Cited by 305Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement DisordersAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

The DOI matches its Crossref record; 40 of the 41 references it cites were found in a registry or an index.

Prevalence of anxiety disorders and anxiety subtypes in patients with Parkinson's disease

Open access

Pontone, Gregory M., Williams, James R., Anderson, Karen E., Chase, Gary, Goldstein, Susanne A., Grill, Stephen, Hirsch, Elaina S., Lehmann, Susan, Little, John T., Margolis, Russell L., Rabins, Peter V., Weiss, Howard D., Marsh, Laura·2009·Movement Disorders

DOI 10.1002/mds.22611PMC PMC2830642

Open this paper in CoChat — free account

Abstract

Anxiety disorders are common in Parkinson's disease (PD), but are not well characterized. This study determined the prevalence and clinical correlates of all DSM‐IV‐TR anxiety disorder diagnoses in a sample of 127 subjects with idiopathic PD who underwent comprehensive assessments administered by a psychiatrist and neurologist. A panel of six psychiatrists with expertise in geriatric psychiatry and/or movement disorders established by consensus all psychiatric diagnoses. Current and lifetime prevalence of at least one anxiety disorder diagnosis was 43% (n = 55) and 49% (n = 63), respectively. Anxiety disorder not otherwise specified, a DSM diagnosis used for anxiety disturbances not meeting criteria for defined subtypes, was the most common diagnosis (30% lifetime prevalence, n = 38). Compared with nonanxious subjects, panic disorder (n = 13) was associated with earlier age of PD onset [50.3 (12.2) vs. 61.0 (13.7) years, P < 0.01], higher rates of motor fluctuations [77% (10/13) vs. 39% (25/64), P = 0.01] and morning dystonia [38% (5/13) vs. 13% (8/62), P < 0.03]. This high prevalence of anxiety disorders, including disturbances often not meeting conventional diagnostic criteria, suggests that anxiety in PD is likely underdiagnosed and undertreated and refined characterization of anxiety disorders in PD is needed. In addition, certain anxiety subtypes may be clinically useful markers associated with disease impact in PD. © 2009 Movement Disorder Society

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1002/mds.22611

Cites

40 of 40 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.593 · Cited by 20,391
Parkinsonism: onset, progression, and mortality
Hoehn, M. M., & Yahr, M. D. (1967) · Neurology · doi:10.1212/wnl.17.5.427 · Cited by 12,107
Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR)
American Psychiatric Association (2000) · doi:10.1176/appi.books.9780890423349 · Cited by 11,069
Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases.
Hughes, A. J., Daniel, S. E., Kilford, L., & Lees, A. J. (1992) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.55.3.181 · Cited by 10,378
Stages in the development of Parkinson’s disease-related pathology
Braak, H., Ghebremedhin, E., Rüb, U., Bratzke, H., & Del Tredici, K. (2004) · Cell and Tissue Research · doi:10.1007/s00441-004-0956-9 · Cited by 2,689
Recent developments in Parkinson's disease
Fahn, S., Elton, R., MARSDEN, C. D., Calne, D. B., & Goldstein, M. (1986) · Raven Press eBooks · Cited by 2,306
Parkinsonism: Onset, progression, and mortality
Hoehn, M., & Yahr, M. (2011) · Neurology · doi:10.1212/01.wnl.0000405146.06300.91 · Cited by 1,888
A Review and Meta-Analysis of the Genetic Epidemiology of Anxiety Disorders
Hettema, J. M., Neale, M. C., & Kendler, K. S. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.10.1568 · Cited by 1,563
Best Estimate of Lifetime Psychiatric Diagnosis
Leckman, J. F. (1982) · Archives of General Psychiatry · doi:10.1001/archpsyc.1982.04290080001001 · Cited by 1,418
Parkinsonism
Hoehn, M. M. M., & Yahr, M. D. (1998) · Neurology · doi:10.1212/wnl.50.2.318 · Cited by 873

Show all 41 references

Research works printed but not linked: 2

First MB, 2002, Structured clinical interview for DSM‐IV‐TR axis I disorders, research version, patient edition. (SCID‐I/P). Biometrics Research 2002
10.1176/appi.neuropsych.18.1.130 · DOI

Sorted by citations

Anxiety disorders in older adults: a comprehensive review
Wolitzky-Taylor, K. B., Castriotta, N., Lenze, E. J., Stanley, M. A., & Craske, M. G. (2010) · Depression and Anxiety · doi:10.1002/da.20653 · Cited by 726
Circuit Mechanisms of Parkinson’s Disease
McGregor, M. M., & Nelson, A. (2019) · Neuron · doi:10.1016/j.neuron.2019.03.004 · Cited by 632
Prevalence of anxiety in Parkinson's disease: A systematic review and meta‐analysis
Broen, M. P. G., Narayen, N. E., Kuijf, M. L., Dissanayaka, N. N. W., & Leentjens, A. F. G. (2016) · Movement Disorders · doi:10.1002/mds.26643 · Cited by 457
Parkinson's disease: The quintessential neuropsychiatric disorder
Weintraub, D. A., & Burn, D. J. (2011) · Movement Disorders · doi:10.1002/mds.23664 · Cited by 422
The Parkinson Anxiety Scale (PAS): Development and validation of a new anxiety scale
Leentjens, A. F. G., Dujardin, K., Pontone, G. M., Starkstein, S. E., Weintraub, D., & Martinez‐Martin, P. (2014) · Movement Disorders · doi:10.1002/mds.25919 · Cited by 270
Self-citation
Homeostasis and metabolism of iron and other metal ions in neurodegenerative diseases
Chen, L., Shen, Q., Liu, Y., Zhang, Y., Sun, L., Ma, X., Song, N., & Xie, J. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-02071-0 · Cited by 279
Anxiety rating scales in Parkinson's disease: A validation study of the Hamilton anxiety rating scale, the Beck anxiety inventory, and the hospital anxiety and depression scale
Leentjens, A. F. G., Dujardin, K., Marsh, L., Richard, I. H., STARKSTEIN, S. E., & Martínez‐Martín, P. (2011) · Movement Disorders · doi:10.1002/mds.23184 · Cited by 233
Self-citation
Psychosis, apathy, depression and anxiety in Parkinson's disease
Gallagher, D. A., & Schrag, A. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.12.041 · Cited by 211
Health-Related Quality of Life in patients with Parkinson's disease—A systematic review based on the ICF model
van Uem, J. M. T., Marinus, J., Canning, C. G., van Lummel, R. C., Dodel, R. C., Liepelt‐Scarfone, I., Berg, D., Morris, M. E., & Maetzler, W. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.11.014 · Cited by 218
Depression and anxiety related subtypes in Parkinson's disease
Brown, R. G., Landau, S., Hindle, J. V., Playfer, J., Samuel, M., Wilson, K. C., Hurt, C. S., Anderson, R. J., Carnell, J., Dickinson, L., et al. (2011) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.2010.213652 · Cited by 183
Depression, anxiety, and apathy in Parkinson's disease: insights from neuroimaging studies
Wen, M., Chan, L. L., Tan, L. C. S., & Tan, E. (2016) · European Journal of Neurology · doi:10.1111/ene.13002 · Cited by 196
Symptomatology and markers of anxiety disorders in Parkinson's disease: A cross‐sectional study
Leentjens, A. F. G., Dujardin, K., Marsh, L., Martinez‐Martin, P., Richard, I. H., & Starkstein, S. E. (2011) · Movement Disorders · doi:10.1002/mds.23528 · Cited by 173
Self-citation
Depression in Patients with Parkinson’s Disease: Current Understanding of its Neurobiology and Implications for Treatment
Prange, S., Klinger, H., Laurencin, C., Danaila, T., & Thobois, S. (2022) · Drugs & Aging · doi:10.1007/s40266-022-00942-1 · Cited by 193
The Neuropsychiatry of Parkinson Disease: A Perfect Storm
Weintraub, D. A., & Mamikonyan, E. (2019) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2019.03.002 · Cited by 172
Exercise and Parkinson's disease
Xu, X., Fu, Z., & Le, W. (2019) · International Review of Neurobiology · doi:10.1016/bs.irn.2019.06.003 · Cited by 158
Parkinson's disease motor subtypes and mood
Burn, D. J., Landau, S., Hindle, J. V., Samuel, M., Wilson, K., Hurt, C. S., Brown, R. G., & for the PROMS‐PD Study Group (2011) · Movement Disorders · doi:10.1002/mds.24041 · Cited by 149
Awareness and current knowledge of Parkinson’s disease: a neurodegenerative disorder
Khan, A. U., Akram, M., Daniyal, M., & Zainab, R. (2018) · International Journal of Neuroscience · doi:10.1080/00207454.2018.1486837 · Cited by 151
The T herapeutic P otential of E xercise to I mprove M ood, C ognition, and S l eep in P arkinson's D isease
Reynolds, G., Otto, M. W., Ellis, T. D., & Cronin‐Golomb, A. (2015) · Movement Disorders · doi:10.1002/mds.26484 · Cited by 144
Potential mechanisms underlying anxiety and depression in Parkinson's disease: Consequences of l-DOPA treatment
Jaunarajs, K. L. E., Angoa‐Pérez, M., Kuhn, D. M., & Bishop, C. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.06.007 · Cited by 129
Systematic review of factors associated with depression and anxiety disorders among older adults with Parkinson's disease
Main, A. S. D., Gallo, J. J., & Pontone, G. M. (2014) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2014.03.020 · Cited by 129
Self-citation
Prevalence of malnutrition in Parkinson's disease: a systematic review
Sheard, J. M., Ash, S., Silburn, P. A., & Kerr, G. (2011) · Nutrition Reviews · doi:10.1111/j.1753-4887.2011.00413.x · Cited by 139
The clinical spectrum of anxiety in Parkinson's disease
Dissanayaka, N. N. N. W., White, E., O'Sullivan, J. D., Marsh, R., Pachana, N. A., & Byrne, G. J. (2014) · Movement Disorders · doi:10.1002/mds.25937 · Cited by 124
Parkinson’s Disease as a Disconnection Syndrome
Cronin‐Golomb, A. (2010) · Neuropsychology Review · doi:10.1007/s11065-010-9128-8 · Cited by 124
Frequency of mood and anxiety fluctuations in Parkinson's disease patients with motor fluctuations: A systematic review
van der Velden, R. M. J., Broen, M. P. G., Kuijf, M. L., & Leentjens, A. F. G. (2018) · Movement Disorders · doi:10.1002/mds.27465 · Cited by 118
Psychiatric aspects of Parkinson’s disease
Grover, S., Somaiya, M. P., Kumar, S., & Avasthi, A. (2014) · Journal of Neurosciences in Rural Practice · doi:10.4103/0976-3147.143197 · Cited by 116
Dance for PD: a preliminary investigation of effects on motor function and quality of life among persons with Parkinson’s disease (PD)
Westheimer, O., McRae, C., Henchcliffe, C., Fesharaki‐Zadeh, A., Glazman, S., Ene, H., & Bodis-Wollner, I. G. (2015) · Journal of Neural Transmission · doi:10.1007/s00702-015-1380-x · Cited by 115
The effect of resistance training on the anxiety symptoms and quality of life in elderly people with Parkinson's disease: a randomized controlled trial
Ferreira, R. M., Alves, W. M. G. D. C., de Lima, T. A., Alves, T. G. G., Filho, P. A. M. A., Pimentel, C. P., de Sousa, E. C., & Cortinhas‐Alves, E. A. (2018) · Arquivos de Neuro-Psiquiatria · doi:10.1590/0004-282x20180071 · Cited by 130
International validation of a behavioral scale in Parkinson's disease without dementia
Rieu, I., Martínez‐Martín, P., Pereira, B., de Chazeron, I., Metman, L. V., Jahanshahi, M., Ardouin, C., Chéreau, I., Brefel‐Courbon, C., Ory‐Magne, F., et al. (2015) · Movement Disorders · doi:10.1002/mds.26223 · Cited by 112
Neurobiology of Depression and Anxiety in Parkinson's Disease
Kano, O., Ikeda, K., Cridebring, D., Takazawa, T., Yoshii, Y., & Iwasaki, Y. (2011) · Parkinson s Disease · doi:10.4061/2011/143547 · Cited by 107
Emotional manifestations of PD: Neurobiological basis
Castrioto, A., Thobois, S., Carnicella, S., Maillet, A., & Krack, P. (2016) · Movement Disorders · doi:10.1002/mds.26587 · Cited by 105
Neuroimaging Markers of Motor and Nonmotor Features of Parkinson's Disease: An [18F]Fluorodeoxyglucose Positron Emission Computed Tomography Study
Huang, C. C., Ravdin, L., Nirenberg, M. J., Piboolnurak, P., Severt, L., Maniscalco, J. S., Sólnes, L. B., Dorfman, B. J., & Henchcliffe, C. (2013) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000345987 · Cited by 105
Anxiety and motor fluctuations in Parkinson's disease: A cross-sectional observational study
Leentjens, A. F. G., Dujardin, K., Marsh, L., Martínez‐Martín, P., Richard, I., & STARKSTEIN, S. E. (2012) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2012.06.007 · Cited by 97
Self-citation
Connectivity and Functionality of the Globus Pallidus Externa Under Normal Conditions and Parkinson's Disease
Dong, J., Hawes, S., Wu, J., Le, W., & Cai, H. (2021) · Frontiers in Neural Circuits · doi:10.3389/fncir.2021.645287 · Cited by 93
Management of psychiatric and cognitive complications in Parkinson’s disease
Weintraub, D. A., Aarsland, D., Biundo, R., Dobkin, R. D., Goldman, J. G., & Lewis, S. J. G. (2022) · BMJ · doi:10.1136/bmj-2021-068718 · Cited by 91
Anxiety is associated with freezing of gait and attentional set-shifting in Parkinson’s disease: A new perspective for early intervention
Martens, K. A. E., Hall, J. M., Gilat, M., Georgiades, M., Walton, C. C., & Lewis, S. J. G. (2016) · Gait & Posture · doi:10.1016/j.gaitpost.2016.07.182 · Cited by 90
Impact of Anxiety on Quality of Life in Parkinson's Disease
Hanna, K. K., & Cronin‐Golomb, A. (2011) · Parkinson s Disease · doi:10.1155/2012/640707 · Cited by 95
Epigenome-Wide Association Study for Parkinson’s Disease
Moore, K., McKnight, A. J., Craig, D., & O’Neill, F. A. (2014) · NeuroMolecular Medicine · doi:10.1007/s12017-014-8332-8 · Cited by 87
Methanolic extract of Hibiscus asper leaves improves spatial memory deficits in the 6-hydroxydopamine-lesion rodent model of Parkinson's disease
Foyet, H. S., Hriţcu, L., Ciobica, A. S., Ștefan, M., Kamtchouing, P., & Cojocaru, D. (2010) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2010.11.011 · Cited by 84
Emotional dysfunction in Parkinson's disease.
Blonder, L. X., & Slevin, J. T. (2011) · PubMed Central · doi:10.3233/ben-2011-0329 · Cited by 86
Neuroprotective Potency of Saffron Against Neuropsychiatric Diseases, Neurodegenerative Diseases, and Other Brain Disorders: From Bench to Bedside
Bian, Y., Zhao, C., & Lee, S. M. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.579052 · Cited by 86
Psychological Benefits of Nonpharmacological Methods Aimed for Improving Balance in Parkinson’s Disease: A Systematic Review
Šumec, R., Filip, P., Sheardová, K., & Bareš, M. (2015) · Behavioural Neurology · doi:10.1155/2015/620674 · Cited by 82
Melatoninergic System in Parkinson’s Disease: From Neuroprotection to the Management of Motor and Nonmotor Symptoms
Mack, J. M., Schamne, M. G., Sampaio, T. B., Pértile, R. A. N., Fernandes, P. A. C. M., Markus, R. P., & Prediger, R. D. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/3472032 · Cited by 81
Emotional Dysfunction in Parkinson’s Disease
Blonder, L. X., & Slevin, J. T. (2011) · Behavioural Neurology · doi:10.1155/2011/143857 · Cited by 91
Effects of dance therapy on cognitive and mood symptoms in people with Parkinson's disease: A systematic review and meta-analysis
Zhang, Q., Hu, J., Wei, L., Jia, Y., & Jin, Y. (2019) · Complementary Therapies in Clinical Practice · doi:10.1016/j.ctcp.2019.04.005 · Cited by 80
A Pilot Study of a Cognitive–Behavioral Treatment for Anxiety and Depression in Patients With Parkinson Disease
Calleo, J. S., Amspoker, A. B., Sarwar, A. I., Kunik, M. E., Jankovic, J., Marsh, L., York, M., & Stanley, M. A. (2015) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988715588831 · Cited by 71
Self-citation
Mood disorders in Parkinson's disease
Tan, L. C. S. (2011) · Parkinsonism & Related Disorders · doi:10.1016/s1353-8020(11)70024-4 · Cited by 70
Anxiety in Parkinson's disease: Symptom dimensions and overlap with depression and autonomic failure
Rutten, S., Ghielen, I., Vriend, C., Hoogendoorn, A. W., Berendse, H. W., Leentjens, A. F. G., van der Werf, Y. D., Smit, J. H., & van den Heuvel, O. A. (2015) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2014.11.019 · Cited by 73
Anxiety and self-perceived health status in Parkinson’s disease
Pontone, G. M., Williams, J. R., Anderson, K. E., Chase, G. A., Goldstein, S. R., Grill, S. E., Hirsch, E. S., Lehmann, S. W., Little, J. T., Margolis, R. L., et al. (2011) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2011.01.005 · Cited by 72
Self-citation
Exercise as a therapeutic intervention for motor and non-motor symptoms in Parkinson’s disease: Evidence from rodent models
Crowley, E. K., Nolan, Y. M., & Sullivan, A. M. (2018) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2018.11.003 · Cited by 72
Depression and anxiety in Parkinson disease
Martínez‐Martín, P., & Damián, J. (2010) · Nature Reviews Neurology · doi:10.1038/nrneurol.2010.49 · Cited by 64
Report from a multidisciplinary meeting on anxiety as a non-motor manifestation of Parkinson’s disease
Pontone, G. M., Dissanayaka, N. N., Apostolova, L. G., Brown, R. G., Dobkin, R. D., Dujardin, K., Friedman, J. H., Leentjens, A. F. G., Lenze, E. J., Marsh, L., et al. (2019) · npj Parkinson s Disease · doi:10.1038/s41531-019-0102-8 · Cited by 71
Self-citation
Affective symptoms and cognitive functions in Parkinson's disease
Poletti, M., Rosa, A. D., & Bonuccelli, U. (2012) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2012.02.022 · Cited by 62
A meta-analysis of third wave mindfulness-based cognitive behavioral therapies for older people
Kishita, N., Takei, Y., & Stewart, I. (2017) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.4621 · Cited by 60
Disease-specific anxiety symptomatology in Parkinson's disease
Dissanayaka, N. N., O’Sullivan, J. D., Pachana, N. A., Marsh, R., Silburn, P. A., White, E., Torbey, E., Mellick, G. D., Copland, D. A., & Byrne, G. J. (2016) · International Psychogeriatrics · doi:10.1017/s1041610215002410 · Cited by 59
Validity and reliability of the Geriatric Anxiety Inventory in Parkinson's disease*†
Matheson, S., Byrne, G. J., Dissanayaka, N. N., Pachana, N. A., Mellick, G. D., O’Sullivan, J. D., Silburn, P. A., Sellbach, A. N., & Marsh, R. (2010) · Australian Journal on Ageing · doi:10.1111/j.1741-6612.2010.00487.x · Cited by 58
Neuropsychiatric Predictors of Cognitive Decline in Parkinson Disease: A Longitudinal Study
Pirogovsky‐Turk, E., Moore, R. C., Filoteo, J. V., Litvan, I., Song, D. D., Lessig, S. L., & Schiehser, D. M. (2016) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2016.10.004 · Cited by 65
Subjective Cognitive Complaint in Parkinson's Disease Patients With Normal Cognition: Canary in the Coal Mine?
Purri, R., Brennan, L., Rick, J. H., Xie, S. X., Deck, B. L., Chahine, L. M., Dahodwala, N. A., Chen‐Plotkin, A. S., Duda, J. E., Morley, J. F., et al. (2020) · Movement Disorders · doi:10.1002/mds.28115 · Cited by 62
Degeneration of dopaminergic circuitry influences depressive symptoms in Lewy body disorders
Patterson, L., Rushton, S., Attems, J., Thomas, A. J., & Morris, C. M. (2018) · Brain Pathology · doi:10.1111/bpa.12697 · Cited by 53
Anxiety Disorders: Differential Diagnosis and Their Relationship to Chronic Pain
Jordan, K. D., & Okifuji, A. (2011) · Journal of Pain & Palliative Care Pharmacotherapy · doi:10.3109/15360288.2011.596922 · Cited by 51
Neuropsychiatric Disorders in Parkinson’s Disease: What Do We Know About the Role of Dopaminergic and Non-dopaminergic Systems?
Dujardin, K., & Sgambato, V. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00025 · Cited by 46
Increased dopamine transporter density in Parkinson's disease patients with social anxiety disorder
Moriyama, T. S., Felicio, A. C., Chagas, M. H. N., Tardelli, V. S., Ferraz, H. B., Tumas, V., Amaro, E., Andrade, L. E. C., Crippa, J. A. S., & Bressan, R. A. (2011) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2011.06.056 · Cited by 50
Revisiting Preclinical Observations of Several Histamine H3 Receptor Antagonists/Inverse Agonists in Cognitive Impairment, Anxiety, Depression, and Sleep–Wake Cycle Disorder
Alhusaini, M., Eissa, N., Saad, A. K., Beiram, R., & Sadek, B. S. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.861094 · Cited by 51
Metabotropic Glutamate Receptors in Central Nervous System Diseases
Golubeva, A. V., Moloney, R. D., O’Connor, R. M., Dinan, T. G., & Cryan, J. F. (2016) · Current Drug Targets · doi:10.2174/1389450116666150316224011 · Cited by 51
Eplingiella fruticosa leaf essential oil complexed with β-cyclodextrin produces a superior neuroprotective and behavioral profile in a mice model of Parkinson's disease
Beserra‐Filho, J. I. A., Macedo, A. M. D. [., Leão, A. H. F. F., Bispo, J. M. M., dos Santos, J. R., Melo, A. J. D. O., Menezes, P. D. P., Duarte, M. C., Araújo, A. A. D. S., Silva, R. H., et al. (2018) · Food and Chemical Toxicology · doi:10.1016/j.fct.2018.11.056 · Cited by 49
Anxiety and Depression in Parkinson’s Disease
Djamshidian, A., & Friedman, J. H. (2014) · Current Treatment Options in Neurology · doi:10.1007/s11940-014-0285-6 · Cited by 47
Neuropsychiatric symptoms in untreated Parkinson’s disease
Szatmári, S., Illigens, B. M. W., Siepmann, T., Pintér, A., Takáts, A., & Bereczki, D. (2017) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s130997 · Cited by 47
The Effect of Different Exercise Modes on Domain-Specific Cognitive Function in Patients Suffering from Parkinson’s Disease: A Systematic Review of Randomized Controlled Trials
Stuckenschneider, T., Askew, C. D., Menêses, A. L., Baake, R., Weber, J., & Schneider, S. (2019) · Journal of Parkinson s Disease · doi:10.3233/jpd-181484 · Cited by 48
The relation of anxiety and cognition in Parkinson’s disease.
Reynolds, G., Hanna, K. K., Neargarder, S. A., & Cronin‐Golomb, A. (2017) · Neuropsychology · doi:10.1037/neu0000353 · Cited by 44
Clinical Markers of Anxiety Subtypes in Parkinson Disease
Broen, M. P. G., Leentjens, A. F. G., Hinkle, J. T., Moonen, A. J. H., Kuijf, M. L., Fischer, N. M., Perepezko, K. M., Bakker, A., & Pontone, G. M. (2018) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988718757369 · Cited by 48
Self-citation
Neurocognitive Correlates of Apathy and Anxiety in Parkinson's Disease
Bogdanova, Y., & Cronin‐Golomb, A. (2011) · Parkinson s Disease · doi:10.1155/2012/793076 · Cited by 43
Nonmotor Fluctuations in Parkinson's Disease.
Franke, C., & Storch, A. (2017) · International review of neurobiology · doi:10.1016/bs.irn.2017.05.021 · Cited by 54
Anxiety Has Specific Syndromal Profiles in Parkinson Disease: A Data-Driven Approach
STARKSTEIN, S. E., Dragović, M., Dujardin, K., Marsh, L., Martínez‐Martín, P., Pontone, G. M., Richard, I. H., Weintraub, D. A., & Leentjens, A. F. G. (2013) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2013.09.006 · Cited by 41
Self-citation
Non-motor symptoms in Parkinson's disease: Opening new avenues in treatment
Gupta, S., & Shukla, S. (2021) · Current Research in Behavioral Sciences · doi:10.1016/j.crbeha.2021.100049 · Cited by 41
Management of psychiatric disorders in Parkinson's disease
Weintraub, D. A. (2020) · Neurotherapeutics · doi:10.1007/s13311-020-00875-w · Cited by 42
Characteristics and Treatment of Anxiety Disorders in Parkinson's Disease
Dissanayaka, N. N., White, E., O’Sullivan, J. D., Marsh, R., Silburn, P. A., Copland, D. A., Mellick, G. D., & Byrne, G. J. (2015) · Movement Disorders Clinical Practice · doi:10.1002/mdc3.12157 · Cited by 39
Anxiety Disorders, Physical Illnesses, and Health Care Utilization in Older Male Veterans With Parkinson Disease and Comorbid Depression
Qureshi, S. U., Amspoker, A. B., Calleo, J., Kunik, M. E., & Marsh, L. (2012) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988712466458 · Cited by 39
Self-citation
Cognitive Behavioral Therapy for Depression and Anxiety in Parkinson's Disease: A Clinical Review
Armento, M. E. A., Stanley, M. A., Marsh, L., Kunik, M. E., York, M. K., Bush, A. L., & Calleo, J. S. (2012) · Journal of Parkinson's Disease · doi:10.3233/jpd-2012-12080 · Cited by 49
Self-citation
Depressive symptoms precede cognitive impairment in de novo Parkinson’s disease patients: Analysis of the PPMI cohort.
Jones, J. D., Kurniadi, N. E., Kuhn, T. P., Szymkowicz, S. M., Bunch, J., & Rahmani, E. (2019) · Neuropsychology · doi:10.1037/neu0000583 · Cited by 38
Molecular imaging of neuropsychiatric symptoms in Alzheimer's and Parkinson's disease
Hirao, K., Pontone, G. M., & Smith, G. S. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.11.010 · Cited by 38
Self-citation
Screening for Anxiety Symptoms in Parkinson Disease
Stefanova, E. D., Žiropadja, L., Petrovic, M. J., Stojković, T., & Kostić, V. (2013) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988713476368 · Cited by 37
Neuropsychiatric and Cognitive Deficits in Parkinson’s Disease and Their Modeling in Rodents
Decourt, M., Jiménez‐Urbieta, H., Benoit‐Marand, M., & Fernagut, P. (2021) · Biomedicines · doi:10.3390/biomedicines9060684 · Cited by 37
Neuropsychiatric Complications of Parkinson Disease Treatments: Importance of Multidisciplinary Care
Taylor, J., Anderson, W. S., Brandt, J., Mari, Z. K., & Pontone, G. M. (2016) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2016.08.017 · Cited by 36
Self-citation
Ages at Onset of Anxiety and Depressive Disorders in Parkinson’s Disease
Seritan, A. L., Rienas, C., Duong, T., Delucchi, K., & Ostrem, J. L. (2019) · Journal of Neuropsychiatry · doi:10.1176/appi.neuropsych.18090201 · Cited by 39
Pharmacologic Treatment of Anxiety Disorders in Parkinson Disease
Pontone, G. M., Williams, J. R., Anderson, K. E., Chase, G. A., Goldstein, S. R., Grill, S. E., Hirsch, E. S., Lehmann, S. W., Little, J. T., Margolis, R. L., et al. (2013) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2012.10.023 · Cited by 36
Self-citation
Neural correlates of anxiety symptoms in mild Parkinson's disease: A prospective longitudinal voxel-based morphometry study
van der Wee, N. J. A., Wen, M., Kandiah, N., Chander, R. J., Ng, A. Y. T., Au, W. L., & Tan, L. C. S. (2016) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2016.10.021 · Cited by 35
Detecting anxiety in individuals with Parkinson disease
Mele, B., Holroyd-Leduc, J. M., Smith, E. E., Pringsheim, T. M., Ismail, Z., & Goodarzi, Z. (2017) · Neurology · doi:10.1212/wnl.0000000000004771 · Cited by 36
Anxiety in early Parkinson's disease: Validation of the Italian observer-rated version of the Parkinson Anxiety Scale (OR-PAS)
Santangelo, G., Falco, F., D’Iorio, A., Cuoco, S., Raimo, S., Amboni, M., Pellecchia, M. T., Longo, K., Vitale, C., & Barone, P. (2016) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2016.06.008 · Cited by 34
Psychiatric symptoms screening in the early stages of Parkinson’s disease
Bugalho, P., da Silva, J. A., Cargaleiro, I., Serra, M., & Neto, B. M. (2011) · Journal of Neurology · doi:10.1007/s00415-011-6140-8 · Cited by 32
Evaluating psychiatric symptoms in Parkinson's Disease by a clinimetric analysis of the Hopkins Symptom Checklist (SCL‐90‐R)
Carrozzino, D., Morberg, B. M., Siri, C., Pezzoli, G., & Bech, P. (2018) · Progress in Neuro-psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.10.024 · Cited by 40
‘Anxious fluctuators’ a subgroup of Parkinson's disease with high anxiety and problematic on-off fluctuations
Pontone, G. M., Perepezko, K. M., Hinkle, J. T., Gallo, J. J., Grill, S. E., Leoutsakos, J., Mills, K. A., Weiss, H. D., & Mari, Z. K. (2022) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2022.11.002 · Cited by 31
Self-citation
Measuring Anxiety in Patients With Early-Stage Parkinson's Disease: Rasch Analysis of the State-Trait Anxiety Inventory
Yang, H.-J., Ahn, J., Lee, J. S., Lee, W. K., Lee, J., & Kim, Y. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.00049 · Cited by 30
Modeling anxiety in Parkinson's disease
Broen, M. P. G., Köhler, S., Moonen, A. J. H., Kuijf, M. L., Dujardin, K., Marsh, L., Richard, I. H., STARKSTEIN, S. E., Martínez‐Martín, P., & Leentjens, A. F. G. (2015) · Movement Disorders · doi:10.1002/mds.26461 · Cited by 31
Self-citation
Non-Motor Fluctuations in Parkinson’s Disease: Underdiagnosed Yet Important
Boura, I., Popławska-Domaszewicz, K., Spanaki, C., Chen, R., Urso, D., van Coller, R., Storch, A., & Chaudhuri, К. R. (2024) · Journal of Movement Disorders · doi:10.14802/jmd.24227 · Cited by 30
Freezing of Gait and its Associations in the Early and Advanced Clinical Motor Stages of Parkinson’s Disease: A Cross-Sectional Study
Hall, J. M., Shine, J. M., O’Callaghan, C., Walton, C. C., Gilat, M., Naismith, S. L., & Lewis, S. J. G. (2015) · Journal of Parkinson s Disease · doi:10.3233/jpd-150581 · Cited by 30
Rasch analysis of anxiety scales in Parkinson's disease
Forjaz, M. J., Martínez‐Martín, P., Dujardin, K., Marsh, L., Richard, I. H., STARKSTEIN, S. E., & Leentjens, A. F. G. (2013) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2013.02.009 · Cited by 30
Self-citation
Association of restless legs syndrome, pain, and mood disorders in parkinson's disease
Rana, A. Q., Qureshi, A. R., Rahman, L., Jesudasan, A., Hafez, K. K., & Rana, M. A. (2014) · International Journal of Neuroscience · doi:10.3109/00207454.2014.994208 · Cited by 29
A clinical overview of non-motor symptoms in Parkinson's Disease.
Modugno, N., Lena, F., Biasio, F. D., Cerrone, G., Ruggieri, S. A., & Fornai, F. (2013) · PubMed · Cited by 27
Quantification of brainstem norepinephrine relative to vocal impairment and anxiety in the Pink1-/- rat model of Parkinson disease
Hoffmeister, J. D., Kelm‐Nelson, C. A., & Ciucci, M. R. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113514 · Cited by 28
Basal ganglia oscillations as biomarkers for targeting circuit dysfunction in Parkinson's disease
Petersson, P., Kühn, A. A., Neumann, W., & Fuentes, R. (2020) · Progress in brain research · doi:10.1016/bs.pbr.2020.02.002 · Cited by 27
Neurocognitive Psychiatric and Neuropsychological Alterations in Parkinson’s Disease: A Basic and Clinical Approach
González-Usigli, H., Ortíz, G. G., Niño, C. L. C., Mireles-Ramírez, M. A., Pacheco-Moisés, F. P., Torres-Mendoza, B. M., Hernández-Cruz, J. J., Delgado-Lara, D. L. C., & Ramírez-Jirano, L. J. (2023) · Brain Sciences · doi:10.3390/brainsci13030508 · Cited by 28

Authors: Pontone, G. M., Williams, J. R., Anderson, K. E., Chase, G., Goldstein, S. A., Grill, S., Hirsch, E. S., Lehmann, S., Little, J. T., Margolis, R. L., Rabins, P. V., Weiss, H. D., & Marsh, L.
Affiliations: Johns Hopkins University (US)
University of Maryland Medical Center (US)
Pennsylvania State University (US)
Corresponding author: Marsh, Laura
ORCID: Pontone, Gregory M.
Williams, James R.
Anderson, Karen E.
Grill, Stephen
Margolis, Russell L.
Marsh, Laura
Venue: Movement Disorders
Publisher: Wiley
Published: 2009-05-07
Volume: 24
Issue: 9
Pages: 1333-1338
ISSN: 0885-3185 (ISSN-L)
1531-8257
DOI: 10.1002/mds.22611
PMC: PMC2830642
OpenAlex: W2121594879
Cited by: 305
References: 41
Citations by year: 2026: 11 · 2025: 14 · 2024: 8 · 2023: 9 · 2022: 15 · 2021: 19 · 2020: 45 · 2019: 20 · 2018: 15 · 2017: 11 · 2016: 27 · 2015: 14 · 2014: 22 · 2013: 25 · 2012: 14
FWCI: 10.64
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Movement Disorders (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: NIH (R01-MH069666)
Morris K. Udall Parkinson's Disease Research Center of Excellence at Johns Hopkins (NIH-P50-NS-58377)
Age-Related Cognitive Disorders Training Grant (NIH-5T32-AG-027668-02)
Parkinson Study Group Mentored Clinical Research Award
Donna Jeanne Gault Baumann Fund
Topics: Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords: Parkinson's disease, anxiety disorders, prevalence, panic disorder, anxiety subtypes, motor fluctuations, age of onset, psychiatric comorbidity, underdiagnosis
MeSH terms: Aged, Aged, 80 and over, Anxiety, Anxiety Disorders, Female, Humans, Male, Middle Aged, Parkinson Disease, Prevalence, Panic Disorder

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Prevalence of anxiety disorders and anxiety subtypes in patients with Parkinson's disease

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks