The DOI matches its Crossref record; 470 of the 470 references it cites were found in a registry or an index.
Photodynamic therapy: Innovative approaches for antibacterial and anticancer treatments
Open accessAbstract
Photodynamic therapy is an alternative treatment mainly for cancer but also for bacterial infections. This treatment dates back to 1900 when a German medical school graduate Oscar Raab found a photodynamic effect while doing research for his doctoral dissertation with Professor Hermann von Tappeiner. Unexpectedly, Raab revealed that the toxicity of acridine on paramecium depends on the intensity of light in his laboratory. Photodynamic therapy is therefore based on the administration of a photosensitizer with subsequent light irradiation within the absorption maxima of this substance followed by reactive oxygen species formation and finally cell death. Although this treatment is not a novelty, there is an endeavor for various modifications to the therapy. For example, selectivity and efficiency of the photosensitizer, as well as irradiation with various types of light sources are still being modified to improve final results of the photodynamic therapy. The main aim of this review is to summarize anticancer and antibacterial modifications, namely various compounds, approaches, and techniques, to enhance the effectiveness of photodynamic therapy.
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Cites
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Cited by
Recent advances in photo‐responsive carbon dots for tumor therapy
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Metadata
- Authors
- Kolarikova, M., Hosikova, B., Dilenko, H., Barton‐Tomankova, K., Valkova, L., Bajgar, R., Malina, L., & Kolarova, H.
- Venue
- Medicinal Research Reviews
- Publisher
- Wiley
- Published
- 2023-02-09
- Volume
- 43
- Issue
- 4
- Pages
- 717-774
- ISSN
- 0198-6325 (ISSN-L)
- 1098-1128
- OpenAlex
- W4319656487
- Cited by
- 282
- References
- 470
- FWCI
- 44.80
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Kolarikova, M., Hosikova, B., Dilenko, H., Barton‐Tomankova, K., Valkova, L., Bajgar, R., Malina, L., & Kolarova, H. (2023). Photodynamic therapy: Innovative approaches for antibacterial and anticancer treatments. Medicinal Research Reviews. https://doi.org/10.1002/med.21935
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
