.m317 · Cited by 394 · see citing works
Li, F., Fisher, K. J., Harmer, P., Irbe, D., Tearse, R. G., & Weimer, C. (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52255.x · Cited by 370 · see citing works
Self-citationAshburn, A. (2001) · Age and Ageing · doi:10.1093/ageing/30.1.47 · Cited by 330 · see citing works
Tai Chi improves balance and mobility in people with Parkinson disease
Hackney, M. E., & Earhart, G. M. (2008) · Gait & Posture · doi:10.1016/j.gaitpost.2008.02.005 · Cited by 295 · see citing works
Voukelatos, A., Cumming, R. G., Lord, S. R., & Rissel, C. E. (2007) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2007.01244.x · Cited by 280 · see citing works
Principles and Practice of Movement Disorders
(2011) · Elsevier eBooks · doi:10.1016/c2009-0-44357-5 · Cited by 276 · see citing works
Dibble, L. E., Addison, O. R., & Papa, E. V. (2009) · Neurology Report · doi:10.1097/npt.0b013e3181990fcc · Cited by 242 · see citing works
Quality improvement in neurology: AAN epilepsy quality measures
Fountain, N. B., Ness, P. C. V., Swain‐Eng, R. J., Tonn, S. T., & Bever, C. T. (2010) · Neurology · doi:10.1212/wnl.0b013e318203e9d1 · Cited by 227 · see citing works
Resistance Training and Gait Function in Patients with Parkinson’s Disease
Scandalis, T. A., Bosak, A. M., Berliner, J. C., Helman, L. L., & Wells, M. R. (2001) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/00002060-200101000-00011 · Cited by 222 · see citing works
Functional reach: J.A new clinical measure of balance
Duncan, P. (1990) · The Journals of Gerontology Series A · Cited by 183 · see citing works
Teaching tape for the motor section of the unified Parkinson's disease rating scale
Goetz, C. G., Stebbins, G. T., Chmura, T. A., Fahn, S., Klawans, H. L., & MARSDEN, C. D. (1995) · Movement Disorders · doi:10.1002/mds.870100305 · Cited by 154 · see citing works
Weighted Vest Exercise Improves Indices of Fall Risk in Older Women
Shaw, J. M., & Snow, C. M. (1998) · The Journals of Gerontology Series A · doi:10.1093/gerona/53a.1.m53 · Cited by 141 · see citing works
Translation of an Effective Tai Chi Intervention Into a Community-Based Falls-Prevention Program
Li, F., Harmer, P., Glasgow, R. E., Mack, K. A., Sleet, D. A., Fisher, K. J., Kohn, M. A., Millet, L. M., Mead, J., Xu, J., et al. (2008) · American Journal of Public Health · doi:10.2105/ajph.2007.120402 · Cited by 129 · see citing works
Self-citationQuality improvement in neurology: AAN Parkinson disease quality measures
Cheng, E. M., Tonn, S. T., Swain‐Eng, R. J., Factor, S. A., Weiner, W. J., & Bever, C. T. (2010) · Neurology · doi:10.1212/wnl.0b013e3181ff96dd · Cited by 107 · see citing works
Physiotherapy for Parkinson's disease: a comparison of techniques
Deane, K. H., Jones, D. E., Ellis‐Hill, C., Clarke, C. E., Playford, E. D., & Ben‐Shlomo, Y. (2001) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002815 · Cited by 102 · see citing works
Tai Chi–Based Exercise for Older Adults with Parkinson’s Disease: A Pilot-Program Evaluation
Li, F., Harmer, P., Fisher, K. J., Xu, J., Fitzgerald, K., & Vongjaturapat, N. (2007) · Journal of Aging and Physical Activity · doi:10.1123/japa.15.2.139 · Cited by 72 · see citing works
Self-citationGreendale, G. A., Salem, G. J., Young, J. T., Damesyn, M. A., Marion, M., Wang, M., & Reuben, D. B. (2000) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2000.tb02651.x · Cited by 65 · see citing works
Dibble, L. E., Hale, T. F., Marcus, R. L., Gerber, J. P., & LaStayo, P. C. (2006) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2006.05.016 · Cited by 55 · see citing works
Psychogenic Movement Disorders
Fahn, S., Jankovic, J. J., Hallett, M., & Jenner, P. G. (2007) · Elsevier eBooks · doi:10.1016/b978-0-443-07941-2.50029-2 · Cited by 45 · see citing works
Developing the Medication Change Questionnaire
Paterson, C., Symons, L., Britten, N., & Bargh, J. (2004) · Journal of Clinical Pharmacy and Therapeutics · doi:10.1111/j.1365-2710.2004.00570.x · Cited by 13 · see citing works
The Role of Levodopa and Catechol-O-Methyltransferase Inhibitors
Nirenberg, M. J. (2005) · Elsevier eBooks · doi:10.1016/b978-0-7506-5428-9.50005-6 · Cited by 13 · see citing works
Physical therapy in Parkinson's disease
MacKay-Lyons, M. J., Turnbull, G., Comella, C. L., Stebbins, G. T., Brown-Toms, N., & Goetz, C. G. (1995) · Neurology · doi:10.1212/wnl.45.1.205 · Cited by 11 · see citing works
The Medical Management of Parkinson's Disease
Schapira, A. H. V. (2005) · Elsevier eBooks · doi:10.1016/b978-0-7506-5428-9.50010-x · Cited by 8 · see citing works
Physical therapy in Parkinson's disease
Graciès, J., Tse, W., Lugassy, M. M., & FRANK, J. (2007) · Handbook of clinical neurology · doi:10.1016/s0072-9752(07)84030-9 · Cited by 5 · see citing works
Flagged first, then by citations
1 of the 39 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Fox, S. H., Katzenschlager, R., Lim, S., Barton, B. R., de Bie, R. M. A., Seppi, K., Coelho, M. M., & Sampaio, C. (2018) · Movement Disorders · doi:10.1002/mds.27372 · Cited by 1,009 · see citing works
Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease
Petzinger, G. M., Fisher, B. E., McEwen, S., Beeler, J. A., Walsh, J. P., & Jakowec, M. W. (2013) · The Lancet Neurology · doi:10.1016/s1474-4422(13)70123-6 · Cited by 798 · see citing works
Su, D., Cui, Y., He, C., Yin, P., Bai, R., Zhu, J., Lam, J. S. T., Zhang, J., Yan, R., Zheng, X., et al. (2025) · BMJ · doi:10.1136/bmj-2024-080952 · Cited by 698 · see citing works
Long-term effects of exercise and physical therapy in people with Parkinson disease
Mak, K. Y., Wong-Yu, I. S. K., Shen, X., & Chung, C. L. H. (2017) · Nature Reviews Neurology · doi:10.1038/nrneurol.2017.128 · Cited by 552 · see citing works
Schenkman, M., Moore, C. G., Kohrt, W. M., Hall, D. A., Delitto, A., Comella, C. L., Josbeno, D. A., Christiansen, C. L., Berman, B. D., Kluger, B. M., et al. (2018) · JAMA Neurology · doi:10.1001/jamaneurol.2017.3517 · Cited by 515 · see citing works
Rehabilitation for Parkinson's disease: Current outlook and future challenges
Abbruzzese, G., Marchese, R., Avanzino, L., & Pelosin, E. (2015) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2015.09.005 · Cited by 437 · see citing works
Neuromechanical Principles Underlying Movement Modularity and Their Implications for Rehabilitation
Ting, L. H., Chiel, H. J., Trumbower, R. D., Allen, J. L., McKay, J. L., Hackney, M. E., & Kesar, T. M. (2015) · Neuron · doi:10.1016/j.neuron.2015.02.042 · Cited by 410 · see citing works
Randomized Clinical Trial of 3 Types of Physical Exercise for Patients With Parkinson Disease
Shulman, L. M., Katzel, L. I., Ivey, F. M., Sorkin, J. D., Favors, K., Anderson, K. E., Smith, B. A., Reich, S. G., Weiner, W. J., & Macko, R. F. (2013) · JAMA Neurology · doi:10.1001/jamaneurol.2013.646 · Cited by 410 · see citing works
Fibromyalgia Syndrome: Etiology, Pathogenesis, Diagnosis, and Treatment
Bellato, E., Marini, E., Castoldi, F., Barbasetti, N., Mattei, L., Bonasia, D. E., & Blonna, D. (2012) · Pain Research and Treatment · doi:10.1155/2012/426130 · Cited by 389 · see citing works
Quantitative wearable sensors for objective assessment of Parkinson's disease
Maetzler, W., Domingos, J., Srulijes, K., Ferreira, J. J., & Bloem, B. R. (2013) · Movement Disorders · doi:10.1002/mds.25628 · Cited by 374 · see citing works
Magrinelli, F., Picelli, A., Tocco, P., Federico, A., Roncari, L., Smania, N., Zanette, G., & Tamburin, S. (2016) · Parkinson s Disease · doi:10.1155/2016/9832839 · Cited by 373 · see citing works
Paillard, T., Rolland, Y., & Barreto, P. D. S. (2015) · Journal of Clinical Neurology · doi:10.3988/jcn.2015.11.3.212 · Cited by 366 · see citing works
Falls in Parkinson's disease: A complex and evolving picture
Fasano, A. A., Canning, C. G., Hausdorff, J. M., Lord, S., & Rochester, L. (2017) · Movement Disorders · doi:10.1002/mds.27195 · Cited by 365 · see citing works
Barriers to Exercise in People With Parkinson Disease
Ellis, T. D., Boudreau, J. K., DeAngelis, T. R., Brown, L. E., Cavanaugh, J. T., Earhart, G. M., Ford, M. P., Foreman, K. B., & Dibble, L. E. (2013) · Physical Therapy · doi:10.2522/ptj.20120279 · Cited by 342 · see citing works
A two‐year randomized controlled trial of progressive resistance exercise for Parkinson's disease
Corcos, D. M., Robichaud, J. A., David, F. J., Leurgans, S. E., Vaillancourt, D. E., Poon, C., Rafferty, M. R., Kohrt, W. M., & Comella, C. L. (2013) · Movement Disorders · doi:10.1002/mds.25380 · Cited by 328 · see citing works
Henderson, E. J., Lord, S. R., Brodie, M. A. D., Gaunt, D., Lawrence, A. D., Close, J., Whone, A. L., & Ben‐Shlomo, Y. (2016) · The Lancet Neurology · doi:10.1016/s1474-4422(15)00389-0 · Cited by 304 · see citing works
Effects of Exercise on Falls, Balance, and Gait Ability in Parkinson’s Disease
Shen, X., Wong-Yu, I. S. K., & Mak, K. Y. (2015) · Neurorehabilitation and neural repair · doi:10.1177/1545968315613447 · Cited by 278 · see citing works
Nonpharmacological treatments for patients with Parkinson's disease
Bloem, B. R., de Vries, N. M., & Ebersbach, G. (2015) · Movement Disorders · doi:10.1002/mds.26363 · Cited by 273 · see citing works
Romenets, S. R., Anang, J. B. M., Fereshtehnejad, S., Pelletier, A., & Postuma, R. B. (2015) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2015.01.015 · Cited by 266 · see citing works
Exercise for falls prevention in Parkinson disease
Canning, C. G., Sherrington, C., Lord, S. R., Close, J., Heritier, S. R., Heller, G. Z., Howard, K., Allen, N. E., Latt, M. D., Murray, S. M., et al. (2014) · Neurology · doi:10.1212/wnl.0000000000001155 · Cited by 263 · see citing works
Volpe, D., Signorini, M., Marchetto, A., Lynch, T., & Morris, M. E. (2013) · BMC Geriatrics · doi:10.1186/1471-2318-13-54 · Cited by 260 · see citing works
Raefsky, S. M., & Mattson, M. P. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.11.045 · Cited by 274 · see citing works
Song, R., Grabowska, W. A., Park, M., Osypiuk, K., Vergara-Diaz, G. P., Bonato, P., Hausdorff, J. M., Fox, M., Sudarsky, L. R., Macklin, E. A., et al. (2017) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2017.05.019 · Cited by 240 · see citing works
Postural Instability in Patients with Parkinson’s Disease
Kim, S. D., Allen, N. E., Canning, C. G., & Fung, V. S. C. (2012) · CNS Drugs · doi:10.1007/s40263-012-0012-3 · Cited by 238 · see citing works
Effects of exercise on mobility in people with Parkinson's disease
van der Kolk, N. M., & King, L. A. (2013) · Movement Disorders · doi:10.1002/mds.25658 · Cited by 235 · see citing works
Osborne, J. A., Botkin, R., Colón-Semenza, C., DeAngelis, T. R., Gallardo, O. G., Kosakowski, H., Martello, J. P., Pradhan, S. D., Rafferty, M. R., Readinger, J. L., et al. (2021) · Physical Therapy · doi:10.1093/ptj/pzab302 · Cited by 232 · see citing works
Effect of Tai Chi on Physical Function, Fall Rates and Quality of Life Among Older Stroke Survivors
Taylor‐Piliae, R. E., Hoke, T. M., Hepworth, J. T., Latt, L. D., Najafi, B., & Coull, B. M. (2014) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2014.01.001 · Cited by 224 · see citing works
Physiotherapy for Parkinson's disease: a comparison of techniques.
Tomlinson, C., Herd, C. P., Clarke, C., Meek, C., Patel, S., Stowe, R., Deane, K. H. O., Shah, L., Sackley, C., Wheatley, K., et al. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002815.pub2 · Cited by 243 · see citing works
Physical activity and the brain: A review of this dynamic, bi-directional relationship
Loprinzi, P. D., Herod, S. M., Cardinal, B. J., & Noakes, T. D. (2013) · Brain Research · doi:10.1016/j.brainres.2013.10.004 · Cited by 222 · see citing works
The benefits and mechanisms of exercise training for Parkinson's disease
Feng, Y.-S., Yang, S., Tan, Z., Wang, M., Xing, Y., Dong, F., & Zhang, F. (2020) · Life Sciences · doi:10.1016/j.lfs.2020.117345 · Cited by 222 · see citing works
The Effects of Adapted Tango on Spatial Cognition and Disease Severity in Parkinson's Disease
McKee, K. E., & Hackney, M. E. (2013) · Journal of Motor Behavior · doi:10.1080/00222895.2013.834288 · Cited by 218 · see citing works
Physical exercise for people with Parkinson’s disease: a systematic review and network meta-analysis
Ernst, M., Folkerts, A., Gollan, R., Lieker, E., Caro-Valenzuela, J., Adams, A., Cryns, N., Monsef, I., Dresen, A., Roheger, M., et al. (2023) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013856.pub2 · Cited by 231 · see citing works
The quest for modernisation of traditional Chinese medicine
Xu, Q., Bauer, R., Hendry, B. M., Fan, T.-P., Zhao, Z., Duez, P., Simmonds, M. S. J., Witt, C. M., Lü, A., Robinson, N., et al. (2013) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-13-132 · Cited by 216 · see citing works
Benefits of Exercise in the Older Population
Galloza‐Otero, J. C., Castillo, B., & Micheo, W. F. (2017) · Physical Medicine and Rehabilitation Clinics of North America · doi:10.1016/j.pmr.2017.06.001 · Cited by 215 · see citing works
Therapies in Parkinsonʼs disease
Jankovic, J. J., & Poewe, W. H. (2012) · Current Opinion in Neurology · doi:10.1097/wco.0b013e3283542fc2 · Cited by 213 · see citing works
Liao, Y.-Y., Yang, Y., Cheng, S., Wu, Y., Fuh, J., & Wang, R. (2014) · Neurorehabilitation and neural repair · doi:10.1177/1545968314562111 · Cited by 208 · see citing works
The Effects of Physical Activity in Parkinson’s Disease: A Review
Lauzé, M., Daneault, J., & Duval, C. (2016) · Journal of Parkinson s Disease · doi:10.3233/jpd-160790 · Cited by 204 · see citing works
Canning, C. G., Paul, S. S., & Nieuwboer, A. (2014) · Neurodegenerative Disease Management · doi:10.2217/nmt.14.22 · Cited by 201 · see citing works
Tai Chi Chuan in Medicine and Health Promotion
Lan, C., Chen, S., Lai, J., & Wong, M. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/502131 · Cited by 193 · see citing works
Nanoformulations of Herbal Extracts in Treatment of Neurodegenerative Disorders
Moradi, S. Z., Momtaz, S., Bayrami, Z., Farzaei, M. H., & Abdollahi, M. R. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.00238 · Cited by 181 · see citing works
van der Marck, M. A., Klok, M., Okun, M. S., Giladi, N., Munneke, M., & Bloem, B. R. (2014) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2013.10.030 · Cited by 177 · see citing works
Li, F., Harmer, P., Fitzgerald, K. M., Eckstrom, E., Akers, L. G., Chou, L., Pidgeon, D., Voit, J., & Winters‐Stone, K. M. (2018) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2018.3915 · Cited by 177 · see citing works
Self-citationDefining the Clinically Meaningful Difference in Gait Speed in Persons With Parkinson Disease
Hass, C. J., Bishop, M. D., Moscovich, M., Stegemöller, E. L., Skinner, J. W., Malaty, I. A., Shukla, A. W., McFarland, N. R., & Okun, M. S. (2014) · Neurology Report · doi:10.1097/npt.0000000000000055 · Cited by 174 · see citing works
Clinical Evidence of Exercise Benefits for Stroke
Han, P., Zhang, W., Li, K., Ma, Y., Fu, L., Jia, L., Yu, H., Chen, X., Hou, L., Wang, L., et al. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-981-10-4304-8_9 · Cited by 178 · see citing works
Systematic review and meta-analysis: Tai Chi for preventing falls in older adults
Huang, Z.-G., Feng, Y.-H., Li, Y.-H., & Lv, C.-S. (2017) · BMJ Open · doi:10.1136/bmjopen-2016-013661 · Cited by 172 · see citing works
Gao, Q., Leung, K. L., Yang, Y., Wei, Q., Guan, M., Jia, C., & He, C. (2014) · Clinical Rehabilitation · doi:10.1177/0269215514521044 · Cited by 172 · see citing works
Niu, S., Zhang, L., Zhang, L., Zhuang, S., Zhan, X., Chen, W., Du, S., Yin, L., You, R., Li, C., et al. (2016) · Theranostics · doi:10.7150/thno.16562 · Cited by 173 · see citing works
Dopamine overdose hypothesis: Evidence and clinical implications
Vaillancourt, D. E., Schonfeld, D., Kwak, Y., Bohnen, N. I., & Seidler, R. D. (2013) · Movement Disorders · doi:10.1002/mds.25687 · Cited by 171 · see citing works
Tai Chi and Qigong for the Treatment and Prevention of Mental Disorders
Abbott, R. B., & Lavretsky, H. (2013) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2013.01.011 · Cited by 170 · see citing works
Evidence for Early and Regular Physical Therapy and Exercise in Parkinson’s Disease
Ellis, T., Colón-Semenza, C., Deangelis, T., Thomas, C. A., Hilaire, M. S., Earhart, G., & Dibble, L. (2021) · Seminars in neurology · doi:10.1055/s-0041-1725133 · Cited by 135 · see citing works
Olson, M. C., Lockhart, T. E., & LIEBERMAN, A. N. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.00062 · Cited by 155 · see citing works
A Randomized Controlled Trial to Reduce Falls in People With Parkinson’s Disease
Morris, M. E., Menz, H. B., McGinley, J. L., Watts, J. J., Huxham, F. E., Murphy, A., Danoudis, M. E., & Iansek, R. (2015) · Neurorehabilitation and neural repair · doi:10.1177/1545968314565511 · Cited by 152 · see citing works
Health benefits of tai chi: What is the evidence?
Huston, P., & McFarlane, B. (2016) · PubMed Central · Cited by 148 · see citing works
Shih, M.-C., Wang, R., Cheng, S.-J., & Yang, Y. (2016) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/s12984-016-0185-y · Cited by 147 · see citing works
Tao, J., Liu, J., Egorova, N., Chen, X., Sun, S., Xue, X., Huang, J., Zheng, G., Wang, Q., Chen, L., et al. (2016) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2016.00025 · Cited by 145 · see citing works
Shu, H., Yang, T., Yu, S., Huang, H., Jiang, L.-L., Gu, J., & Kuang, Y.-Q. (2014) · PLoS ONE · doi:10.1371/journal.pone.0100503 · Cited by 144 · see citing works
Burschka, J. M., Keune, P. M., Oy, U. H., Oschmann, P., & Kuhn, P. (2014) · BMC Neurology · doi:10.1186/s12883-014-0165-4 · Cited by 140 · see citing works
Oguh, O., Eisenstein, A., Kwasny, M., & Simuni, T. (2014) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2014.09.008 · Cited by 138 · see citing works
Sardinian Folk Dance for Individuals with Parkinson's Disease: A Randomized Controlled Pilot Trial
Solla, P., Cugusi, L., Bertoli, M., Cereatti, A., Croce, U. D., Pani, D., Fadda, L., Cannas, A., Marrosu, F., Defazio, G., et al. (2019) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2018.0413 · Cited by 137 · see citing works
Wayne, P. M., Berkowitz, D., Litrownik, D., Buring, J. E., & Yeh, G. Y. (2014) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2014.05.005 · Cited by 136 · see citing works
Jones, K. D., Sherman, C. A., Mist, S. D., Carson, J. W., Bennett, R. M., & Li, F. (2012) · Clinical Rheumatology · doi:10.1007/s10067-012-1996-2 · Cited by 133 · see citing works
Self-citationReynolds, G., Otto, M. W., Ellis, T. D., & Cronin‐Golomb, A. (2015) · Movement Disorders · doi:10.1002/mds.26484 · Cited by 132 · see citing works
The best medicine? The influence of physical activity and inactivity on Parkinson's disease
LaHue, S. C., Comella, C. L., & Tanner, C. M. (2016) · Movement Disorders · doi:10.1002/mds.26728 · Cited by 133 · see citing works
Yang, Y. X., Li, X.-Y., Gong, L., Zhu, Y., & Hao, Y. (2014) · PLoS ONE · doi:10.1371/journal.pone.0102942 · Cited by 129 · see citing works
Chung, C. L. H., Thilarajah, S., & Tan, D. M. L. (2015) · Clinical Rehabilitation · doi:10.1177/0269215515570381 · Cited by 127 · see citing works
Paul, S. S., Sherrington, C., Canning, C. G., Fung, V. S. C., Close, J., & Lord, S. R. (2013) · Neurorehabilitation and neural repair · doi:10.1177/1545968313508470 · Cited by 126 · see citing works
Amano, J., Nocera, J. R., Vallabhajosula, S., Juncos, J. L., Gregor, R. J., Waddell, D. E., Wolf, S. L., & Hass, C. J. (2013) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2013.06.007 · Cited by 125 · see citing works
Deuel, L. M., & Seeberger, L. (2020) · Neurotherapeutics · doi:10.1007/s13311-020-00900-y · Cited by 131 · see citing works
Gait Disorders in Parkinson's Disease: Assessment and Management
Chen, P., Wang, R., Liou, D.-J., & Shaw, J. (2013) · International journal of gerontology · doi:10.1016/j.ijge.2013.03.005 · Cited by 123 · see citing works
Duncan, R. P., Leddy, A. L., Cavanaugh, J. T., Dibble, L. E., Ellis, T. D., Ford, M. P., Foreman, K. B., & Earhart, G. M. (2012) · Physical Therapy · doi:10.2522/ptj.20120302 · Cited by 122 · see citing works
Aquatic Exercise Therapy for People With Parkinson Disease: A Randomized Controlled Trial
Carroll, L. M., Volpe, D., Morris, M. E., Saunders, J. A., & Clifford, A. M. (2017) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2016.12.006 · Cited by 122 · see citing works
Zhang, L., Wang, S., Chen, H., & A-zhen, Y. (2015) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2015.11.020 · Cited by 117 · see citing works
Managing Gait, Balance, and Posture in Parkinson’s Disease
Debu, B. H. G., Godeiro-Junior, C. D. O., Lino, J. C., & Moro, E. (2018) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-018-0828-4 · Cited by 116 · see citing works
Technology-Assisted Balance and Gait Training Reduces Falls in Patients With Parkinson’s Disease
Shen, X., & Mak, K. Y. (2014) · Neurorehabilitation and neural repair · doi:10.1177/1545968314537559 · Cited by 115 · see citing works
Motivators and Barriers to Exercise in Parkinson’s Disease
Afshari, M., Yang, A., & Bega, D. (2017) · Journal of Parkinson s Disease · doi:10.3233/jpd-171173 · Cited by 115 · see citing works
Li, G., Huang, P., Cui, S., Tan, Y.-Y., Shen, X., Shen, X., Jiang, Q.-Y., Huang, P., He, G.-Y., Li, B., et al. (2022) · Translational Neurodegeneration · doi:10.1186/s40035-022-00280-7 · Cited by 115 · see citing works
Ni, X., Liu, S., Lu, F., Shi, X., & Guo, X. (2014) · PLoS ONE · doi:10.1371/journal.pone.0099377 · Cited by 116 · see citing works
Exercise for Parkinson's disease
Mak, K. Y., & Wong-Yu, I. S. K. (2019) · International review of neurobiology · doi:10.1016/bs.irn.2019.06.001 · Cited by 116 · see citing works
Current Pharmaceutical Treatments and Alternative Therapies of Parkinson's Disease
Dong, J., Cui, Y., Li, S., & Le, W. (2016) · Current Neuropharmacology · doi:10.2174/1570159x14666151120123025 · Cited by 112 · see citing works
Clinical syndromes: Parkinsonian gait
Ebersbach, G., Moreau, C., Gandor, F., Defebvre, L., & Devos, D. (2013) · Movement Disorders · doi:10.1002/mds.25675 · Cited by 107 · see citing works
Shen, X., & Mak, K. Y. (2014) · Neurorehabilitation and neural repair · doi:10.1177/1545968313517752 · Cited by 108 · see citing works
Exercise-Induced Neuroprotection of the Nigrostriatal Dopamine System in Parkinson's Disease
Hou, L., Chen, W., Liu, X., Qiao, D., & Zhou, F.-M. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00358 · Cited by 105 · see citing works
Homann, B., Plaschg, A., Grundner, M., Haubenhofer, A., Griedl, T. A., Ivanic, G. M., Hofer, E., Fazekas, F., & Homann, C. N. (2013) · BMJ Open · doi:10.1136/bmjopen-2013-003367 · Cited by 104 · see citing works
European Review of Aging and Physical Activity
(2013) · European Review of Aging and Physical Activity · doi:10.1007/11556.1861-6909 · Cited by 103 · see citing works
Effects of physical activity in Parkinson's disease: A new tool for rehabilitation
Borrione, P. (2014) · World Journal of Methodology · doi:10.5662/wjm.v4.i3.133 · Cited by 102 · see citing works
Tai Chi and Pulmonary Rehabilitation Compared for Treatment-Naive Patients With COPD
Polkey, M. I., Qiu, Z., Zhou, L., Zhu, M.-D., Wu, Y.-X., Chen, Y., Ye, S.-P., He, Y.-S., Jiang, M., He, B., et al. (2018) · CHEST Journal · doi:10.1016/j.chest.2018.01.053 · Cited by 102 · see citing works
Effects of 24 wk of Treadmill Training on Gait Performance in Parkinson’s Disease
Nadeau, A., Pourcher, E., & Corbeil, P. (2013) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000144 · Cited by 102 · see citing works
Jin, X., Wang, L., Liu, S., Zhu, L., Loprinzi, P. D., & Fan, X. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17010031 · Cited by 105 · see citing works
Exercise Guidelines for Gait Function in Parkinson’s Disease: A Systematic Review and Meta-analysis
Ni, M., Hazzard, J. B., Signorile, J. F., & Luca, C. C. (2018) · Neurorehabilitation and neural repair · doi:10.1177/1545968318801558 · Cited by 100 · see citing works
Spruit, M. A. (2014) · European Respiratory Review · doi:10.1183/09059180.00008013 · Cited by 99 · see citing works
Highly Challenging Balance Program Reduces Fall Rate in Parkinson Disease
Sparrow, D., DeAngelis, T. R., Hendron, K. L., Thomas, C. A., Saint‐Hilaire, M., & Ellis, T. D. (2015) · Neurology Report · doi:10.1097/npt.0000000000000111 · Cited by 99 · see citing works
Lamotte, G., Rafferty, M. R., Prodoehl, J., Kohrt, W. M., Comella, C. L., Simuni, T., & Corcos, D. M. (2015) · Journal of Parkinson s Disease · doi:10.3233/jpd-140425 · Cited by 98 · see citing works
Morris, M. E., Taylor, N. F., Watts, J. J., Evans, A. H., Horne, M. K., Kempster, P. A., Danoudis, M. E., McGinley, J. L., Martin, C. L., & Menz, H. B. (2017) · Journal of physiotherapy · doi:10.1016/j.jphys.2017.02.015 · Cited by 98 · see citing works
Effects of individualized Tai-Chi on balance and lower-limb strength in older adults
Penn, I., Sung, W.-H., Lin, C.-H., Chuang, E. Y.-Y., Chuang, T., & Lin, P.-H. (2019) · BMC Geriatrics · doi:10.1186/s12877-019-1250-8 · Cited by 96 · see citing works
The Treatment Strategies for Neurodegenerative Diseases by Integrative Medicine
Chen, X., & Pan, W. (2015) · Integrative Medicine International · doi:10.1159/000381546 · Cited by 96 · see citing works
The Beneficial Role of Intensive Exercise on Parkinson Disease Progression
Frazzitta, G., Balbi, P., Maestri, R., Bertotti, G., Boveri, N., & Pezzoli, G. (2013) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/phm.0b013e31828cd254 · Cited by 98 · see citing works
Tsou, Y.-H., Shih, C.-T., Ching, C., Huang, J.-Y., Jen, C. J., Yu, L., Kuo, Y., Wu, F., & Chuang, J. (2014) · Experimental Neurology · doi:10.1016/j.expneurol.2014.09.021 · Cited by 95 · see citing works
Seymour, K. C., Pickering, R. M., Rochester, L., Roberts, H. C., Ballinger, C., Hulbert, S., Kunkel, D., Marian, I. R., Fitton, C., McIntosh, E., et al. (2019) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2018-319448 · Cited by 95 · see citing works
Li, F., Harmer, P., Liu, Y., Eckstrom, E., Fitzgerald, K. M., Stock, R. D., & Chou, L. (2013) · Movement Disorders · doi:10.1002/mds.25787 · Cited by 95 · see citing works
Self-citationTwo-Year Exercise Program Improves Physical Function in Parkinson’s Disease
Prodoehl, J., Rafferty, M. R., David, F. J., Poon, C., Vaillancourt, D. E., Comella, C. L., Leurgans, S. E., Kohrt, W. M., Corcos, D. M., & Robichaud, J. A. (2014) · Neurorehabilitation and neural repair · doi:10.1177/1545968314539732 · Cited by 94 · see citing works
- Authors
- Li, F., Harmer, P., Fitzgerald, K., Eckstrom, E., Stock, R., Galver, J., Maddalozzo, G., & Batya, S. S.
- Affiliations
- Oregon Research Institute (US)
- Willamette University (US)
- Oregon Health & Science University (US)
- Oregon State University (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2012-02-09
- Volume
- 366
- Issue
- 6
- Pages
- 511-519
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- PMC
- PMC3285459
- OpenAlex
- W2150072209
- Cited by
- 890
- References
- 39
- Citations by year
- 2026: 42 · 2025: 54 · 2024: 47 · 2023: 53 · 2022: 63 · 2021: 69 · 2020: 52 · 2019: 67 · 2018: 50 · 2017: 58 · 2016: 62 · 2015: 75 · 2014: 79 · 2013: 81 · 2012: 37
- FWCI
- 216.62
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke (NS047130, R01NS047130)
- Topics
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Balance, Gait, and Falls Prevention
- Health Sciences › Medicine › Rehabilitation › Stroke Rehabilitation and Recovery
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Diversity and Impact of Dance
- Keywords
- Tai Chi, Parkinson's disease, postural stability, balance disorders, falls, exercise intervention, resistance training, stretching, limits of stability test, gait, functional reach test, fall prevention
- MeSH terms
- Aged, Postural Balance, Female, Gait, Humans, Male, Parkinson Disease, Outcome Assessment, Health Care, Tai Ji, Muscle Stretching Exercises, Resistance Training
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review