Sexual functioning in young adult survivors of childhood cancer
Open accessAbstract
BACKGROUND: Studies of sexuality or sexual behavior in childhood cancer survivors tend to examine relationships or achievement of developmental milestones but not physiological response to cancer or treatment. The purpose of this study is to (1) identify prevalence and risk factors for sexual dysfunction in childhood cancer survivors, and (2) examine the extent to which sexual dysfunction may be associated with health-related quality of life (HRQOL) and psychosocial outcomes. METHODS: Five hundred ninety-nine survivors age 18-39 years completed standardized measures of sexual functioning, HRQOL, psychological distress and life satisfaction. Descriptive statistics assessed prevalence of sexual symptoms. Bivariate analyses identified correlates of sexual symptoms and examined associations between symptoms and HRQOL/psychosocial outcomes. RESULTS: Most survivors appear to be doing well, although 52% of female survivors and 32% of male survivors reported at least 'a little of a problem' in one or more areas of sexual functioning. Mean symptom score for females was more than twice that of males. Sexual symptoms were associated with reporting health problems. Significant associations between sexual functioning and HRQOL outcomes were observed, with gender differences in strengths of association suggesting that males find sexual symptoms more distressing than do females. CONCLUSIONS: While most survivors appear to be doing well in this important life domain, some young adult survivors report sexual concerns. While female survivors may report more sexual symptoms than male survivors, males may experience more distress associated with sexual difficulties. Better-specified measures of sexual function, behavior and outcomes are needed for this young adult population.
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Female survivors report greater impairment on sexual functioning than male survivors.
“Female survivors report greater impairment on sexual functioning than male survivors (Hovén et al., 2021; Lehmann et al., 2022; Zebrack et al., 2010).”
From Efficacy of a web-based psychoeducational intervention, Fex-can sex, for young adult childhood cancer survivors with sexual dysfunction: A randomized controlled trial (2024) · cites this paper as Zebrack et al., 2010
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“and a greater risk of sexual dysfunction (Ganz et al. 1998; van Dijk et al. 2008; Zebrack et al. 2010).”
BackgroundInfluentialManagement of sexual problems in cancer patients and survivors
Varela, V. S., Zhou, E. S., & Bober, S. L. (2013) · Current Problems in Cancer · doi:10.1016/j.currproblcancer.2013.10.009 · Cited by 50 · see citing works
Female Sexual Health Training for Oncology Providers: New Applications
Wang, L. Y., Pierdomenico, A. M., Lefkowitz, A., & Brandt, R. (2015) · Sexual Medicine · doi:10.1002/sm2.66 · Cited by 45 · see citing works
Sexual function in adolescent and young adult cancer survivors—a population-based study
Olsson, M., Steineck, G., Enskär, K., Wilderäng, U., & Jarfelt, M. (2018) · Journal of Cancer Survivorship · doi:10.1007/s11764-018-0684-x · Cited by 44 · see citing works
“Knowledge on treatment-related sexual dysfunction in adults needs to be complemented on AYA sexual function after cancer treatment [8].”
BackgroundSexuality After Cancer: A Model for Male Survivors
Katz, A., & Dizon, D. S. (2016) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2015.11.006 · Cited by 43 · see citing works
“This was most notably shown in a study of adolescent and young adult cancer survivors (mean 1⁄4 16 years since the index diagnosis of cancer), 62% of whom had a hematologic malignancy.(10)”
ResultGraugaard, C. L., Sperling, C. D., Hølge‐Hazelton, B., Boisen, K. A., & Petersen, G. S. (2018) · Psycho-Oncology · doi:10.1002/pon.4700 · Cited by 42 · see citing works
Sexual function in male long‐term survivors of childhood acute lymphoblastic leukemia
Haavisto, A., HENRIKSSON, M. M., Heikkinen, R., Puukko‐Viertomies, L., & Jahnukainen, K. (2016) · Cancer · doi:10.1002/cncr.29989 · Cited by 41 · see citing works
“childhood cancer survivors.(7,8) This decline in sexual health occurs at an earlier age than in the general population and is best understood as a late effect of cancer treatment, as discussed by Bober et al.”
BackgroundResultInfluentialCounseling in Pediatric Populations at Risk for Infertility and/or Sexual Function Concerns
Nahata, L., Quinn, G. P., Tishelman, A. C., ENDOCRINOLOGY, S. O., Lynch, J. L., Brodsky, J. L., Casella, S. J., DiMeglio, L. A., López, X., Wintergerst, K. A., et al. (2018) · PEDIATRICS · doi:10.1542/peds.2018-1435 · Cited by 41 · see citing works
Facing the unknown: uncertain fertility in young adult survivors of childhood cancer
Newton, K., Howard, A. F., Thorne, S. E., Kelly, M. T., & Goddard, K. (2020) · Journal of Cancer Survivorship · doi:10.1007/s11764-020-00910-x · Cited by 41 · see citing works
Lehmann, V., Hagedoorn, M., Gerhardt, C. A., Fults, M. Z., Olshefski, R. S., Sanderman, R., & Tuinman, M. A. (2015) · Psycho-Oncology · doi:10.1002/pon.3841 · Cited by 39 · see citing works
Hidalgo, E. T., Orillac, C. M., Kvint, S., McQuinn, M. W., Dastagirzada, Y. M., Phillips, S., & Wisoff, J. H. (2019) · Child s Nervous System · doi:10.1007/s00381-019-04161-9 · Cited by 38 · see citing works
Sexual dysfunction in young adult survivors of childhood cancer - a population-based study
Hovén, E., Fagerkvist, K., Jahnukainen, K., Ljungman, L., Lähteenmäki, P. M., Axelsson, O., Lampic, C., & Wettergren, L. (2021) · European Journal of Cancer · doi:10.1016/j.ejca.2021.06.014 · Cited by 37 · see citing works
“Sexual dysfunction has been reported for 20 e 52% of female and 20 e 32% of male survivors of childhood cancer [6,13,15].”
BackgroundInfluentialJervaeus, A., Nilsson, J., Eriksson, L. E., Lampic, C., Widmark, C., & Wettergren, L. (2015) · European Journal of Oncology Nursing · doi:10.1016/j.ejon.2015.07.009 · Cited by 36 · see citing works
“Bober et al. (2013) and Zebrack et al. (2010) have reported that the most common sexual dysfunctions among survivors of childhood cancer are lack of interest, dif fi culties becoming aroused and enjoying sex, and erectile dysfunction.”
Sopfe, J., Gupta, A. A., Appiah, L. A., Chow, E. J., & Peterson, P. N. (2020) · Journal of Adolescent and Young Adult Oncology · doi:10.1089/jayao.2020.0025 · Cited by 35 · see citing works
“20,21,28,29 Notably, those studies that demonstrated being partnered as a risk factor for SD specifically found this to be true in females.”
InfluentialBelpame, N., Kars, M. C., Deslypere, E., Rober, P., Hecke, A. V., & Verhaeghe, S. T. L. (2019) · Journal of Pediatric Nursing · doi:10.1016/j.pedn.2019.07.015 · Cited by 34 · see citing works
Lindau, S. T., Abramsohn, E., Baron, S. R., Florendo, J., Haefner, H. K., Jhingran, A., Kennedy, V. A., Krane, M. K., Kushner, D. M., McComb, J., et al. (2016) · CA A Cancer Journal for Clinicians · doi:10.3322/caac.21337 · Cited by 33 · see citing works
Psychosexual Care of Adolescent and Young Adult (AYA) Cancer Survivors
Reinman, L., Coons, H. L., Sopfe, J., & Casey, R. L. (2021) · Children · doi:10.3390/children8111058 · Cited by 31 · see citing works
“This may be due to the changes in physical function that female AYA cancer survivors have to manage, and because of increased levels of fatigue [17,30].”
Background“A Tribe Apart”: Sexuality and Cancer in Adolescence
Moules, N. J., Estefan, A., Laing, C. M., Schulte, F., Guilcher, G. M. T., Field, J., & Strother, D. R. (2017) · Journal of Pediatric Oncology Nursing · doi:10.1177/1043454217697669 · Cited by 31 · see citing works
“Issues of adolescence are sometimes addressed retrospectively after long periods of time, for example, inquiring into marital relationships in adulthood among people who had cancer in adolescence (Zebrack & Chesler, 2001), or examining variables among adolescents who previously had cancer in childhood (Zebrack et al.,…”
BackgroundFertility and sexual dysfunction in young male cancer survivors
Yumura, Y., Takeshima, T., Komeya, M., Kuroda, S., Saito, T., & Karibe, J. (2022) · Reproductive Medicine and Biology · doi:10.1002/rmb2.12481 · Cited by 30 · see citing works
Rehabilitation of patients with glioma
Vargo, M. M., Henriksson, R., & Salander, P. (2016) · Handbook of clinical neurology · doi:10.1016/b978-0-12-802997-8.00017-7 · Cited by 30 · see citing works
Heyne, S., Esser, P., Geue, K., Friedrich, M., & Mehnert, A. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.679870 · Cited by 30 · see citing works
“Detrimental effects on sexuality through cancer and its treatment are common (Zebrack et al., 2010; Bober et al., 2013).”
BackgroundHong, H. C., Min, A., & Kim, Y. M. (2022) · Journal of Clinical Nursing · doi:10.1111/jocn.16201 · Cited by 29 · see citing works
Quality of life in female cancer survivors: is it related to ovarian reserve?
Kondapalli, L. A., Dillon, K., Sammel, M. D., Ray, A., Prewitt, M., Ginsberg, J. P., & Gracia, C. R. (2013) · Quality of Life Research · doi:10.1007/s11136-013-0473-y · Cited by 27 · see citing works
“This finding is consistent with other reports of psychosexual problems in childhood cancer survivors [21, 22].”
ResultReproductive Care of Childhood and Adolescent Cancer Survivors: A 12-Year Evaluation
Anazodo, A. C., Choi, S., Signorelli, C., Ellis, S. J., Johnston, K. A., Wakefield, C. E., Deans, R., Neville, K. A., & Cohn, R. J. (2020) · Journal of Adolescent and Young Adult Oncology · doi:10.1089/jayao.2020.0157 · Cited by 26 · see citing works
Bjornard, K. L., Howell, C. R., Klosky, J. L., Chemaitilly, W., Srivastava, D. K., Brinkman, T. M., Green, D. M., Willard, V. W., Jacola, L. M., Krasin, M. J., et al. (2020) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2020.06.005 · Cited by 25 · see citing works
Ellingson, L. L. (2017) · Management Communication Quarterly · doi:10.1177/0893318917689894 · Cited by 23 · see citing works
Gonadal and Sexual Dysfunction in Childhood Cancer Survivors
Yoon, J. Y., Park, H. J., Ju, H. Y., Yoon, J. H., Chung, J. S., Hwang, S., Lee, D. O., Shim, H. Y., & Park, B.-K. (2017) · Cancer Research and Treatment · doi:10.4143/crt.2016.197 · Cited by 23 · see citing works
Investigating sexuality in adolescents with cancer: patients talk of their experiences
Veneroni, L., Bagliacca, E. P., Sironi, G., Silva, M., Casanova, M., Bergamaschi, L., Terenziani, M., Trombatore, J., Clerici, C. A., Prunas, A., et al. (2020) · Pediatric Hematology and Oncology · doi:10.1080/08880018.2020.1712502 · Cited by 22 · see citing works
“”(3) Social isolation may ultimately limit the chances of sexual encounters.(6,7,9) We found that a large proportion of our patients had difficulty in their emotionally important relationships with people as a consequence of the disease and its treatments.”
BackgroundLehmann, V., Tuinman, M. A., Keim, M. C., Winning, A. M., Olshefski, R. S., Bajwa, R. P. S., Hagedoorn, M., & Gerhardt, C. A. (2017) · Cancer · doi:10.1002/cncr.30513 · Cited by 21 · see citing works
Frederick, N. N., Bingen, K. M., Bober, S. L., Cherven, B. O., Xu, X., Quinn, G. P., Ji, L., & Freyer, D. R. (2021) · Cancer Medicine · doi:10.1002/cam4.4077 · Cited by 20 · see citing works
Fish, J. D. (2011) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2010.11.001 · Cited by 18 · see citing works
Frederick, N. N., Fine, E., Michaud, A. L., Recklitis, C. J., & Bober, S. L. (2020) · Pediatric Blood & Cancer · doi:10.1002/pbc.28245 · Cited by 18 · see citing works
Psychosexual development and sexual functioning in young adult survivors of childhood cancer
Lehmann, V., Gerhardt, C. A., Baust, K., Kaatsch, P., Hagedoorn, M., & Tuinman, M. A. (2022) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2022.07.014 · Cited by 17 · see citing works
Sopfe, J., Marsh, R., Frederick, N. N., Klosky, J. L., Chow, E. J., Holliman, B. D., & Peterson, P. N. (2021) · Pediatric Blood & Cancer · doi:10.1002/pbc.29229 · Cited by 16 · see citing works
Applicability and evaluation of a psychosocial intervention program for childhood cancer patients
van Dijk‐Lokkart, E. M., Braam, K. I., Kaspers, G. J. L., Broeder, E. V. D., Takken, T., Grootenhuis, M. A., Streng, I. C., Bierings, M., Merks, J. H. M., van den Heuvel‐Eibrink, M. M., et al. (2015) · Supportive Care in Cancer · doi:10.1007/s00520-014-2576-6 · Cited by 16 · see citing works
“Although in recent decades considerable attention in childhood oncology has focused on problems with relationships and sexuality [18–24], this was found to be the least important topic by patients, parents, and psychologists.”
BackgroundHu, Y., Ma, Z., Zhang, H., Gao, T., Gao, J., Kong, Y., Qin, Z., & Mei, S. (2018) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2018.08.015 · Cited by 16 · see citing works
Sopfe, J., Marsh, R., Ziniel, S. I., Klosky, J. L., Chow, E. J., Dorsey Holliman, B., & Peterson, P. N. (2021) · Journal of Adolescent and Young Adult Oncology · doi:10.1089/jayao.2020.0166 · Cited by 15 · see citing works
Wayant, C., Manquen, J., Wendelbo, H., Kerr, N., Crow, M., Goodell, J., Tricco, A. C., Mack, J. W., Hellman, C. M., & Vassar, M. B. (2021) · Journal of Adolescent and Young Adult Oncology · doi:10.1089/jayao.2020.0184 · Cited by 14 · see citing works
“Sexual dysfunction and disfigurement from treatment contributed to lower life satisfaction.(124,158) 252 WAYANT ET AL.”
BackgroundMoules, N. J., Laing, C. M., Estefan, A., Schulte, F., & Guilcher, G. M. T. (2018) · Journal of Family Nursing · doi:10.1177/1074840718786985 · Cited by 12 · see citing works
Mitchell, L. E., Lewin, J. H., Dirks, J., Wang, K., Tam, S., Katz, A., McCann, B., Lo, K. C., Laurence, V., Rousset‐Jablonski, C., et al. (2018) · Journal of Adolescent and Young Adult Oncology · doi:10.1089/jayao.2017.0067 · Cited by 13 · see citing works
“Survivors of pediatric cancer have reported SD in 10%–40% of AYA, higher than population data.(32,38) For those diagnosed with cancer in the AYA years, the prevalence has been estimated between 20% and 50% although much of these analyses have been limited to patients with testicular cancer (TC) and thus represents an…”
Sexuality and cancer: The experience of adolescents and young adults
Soanes, L., & White, I. D. (2018) · Pediatric Blood & Cancer · doi:10.1002/pbc.27396 · Cited by 13 · see citing works
Urological Survivorship Issues Among Adolescent Boys and Young Men Who Are Cancer Survivors
Sukhu, T. A., Ross, S. S., & Coward, R. M. (2018) · Sexual Medicine Reviews · doi:10.1016/j.sxmr.2017.12.007 · Cited by 12 · see citing works
Dating and Disclosure for Cancer Survivors
Hamilton, R., & Zebrack, B. (2011) · Humana Press eBooks · doi:10.1007/978-1-60761-916-1_50 · Cited by 12 · see citing works
Acquati, C., Wittmann, D. A., Roth, M. E., Rosen, A., Carr, L. C., Gresham, Z., & Ionescu, E. (2023) · JMIR Research Protocols · doi:10.2196/41831 · Cited by 12 · see citing works
“Differences exist by sex, with females reporting higher dysfunction scores [30-32].”
Biopsychosocial Evaluation of Sexual Dysfunctions
Pahwa, P., & Foley, S. (2017) · Springer eBooks · doi:10.1007/978-3-319-52539-6_6 · Cited by 11 · see citing works
Study protocol for the Fex-Can Childhood project
Ljungman, L., Anandavadivelan, P., Jahnukainen, K., Lampic, C., & Wettergren, L. (2020) · Medicine · doi:10.1097/md.0000000000019919 · Cited by 11 · see citing works
Gerstl, B., Signorelli, C., Wakefield, C. E., Deans, R., Vaishnav, T., Johnston, K. A., Neville, K. A., Cohn, R. J., & Anazodo, A. C. (2023) · Journal of Cancer Survivorship · doi:10.1007/s11764-023-01349-6 · Cited by 10 · see citing works
“…or absent pubertal development) [8, 42, 43]; menstrual dysfunction [8, 44]; endocrine complications [8, 45–47]; sexual dysfunction disorders [1, 8, 48]; infertility [8, 49]; and obstetric and perinatal complications [8, 50–52] limits collaboration between healthcare professionals outside of a…”
Alsuliman, T., Alasadi, L., Poloméni, A., Capes, A., Perić, Z., Linke, A., Schoemans, H. M., Malard, F., Chalandon, Y., & Mohty, M. (2024) · The Lancet Haematology · doi:10.1016/s2352-3026(24)00209-6 · Cited by 10 · see citing works
Pérez, A. B., & Verdet, H. M. (2015) · Psicooncología · doi:10.5209/rev_psic.2015.v12.n1.48909 · Cited by 10 · see citing works
“Cuestiones como la preservación de la fertilidad pueden tener poco peso o interés en un joven adolescente(58), pero puede ser de interés primordial para la misma persona en la vida adulta(46).”
BackgroundSexual Dysfunction Among Adolescent and Young Adult Men Diagnosed with Cancer
Rainer, Q. C., Dubin, J. M., Balaji, N. C., Troesch, V., Terry, W. W., Monga, V., Clifford, L., Shoag, J. M., Greer, A. B., Nackeeran, S., et al. (2022) · Journal of Adolescent and Young Adult Oncology · doi:10.1089/jayao.2021.0211 · Cited by 9 · see citing works
“11,12 However, recent studies have shown female pediatric cancer survivors have higher odds of reporting sexual dysfunction after treatment.”
Patient-Reported Sexual Function Among Young Adult Cancer Survivors
Fitz, V. W., Anderson, C., Manuck, T. A., Mersereau, J. E., Bensen, J. T., Park, J., & Nichols, H. B. (2022) · Journal of Adolescent and Young Adult Oncology · doi:10.1089/jayao.2022.0079 · Cited by 9 · see citing works
“6,10,13 14–16 However, prior studies have used a variety of assessment tools, often with only a single item to assess sexual function.”
Bergerot, C. D., Wang, A. W.-T., Dégi, L. C., Bahçivan, O., & Kim, Y. (2023) · Cancer Investigation · doi:10.1080/07357907.2023.2167210 · Cited by 9 · see citing works
Fagerkvist, K., Jahnukainen, K., Ljungman, L., Lampic, C., & Wettergren, L. (2024) · Internet Interventions · doi:10.1016/j.invent.2024.100739 · Cited by 8 · see citing works
“(Bober et al., 2013; Hov ´ en et al., 2021; Zebrack et al., 2010), vulvar discomfort (19 %), and dissatisfaction with one's sex life (18 – 20”
BackgroundSexual health in adult survivors of childhood cancer: A Project REACH study
Chevalier, L., McCormick, K., Cooney, T. M., Recklitis, C. J., & Bober, S. L. (2024) · Cancer · doi:10.1002/cncr.35363 · Cited by 8 · see citing works
“These findings are consistent with existing CCS research, 3,5,6 including our previous study with the sexual health subscale on a health ‐ related quality ‐ of ‐ life survey.”
InfluentialMale and Female Sexual Dysfunction in Pediatric Cancer Survivors
Greenberg, D. R., Khandwala, Y. S., Bhambhvani, H. P., Simon, P. J., & Eisenberg, M. L. (2020) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2020.05.014 · Cited by 8 · see citing works
Yang, F., Ho, K. Y., Yorke, J., Lam, K. K. W., Liu, Q., Guo, L., Fai, N. C., Liu, P. Y. A., Yuen, J. W. M., Belay, G. M., et al. (2024) · EClinicalMedicine · doi:10.1016/j.eclinm.2024.102695 · Cited by 7 · see citing works
“…most studies have indicated a statistically signi fi cantly higher prevalence of sexual dysfunction among CCSs than in the general population 7,37 and a higher prevalence in females than in males in several studies, 7,29,37 it is not possible to pool data for meta-analysis due to…”
BackgroundInfluentialPrimary care for young adult cancer survivors: an international perspective
Hølge‐Hazelton, B., Blake-Gumbs, L., Miedema, B., & van Rijswijk, E. (2010) · Supportive Care in Cancer · doi:10.1007/s00520-010-0954-2 · Cited by 7 · see citing works
“Major medical issues may be secondary malignancies, cardiotoxicity, reproductive difficulties, lymphedema, reduced lung function, cognitive impairment, fatigue, endocrine dysfunction, obesity and metabolic syndrome, thyroid dysfunction, and osteoporosis [17, 18].”
BackgroundFilling the gaps in knowledge and treatments for sexual health in young adult male cancer survivors
Syrjala, K. L. (2016) · Cancer · doi:10.1002/cncr.29988 · Cited by 7 · see citing works
Formations en onco-sexologie : existant et perspectives
Huyghe, É., Almont, T., Burte, C., Marx, E., Habold, D., & Bondil, P. (2016) · Psycho-Oncologie · doi:10.1007/s11839-016-0568-4 · Cited by 7 · see citing works
Crist, N., Egert, M., & Bernie, H. L. (2023) · Sexual Medicine Reviews · doi:10.1093/sxmrev/qeac013 · Cited by 7 · see citing works
Holme, I. K., Hollund, H. A., Vandraas, K. F., Kiserud, C. E., Reinertsen, K. V., Loge, J. H., & Lie, H. C. (2023) · Journal of Adolescent and Young Adult Oncology · doi:10.1089/jayao.2023.0031 · Cited by 7 · see citing works
Fertility Preservation in Girls and Women: State of Art and Future Possibilities
Marin, L., Ambrosini, G., Esposito, F., Capobianco, G., Laganà, A. S., Vio, C., Nuzzi, L., Rossato, M., & Andrisani, A. (2022) · Clinical and Experimental Obstetrics & Gynecology · doi:10.31083/j.ceog4909206 · Cited by 7 · see citing works
“Patients who do not achieve a physiological puberty induction appear to be exposed to a significant risk of psychosexual disturbances that can severely impact their psychological and physical maturation processes [69,70].”
BackgroundHormonal Changes and Sexual Dysfunction
Zhou, E. S., Frederick, N. N., & Bober, S. L. (2017) · Medical Clinics of North America · doi:10.1016/j.mcna.2017.06.008 · Cited by 7 · see citing works
“In contrast, studies in childhood cancer survivors have shown that in addition to disruptions in endocrine function among other physical late effects, psychosocial factors, such as anxiety, fear of partner rejection, fear of being pitied, and poor self-esteem, also play a significant role in the development of sexual…”
ResultPriboi, C., van Gorp, M., Maurice‐Stam, H., Michel, G., Kremer, L. C. M., Tissing, W. J. E., Loonen, J. J., van der Pal, H. J. H., de Vries, A. C. H., van den Heuvel‐Eibrink, M. M., et al. (2023) · Psycho-Oncology · doi:10.1002/pon.6181 · Cited by 6 · see citing works
Chen, Y., Huang, K., Scoglio, A. A. J., Borgogna, N. C., Potenza, M. N., Blycker, G. R., & Kraus, S. W. (2023) · Journal of Trauma & Dissociation · doi:10.1080/15299732.2023.2231915 · Cited by 8 · see citing works
“The scale has been widely used to assess sexual dysfunction in various populations (e.g., Zebrack et al., 2010).”
MethodNg, C., Hong, C. Y., Lau, B. S., Teoh, J. Y., Yee, S. C. H., Leung, A. W. K., & Yuen, J. W. M. (2019) · Hong Kong Medical Journal · doi:10.12809/hkmj197913 · Cited by 5 · see citing works
Psychosexual functioning in cancer survivorship: What the pediatric oncologist needs to know
Frederick, N. N., Lehmann, V., Ahler, A., Carpenter, K. M., Cherven, B. O., Klosky, J. L., Nahata, L., & Quinn, G. P. (2021) · Pediatric Blood & Cancer · doi:10.1002/pbc.28437 · Cited by 5 · see citing works
Quinn, G. P., Murphy, D., Fortier, M. A., Sehovic, I., Eddleton, K. Z., & Huang, I. (2014) · Journal of Adolescent and Young Adult Oncology · doi:10.1089/jayao.2013.0020 · Cited by 4 · see citing works
“5 This may result in stress and decreased satisfaction in romantic relationships, 22 and may impact the frequency and level of interaction within intimate relationships, which contributes to low marriage rates and high relationship distress.”
A crosscut survey on reproductive health in Lithuanian childhood cancer survivors
Stukaitė-Ruibienė, E., Jurkonis, M., Adomaitis, R., Bumbulienė, Ž., Gudlevičienė, Ž., Verkauskas, G., Žagminas, K., Vaiciuniene, R., & Rascon, J. (2021) · Ginekologia Polska · doi:10.5603/gp.a2021.0027 · Cited by 4 · see citing works
“Sexual dysfunction was reported to be one of the most important side effects of pediatric cancer treatment [3].”
BackgroundSexual Function After Colorectal Surgery in Women
Keller, D. S., & Ky-Miyasaka, J. A. (2021) · Springer eBooks · doi:10.1007/978-3-030-66049-9_63 · Cited by 4 · see citing works
Psychosexual functioning in cancer survivorship: What the pediatric oncologist needs to know
Frederick, N. N., Lehmann, V., Ahler, A., Carpenter, K. M., Cherven, B. O., Klosky, J. L., Nahata, L., & Quinn, G. P. (2023) · Pediatric Blood & Cancer · doi:10.1002/pbc.30611 · Cited by 4 · see citing works
Alsuliman, T., Rojas, R. M. M., Basha, A. A., Musiu, P., Magro, L., Testi, A. M., & Mohty, M. (2024) · The Lancet Haematology · doi:10.1016/s2352-3026(24)00244-8 · Cited by 4 · see citing works
Les soins de support pour améliorer l’accompagnement personnalisé des patients
Lervat, C., Vanlemmens, L., Bondil, P., Jacquot, J., Scotté, F., & Gofti‐Laroche, L. (2020) · Bulletin du Cancer · doi:10.1016/j.bulcan.2020.08.008 · Cited by 4 · see citing works
Kieffer, J., Gross, M. J., Schmitt, C., Bordigoni, P., & Sibertin-Blanc, D. (2012) · Psycho-Oncologie · doi:10.1007/s11839-012-0387-x · Cited by 4 · see citing works
Rague, J. T., Varda, B. K., Wagner, A. A., & Lee, R. S. (2018) · Urology · doi:10.1016/j.urology.2018.10.030 · Cited by 4 · see citing works
“Cancer diagnosis and treatment in the adolescent population have been linked to mood and psychosexual development with decreased sexual satisfaction, interest, and orgasmic difficulty reported in up to 10% childhood cancer survivors.(21,22) In our patients, EF did not return until the treatment course was complete and…”
BackgroundSurvivorship in Childhood Cancer
Krivoy, E., Jenney, M. E. M., Mahajan, A., & Nahum, M. P. (2012) · doi:10.1002/9781119941033.ch16 · Cited by 4 · see citing works
Flynn, K. E., Jeffery, D. D., Andersen, B. L., Siston, A. K., Jhingran, A., Baron, S. R., Reese, J. B., Coady, D. J., Carter, J., & Barbera, L. C. (2015) · Journal of Clinical Oncology · doi:10.1200/jco.2015.33.15_suppl.e20592 · Cited by 4 · see citing works
- Authors
- Zebrack, B. J., Foley, S., Wittmann, D., & Leonard, M.
- Affiliations
- University of Michigan (US)
- Michigan Medicine (US)
- U-M Rogel Cancer Center (US)
- Corresponding author
- Zebrack, Brad J.
- Venue
- Psycho-Oncology
- Publisher
- Wiley
- Published
- 2010-07-20
- Volume
- 19
- Issue
- 8
- Pages
- 814-822
- ISSN
- 1057-9249 (ISSN-L)
- 1099-1611
- PMC
- PMC2888926
- OpenAlex
- W2137813841
- Cited by
- 144
- References
- 52
- Citations by year
- 2026: 5 · 2025: 4 · 2024: 11 · 2023: 14 · 2022: 11 · 2021: 9 · 2020: 12 · 2019: 7 · 2018: 11 · 2017: 12 · 2016: 13 · 2015: 8 · 2014: 6 · 2013: 9 · 2012: 4
- FWCI
- 3.22
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Psycho-Oncology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Deep Blue (University of Michigan) (submittedVersion)
- Funders
- U.S. Department of Health and Human Services
- National Institutes of Health
- National Cancer Institute (K07CA100380)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Childhood Cancer Survivors' Quality of Life
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Keywords
- childhood cancer survivors, sexual dysfunction, sexual function, young adults, health-related quality of life, psychosocial outcomes, psychological distress, life satisfaction, gender differences, cancer treatment side effects
- MeSH terms
- Adaptation, Psychological, Adolescent, Adult, Child, Cross-Sectional Studies, Female, Humans, Male, Neoplasms, Quality of Life, Sexual Behavior, Sexual Dysfunction, Physiological, Sex Factors, Survivors, Young Adult
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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