Taxonomy and function of C1 protein kinase C homology domains

Cited by (375)

Items 201–300 of 375

  1. Protein Kinase C Activators as Synaptogenic and Memory Therapeutics
    Miao‐Kun Sun, Daniel L. Alkon · 2009 · Archiv der Pharmazie
  2. Diacylglycerol kinases: Relationship to other lipid kinases
    Qianqian Ma, Sandra B. Gabelli, Daniel M. Raben · 2018 · Advances in Biological Regulation
  3. Programmed cell death in fission yeast Schizosaccharomyces pombe
    Choon Pei Low, Hongyuan Yang · 2008 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  4. Interaction of the novel anthracycline antitumor agent N-benzyladriamycin-14-valerate with the C1-regulatory domain of protein kinase C: structural requirements, isoform specificity, and correlation with drug cytotoxicity.
    J. Brent Roaten, Marcelo G. Kazanietz, Marı́a J. Caloca, Paul J. Bertics, Leonard Lothstein, Abby L. Parrill, Mervyn Israel, Trevor W. Sweatman · 2002 · PubMed
  5. Identification of Conserved Amino Acids N-terminal of the PKCϵC1b Domain Crucial for Protein Kinase Cϵ-mediated Induction of Neurite Outgrowth
    Mia Ling, Ulrika Trollér, Ruth Zeidman, Helena Stensman, Anna Schultz, Christer U. Larsson · 2005 · Journal of Biological Chemistry
  6. Activation and translocation of PKCδ is necessary for VEGF-induced ERK activation through KDR in HEK293T cells
    Masamitsu Kuriyama, Taizo Taniguchi, Yasuhito Shirai, Atsuo T. Sasaki, Akihiko Yoshimura, Naoaki Saito · 2004 · Biochemical and Biophysical Research Communications
  7. The C2 domain of protein kinase Cα is directly involved in the diacylglycerol-dependent binding of the C1 domain to the membrane
    Pablo Conesa‐Zamora, Juan Carmelo Gómez-Fernández, Senena Corbalán‐García · 2000 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  8. Distinct expression and localization of the type II diacylglycerol kinase isozymes δ, η and κ in the mouse reproductive organs
    Takao Shionoya, Takako Usuki, Suguru Komenoi, Takeshi Isozaki, Hiromichi Sakai, Fumio Sakane · 2015 · BMC Developmental Biology
  9. Design and Synthesis of 8-Octyl-benzolactam-V9, a Selective Activator for Protein Kinase Cε and η
    Yu Nakagawa, Kazuhiro Irie, Ryo C. Yanagita, Hajime Ohigashi, Ken‐ichiro Tsuda, Kaori Kashiwagi, Naoaki Saito · 2006 · Journal of Medicinal Chemistry
  10. Dictyostelium discoideum has a single diacylglycerol kinase gene with similarity to mammalian θ isoforms
    Marc A. de la Roche, Janet L. Smith, Maribel Rico, Silvia Carrasco, Isabel Mérida, Lucila S. Licate, Graham P. Côté, Thomas T. Egelhoff · 2002 · Biochemical Journal
  11. Reactive Cysteine in the Structural Zn2+ Site of the C1B Domain from PKCα
    Mikaela D. Stewart, Tatyana I. Igumenova · 2012 · Biochemistry
  12. Protein Kinase C – Possible Therapeutic Target to Treat Cardiovascular Diseases
    Yamini Saraswathy Bynagari, Ramya Chari, Laurie E. Kilpatrick, Satya P. Kunapuli · 2010 · Cardiovascular & Haematological Disorders - Drug Targets
  13. The effects of acute ethanol administration on ethanol withdrawal-induced anxiety-like syndrome in rats: A biochemical study
    Jaya Kumar, Hermizi Hapidin, Get Bee Yvonne-Τee, Zalina Ismail · 2015 · Alcohol
  14. The Pleckstrin Homology Domain of Diacylglycerol Kinase η Strongly and Selectively Binds to Phosphatidylinositol 4,5-Bisphosphate
    Aiko Kume, Koki Kawase, Suguru Komenoi, Takako Usuki, Ena Takeshita, Hiromichi Sakai, Fumio Sakane · 2016 · Journal of Biological Chemistry
  15. Structural Basis of RasGRP Binding to High-Affinity PKC Ligands
    Suo-Bao Rong, Istvan J. Enyedy, Lixin Qiao, Lianyun Zhao, Dawei Ma, Larry L. Pearce, Patricia S. Lorenzo, James C. Stone, Peter M. Blumberg, Shaomeng Wang et al. · 2002 · Journal of Medicinal Chemistry
  16. Diacylglycerol kinase δ1 transiently translocates to the plasma membrane in response to high glucose
    Masato Takeuchi, Shizuka Sakiyama, Takako Usuki, Hiromichi Sakai, Fumio Sakane · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  17. Diacylglycerol-Stimulated Endocytosis of Transferrin in Trypanosomatids Is Dependent on Tyrosine Kinase Activity
    Sandesh Subramanya, Kojo Mensa‐Wilmot · 2009 · PLoS ONE
  18. PKCη as a therapeutic target in glioblastoma multiforme
    Patrick M Martin, Isa M. Hussaini · 2005 · Expert Opinion on Therapeutic Targets
  19. Diacylglycerols as activators of protein kinase C (Review)
    Juan Carmelo Gómez-Fernández, Alejandro Torrecillas, Senena Corbalán‐García · 2004 · Molecular Membrane Biology
  20. Diacylglycerol kinase ζ regulates RhoA activation via a kinase-independent scaffolding mechanism
    Ryan Ard, Kirk Mulatz, Hanan Abramovici, Jean‐Christian Maillet, Alexandra Fottinger, Tanya Foley, Michèle-Renée Byham, Tasfia Ahmed Iqbal, Atsuko Yoneda, John Couchman et al. · 2012 · Molecular Biology of the Cell
  21. Cellular functions of class IX myosins in epithelia and immune cells
    Martin Bähler, Kerstin Elfrink, Peter J. Hanley, Sabine Thelen, Yan Xu · 2011 · Biochemical Society Transactions
  22. Contributions to Maxima in Protein Kinase C Activation
    Julianne J. Sando, Olga Chertihin, Jonathan M. Owens, Robert H. Kretsinger · 1998 · Journal of Biological Chemistry
  23. Structural Basis for the Failure of the C1 Domain of Ras Guanine Nucleotide Releasing Protein 2 (RasGRP2) to Bind Phorbol Ester with High Affinity
    Ágnes Czikora, Daniel J. Lundberg, Adelle Abramovitz, Nancy E. Lewin, Noémi Kedei, Megan L. Peach, Xiaoling Zhou, Raymond C. Merritt, Elizabeth A. Craft, Derek C. Braun et al. · 2016 · Journal of Biological Chemistry
  24. Modulation of fungal virulence through CRZ1 regulated F-BAR-dependent actin remodeling and endocytosis in chickpea infecting phytopathogen Ascochyta rabiei
    Manisha Sinha, Ankita Shree, Kunal Pratap Singh, Kamal Kumar, Shreenivas Kumar Singh, Vimlesh Kumar, Praveen Kumar Verma · 2021 · PLoS Genetics
  25. Binding Selectivity of Conformationally Restricted Analogues of (−)-Indolactam-V to the C1 Domains of Protein Kinase C Isozymes
    Akiko Masuda, Kazuhiro Irie, Yu Nakagawa, Hajime Ohigashi · 2002 · Bioscience Biotechnology and Biochemistry
  26. Solid-phase synthesis, mass spectrometric analysis of the zinc-folding, and phorbol ester-binding studies of the 116-mer peptide containing the tandem cysteine-rich C1 domains of protein kinase C gamma
    Hiroyuki Fukuda, Kazuhiro Irie, Akifumi Nakahara, Hajime Ohigashi, Paul A. Wender · 1999 · Bioorganic & Medicinal Chemistry
  27. Modeling studies on the structural determinants for the DAG/phorbol ester binding to C1 domain
    Ghazi Mohammad Sayedur Rahman, Joydip Das · 2014 · Journal of Biomolecular Structure and Dynamics
  28. The use of fluorescent phorbol esters in studies of protein kinase C–membrane interactions
    Simon J. Slater, Cojen Ho, Christopher D. Stubbs · 2002 · Chemistry and Physics of Lipids
  29. Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia‐Telangiectasia mutated) null mutant
    Iran Malavazi, Marcela Savoldi, Márcia Eliana da Silva Ferreira, Frederico Marianetti Soriani, Pierina Sueli Bonato, Maria Helena S. Goldman, Gustavo Henrique Goldman · 2007 · Molecular Microbiology
  30. Molecular Basis for Failure of “Atypical” C1 Domain of Vav1 to Bind Diacylglycerol/Phorbol Ester
    Tamás Géczy, Megan L. Peach, Saı̈d El Kazzouli, Dina M. Sigano, Ji‐Hye Kang, Christopher J. Valle, Julia S. Selezneva, Wonhee Woo, Noémi Kedei, Nancy E. Lewin et al. · 2012 · Journal of Biological Chemistry
  31. Diacylglycerol kinase δ associates with receptor for activated C kinase 1, RACK1
    Shin-ichi Imai, Satoshi Yasuda, Masahiro Kai, Hideo Kanoh, Fumio Sakane · 2009 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  32. Diacylglycerol Kinase Malfunction in Human Disease and the Search for Specific Inhibitors
    Isabel Mérida, Javier Arranz‐Nicolás, Pedro Torres‐Ayuso, Antonia Ávila‐Flores · 2019 · Handbook of experimental pharmacology
  33. The amide hydrogen of (−)-indolactam-V and benzolactam-V8’s plays a critical role in protein kinase c binding and tumor-promoting activities
    Yu Nakagawa, Kazuhiro Irie, Yoshimasa Nakamura, Hajime Ohigashi · 2001 · Bioorganic & Medicinal Chemistry Letters
  34. Synthesis and PKC isozyme surrogate binding of indothiolactam-V, a new thioamide analogue of tumor promoting indolactam-V
    Yu Nakagawa, Kazuhiro Irie, Hajime Ohigashi, Hideo Hayashi, Paul A. Wender · 2000 · Bioorganic & Medicinal Chemistry Letters
  35. Synthesis and phorbol ester-binding studies of the individual cysteine-rich motifs of protein Kinase D
    Kazuhiro Irie, Akifumi Nakahara, Hajime Ohigashi, Hiroyuki Fukuda, Paul A. Wender, Hiroaki Konishi, Ushio Kikkawa · 1999 · Bioorganic & Medicinal Chemistry Letters
  36. Characterization of a protein kinase C gene in Sporothrix schenckii and its expression during the yeast-to-mycelium transition
    Edna E. Aquino-Piñero, Nuri Rodrı́guez-del Valle · 2002 · Medical Mycology
  37. Conformationally constrained analogues of diacylglycerol (DAG). 14.1 Dissection of the roles of the sn-1 and sn-2 carbonyls in DAG mimetics by isopharma cophore replacement
    Víctor E. Márquez, Rajiv Sharma, Shaomeng Wang, Nancy E. Lewin, Peter M. Blumberg, In‐Sik Kim, Jeewoo Lee · 1998 · Bioorganic & Medicinal Chemistry Letters
  38. Interfacial Partitioning of a Loop Hinge Residue Contributes to Diacylglycerol Affinity of Conserved Region 1 Domains
    Mikaela D. Stewart, Taylor R. Cole, Tatyana I. Igumenova · 2014 · Journal of Biological Chemistry
  39. Metabolic control of cytosolic‐facing pools of diacylglycerol in budding yeast
    Suriakarthiga Ganesan, Maria Laura Sosa Ponce, Marjan Tavassoli, Brittney N. Shabits, Mark Mahadeo, Elmar J. Prenner, Mauricio R. Terebiznik, Vanina Zaremberg · 2018 · Traffic
  40. The C4 hydroxyl group of phorbol esters is not necessary for protein kinase C binding
    Minoru Tanaka, Kazuhiro Irie, Yu Nakagawa, Yoshimasa Nakamura, Hajime Ohigashi, Paul A. Wender · 2001 · Bioorganic & Medicinal Chemistry Letters
  41. Diacylglycerol kinase η regulates C2C12 myoblast proliferation through the mTOR signaling pathway
    Hiromichi Sakai, Chiaki Murakami, Takako Usuki, Qiang Lü, Kenichi Matsumoto, Takeshi Urano, Fumio Sakane · 2020 · Biochimie
  42. Comparative proteomic analysis of the effects of nitric oxide on alleviating Cd-induced toxicity in rice (Oryza sativa L.)
    Xiufeng Zhao, Chengqiang Ding, Lin Chen, Shaohua Wang, Qiangsheng Wang, Yanfeng Ding · 2012 · Plant Omics
  43. Structural basis of microtubule-mediated signal transduction
    Choi, Sung Ryul, Blum, Thorsten B., Giono, Matteo, Roy, Bibhas, Vakonakis, Ioannis, Schmid, Dominic, Oelgarth, Nicole, Ranganathan, Apisha, Gossert, Alvar D., Shivashankar, G.V. et al. · 2026 · Cell
  44. Protein kinase Cα stimulates hypoxia-induced pulmonary artery smooth muscle cell proliferation in rats through activating the extracellular signal-regulated kinase 1/2 pathway
    Rui Jiang, Yiwei Shi, Chao Zeng, Wenyan Yu, Aizhen Zhang, Yong-cheng Du · 2017 · Molecular Medicine Reports
  45. The atypical PKC scaffold protein P62 is a novel target for anti-inflammatory and anti-cancer therapies.
    J. Moscat, M. Diaz-Meco · 2002 · Advances in Enzyme Regulation
  46. Analysis of the non-covalent interaction between metal ions and the cysteine-Rich domain of protein kinase C eta by electrospray ionization mass spectrometry
    Mayumi Shindo, Kazuhiro Irie, Hiroyuki Fukuda, Hajime Ohigashi · 2003 · Bioorganic & Medicinal Chemistry
  47. PKC1, encoding a protein kinase C, and FAT1, encoding a fatty acid transporter protein, are neighbors in Cochliobolus heterostrophus
    Birgitt Oeser · 1998 · FEMS Microbiology Letters
  48. DGK-θ: Structure, Enzymology, and Physiological Roles
    Becky Tu‐Sekine, Hana L. Goldschmidt, Daniel M. Raben · 2016 · Frontiers in Cell and Developmental Biology
  49. Individual C1 domains of PKD3 in phorbol ester-induced plasma membrane translocation of PKD3 in intact cells
    Gülsüm Anderson, Jun Chen, Qiming Jane Wang · 2005 · Cellular Signalling
  50. Structural Zinc Sites
    David S. Auld · 2004 · Handbook of Metalloproteins
  51. Discovery of the Selective Protein Kinase C-θ Kinase Inhibitor, CC-90005
    Patrick Papa, Brandon Whitefield, Deborah S. Mortensen, Dan Cashion, Dehua Huang, Eduardo Torres, Jason A. Parnes, John Sapienza, Joshua D. Hansen, Matthew Correa et al. · 2021 · Journal of Medicinal Chemistry
  52. Upstream and downstream pathways of diacylglycerol kinase : Novel phosphatidylinositol turnover-independent signal transduction pathways
    Fumio Sakane, Chiaki Murakami, Hiromichi Sakai · 2024 · Advances in Biological Regulation
  53. Protein kinase C family evolution in jawed vertebrates
    Adrián García-Concejo, Dan Larhammar · 2021 · Developmental Biology
  54. The lipid second messenger diacylglycerol as a negative regulator of Rac signalling.
    H. Wang, M. Kazanietz · 2006 · Biochemical Society Transactions
  55. Role of Protein Kinase C in Eosinophil Function
    Takafumi N. Yamaguchi, Masato Suzuki, Hirokazu Kimura, Masahiko Katô · 2006 · Allergology International
  56. Vitamin A as PKC Co-factor and Regulator of Mitochondrial Energetics
    Ulrich Hämmerling · 2016 · Sub-cellular biochemistry/Subcellular biochemistry
  57. Subcellular localization of Rap1 GTPase activator CalDAG‐GEFI is orchestrated by interaction of its atypical C1 domain with membrane phosphoinositides
    Muzaddid Sarker, Ardeshir Goliaei, Florence Golesi, Marjorie Poggi, Aaron A. Cook, M. Ashhar I. Khan, Brenda R. S. Temple, Lucia Stefanini, Matthias Canault, Wolfgang Bergmeier et al. · 2019 · Journal of Thrombosis and Haemostasis
  58. Comparison of the PKCα and the PKCε C1b Domains: Identification of Residues Critical for PKCε-mediated Neurite Induction
    Mia Ling, Lovisa Sunesson, Christer U. Larsson · 2007 · Journal of Molecular Biology
  59. Protein Kinase C Protocols
    Alexandra C. Newton · 2003 · Humana Press eBooks
  60. Diacylglycerol kinase δ controls down-regulation of cyclin D1 for C2C12 myogenic differentiation
    Hiromichi Sakai, Chiaki Murakami, Kenichi Matsumoto, Takeshi Urano, Fumio Sakane · 2018 · Biochimie
  61. Evidence for a role of MRCK in mediating HeLa cell elongation induced by the C1 domain ligand HMI-1a3
    Virpi Talman, Gergana Gateva, Marja Ahti, Elina Ekokoski, Pekka Lappalainen, Raimo K. Tuominen · 2014 · European Journal of Pharmaceutical Sciences
  62. Osmotic shock-dependent redistribution of diacylglycerol kinase η1 to non-ionic detergent-resistant membrane via pleckstrin homology and C1 domains
    Daisuke Matsutomo, Takeshi Isozaki, Hiromichi Sakai, Fumio Sakane · 2012 · The Journal of Biochemistry
  63. Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP
    Eleonora Elhalem, Lucía Gandolfi Donadio, Xiaoling Zhou, Nancy E. Lewin, Lia C. García, Christopher Cong Lai, James A. Kelley, Megan L. Peach, Peter M. Blumberg, Maria Julieta Comin · 2017 · Bioorganic & Medicinal Chemistry
  64. Phosphorylation and dephosphorylation: Protein kinases A and C
    B. Gomperts, I. Kramer, P. E. Tatham · 2002 · Elsevier eBooks
  65. N‐Methyl‐Substituted Fluorescent DAG–Indololactone Isomers Exhibit Dramatic Differences in Membrane Interactions and Biological Activity
    Noga Gal, Sofiya Kolusheva, Noémi Kedei, Andrea Telek, Taiyabah A. Naeem, Nancy E. Lewin, Langston Lim, Poonam Mannan, Susan H. Garfield, Saı̈d El Kazzouli et al. · 2011 · ChemBioChem
  66. Toggling of Diacylglycerol Affinity Correlates with Conformational Plasticity in C1 Domains
    Mikaela D. Stewart, Tatyana I. Igumenova · 2017 · Biochemistry
  67. Phylogenetic analysis of the diacylglycerol kinase family of proteins and identification of multiple highly-specific conserved inserts and deletions within the catalytic domain that are distinctive characteristics of different classes of DGK homologs
    Radhey S. Gupta, Richard M. Epand · 2017 · PLoS ONE
  68. Structural insights into C1-ligand interactions: Filling the gaps by in silico methods
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  69. Diacylglycerol kinase γ is a novel anionic phospholipid binding protein with a selective binding preference
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  70. Expression, Purification, and Characterization of Human Diacylglycerol Kinase ζ
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  71. Recombinant C1b domain of PKCδ triggers meiotic maturation upon microinjection in Xenopus laevis oocytes
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  72. Design and physicochemical properties of new fluorescent ligands of protein kinase C isozymes focused on CH/π interaction
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  73. Inhibitors of Protein Kinase C and Related Receptors for the Lipophilic Second-Messenger sn-1,2-Diacylglycerol
    Peter M. Blumberg, Peter Istvan Acs, Dipak Kr. Bhattacharyya, Patricia S. Lorenzo · 2000 · Humana Press eBooks
  74. Class Ix Myosins
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  75. Analytical Method for Diacylglycerol Kinase ζ Activity in Cells Using Protein Myristoylation and Liquid Chromatography–Tandem Mass Spectrometry
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  76. Elusive structure of mammalian DGKs
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  77. Saturated fatty acid– and/or monounsaturated fatty acid–containing phosphatidic acids selectively interact with heat shock protein 27
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  78. Diacylglycerol kinase ζ interacts with sphingomyelin synthase 1 and sphingomyelin synthase‐related protein via different regions
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  79. Phorbol ester and hydrogen peroxide synergistically induce the interaction of diacylglycerol kinase γ with the Src homology 2 and C1 domains of β2-chimaerin
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  80. Possible enhancing activity of diacylglycerol on 4-nitroquinoline 1-oxide induced carcinogenesis of the tongue in human c-Ha-ras proto-oncogene transgenic rats
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  82. Phosphorylation and dephosphorylation
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  83. CR4056, a powerful analgesic imidazoline‐2 receptor ligand, inhibits the inflammation‐induced PKCε phosphorylation and membrane translocation in sensory neurons
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  85. Regulation of calcium-dependent [3H]noradrenaline release from rat cerebrocortical synaptosomes by protein kinase C and modulation of the actin cytoskeleton
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  86. Two-Dimensional Crystal Structures of Protein Kinase C-δ, Its Regulatory Domain, and the Enzyme Complexed with Myelin Basic Protein
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  88. Charge Density Influences C1 Domain Ligand Affinity and Membrane Interactions
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  90. Diacylglycerol Lactones Targeting the Structural Features That Distinguish the Atypical C1 Domains of Protein Kinase C ζ and ι from Typical C1 Domains
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  94. Regulation of Conventional and Novel Protein Kinase C Isozymes by Phosphorylation and Lipids
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  95. Protein Kinase C in Oncogenic Transformation and Cell Polarity
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  96. Relevance of Atypical Protein Kinase C Isotypes to the Drug Discovery Process
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  100. Temperature-Dependent Expression of a CFP-YFP FRET Diacylglycerol Sensor Enables Multiple-Read Screening for Compounds That Affect C1 Domains
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