Online Mindfulness-Based Cognitive Therapy for People with Parkinson’s Disease and Their Caregivers: a Pilot Study
Open accessAbstract
Anxiety and depression are common non-motor symptoms of Parkinson’s disease (PD). Caregivers of people with PD may experience severe caregiver burden. This study explored the feasibility and potential benefits of an online mindfulness-based cognitive therapy (MBCT) intervention for improving anxiety and depressive symptoms in people with PD and their caregivers (ClinicalTrials.gov NCT04469049, 7/8/2020). People with PD or parkinsonism and anxiety and/or depressive symptoms and caregivers of people with PD participated in one of three online MBCT groups. Demographic variables, pre- and post-MBCT behavioral measures (GAD-7, PHQ-9, Five Facet Mindfulness Questionnaire — FFMQ-15, Caregiver Self-Assessment Questionnaire — CSAQ), and satisfaction surveys were collected. Descriptive statistics were used to summarize data. Pre- and post-MBCT behavioral scores were compared using mixed-effect models. Fifty-six potential participants were assessed for eligibility. Twenty-eight entered MBCT groups; all but one completed the intervention. The overall sample analyzed (22 people with PD, 4 caregivers) showed significant GAD-7 and PHQ-9 score reductions and FFMQ-15 total and observing and non-reactivity subscale score increases (all p’s < 0.05). Participants with PD and anxiety symptoms (n = 14) had a significant GAD-7 score reduction; those with PD and depressive symptoms (n = 12) had a significant PHQ-9 score reduction (both p’s < 0.05). Participants with PD also had a significant FFMQ-15 observing subscale score increase (p < 0.05). The caregiver sample was too small to be analyzed separately. Online MBCT is feasible (as measured by high attendance, completion rate, and participant satisfaction) and may be effective in improving anxiety and depressive symptoms in people with PD. © 2022, The Author(s), under exclusive licence to Springer Nature Switzerland AG.
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Cites
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Claims the paper makes
5 of 9 cited sources checked · 2 supported · 0 flagged · accuracy not yet measured
- Background
The paper states that caregivers of people with PD have not previously been studied with MBCT, to the authors' knowledge.
“MBCT has been used with family caregivers of patients with dementia, showing reduced stress, anxiety, depression, and distress related to the patients’ challenging behaviors (Chacko et al., 2022), but it has not been studied in caregivers of cognitively intact people with PD, to our knowledge.”
Quote in the paperNot yet classified1 of 1 sources checked- cites Chacko et al., 2022 source
- Method
Eligible participants had to be able and willing to attend eight weekly 90-minute online group sessions and have minimal-to-moderate anxiety or depressive symptoms.
“Inclusion criteria were having a diagnosis of PD or parkinsonism established by a neurologist or being a caregiver of a person with PD; being able and willing to attend eight weekly 90-min online group sessions; experiencing minimal-to-moderate anxiety symptoms (Generalized Anxiety Disorder-7 item scale — GAD-7 score ≤ 16) and/or minimal-to-moderate depressive symptoms (Patient Health Questionnaire-9 scale — PHQ-9 score ≤ 18)”
Quote in the paperNot yet classified1 of 2 sources checked- cites Kroenke et al., 2001 source
The Methods identify the PHQ-9 as a nine-item measure of depressive symptoms. The Results classify scores of 15–19 as moderately severe, so the cited paper does not support describing everyone with a PHQ-9 score ≤18 as having minimal-to-moderate depressive symptoms. The session requirement is the citing study’s own eligibility criterion, not a claim about the PHQ-9 paper. (LLM, conf=0.88)
Experimental — accuracy not yet measured - cites Löwe et al., 2008
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Background
The paper states that the COVID-19 pandemic made online MBIs feasible but their effectiveness was not yet fully established.
“Initial reports of online MBIs offered during the pandemic have underscored the feasibility of these interventions, although their effectiveness has not yet been fully established (Accoto et al., 2021; Kang et al., 2021; Nourian et al., 2021).”
Quote in the paperNot yet classified2 of 3 sources checked- cites Accoto et al., 2021 source
The Introduction and Methods §2.3 describe an MBSR course that continued online during Italy’s lockdown, supporting the feasibility of that adaptation. Discussion §4.5 cautions that the small, nonrandomized study cannot establish a causal treatment effect. But only the last two sessions were online, so the paper does not establish a general conclusion about the effectiveness of fully online MBIs. (LLM, conf=0.84)
Experimental — accuracy not yet measured - cites Kang et al., 2021 source
- cites Nourian et al., 2021 source
- Method
The protocol was adapted from an earlier MBCT protocol for people with PD by shortening sessions, removing mindful eating, and substituting chair yoga for full-body yoga.
“Modifications included shortening sessions from 2.5 h to 90 min in order to accommodate motor or non-motor (anxiety, attention, and mood changes) fluctuations; eliminating the mindful eating exercise (which could be perceived as insensitive by people with PD, who often have anosmia); and performing chair yoga instead of full body yoga.”
Quote in the paperNot yet classified1 of 3 sources checked- cites Segal et al., 2013
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Eisendrath et al., 2016 source
The Methods (Study Treatment Interventions; page unavailable) describe adapting MBCT for treatment-resistant depression, not Parkinson’s disease. They mention shorter meditations but do not describe 90-minute sessions, removal of mindful eating, or chair yoga. Searches for those modifications and PD found no supporting passage in our copy. (LLM, conf=0.78)
Experimental — accuracy not yet measured - cites Seritan et al., 2021 source
- Finding
The caregiver sample was too small to analyze separately.
“The caregiver sample was too small to be analyzed separately.”
Quote in the paperNot yet classified
- Finding
Most respondents reported satisfaction with the course and intended to continue mindfulness practice.
“Almost all (96%) of the participants who completed satisfaction surveys were satisfied or very satisfied with the course, 96% planned to continue to practice mindfulness, and all stated they would recommend MBCT to family or friends with PD.”
Quote in the paperNot yet classified - Finding
Participants with Parkinson's disease and depressive symptoms had significant improvement in depressive symptoms after MBCT.
“When restricting analyses further to people with PD and at least mild psychiatric symptoms, both the subsample with anxiety symptoms (n = 14, GAD-7 score ≥ 5) and the subgroup with depressive symptoms (n = 12, PHQ-9 score ≥ 5) demonstrated significant improvement (both p’s < 0.05).”
Quote in the paperNot yet classified - Finding
All four caregivers had improved CSAQ scores after MBCT.
“Individual CSAQ scores improved for all four caregivers.”
Quote in the paperNot yet classified - Finding
The intervention recruited 28 participants into MBCT groups, and all but one completed it.
“Twenty-eight entered MBCT groups; all but one completed the intervention.”
Quote in the paperNot yet classified - Finding
The overall analyzed sample showed significant reductions in anxiety and depression scores after MBCT.
“The overall analyzed sample had significant GAD-7 and PHQ-9 score reductions and significant FFMQ-15 total score and observing and non-reactivity subscale score increases (all p’s < 0.05).”
Quote in the paperNot yet classified - Finding
The authors argue that their findings suggest online MBCT may improve anxiety and depressive symptoms in people with Parkinson's disease.
“Online MBCT is feasible and may be effective in improving anxiety and depressive symptoms in people with PD.”
Quote in the paperNot yet classified - Finding
Participants with Parkinson's disease and anxiety symptoms had significant improvement in anxiety after MBCT.
“When restricting analyses further to people with PD and at least mild psychiatric symptoms, both the subsample with anxiety symptoms (n = 14, GAD-7 score ≥ 5) and the subgroup with depressive symptoms (n = 12, PHQ-9 score ≥ 5) demonstrated significant improvement (both p’s < 0.05).”
Quote in the paperNot yet classified - Finding
The study found online MBCT was feasible, based on recruitment, low attrition, high attendance, consistent home practice, and high participant satisfaction.
“Feasibility was demonstrated by the ability to recruit the target number of participants with PD, very low attrition rate (4%), high attendance (95% people with PD and 75% caregivers attended ≥ 7 sessions), consistent home practice (approximately 3 h/week, on average), and high/very high participant satisfaction (96%).”
Quote in the paperNot yet classified - Finding
Participants with Parkinson's disease showed a significant increase in the observing facet of mindfulness after MBCT.
“Participants with PD also had a significant FFMQ-15 observing subscale score increase (p < 0.05).”
Quote in the paperNot yet classified - Background
The authors conclude that future studies should use larger, more diverse samples and control groups.
“These results should be replicated in studies with larger, more diverse samples, and using control groups.”
Quote in the paperNot yet classified - Method
The study aimed to evaluate the feasibility of an online MBCT intervention for people with Parkinson's disease and their caregivers.
“This study aimed to evaluate the feasibility of an online MBCT intervention for people with PD and their caregivers.”
Quote in the paperNot yet classified - Background
The paper states that anxiety and depression are common non-motor symptoms of Parkinson's disease.
“Anxiety and depression are common non-motor symptoms of Parkinson’s disease (PD).”
Quote in the paperNot yet classified - Method
The MBCT groups were delivered online in Zoom during the COVID-19 pandemic.
“Group sessions were conducted in Zoom (https://zoom.us/).”
Quote in the paperNot yet classified - Method
The study was approved by the UCSF Institutional Review Board and registered on ClinicalTrials.gov.
“This study was approved by the Institutional Review Board at the University of California, San Francisco (UCSF) and registered on ClinicalTrials.gov (NCT04469049, 7/8/2020).”
Quote in the paperNot yet classified - Background
The paper states that caregivers of people with Parkinson's disease may experience severe caregiver burden.
“Caregivers of people with PD may experience severe caregiver burden.”
Quote in the paperNot yet classified - Method
People with PD and caregivers were recruited through clinics, support groups, and websites, and caregivers could also be recruited after their care partners entered the study.
“People with PD and self-reported anxiety and/or depressive symptoms and caregivers of people with PD were recruited through local neurology clinics, support groups, and websites (https://clinicaltrials.ucsf.edu and ClinicalTrials.gov). Caregivers were also recruited directly after their care partners entered the study.”
Quote in the paperNot yet classified
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
FFMQ-15 minimum total score is misstated
MinorThe questionnaire has 15 questions, each scored from 1 to 5. Its minimum total is therefore 15, not 5.
Reported 5 · recomputed 15
“The total score range is 5–75, with subscale scores from 1 to 15; higher scores indicate higher mindfulness levels.”
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Evans, S., Ferrando, S., Findler, M., Stowell, C., Smart, C., & Haglin, D. (2008) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2007.07.005 · Cited by 559 · cited 2× · see citing works
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BackgroundWeekly change in mindfulness and perceived stress in a mindfulness-based stress reduction program
Baer, R. A., Carmody, J., & Hunsinger, M. (2012) · Journal of Clinical Psychology · doi:10.1002/jclp.21865 · Cited by 546 · cited 2× · see citing works
“Pre- and post-MBCT behavioral measures, GAD-7, PHQ-9, and Five Facet Mindfulness Questionnaire-15 (FFMQ-15; Baer et al., 2012), were collected for all MBCT participants.”
MethodKuyken, W., Hayes, R., Barrett, B., Byng, R., Dalgleish, T., Kessler, D., Lewis, G., Watkins, E., Brejcha, C., Cardy, J., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(14)62222-4 · Cited by 527 · see citing works
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Pontone, G. M., Williams, J. R., Anderson, K. E., Chase, G., Goldstein, S. A., Grill, S., Hirsch, E. S., Lehmann, S., Little, J. T., Margolis, R. L., et al. (2009) · Movement Disorders · doi:10.1002/mds.22611 · Cited by 305 · see citing works
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BackgroundCaregiver Burden in Parkinson Disease: A Critical Review of Recent Literature
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BackgroundCOVID-19 and telepsychiatry: Early outpatient experiences and implications for the future
Chen, J. A., Chung, W.-J., Young, S. K., Tuttle, M. C., Collins, M. B., Darghouth, S. L., Longley, R., Levy, R., Razafsha, M., Kerner, J. C., et al. (2020) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2020.07.002 · Cited by 227 · cited 1× · see citing works
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Martinez-Martin, P., Rodriguez-Blazquez, C., Forjaz, M. J., Frades-Payo, B., Agüera-Ortiz, L., Weintraub, D., Riesco, A., Kurtis, M. M., & Chaudhuri, K. R. (2015) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2015.03.024 · Cited by 222 · cited 2× · see citing works
“1 3 main determinant of caregiver burden (Martinez-Martin et al., 2015).”
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Bawa, F. L. M., Mercer, S. W., Atherton, R. J., Clague, F., Keen, A., Scott, N. W., & Bond, C. M. (2015) · British Journal of General Practice · doi:10.3399/bjgp15x685297 · Cited by 197 · cited 1× · see citing works
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“(Segal et al., 2013; Eisendrath et al., 2016) for use with people with PD (Seritan et al.”
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“One question, “Would you recommend MBCT to family or friends with PD?” was adapted, with permission, from a survey used in the Remote Access to Care, Everywhere, for Parkinson’s Disease (RACE-PD) study (Dorsey et al., 2010).”
MethodThe Effect of the COVID-19 Pandemic on People with Parkinson’s Disease
Brown, E. G., Chahine, L. M., Goldman, S. M., Korell, M., Mann, E., Kinel, D. R., Arnedo, V., Marek, K. L., & Tanner, C. M. (2020) · Journal of Parkinson's Disease · doi:10.3233/jpd-202249 · Cited by 177 · cited 2× · see citing works
“The social isolation imposed by the COVID-19 pandemic greatly affected people with PD (Brown et al., 2020; van der Heide et al., 2020).”
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A qualitative analysis of mindfulness‐based cognitive therapy (MBCT) in Parkinson's disease
Fitzpatrick, L., Simpson, J., & Smith, A. (2010) · Psychology and Psychotherapy: Theory, Research and Practice · doi:10.1348/147608309x471514 · Cited by 136 · cited 3× · see citing works
“People with PD who participated in an MBCT group noted improved coping skills and appreciated the mutual support (Fitzpatrick et al., 2010).”
BackgroundResultvan der Heide, A., Meinders, M. J., Bloem, B. R., & Helmich, R. C. (2020) · Journal of Parkinson’s Disease · doi:10.3233/jpd-202251 · Cited by 126 · see citing works
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“Attrition rate in MBCT groups can be as high as 30% (Crane & Williams, 2010; Rodgers et al., 2019).”
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Coughlin, D. G., & Litvan, I. (2020) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2020.04.014 · Cited by 113 · cited 1× · see citing works
“We decided to include patients with parkinsonism because of the high prevalence of anxiety and mood manifestations in atypical parkinsonian syndromes such as PSP and DLB (Bono et al., 2021; Coughlin & Litvan, 2020; Tampi et al., 2019).”
BackgroundEpstein‐Lubow, G., Gaudiano, B. A., Hinckley, M., Salloway, S., & Miller, I. W. (2010) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2009.02701.x · Cited by 106 · cited 1× · see citing works
“The CSAQ has been compared to established screening measures of caregiver burden, stress, depression, and grief, although it has not been fully validated (Epstein-Lubow et al., 2010).”
MethodChin, B., Lindsay, E. K., Greco, C. M., Brown, K. W., Smyth, J. M., Wright, A. G. C., & Creswell, J. D. (2019) · Health Psychology · doi:10.1037/hea0000763 · Cited by 103 · see citing works
The Effectiveness of Mindfulness-Based Cognitive Therapy (MBCT) in Real-World Healthcare Services
Tickell, A., Ball, S., Bernard, P., Kuyken, W., Marx, R., Pack, S., Strauss, C., Sweeney, T., & Crane, C. (2020) · Mindfulness · doi:10.1007/s12671-018-1087-9 · Cited by 99 · see citing works
Determinants of delayed diagnosis in Parkinson’s disease
Breen, D. P., Evans, J., Farrell, K., Brayne, C., & Barker, R. A. (2013) · Journal of Neurology · doi:10.1007/s00415-013-6905-3 · Cited by 94 · cited 1× · see citing works
“There can be early diagnostic uncertainty before idiopathic PD is confirmed, especially for patients presenting with gait abnormality or atypical features (Breen et al., 2013).”
BackgroundAdvocat, J., Enticott, J., Vandenberg, B., Hassed, C., Hester, J., & Russell, G. (2016) · BMC Neurology · doi:10.1186/s12883-016-0685-1 · Cited by 94 · cited 1× · see citing works
“An emerging body of evidence highlights the effectiveness of MBIs for people with PD, showing reduced anxiety and depressive symptoms and improvement in activities of daily living, cognitive functioning, motor symptoms, and general well-being, although studies were small and had mixed results (Advocat et al., 2016; Bi…”
BackgroundCash, T. V., Ekouevi, V. S., Kilbourn, C., & Lageman, S. K. (2016) · Mindfulness · doi:10.1007/s12671-015-0452-1 · Cited by 86 · cited 4× · see citing works
“An emerging body of evidence highlights the effectiveness of MBIs for people with PD, showing reduced anxiety and depressive symptoms and improvement in activities of daily living, cognitive functioning, motor symptoms, and general well-being, although studies were small and had mixed results (Advocat et al., 2016; Bi…”
BackgroundResultInfluentialSimpson, R., Simpson, S., Ramparsad, N., Lawrence, M., Booth, J., & Mercer, S. W. (2019) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp-2018-320165 · Cited by 86 · see citing works
Palliative Care and Parkinson's Disease: Caregiver Perspectives
Boersma, I., Jones, J., Coughlan, C., Carter, J., Bekelman, D., Miyasaki, J., Kutner, J., & Kluger, B. (2017) · Journal of Palliative Medicine · doi:10.1089/jpm.2016.0325 · Cited by 85 · cited 2× · see citing works
“Caregivers of people with PD experience mild-to-moderate caregiver burden, emotional difficulties, and disruption of their social lives (Boersma et al., 2017; Martinez-Martin et al., 2015; Mosley et al., 2017; Tolosa et al., 2021).”
BackgroundStress and mindfulness in Parkinson’s disease – a survey in 5000 patients
van der Heide, A., Speckens, A. E. M., Meinders, M. J., Rosenthal, L. S., Bloem, B. R., & Helmich, R. C. (2021) · npj Parkinson's Disease · doi:10.1038/s41531-020-00152-9 · Cited by 82 · see citing works
From State-to-Trait Meditation: Reconfiguration of Central Executive and Default Mode Networks
Bauer, C. C. C., Whitfield-Gabrieli, S., Díaz, J. L., Pasaye, E. H., & Barrios, F. A. (2019) · eneuro · doi:10.1523/eneuro.0335-18.2019 · Cited by 81 · cited 2× · see citing works
“Neuroimaging studies revealed reduced default mode network (DMN) activation and enhanced DMN-central executive network (CEN) connectivity in experienced meditators, suggesting that CEN negatively regulates the DMN (Bauer et al., 2019; Brewer et al., 2011; Garrison et al., 2015).”
BackgroundMindfulness Training among Individuals with Parkinson’s Disease: Neurobehavioral Effects
Pickut, B., Vanneste, S., Hirsch, M. A., Van Hecke, W., Kerckhofs, E., Mariën, P., Parizel, P. M., Crosiers, D., & Cras, P. (2015) · Parkinson's Disease · doi:10.1155/2015/816404 · Cited by 80 · see citing works
Stress and Mindfulness in Parkinson's Disease: Clinical Effects and Potential Underlying Mechanisms
van der Heide, A., Meinders, M. J., Speckens, A. E. M., Peerbolte, T. F., Bloem, B. R., & Helmich, R. C. (2021) · Movement Disorders · doi:10.1002/mds.28345 · Cited by 80 · see citing works
Mindfulness for Motor and Nonmotor Dysfunctions in Parkinson’s Disease
Dissanayaka, N. N. W., Idu Jion, F., Pachana, N. A., O’Sullivan, J. D., Marsh, R., Byrne, G. J., & Harnett, P. (2016) · Parkinson's Disease · doi:10.1155/2016/7109052 · Cited by 79 · cited 1× · see citing works
“Three previous MBI studies (Dissanayaka et al., 2016; Kwok et al., 2019; Pickut et al., 2015) also reported motor benefits, although only two (Kwok et al., 2019; Pickut et al., 2015) had significant results.”
Intervention Integrity in Mindfulness-Based Research
Crane, R. S., & Hecht, F. M. (2018) · Mindfulness · doi:10.1007/s12671-018-0886-3 · Cited by 75 · cited 1× · see citing works
“Adherence to protocol integrity is important in designing standardized interventions that can be broadly replicated (Crane & Hecht, 2018).”
BackgroundGhielen, I., Rutten, S., Boeschoten, R. E., Houniet-de Gier, M., van Wegen, E. E. H., van den Heuvel, O. A., & Cuijpers, P. (2019) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2019.05.001 · Cited by 74 · see citing works
Zarotti, N., Eccles, F. J. R., Foley, J. A., Paget, A., Gunn, S., Leroi, I., & Simpson, J. (2021) · Psychology and Psychotherapy Theory Research and Practice · doi:10.1111/papt.12321 · Cited by 73 · cited 1× · see citing works
“A recent review of psychological interventions for people with PD uncovered 56 studies, of which less than half (21) were randomized controlled trials (RCTs) (Zarotti et al., 2021).”
BackgroundFeasibility of Virtual Research Visits in Fox Trial Finder
Dorsey, E. R., Wagner, J. D., Bull, M. T., Rizzieri, A., Grischkan, J. A., Achey, M. A., Sherer, T., Chowdhury, S., Meunier, C. C., Cappelletti, L., et al. (2015) · Journal of Parkinson s Disease · doi:10.3233/jpd-150549 · Cited by 61 · cited 1× · see citing works
“Future studies should include standardized motor scales validated for online use to explore potential benefits of MBCT on motor symptoms (Dorsey et al., 2015).”
BackgroundHoogerwerf, A., Bol, Y., Lobbestael, J., Hupperts, R., & Heugten, C. (2017) · Journal of Rehabilitation Medicine · doi:10.2340/16501977-2237 · Cited by 58 · cited 1× · see citing works
“MBIs have also been studied in neurological diseases such as multiple sclerosis, demonstrating improvement in anxiety, depression, fatigue, and stress levels (Ghielen et al., 2019; Hoogerwerf et al., 2017; Simpson et al., 2019).”
BackgroundMarino, F., Failla, C., Carrozza, C., Ciminata, M., Chilà, P., Minutoli, R., Genovese, S., Puglisi, A., Arnao, A. A., Tartarisco, G., et al. (2021) · Brain Sciences · doi:10.3390/brainsci11060727 · Cited by 56 · see citing works
Bogosian, A., Hurt, C. S., Hindle, J. V., McCracken, L. M., Vasconcelos e Sa, D. A., Axell, S., Tapper, K., Stevens, J., Hirani, P. S., Salhab, M., et al. (2022) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988720988901 · Cited by 55 · see citing works
Nourian, M., Nikfarid, L., Khavari, A. M., Barati, M., & Allahgholipour, A. R. (2021) · Holistic Nursing Practice · doi:10.1097/hnp.0000000000000466 · Cited by 55 · see citing works
Effects of Mindfulness-Based Therapy for Cancer Patients: A Systematic Review and Meta-analysis
Lin, L., Lin, L., Tzeng, G.-L., Huang, Y.-H., Tai, J.-F., Chen, Y., Wu, C.-J., Chen, P.-H., Lin, P., & Hung, P. (2022) · Journal of Clinical Psychology in Medical Settings · doi:10.1007/s10880-022-09862-z · Cited by 52 · see citing works
Ghielen, I., van Wegen, E. E. H., Rutten, S., de Goede, C. J. T., Houniet-de Gier, M., Collette, E. H., Burgers-Bots, I. A. L., Twisk, J. W. R., Kwakkel, G., Vermunt, K., et al. (2017) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2017.09.008 · Cited by 50 · cited 1× · see citing works
“Other teams sought to improve awareness of motor symptoms by using mindfulness or a novel body awareness training (BEWARE) that combined physical therapy with acceptance and commitment therapy elements (Buchwitz et al., 2021; Ghielen et al., 2017).”
BackgroundBirtwell, K., Dubrow-Marshall, L., Dubrow-Marshall, R., Duerden, T., & Dunn, A. (2017) · Complementary Therapies in Clinical Practice · doi:10.1016/j.ctcp.2017.10.009 · Cited by 46 · cited 2× · see citing works
“An emerging body of evidence highlights the effectiveness of MBIs for people with PD, showing reduced anxiety and depressive symptoms and improvement in activities of daily living, cognitive functioning, motor symptoms, and general well-being, although studies were small and had mixed results (Advocat et al., 2016; Bi…”
BackgroundResultTelepsychiatry for patients with movement disorders: a feasibility and patient satisfaction study
Seritan, A. L., Heiry, M., Iosif, A., Dodge, M., & Ostrem, J. L. (2019) · Journal of Clinical Movement Disorders · doi:10.1186/s40734-019-0077-y · Cited by 46 · see citing works
Self-citationAccoto, A., Chiarella, S. G., Raffone, A., Montano, A., de Marco, A., Mainiero, F., Rubbino, R., Valzania, A., & Conversi, D. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18115512 · Cited by 44 · cited 1× · see citing works
“Initial reports of online MBIs offered during the pandemic have underscored the feasibility of these interventions, although their effectiveness has not yet been fully established (Accoto et al., 2021; Kang et al., 2021; Nourian et al., 2021).”
BackgroundRodgers, S. H., Schütze, R., Gasson, N., Anderson, R. A., Kane, R. T., Starkstein, S., Morgan-Lowes, K., & Egan, S. J. (2019) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s135246581800070x · Cited by 43 · see citing works
Ages at Onset of Anxiety and Depressive Disorders in Parkinson’s Disease
Seritan, A. L., Rienas, C., Duong, T., Delucchi, K., & Ostrem, J. L. (2019) · Journal of Neuropsychiatry · doi:10.1176/appi.neuropsych.18090201 · Cited by 36 · see citing works
Self-citationMoore, M. T., Lau, M. A., Haigh, E. A. P., Willett, B. R., Bosma, C. M., & Fresco, D. M. (2022) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000718 · Cited by 36 · see citing works
Chacko, E., Ling, B., Avny, N., Barak, Y., Cullum, S., Sundram, F., & Cheung, G. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19010614 · Cited by 34 · cited 1× · see citing works
“MBCT has been used with family caregivers of patients with dementia, showing reduced stress, anxiety, depression, and distress related to the patients’ challenging behaviors (Chacko et al., 2022), but it has not been studied in caregivers of cognitively intact people with PD, to our knowledge.”
Kang, C., Sun, S., Yang, Z., Fan, X., Yuan, J., Xu, L., Wei, Y., Tong, H., & Yang, J. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.738579 · Cited by 33 · cited 1× · see citing works
“Initial reports of online MBIs offered during the pandemic have underscored the feasibility of these interventions, although their effectiveness has not yet been fully established (Accoto et al., 2021; Kang et al., 2021; Nourian et al., 2021).”
BackgroundTorales, J., Vilallba-Arias, J., Bogado, J. A., O’Higgins, M., Almirón-Santacruz, J., Ruiz Díaz, N., García, O., Amarilla-Salvioni, D., Castaldelli-Maia, J. M., Ventriglio, A., et al. (2023) · International Journal of Social Psychiatry · doi:10.1177/00207640211070762 · Cited by 31 · cited 1× · see citing works
“The COVID-19 pandemic imposed the sudden conversion of in-person to telehealth visits in healthcare systems throughout the world (Chen et al., 2020; Torales et al., 2022).”
BackgroundTOLOSA, E. S., Ebersbach, G., Ferreira, J. J., Rascol, O., Antonini, A., Foltynie, T., Gibson, R., Magalhães, D., Rocha, J., & Lees, A. J. (2021) · Journal of Parkinson s Disease · doi:10.3233/jpd-212611 · Cited by 23 · cited 2× · see citing works
“Over half (65%) are women and spend an average of 22 h per week supporting their partners with PD (Tolosa et al., 2021).”
BackgroundXia, T. C., Hu, H., Seritan, A. L., & Eisendrath, S. (2019) · Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2019.0137 · Cited by 19 · cited 1× · see citing works
“This was expected since MBIs, as well as some non-MBIs, can enhance mindfulness skills (Xia et al., 2019).”
BackgroundSelf-citationMindfulness-based lifestyle programs for the self-management of Parkinson’s disease in Australia
Vandenberg, B. E., Advocat, J., Hassed, C., Hester, J., Enticott, J., & Russell, G. (2019) · Health Promotion International · doi:10.1093/heapro/day021 · Cited by 17 · cited 2× · see citing works
“An emerging body of evidence highlights the effectiveness of MBIs for people with PD, showing reduced anxiety and depressive symptoms and improvement in activities of daily living, cognitive functioning, motor symptoms, and general well-being, although studies were small and had mixed results (Advocat et al., 2016; Bi…”
BackgroundMartorella, G., Hanley, A. W., Pickett, S. M., & Gélinas, C. (2021) · JMIR Research Protocols · doi:10.2196/30951 · Cited by 16 · cited 1× · see citing works
“A double-blind RCT of a 4-week web-based MBCT intervention to prevent chronic pain after cardiac surgery is in progress (Martorella et al., 2021).”
BackgroundBuchwitz, T. M., Maier, F., Greuel, A., Thieken, F., Steidel, K., Jakobs, V., & Eggers, C. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.763350 · Cited by 15 · cited 1× · see citing works
“Other teams sought to improve awareness of motor symptoms by using mindfulness or a novel body awareness training (BEWARE) that combined physical therapy with acceptance and commitment therapy elements (Buchwitz et al., 2021; Ghielen et al., 2017).”
BackgroundBehavioral symptomatology and psychopharmacology of Lewy body dementia
Tampi, R. R., Young, J. J., & Tampi, D. J. (2019) · Handbook of clinical neurology · doi:10.1016/b978-0-444-64012-3.00005-8 · Cited by 14 · cited 3× · see citing works
“Three participants initially diagnosed with parkinsonism: one female fragile X premutation carrier, one woman with suspected progressive supranuclear palsy (PSP), and one man believed to have early dementia with Lewy bodies (DLB) also completed the intervention.”
BackgroundBono, A. D., Twaite, J. T., Krch, D., McCabe, D. L., Scorpio, K. A., Stafford, R. J., & Borod, J. C. (2021) · Handbook of clinical neurology · doi:10.1016/b978-0-12-822290-4.00015-3 · Cited by 12 · cited 3× · see citing works
“Three participants initially diagnosed with parkinsonism: one female fragile X premutation carrier, one woman with suspected progressive supranuclear palsy (PSP), and one man believed to have early dementia with Lewy bodies (DLB) also completed the intervention.”
BackgroundEdwards, E., & Carroll, C. (2020) · Journal of Parkinson s Disease · doi:10.3233/jpd-202169 · Cited by 3 · cited 1× · see citing works
“This study was conducted during the COVID-19 pandemic, which greatly affected people with PD and their caregivers, increasing stress and exacerbating anxiety and mood difficulties (Brown et al., 2020; van der Heide et al., 2020; Edwards & Carroll, 2020).”
BackgroundSeritan, A., Iosif, A.-M., Wang, S., Dodge, M., & Eisendrath, S. (2021) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2021.01.128 · Cited by 2 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 2
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Cited by
Sorted by citations
Climate Change and Aging: Implications for Psychiatric Care
Mehta, M. M., Johnson, A. E., Ratnakaran, B., Seritan, I., & Seritan, A. L. (2024) · Current Psychiatry Reports · doi:10.1007/s11920-024-01525-0 · Cited by 20 · see citing works
“Older adults, including those with neuro-degenerative diseases such as PD had high adoption rates of online therapeutic interventions during the COVID-19 pandemic [100], and online group CBT for PTSD has demonstrated comparable effectiveness to in-person delivery [101].”
Self-citationLin, H., Tam, K., & Kuan, Y. (2023) · European Journal of Neurology · doi:10.1111/ene.15839 · Cited by 19 · see citing works
Longacre, M. L., Roche, L., Kueppers, G. C., & Buurman, B. (2025) · Healthcare · doi:10.3390/healthcare13010079 · Cited by 12 · see citing works
“Interventions focused on music therapy [36], mindfulness [27,39], mentorship [41], and education [30], with music therapy being found effective in reducing apathy in PwP and mindfulness effective in improving the reported relaxation of care-givers.”
Zhao, Y., Wu, W., Wu, J., Shen, B., Cao, Y., & Xu, Y. (2024) · Quality of Life Research · doi:10.1007/s11136-024-03616-0 · Cited by 9 · see citing works
“…30–36, 38–41, 46, 49–53, 55–61, 63, 65–68, 71, 72, 74], thirty-eight articles are cross-sectional studies [6, 7, 13, 14, 16, 19–21, 23, 25–28, 30–32, 34, 36, 38–41, 46, 49, 51–53, 55, 56, 59–61, 63, 65–68, 74] and eleven are randomized clinical trials [3, 10, 11, 15, 33, 35, 50, 57, 58, 71, 72].”
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La pleine conscience (mindfulness) en neurologie : qu’en attendre ?
Tison, F. (2024) · Pratique Neurologique - FMC · doi:10.1016/j.praneu.2024.10.004 · Cited by 1 · see citing works
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“Previous studies have demonstrated that dyadic mindfulness interventions [89–91] and multidis‑ ciplinary rehabilitation programs [92] improve depression in PwPD and their CP.”
BackgroundAhmadi, N., Sasangohar, F., Jones-wood, S., Moskowitz, J. T., & Phillips, R. (2025) · doi:10.2196/preprints.90531
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“Several studies have affirmed the feasibility and effectiveness of eMBCT [34, 35], with no reported adverse effects.”
- Authors
- Seritan, A. L., Iosif, A.-M., Prakash, P., Wang, S. S., & Eisendrath, S.
- Affiliations
- University of California, San Francisco (US)
- University of California, Davis (US)
- Brown University (US)
- Corresponding author
- Seritan, Andreea L.
- Venue
- Journal of Technology in Behavioral Science
- Published
- 2022-05-02
- Volume
- 7
- Issue
- 3
- Pages
- 381-395
- ISSN
- 2366-5963 (ISSN-L)
- PMC
- PMC9059916
- OpenAlex
- W4225272128
- Cited by
- 16
- References
- 74
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 6 · 2023: 3
- FWCI
- 2.97
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Technology in Behavioral Science (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- Mount Zion Health Fund (20200962)
- University of California, Davis (P50MH106438)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Keywords
- Parkinson's disease, mindfulness-based cognitive therapy, online intervention, caregiver burden, anxiety, depression, non-motor symptoms, feasibility, mindfulness
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