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Cited by 235

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Sarcoplasmic reticulum: The dynamic calcium governor of muscle

Rossi, Ann E., Dirksen, Robert T.·2006·Muscle & Nerve

Abstract

The sarcoplasmic reticulum (SR) provides feedback control required to balance the processes of calcium storage, release, and reuptake in skeletal muscle. This balance is achieved through the concerted action of three major classes of SR calcium‐regulatory proteins: (1) luminal calcium‐binding proteins (calsequestrin, histidine‐rich calcium‐binding protein, junctate, and sarcalumenin) for calcium storage; (2) SR calcium release channels (type 1 ryanodine receptor or RyR1 and IP 3 receptors) for calcium release; and (3) sarco(endo)plasmic reticulum Ca 2+‐ATPase (SERCA) pumps for calcium reuptake. Proper calcium storage, release, and reuptake are essential for normal skeletal muscle function. We review SR structure and function during normal skeletal muscle activity, the proteins that orchestrate calcium storage, release, and reuptake, and how phenotypically distinct muscle diseases (e.g., malignant hyperthermia, central core disease, and Brody disease) can result from subtle alterations in the activity of several key components of the SR calcium‐regulatory machinery. Muscle Nerve, 2006

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Metadata

Authors
Rossi, A. E., & Dirksen, R. T.
Venue
Muscle & Nerve
Publisher
Wiley
Published
2006-02-13
Volume
33
Issue
6
Pages
715-731
ISSN
  • 0148-639X (ISSN-L)
  • 1097-4598
OpenAlex
W2067146747
Cited by
235
References
2
FWCI
6.14
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Sarcoplasmic reticulum: The dynamic calcium governor of muscle. https://app.cochat.ai/papers/10.1002/mus.20512
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Rossi, A. E., & Dirksen, R. T. (2006). Sarcoplasmic reticulum: The dynamic calcium governor of muscle. Muscle & Nerve. https://doi.org/10.1002/mus.20512

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