The DOI matches its Crossref record; 40 of the 41 references it cites were found in a registry or an index.
Prevalence of anxiety disorders and anxiety subtypes in patients with Parkinson's disease
Open accessAbstract
Anxiety disorders are common in Parkinson's disease (PD), but are not well characterized. This study determined the prevalence and clinical correlates of all DSM‐IV‐TR anxiety disorder diagnoses in a sample of 127 subjects with idiopathic PD who underwent comprehensive assessments administered by a psychiatrist and neurologist. A panel of six psychiatrists with expertise in geriatric psychiatry and/or movement disorders established by consensus all psychiatric diagnoses. Current and lifetime prevalence of at least one anxiety disorder diagnosis was 43% (n = 55) and 49% (n = 63), respectively. Anxiety disorder not otherwise specified, a DSM diagnosis used for anxiety disturbances not meeting criteria for defined subtypes, was the most common diagnosis (30% lifetime prevalence, n = 38). Compared with nonanxious subjects, panic disorder (n = 13) was associated with earlier age of PD onset [50.3 (12.2) vs. 61.0 (13.7) years, P < 0.01], higher rates of motor fluctuations [77% (10/13) vs. 39% (25/64), P = 0.01] and morning dystonia [38% (5/13) vs. 13% (8/62), P < 0.03]. This high prevalence of anxiety disorders, including disturbances often not meeting conventional diagnostic criteria, suggests that anxiety in PD is likely underdiagnosed and undertreated and refined characterization of anxiety disorders in PD is needed. In addition, certain anxiety subtypes may be clinically useful markers associated with disease impact in PD. © 2009 Movement Disorder Society
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“Anxiety and depression are common non-motor symptoms of Parkinson’s disease (PD).”
From Online Mindfulness-Based Cognitive Therapy for People with Parkinson’s Disease and Their Caregivers: a Pilot Study (2022) · cites this paper as Pontone et al., 2009
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- First MB, 2002, Structured clinical interview for DSM‐IV‐TR axis I disorders, research version, patient edition. (SCID‐I/P). Biometrics Research 2002
- 10.1176/appi.neuropsych.18.1.130 · DOI
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Elcadi, K., Rhazouani, O. C., Louhab, N., Kissani, N., & Chraa, M. (2026) · Diseases · doi:10.3390/diseases14090338
He, G., Wang, G., Haihua, S., Wang, S., Chen, X., Liu, W., & Pan, P. (2026) · Frontiers in Neuroscience · doi:10.3389/fnins.2026.1955684
Elahi, B. (2026) · Progress in brain research · doi:10.1016/bs.pbr.2026.10.003
Metadata
- Authors
- Pontone, G. M., Williams, J. R., Anderson, K. E., Chase, G., Goldstein, S. A., Grill, S., Hirsch, E. S., Lehmann, S., Little, J. T., Margolis, R. L., Rabins, P. V., Weiss, H. D., & Marsh, L.
- Affiliations
- Johns Hopkins University (US)
- University of Maryland Medical Center (US)
- Pennsylvania State University (US)
- Corresponding author
- Marsh, Laura
- ORCID
- Venue
- Movement Disorders
- Publisher
- Wiley
- Published
- 2009-05-07
- Volume
- 24
- Issue
- 9
- Pages
- 1333-1338
- ISSN
- 0885-3185 (ISSN-L)
- 1531-8257
- PMC
- PMC2830642
- OpenAlex
- W2121594879
- Cited by
- 305
- References
- 41
- Citations by year
- 2026: 11 · 2025: 14 · 2024: 8 · 2023: 9 · 2022: 15 · 2021: 19 · 2020: 45 · 2019: 20 · 2018: 15 · 2017: 11 · 2016: 27 · 2015: 14 · 2014: 22 · 2013: 25 · 2012: 14
- FWCI
- 10.64
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Movement Disorders (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NIH (R01-MH069666)
- Morris K. Udall Parkinson's Disease Research Center of Excellence at Johns Hopkins (NIH-P50-NS-58377)
- Age-Related Cognitive Disorders Training Grant (NIH-5T32-AG-027668-02)
- Parkinson Study Group Mentored Clinical Research Award
- Donna Jeanne Gault Baumann Fund
- Topics
- Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
- Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- Parkinson's disease, anxiety disorders, prevalence, panic disorder, anxiety subtypes, motor fluctuations, age of onset, psychiatric comorbidity, underdiagnosis
- MeSH terms
- Aged, Aged, 80 and over, Anxiety, Anxiety Disorders, Female, Humans, Male, Middle Aged, Parkinson Disease, Prevalence, Panic Disorder
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