Imaging guidelines for children with Ewing sarcoma and osteosarcoma: A report from the Children's Oncology Group Bone Tumor Committee
Abstract
The Children's Oncology Group (COG) is a multi‐institutional cooperative group dedicated to childhood cancer research that has helped to increase the survival of children with cancer through clinical trials. These clinical trials include a standardized regimen of imaging examinations performed prior to, during, and following therapy. This article presents imaging guidelines developed by a multidisciplinary group from the COG Bone Tumor Committee. These guidelines provide both required and recommended studies. Recommended examinations may become required in the future. These guidelines should be considered a work in progress that will evolve with advances in imaging and childhood cancer research. Pediatr Blood Cancer 2008;51:163–170. © 2008 Wiley‐Liss, Inc.
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The 2008 Children's Oncology Group guidelines, still widely accepted, advocate PET imaging with whole-body CT or MRI, and isotope bone scans if those modalities are unavailable.
“In 2008, guidelines from the Children's Oncology Group were published 107 , and are still widely accepted, advocating PET imaging with accompanying whole-body CT or whole-body MRI, with isotope bone scans if these modalities are not available.”
From Osteosarcoma (2022) · cites this paper as [107]
The recommended staging work-up reveals lung metastases in 15-20% of patients and occasionally identifies tumours in other bones or, rarely, other sites.
“This work-up recommendation reveals lung metastases in 15-20% of patients, and occasionally identifies tumours within other bones or, very rarely, lesions at other sites.”
From Osteosarcoma (2022) · cites this paper as [107]
Skeletal imaging with PET or technetium bone scans is important to identify covert bony disease.
“Skeletal imaging with PET or technetium bone scans is important to identify covert bony disease 107 .”
From Osteosarcoma (2022) · cites this paper as [107]
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- Authors
- Meyer, J. S., Nadel, H. R., Marina, N., Womer, R. B., Brown, K. L. B., Eary, J. F., Gorlick, R., Grier, H. E., Randall, R. L., Lawlor, E. R., Lessnick, S. L., Schomberg, P. J., & Kailo, M. D.
- Affiliations
- Children's Hospital of Philadelphia (US)
- University of British Columbia (CA)
- Lucile Packard Children's Hospital (US)
- University of Washington (US)
- Albert Einstein College of Medicine (US)
- Harvard University (US)
- University of Utah (US)
- University of Southern California (US)
- Mayo Clinic (US)
- Corresponding author
- Meyer, James S.
- ORCID
- Venue
- Pediatric Blood & Cancer
- Publisher
- Wiley
- Published
- 2008-05-02
- Volume
- 51
- Issue
- 2
- Pages
- 163-170
- ISSN
- 1545-5009 (ISSN-L)
- 1545-5017
- OpenAlex
- W2055819634
- Cited by
- 180
- References
- 40
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 12 · 2023: 12 · 2022: 9 · 2021: 11 · 2020: 10 · 2019: 4 · 2018: 7 · 2017: 11 · 2016: 14 · 2015: 10 · 2014: 13 · 2013: 10 · 2012: 8
- FWCI
- 11.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pediatric Blood & Cancer (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Cancer Institute (U10CA098543)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Sarcoma Diagnosis and Treatment
- Health Sciences › Medicine › Rheumatology › Bone Tumor Diagnosis and Treatments
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Acute Lymphoblastic Leukemia research
- Keywords
- Ewing sarcoma, osteosarcoma, pediatric bone tumors, imaging guidelines, diagnostic imaging, treatment response assessment, Children's Oncology Group, bone tumor imaging
- MeSH terms
- Bone Neoplasms, Child, Humans, Magnetic Resonance Imaging, Sarcoma, Ewing, Tomography, X-Ray Computed, Fluorodeoxyglucose F18, Positron-Emission Tomography
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