Lost at Sea in Search of a Diagnosis: A Case of Unexplained Bleeding
Open accessAbstract
Scurvy results from a dietary deficiency of vitamin C (ascorbic acid) and is rarely thought of in modern day medicine. It now almost always occurs in pediatric patients with behavioral diagnoses, nutritionally restricted diets, and food allergies. Symptoms of scurvy include ecchymoses, bleeding gums, and arthralgias. Here, we present a 17‐year‐old male with autism spectrum disorder and a diet severely deficient in ascorbic acid due to textural aversion and food preferences. He presented with recurrent arthritis, hemarthrosis, bruising, and anemia. His vitamin C level was low, and his symptoms improved promptly after treatment with ascorbic acid.
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The literature on children and young people with autism with severe food restriction reports health issues stemming from the lack or absence of certain micronutrients, including jaundice, anaemia, scurvy, rickets, gingivitis, and hypogonadism.
“The literature on children and young people with autism with severe food restriction reports a number of health issues stemming from the lack or absence of certain micronutrients, including jaundice, anaemia, scurvy, rickets, gingivitis, and hypogonadism.40,59,61,64,65,[68][69][70]”
From Avoidant/Restrictive Food Intake Disorder and Severe Food Selectivity in Children and Young People with Autism: A Scoping Review (2022) · cites this paper as [61]
There is reliable evidence to suggest that ARFID and severe food restriction in children and young people with autism is associated with a greater risk of poor health outcomes.
“There is reliable evidence to suggest that ARFID and severe food restriction in children and young people with autism is associated with a greater risk of poor health outcomes.59,[61][62][63][64][65]”
From Avoidant/Restrictive Food Intake Disorder and Severe Food Selectivity in Children and Young People with Autism: A Scoping Review (2022) · cites this paper as [61]
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- Authors
- Amos, L. E., Carpenter, S. L., & Hoeltzel, M. F.
- Affiliations
- Children's Mercy Hospital (US)
- University of Michigan (US)
- Corresponding author
- Amos, Lauren E.
- Venue
- Pediatric Blood & Cancer
- Publisher
- Wiley
- Published
- 2016-04-08
- Volume
- 63
- Issue
- 7
- Pages
- 1305-1306
- ISSN
- 1545-5009 (ISSN-L)
- 1545-5017
- OpenAlex
- W2337749057
- Cited by
- 7
- References
- 5
- Citations by year
- 2023: 2 · 2022: 1 · 2020: 3 · 2016: 1
- FWCI
- 0.35
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Locations
- Pediatric Blood & Cancer (publishedVersion)
- PubMed (publishedVersion)
- Deep Blue (University of Michigan) (submittedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Vitamin C and Antioxidants Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Keywords
- scurvy, vitamin C, autism spectrum disorder, dietary restriction, food preferences, hemarthrosis, anemia, ecchymoses, arthritis, bleeding disorders
- MeSH terms
- Autism Spectrum Disorder, Adolescent, Ascorbic Acid, Hemorrhage, Humans, Male, Scurvy
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