Piperine: A review of its biological effects

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Targeting breast stem cells with the cancer preventive compounds curcumin and piperine

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Biological role of Piper nigrum L. (Black pepper): A review

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Piper nigrum and Piperine: An Update

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Intranasal Piperine-Loaded Chitosan Nanoparticles as Brain-Targeted Therapy in Alzheimer's Disease: Optimization, Biological Efficacy, and Potential Toxicity

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Co-delivery of curcumin and piperine in zein-carrageenan core-shell nanoparticles: Formation, structure, stability and in vitro gastrointestinal digestion

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Piperine, the main alkaloid of Thai black pepper, protects against neurodegeneration and cognitive impairment in animal model of cognitive deficit like condition of Alzheimer’s disease

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A comprehensive review of the health perspectives of resveratrol

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Marine-sourced anti-cancer and cancer pain control agents in clinical and late preclinical development

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Piperine inhibits the growth and motility of triple-negative breast cancer cells

Greenshields, A. L., Doucette, C. D., Sutton, K. M., Madera, L., Annan, H. G., Yaffe, P. B., Knickle, A. F., Dong, Z., & Hoskin, D. W. (2014) · Cancer Letters · doi:10.1016/j.canlet.2014.11.017 · Cited by 224

Piperine as an inhibitor of Rv1258c, a putative multidrug efflux pump of Mycobacterium tuberculosis

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Revisiting the ABCs of Multidrug Resistance in Cancer Chemotherapy

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Piperine, an alkaloid from black pepper, inhibits growth of human colon cancer cells via G1 arrest and apoptosis triggered by endoplasmic reticulum stress

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Effects of resveratrol alone or in combination with piperine on cerebral blood flow parameters and cognitive performance in human subjects: a randomised, double-blind, placebo-controlled, cross-over investigation

Wightman, E. L., Reay, J. L., Haskell‐Ramsay, C. F., Williamson, G., Dew, T. P., & Kennedy, D. O. (2014) · British Journal Of Nutrition · doi:10.1017/s0007114514000737 · Cited by 176

Preparation, characterization,in vivoand biochemical evaluation of brain targeted Piperine solid lipid nanoparticles in an experimentally induced Alzheimer’s disease model

Yusuf, M., Khan, M., Khan, R. A., & Ahmed, B. (2012) · Journal of drug targeting · doi:10.3109/1061186x.2012.747529 · Cited by 174

Piperine and Its Role in Chronic Diseases

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Therapeutic potential of oxadiazole or furadiazole containing compounds

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Studies on the in vitro absorption of spice principles – Curcumin, capsaicin and piperine in rat intestines

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Co-delivery of rapamycin- and piperine-loaded polymeric nanoparticles for breast cancer treatment

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Blood Pressure Lowering and Vasomodulator Effects of Piperine

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Piperine, the potential functional food for mood and cognitive disorders

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Anti-apoptotic and Anti-inflammatory effect of Piperine on 6-OHDA induced Parkinson's Rat model

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Investigation of the antibacterial activity and efflux pump inhibitory effect of co-loaded piperine and gentamicin nanoliposomes in methicillin-resistantStaphylococcus aureus

Khameneh, B., Iranshahy, M., Ghandadi, M., Atashbeyk, D. G., Bazzaz, B. S. F., & Iranshahi, M. (2014) · Drug Development and Industrial Pharmacy · doi:10.3109/03639045.2014.920025 · Cited by 143

Piperine Attenuates Pathological Cardiac Fibrosis Via PPAR-γ/AKT Pathways

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Piperine production by endophytic fungus Periconia sp. Isolated from Piper longum L.

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Piperine inhibits IL-β induced expression of inflammatory mediators in human osteoarthritis chondrocyte

Ying, X., Chen, X., Cheng, S., Shen, Y. L., Peng, L., & Xu, H. Z. (2013) · International Immunopharmacology · doi:10.1016/j.intimp.2013.06.025 · Cited by 138

Acute and subacute toxicity of piperine in mice, rats and hamsters

Piyachaturawat, P., Glinsukon, T., & Toskulkao, C. (1983) · Toxicology Letters · doi:10.1016/0378-4274(83)90198-4 · Cited by 136

Cepharanthine and Piperine ameliorate diabetic nephropathy in rats: role of NF-κB and NLRP3 inflammasome

Samra, Y. A., Said, H. S., Elsherbiny, N. M., Liou, G. I., El‐Shishtawy, M. M., & Eissa, L. A. (2016) · Life Sciences · doi:10.1016/j.lfs.2016.06.002 · Cited by 135

Piperidine alkaloids from Piper retrofractum Vahl. protect against high-fat diet-induced obesity by regulating lipid metabolism and activating AMP-activated protein kinase

Kim, K. J., Lee, M.-S., Jo, K., & Hwang, J. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.06.153 · Cited by 132

Piperine inhibits eosinophil infiltration and airway hyperresponsiveness by suppressing T cell activity and Th2 cytokine production in the ovalbumin-induced asthma model

Kim, S., & Lee, Y. (2009) · Journal of Pharmacy and Pharmacology · doi:10.1211/jpp.61.03.0010 · Cited by 126

Piperine inhibits proliferation of human osteosarcoma cells via G2/M phase arrest and metastasis by suppressing MMP-2/-9 expression

Zhang, J., Zhu, X., Li, H., Li, B., Sun, L., Xie, T., Zhu, T., Zhou, H., & Ye, Z. (2014) · International Immunopharmacology · doi:10.1016/j.intimp.2014.11.012 · Cited by 122

Co‐administration of piperine and docetaxel results in improved anti‐tumor efficacy via inhibition of CYP3A4 activity

Makhov, P. B., Golovine, K. V., Canter, D. J., Kutikov, A., Simhan, J., Corlew, M. M., Uzzo, R. G., & Kolenko, V. M. (2011) · The Prostate · doi:10.1002/pros.21469 · Cited by 120

Effect of piperine on inhibition of FFA induced TLR4 mediated inflammation and amelioration of acetic acid induced ulcerative colitis in mice

Gupta, R. A., Motiwala, M. N., Dumore, N. G., Danao, K. R., & Ganjare, A. B. (2015) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2015.01.039 · Cited by 118

Piperine inhibits LPS induced expression of inflammatory mediators in RAW 264.7 cells

Ying, X., Yu, K., Chen, X., Chen, H., Hong, J., Cheng, S., & Peng, L. (2013) · Cellular Immunology · doi:10.1016/j.cellimm.2013.09.001 · Cited by 116

Piperine ameliorates oxidative stress, inflammation and histological outcome in collagen induced arthritis

Umar, S., Golam Sarwar, A. H. M., Umar, K., Ahmad, N., Sajad, M., Ahmad, S., Katiyar, C. K., & Khan, H. A. (2013) · Cellular Immunology · doi:10.1016/j.cellimm.2013.07.004 · Cited by 107

Neuroprotective effects of piperine on the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease mouse model

Yang, W., Chen, Y., Liu, H., & Qu, H. (2015) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2015.2356 · Cited by 106

Piperine reverses high fat diet-induced hepatic steatosis and insulin resistance in mice

Choi, S., Choi, Y., Choi, Y., Kim, S., Jang, J., & Park, T. (2013) · Food Chemistry · doi:10.1016/j.foodchem.2013.06.028 · Cited by 105

Curcuminoids plus piperine improve nonalcoholic fatty liver disease: A clinical trial

Panahi, Y., Valizadegan, G., Ahamdi, N., Ganjali, S., Majeed, M. A., & Sahebkar, A. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.28877 · Cited by 104

Mitigating efficacy of piperine in the physiological derangements of high fat diet induced obesity in Sprague Dawley rats

Parim, B., Nemani, H., Meriga, B., Mehar, S. K., Potana, S., & Ramgopalrao, S. (2014) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2014.07.008 · Cited by 102

Neuroprotective Effect of Quercetin in Combination with Piperine Against Rotenone- and Iron Supplement–Induced Parkinson’s Disease in Experimental Rats

Sharma, S., Aran, K. R., & Singh, S. (2019) · Neurotoxicity Research · doi:10.1007/s12640-019-00120-z · Cited by 102

Piperine, a Component of Black Pepper, Inhibits Adipogenesis by Antagonizing PPARγ Activity in 3T3-L1 Cells

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Effect of piperine in the regulation of obesity-induced dyslipidemia in high-fat diet rats

Shah, S., Shah, G. B., Singh, S., Gohil, P., Chauhan, K., Shah, K. A., & Chorawala, M. R. (2011) · Indian Journal of Pharmacology · doi:10.4103/0253-7613.81516 · Cited by 100

Piperine: Old Spice and New Nutraceutical?

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Spice up the hypertension diet - curcumin and piperine prevent remodeling of aorta in experimental L-NAME induced hypertension

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Piperine as an inhibitor of the MdeA efflux pump of Staphylococcus aureus

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Piperine: role in prevention and progression of cancer

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Anticonvulsant mechanisms of piperine, a piperidine alkaloid

Mishra, A., Punia, J. K., Bladen, C., Zamponi, G. W., & Goel, R. K. (2015) · Channels · doi:10.1080/19336950.2015.1092836 · Cited by 94

Protective efficacy of piperine against Mycobacterium tuberculosis

Sharma, S., Kalia, N. P., Suden, P., Chauhan, P. S., Kumar, M., Ram, A. B., Khajuria, A., Bani, S., & Khan, I. A. (2014) · Tuberculosis · doi:10.1016/j.tube.2014.04.007 · Cited by 89

Piperine-loaded nanoparticles with enhanced dissolution and oral bioavailability for epilepsy control

Ren, T., Hu, M., Cheng, Y., Shek, T. L., Xiao, M., Ho, N. J., Zhang, C., Leung, S. S. Y., & Zuo, Z. (2019) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2019.104988 · Cited by 89

The analgesic and anticonvulsant effects of Piperine in mice

Al-Humayyd, M. S., Bukhari, I. A., Mahesar, A. L., & Gilani, A. H. (2013) · The FASEB Journal · doi:10.1096/fasebj.27.1_supplement.660.5 · Cited by 88

Piperine, a Natural Bioenhancer, Nullifies the Antidiabetic and Antioxidant Activities of Curcumin in Streptozotocin-Diabetic Rats

Arcaro, C. A., Gutierres, V. O., Assis, R. P., Moreira, T. F., da Costa, P. I., Baviera, A. M., & Brunetti, I. L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0113993 · Cited by 86

Anti-cancer effects of Piper nigrum via inducing multiple molecular signaling in vivo and in vitro

Deng, Y., Sriwiriyajan, S., Tedasen, A., Hiransai, P., & Graidist, P. (2016) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2016.04.047 · Cited by 86

Antitumor and Apoptosis-inducing Effects of Piperine on Human Melanoma Cells

Yoo, E. S., Choo, G. S., Kim, S. H., Woo, J., Kim, H. J., Park, Y. S., KIM, B. S., Kim, S. K., Park, B. K., Cho, S. D., et al. (2019) · Anticancer Research · doi:10.21873/anticanres.13296 · Cited by 86

In vivo effect of piperine on serum and tissue glycoprotein levels in benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice

Selvendiran, K., Singh, J. P. V., & Sakthisekaran, D. (2005) · Pulmonary Pharmacology & Therapeutics · doi:10.1016/j.pupt.2005.04.002 · Cited by 85

Piperine decreases pilocarpine-induced convulsions by GABAergic mechanisms

da Cruz, G. M. P., Felipe, C. F. B., Scorza, F. A., da Costa, M. A. C., Tavares, A. F., Menezes, M. L. F., de Andrade, G. M., Leal, L. K. A. M., Brito, G. A. D. C., Naffah‐Mazzacoratti, M. D. G., et al. (2013) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.01.002 · Cited by 84

Piper nigrum ethanolic extract rich in piperamides causes ROS overproduction, oxidative damage in DNA leading to cell cycle arrest and apoptosis in cancer cells

Grinevicius, V. M. A. S., Kviecinski, M. R., Mota, N. S. R. S., Ourique, F., Castro, L. S. E. P. W., Andreguetti, R. R., Correia, J. F. G., Filho, D. W., Pich, C. T., & Pedrosa, R. C. (2016) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2016.05.020 · Cited by 84

Curcuminoids Plus Piperine Modulate Adipokines in Type 2 Diabetes Mellitus

Panahi, Y., Khalili, N., Sahebi, E., Namazi, S., Atkin, S. L., Majeed, M. A., & Sahebkar, A. (2018) · Current Clinical Pharmacology · doi:10.2174/1574884713666180104095641 · Cited by 83

Cytoprotective and immunomodulating properties of piperine on murine splenocytes: An in vitro study

Pathak, N., & Khandelwal, S. (2007) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.07.033 · Cited by 82

Piperine exerts anti-seizure effects via the TRPV1 receptor in mice

Chen, C.-Y., Li, W., Qu, K., & Chen, C.-R. (2013) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2013.07.041 · Cited by 82

Antiallergic effect of piperine on ovalbumin-induced allergic rhinitis in mice

Aswar, U. M., Shintre, S., Chepurwar, S., & Aswar, M. K. (2015) · Pharmaceutical Biology · doi:10.3109/13880209.2014.982299 · Cited by 78

Piperine inhibits IL-1β-induced IL-6 expression by suppressing p38 MAPK and STAT3 activation in gastric cancer cells

Xia, Y., Khoi, P. N., Yoon, H. J., Lian, S., Joo, Y., Chay, K.-O., Kim, K. K., & Jung, Y. D. (2014) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-014-2214-0 · Cited by 77

Chemoprevention of Prostate Cancer by Natural Agents: Evidence from Molecular and Epidemiological Studies

Mokbel, K., Wazir, U., & Mokbel, K. (2019) · Anticancer Research · doi:10.21873/anticanres.13720 · Cited by 77

Synergistic effect of curcumin and piperine in suppression of DENA-induced hepatocellular carcinoma in rats

Patial, V., Mahesh, S., Sharma, S., Pratap, K., Singh, D., & Padwad, Y. S. (2015) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2015.07.012 · Cited by 76

The analgesic and anticonvulsant effects of piperine in mice.

Bukhari, I. A., Pivac, N., Alhumayyd, M. S., Mahesar, A. L., & Gilani, A. H. (2013) · PubMed · Cited by 76

Effects of piperine on testis of albino rats

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Anti‐Inflammatory Effects of Capsaicin and Piperine on Helicobacter pylori‐Induced Chronic Gastritis in Mongolian Gerbils

Toyoda, T., Shi, L., Takasu, S., Cho, Y., Kiriyama, Y., Nishikawa, A., Ogawa, K., Tatematsu, M., & Tsukamoto, T. (2015) · Helicobacter · doi:10.1111/hel.12243 · Cited by 72

The protective effect of piperine on dextran sulfate sodium induced inflammatory bowel disease and its relation with pregnane X receptor activation

Hu, D., Wang, Y., Chen, Z., Ma, Z.-C., You, Q., Zhang, X., Liang, Q., Tan, H.-L., Xiao, C., Tang, X., et al. (2015) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2015.04.006 · Cited by 70

Immunotoxicological effects of piperine in mice

DOGRA, R. K. S., Khanna, S., & Shanker, R. (2004) · Toxicology · doi:10.1016/j.tox.2003.10.006 · Cited by 70

Inhibition of monoamine oxidase by derivatives of piperine, an alkaloid from the pepper plant Piper nigrum, for possible use in Parkinson’s disease

Al-Baghdadi, O. B., Prater, N. I., der Schyf, C. J. V., & Geldenhuys, W. J. (2012) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2012.09.056 · Cited by 69

The plant alkaloid piperine as a potential inhibitor of ethidium bromide efflux in Mycobacterium smegmatis

Jin, J., Zhang, J., Guo, N., Feng, H., Li, L., Liang, J., Sun, K., Wu, X., Wang, X., Liu, M., et al. (2010) · Journal of Medical Microbiology · doi:10.1099/jmm.0.025734-0 · Cited by 69

Cardioprotective effect of curcumin and piperine combination against cyclophosphamide-induced cardiotoxicity

Chakraborty, M., Bhattacharjee, A., & Kamath, J. V. (2017) · Indian Journal of Pharmacology · doi:10.4103/0253-7613.201015 · Cited by 69

Reproductive Toxicity of Piperine in Swiss Albino Mice

Daware, M., Mujumdar, A. M., & Ghaskadbi, S. (2000) · Planta Medica · doi:10.1055/s-2000-8560 · Cited by 68

Effect of piperine on the epididymis of adult male rats

D’Cruz, S. C., & Mathur, P. P. (2005) · Asian Journal of Andrology · doi:10.1111/j.1745-7262.2005.00059.x · Cited by 67

Piperine modulates isoproterenol induced myocardial ischemia through antioxidant and anti-dyslipidemic effect in male Wistar rats

Dhivya, V., Priya, L. B., Chirayil, H. T., Sathiskumar, S., Huang, C., & Padma, V. V. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.01.002 · Cited by 67

Immunomodulatory role of piperine in cadmium induced thymic atrophy and splenomegaly in mice

Pathak, N., & Khandelwal, S. (2009) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2009.02.003 · Cited by 64

Curcumin and piperine abrogate lipid and protein oxidation induced by d-galactose in rat brain

Banji, D., Banji, O. J. F., Dasaroju, S., & Kranthi Kumar, C. H. (2013) · Brain Research · doi:10.1016/j.brainres.2013.03.023 · Cited by 64

Piperine Plays an Anti‐Inflammatory Role inStaphylococcus aureusEndometritis by Inhibiting Activation of NF‐κB and MAPK Pathways in Mice

Zhai, W., Zhang, Z., Xu, N.-N., Guo, Y., Qiu, C., Li, C.-Y., Deng, G., & Guo, M. (2016) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2016/8597208 · Cited by 64

Piperine Augments the Protective Effect of Curcumin Against Lipopolysaccharide-Induced Neurobehavioral and Neurochemical Deficits in Mice

Jangra, A., Kwatra, M., Singh, T., Pant, R., Kushwah, P., Sharma, Y., Saroha, B., Datusalia, A. K., & Bezbaruah, B. K. (2016) · Inflammation · doi:10.1007/s10753-016-0332-4 · Cited by 63

Anticancer and Cancer Prevention Effects of Piperine-Free Piper nigrum Extract on N-nitrosomethylurea-Induced Mammary Tumorigenesis in Rats

Sriwiriyajan, S., Tedasen, A., Lailerd, N., Boonyaphiphat, P., Nitiruangjarat, A., Deng, Y., & Graidist, P. (2015) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-15-0127 · Cited by 62

Piperine Attenuates Cardiovascular, Liver and Metabolic Changes in High Carbohydrate, High Fat-Fed Rats

Diwan, V., Poudyal, H., & Brown, L. (2011) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-011-9306-1 · Cited by 60

Screening of antidiabetic and antihyperlipidemic potential of oil fromPiper longumand piperine with their possible mechanism

Kumar, S. G., Sharma, S., & Vasudeva, N. (2013) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2013.815725 · Cited by 60

A rapid method for isolation of piperine from the fruits of Piper nigrum Linn.

Kanaki, N., Dave, M., Padh, H., & Rajani, M. (2008) · Journal of Natural Medicines · doi:10.1007/s11418-008-0234-3 · Cited by 58

Piperine’s mitigation of obesity and diabetes can be explained by its up-regulation of the metabolic rate of resting muscle

Nogara, L., Naber, N. I., Pate, E., Canton, M., Reggiani, C., & Cooke, R. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1607536113 · Cited by 58

Evaluation of the effect of piperine per se on blood glucose level in alloxan-induced diabetic mice.

Atal, S., Agrawal, R., Vyas, S., Phadnis, P., & Rai, N. (2012) · PubMed · Cited by 57

A combined treatment of curcumin, piperine, and taurine alters the circulating levels of IL-10 and miR-21 in hepatocellular carcinoma patients: a pilot study

Hatab, H. M., Hamid, F. F. A., Soliman, A. F., Al‐Shafie, T. A., Ismail, Y. M., & El-Houseini, M. E. (2019) · Journal of Gastrointestinal Oncology · doi:10.21037/jgo.2019.03.07 · Cited by 57

Black pepper constituent piperine: Genotoxicity studies in vitro and in vivo

Thiel, A., Buskens, C. A. F., Woehrle, T., Etheve, S., Schoenmakers, A., Fehr, M., & Beilstein, P. (2014) · Food and Chemical Toxicology · doi:10.1016/j.fct.2014.01.056 · Cited by 55

Immunomodulatory role of piperine in deltamethrin induced thymic apoptosis and altered immune functions

Kumar, A., Sasmal, D., & Sharma, N. (2015) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2014.12.021 · Cited by 54

Bio-enhancing effect of Piperine with Metformin on lowering blood glucose level in Alloxan induced diabetic mice

Atal, S., Atal, S., Vyas, S., & Phadnis, P. (2016) · Pharmacognosy Research · doi:10.4103/0974-8490.171096 · Cited by 53

Quercetin along with piperine prevents cognitive dysfunction, oxidative stress and neuro-inflammation associated with mouse model of chronic unpredictable stress

Rinwa, P., & Kumar, A. (2013) · Archives of Pharmacal Research · doi:10.1007/s12272-013-0205-4 · Cited by 52

Piperine Promotes Glucose Uptake through ROS‐Dependent Activation of the CAMKK/AMPK Signaling Pathway in Skeletal Muscle

Maeda, A., Shirao, T., Shirasaya, D., Yoshioka, Y., Yamashita, Y., Akagawa, M., & Ashida, H. (2018) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201800086 · Cited by 52

Natural Alkaloids Intervening the Insulin Pathway: New Hopes for Anti-Diabetic Agents?

Christodoulou, M., Tchoumtchoua, J., Skaltsounis, A., Scorilas, A., & Halabalaki, M. (2018) · Current Medicinal Chemistry · doi:10.2174/0929867325666180430152618 · Cited by 52

Antiparasitic efficacy of piperine against Argulus spp. on Carassius auratus (Linn. 1758): in vitro and in vivo study

Kumar, A., Raman, R. P., Kumar, K., Pandey, P. K., Kumar, V., Mohanty, S., & Kumar, S. (2012) · Parasitology Research · doi:10.1007/s00436-012-3054-z · Cited by 51

Increased Oral Bioavailability of Piperine from an Optimized Piper nigrum Nanosuspension

Zafar, F., Jahan, N., Bhatti, H. N., & Khalil-Ur-Rahman (2018) · Planta Medica · doi:10.1055/a-0759-2208 · Cited by 51

Piperine Inhibits the Activities of Platelet Cytosolic Phospholipase A2 and Thromboxane A2 Synthase without Affecting Cyclooxygenase-1 Activity: Different Mechanisms of Action Are Involved in the Inhibition of Platelet Aggregation and Macrophage Inflammatory Response

Son, D., Akiba, S., Hong, J. T., Yun, Y., Hwang, S., Park, Y., & Lee, S. (2014) · Nutrients · doi:10.3390/nu6083336 · Cited by 50

Piperine inhibit inflammation, alveolar bone loss and collagen fibers breakdown in a rat periodontitis model

Dong, Y., Huihui, Z., & Li, C. (2015) · Journal of Periodontal Research · doi:10.1111/jre.12262 · Cited by 50

Piperine regulates glycogen synthase kinase-3β-related signaling and attenuates cognitive decline in D-galactose-induced aging mouse model

Wang, C., Cai, Z.-X., Wang, W., Wei, M., Si, X., Shang, Y., Yang, Z., Li, T., Guo, H., & Li, S. (2019) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2019.108261 · Cited by 50

Curcumin and piperine supplementation of obese mice under caloric restriction modulates body fat and interleukin-1β

Miyazawa, T., Nakagawa, K., Kim, S. H., Thomas, M. J., Paul, L., Zingg, J.-M., Dolnikowski, G. G., Roberts, S. B., Kimura, F., Miyazawa, T., et al. (2018) · Nutrition & Metabolism · doi:10.1186/s12986-018-0250-6 · Cited by 47

Antioxidant, anti-TB activities, phenolic and amide contents of standardised extracts ofPiper sarmentosumRoxb

Hussain, K., Ismail, Z., Sadikun, A., & Ibrahim, P. (2009) · Natural Product Research · doi:10.1080/14786410801987597 · Cited by 46

Characterization of a new rat urinary metabolite of piperine by LC/NMR/MS studies

Bajad, S. U., Coumar, M. S., Khajuria, R. K., Suri, O. P., & Bedi, K. L. (2003) · European Journal of Pharmaceutical Sciences · doi:10.1016/s0928-0987(03)00143-x · Cited by 45

Novel Piperine Derivatives with Antidiabetic Effect as PPAR‐γ Agonists

Kharbanda, C., Alam, M. S., Hamid, H., Javed, K., Bano, S., Ali, Y., Dhulap, A., Alam, P., & Pasha, M. A. Q. (2016) · Chemical Biology & Drug Design · doi:10.1111/cbdd.12760 · Cited by 44

Binding of bioactive phytochemical piperine with human serum albumin: A spectrofluorometric study

Suresh, D., Gangadhariah, M. H., Rao, A. G. A., & Srinivasan, K. (2007) · Biopolymers · doi:10.1002/bip.20735 · Cited by 43

Piperine Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via Modulating NF-κB Signaling Pathways

Lü, Y., Liu, J., Li, H., & Gu, L.-N. (2015) · Inflammation · doi:10.1007/s10753-015-0250-x · Cited by 41

Piperine metabolically regulates peritoneal resident macrophages to potentiate their functions against bacterial infection

Pan, H., Xu, L., Huang, M.-Y., Zha, Q., Zhao, G., Hou, X.-F., Shi, Z., Lin, Q.-R., Ouyang, D., & He, X. (2015) · Oncotarget · doi:10.18632/oncotarget.5957 · Cited by 41

Piperine alleviates osteoclast formation through the p38/c‐ F os/ NFAT c1 signaling axis

Deepak, V., Kruger, M. C., Joubert, A. M., & Coetzee, M. (2015) · BioFactors · doi:10.1002/biof.1241 · Cited by 41

Antimicrobial and Antiproliferative Activities of Black Pepper (Piper nigrum L.) Essential Oil and Oleoresin

Morsy, N. F. S., & El-Salam, E. A. E.-S. A. (2017) · Journal of Essential Oil Bearing Plants · doi:10.1080/0972060x.2017.1341342 · Cited by 41

Antioxidant and hepatoprotective effects of mixed micellar lipid formulation of phyllanthin and piperine in carbon tetrachloride-induced liver injury in rodents

Sethiya, N. K., Shah, P., Rajpara, A., Nagar, P. A., & Mishra, S. H. (2015) · Food & Function · doi:10.1039/c5fo00947b · Cited by 40

Piperine, a plant alkaloid of the piper species, enhances the bioavailability of aflatoxin B1 in rat tissues

Allameh, A., Saxena, M., Biswas, G., Raj, H. G., Singh, J., & Srivastava, N. (1992) · Cancer Letters · doi:10.1016/0304-3835(92)90287-6 · Cited by 40

Piperine Reverses Chronic Unpredictable Mild Stress-Induced Behavioral and Biochemical Alterations in Rats

Mao, Q., Huang, Z., Zhong, X., Xian, Y., & Ip, S. (2014) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-014-0025-1 · Cited by 40

Piperine prevents cholesterol gallstones formation in mice

Song, X., Xu, S., Hu, J., Tang, J., Chu, S., Liu, H., Han, N., Li, J., Zhang, D., Li, Y., et al. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.01.038 · Cited by 39

Piperine as an adjuvant increases the efficacy of curcumin in mitigating benzo(a)pyrene toxicity

Sehgal, A. K., Kumar, M., Jain, M., & Dhawan, D. (2011) · Human & Experimental Toxicology · doi:10.1177/0960327111421943 · Cited by 39

In vitro cytotoxic and in silico activity of piperine isolated from Piper nigrum fruits Linn

Paarakh, P. M., Sreeram, D. C., D, S. S., & Ganapathy, S. (2015) · In Silico Pharmacology · doi:10.1186/s40203-015-0013-2 · Cited by 37

Preliminary study on inhibition of genotoxicity by piperine in mice

Selvendiran, K., Padmavathi, R., Magesh, V., & Sakthisekaran, D. (2005) · Fitoterapia · doi:10.1016/j.fitote.2005.03.016 · Cited by 37

Piperine Is a Mechanism-Based Inactivator of CYP3A

Cui, T., Wang, Q., Tian, X., Zhang, K., Peng, Y., & Zheng, J. (2020) · Drug Metabolism and Disposition · doi:10.1124/dmd.119.088955 · Cited by 37

Piperine Alleviates Doxorubicin-Induced Cardiotoxicity via Activating PPAR- γ in Mice

Yan, J., Xu, S., Kong, C., Zhou, X., Bian, Z., Yan, L., & Tang, Q. (2019) · PPAR Research · doi:10.1155/2019/2601408 · Cited by 37

Piperine mediates LPS induced inflammatory and catabolic effects in rat intervertebral disc.

Li, Y., Li, K., Hu, Y., Xu, B., & Zhao, J. (2015) · Europe PMC (PubMed Central) · Cited by 36

Hypolipidemic effects of a new piperine derivative GB-N fromPiper longumin high-fat diet-fed rats

Bao, L., Bai, S., & Gereltu, B. (2012) · Pharmaceutical Biology · doi:10.3109/13880209.2012.654395 · Cited by 36

Diverged Effects of Piperine on Testicular Development: Stimulating Leydig Cell Development but Inhibiting Spermatogenesis in Rats

Chen, X., Ge, F., Liu, J., Bao, S., Chen, Y., Li, D., Li, Y., Huang, T., Chen, X., Zhu, Q., et al. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00244 · Cited by 36

Soluplus ® /TPGS mixed micelles for co-delivery of docetaxel and piperine for combination cancer therapy

Ding, Y., Ding, Y., Wang, Y., Wang, C., Gao, M., Xu, Y., Ma, X., Wu, J., & Li, L. (2019) · Pharmaceutical Development and Technology · doi:10.1080/10837450.2019.1679834 · Cited by 36

Piperine as a neuroprotective functional component in rats with cerebral ischemic injury

Hua, S., Liu, J., Zhang, Y., Li, J., Zhang, X., Dong, L., Zhao, Y., & Fu, X. (2019) · Food Science & Nutrition · doi:10.1002/fsn3.1185 · Cited by 35

Inhibition of Bacteroidetes and Firmicutes by select phytochemicals

Lakes, J. E., Richards, C. I., & Flythe, M. D. D. (2019) · Anaerobe · doi:10.1016/j.anaerobe.2019.102145 · Cited by 35

Piperine mitigates behavioral impairments and provides neuroprotection against 3-nitropropinoic acid-induced Huntington disease-like symptoms

Salman, M., Tabassum, H., & Parvez, S. (2020) · Nutritional Neuroscience · doi:10.1080/1028415x.2020.1721645 · Cited by 35

Protective effects of piperine against copper-ascorbate induced toxic injury to goat cardiac mitochondria in vitro

Dutta, M., Ghosh, A. K., Mishra, P., Jain, G., Rangari, V. D., Chattopadhyay, A., Das, T., Bhowmick, D., & Bandyopadhyay, D. (2014) · Food & Function · doi:10.1039/c4fo00355a · Cited by 34

Antioxidative Effects of Piperine against Cadmium-Induced Oxidative Stress in Cultured Human Peripheral Blood Lymphocytes

Verma, N., Bal, S., Gupta, R., Aggarwal, N. K., & Yadav, A. (2018) · Journal of Dietary Supplements · doi:10.1080/19390211.2018.1481485 · Cited by 34

Delivery of Apoptosis-inducing Piperine to Triple-negative Breast Cancer Cells via Co-polymeric Nanoparticles

Rad, J. G., & Hoskin, D. W. (2020) · Anticancer Research · doi:10.21873/anticanres.13998 · Cited by 34

Comparative efficacy of piperine, curcumin and picroliv against Cd immunotoxicity in mice

Pathak, N., & Khandelwal, S. (2008) · BioMetals · doi:10.1007/s10534-008-9150-y · Cited by 33

Influence of piperine and quercetin on antidiabetic potential of curcumin

Kaur, G., Invally, M., & Chintamaneni, M. (2016) · Journal of Complementary and Integrative Medicine · doi:10.1515/jcim-2016-0016 · Cited by 33

Piperine Inhibits Platelet-Derived Growth Factor-BB-Induced Proliferation and Migration in Vascular Smooth Muscle Cells

Lee, K. P., Lee, K., Park, W., Kim, H., & Hong, H. (2014) · Journal of Medicinal Food · doi:10.1089/jmf.2014.3229 · Cited by 31

Comparative Phytochemical Evaluation and Antioxidant Assay ofPiper longumL. andPiper chabaHunter Used in Indian Traditional Systems of Medicine

Rameshkumar, K. B., Aravind, A., & Mathew, P. J. (2011) · Journal of Herbs Spices & Medicinal Plants · doi:10.1080/10496475.2011.632116 · Cited by 31

The effect of piperine on midazolam plasma concentration in healthy volunteers, a research on the CYP3A-involving metabolism

Rezaee, M. M., Kazemi, S., Kazemi, M. T., Gharooee, S., Yazdani, E., Gharooee, H., Shiran, M. R., & Moghadamnia, A. A. (2014) · DARU Journal of Pharmaceutical Sciences · doi:10.1186/2008-2231-22-8 · Cited by 31

Combinatorial therapeutic effect of resveratrol and piperine on murine model of systemic lupus erythematosus

Pannu, N., & Bhatnagar, A. (2019) · Inflammopharmacology · doi:10.1007/s10787-019-00662-w · Cited by 31

Th1-Biased Immunomodulation and In Vivo Antitumor Effect of a Novel Piperine Analogue

Santos, J. A. F., Brito, M. T., Ferreira, R. C., Moura, A. P. G., de Sousa, T. K. G., Batista, T. M., Mangueira, V. M., Leite, F. C., da Cruz, R. M. D., Vieira, G. C., et al. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19092594 · Cited by 30

Piperine Suppresses the Expression of CXCL8 in Lipopolysaccharide-Activated SW480 and HT-29 Cells via Downregulating the Mitogen-Activated Protein Kinase Pathways

Hou, X.-F., Pan, H., Xu, L., Zha, Q., He, X., & Ouyang, D. (2014) · Inflammation · doi:10.1007/s10753-014-0075-z · Cited by 29

Natural based piperine derivatives as potent monoamine oxidase inhibitors: an in silico ADMET analysis and molecular docking studies

Dhiman, P., Malik, N., & Khatkar, A. (2020) · BMC Chemistry · doi:10.1186/s13065-020-0661-0 · Cited by 29

Piperine, active substance of black pepper, alleviates hypertension induced by NO synthase inhibition

Hlavačková, L., Urbanová, A., Uličná, O., Janega, P., Cerna, A., & Babál, P. (2010) · Bratislavské lekárske listy/Bratislava medical journal · doi:10.1007/bf03657315 · Cited by 28

Piperine blocks interleukin-2-driven cell cycle progression in CTLL-2 T lymphocytes by inhibiting multiple signal transduction pathways

Doucette, C. D., Greenshields, A. L., Liwski, R., & Hoskin, D. W. (2015) · Toxicology Letters · doi:10.1016/j.toxlet.2015.01.020 · Cited by 28

Effect of Piperine on the Pharmacokinetics and Pharmacodynamics of Glimepiride in Normal and Streptozotocin - Induced Diabetic Rats

Veeresham, C., Samala, S., & Rani, T. S. (2012) · Natural Product Communications · doi:10.1177/1934578x1200701009 · Cited by 27

The inhibitory effect of piperine from Fructus piperis extract on the degranulation of RBL-2H3 cells

Jing, H., Zhang, T., Han, S., Cao, J., Chen, Q., & Wang, S. (2014) · Fitoterapia · doi:10.1016/j.fitote.2014.10.001 · Cited by 27

Modulatory Effects of Curcumin in Conjunction with Piperine on Benzo(A)Pyrene-Mediated DNA Adducts and Biotransformation Enzymes

Sehgal, A. K., Kumar, M., Jain, M., & Dhawan, D. K. (2013) · Nutrition and Cancer · doi:10.1080/01635581.2013.805421 · Cited by 26

Scientific Opinion on Flavouring Group Evaluation 86, Revision 2 (FGE.86Rev2): Consideration of aliphatic and arylalkyl amines and amides evaluated by JECFA (65th meeting)

EFSA Panel on Food Contact Materials, E. (2015) · EFSA Journal · doi:10.2903/j.efsa.2015.3998 · Cited by 26

Combination Therapy with Curcumin Alone Plus Piperine Ameliorates Ovalbumin-Induced Chronic Asthma in Mice

Chauhan, P., Jaiswal, A., Subhashini, & Singh, R. (2018) · Inflammation · doi:10.1007/s10753-018-0836-1 · Cited by 24

Promising Antituberculosis Activity of Piperine Combined with Antimicrobials: A Systematic Review

Hegeto, L. A., Caleffi-Ferracioli, K. R., de Souza, J. V. P., de Almeida, A. L., de Vasconcelos, S. S. N., Barros, I. L. E., Canezin, P. H., Campanerut‐Sá, P. A. Z., Scodro, R. B. D. L., Siqueira, V. L. D., et al. (2018) · Microbial Drug Resistance · doi:10.1089/mdr.2018.0107 · Cited by 24

Piperine derivatives as potential inhibitors of Survivin: An in silico molecular docking

Sattarinezhad, E., Bordbar, A., & Fani, N. (2015) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2015.05.016 · Cited by 23

Effect of Piperine on Antihyperglycemic Activity and Pharmacokinetic Profile of Nateglinide

Sama, V., Nadipelli, M., Yenumula, P., Bommineni, M. R., & Mullangi, R. (2012) · Arzneimittelforschung · doi:10.1055/s-0032-1314849 · Cited by 22

Molecular Signatures of Humic Acids from Different Sources as Revealed by Ultrahigh Resolution Mass Spectrometry

Qin, S., Xu, C., Xu, Y., Bai, Y., & Guo, F. (2020) · Journal of Chemistry · doi:10.1155/2020/7171582 · Cited by 22

Hepatoprotective effects of red beetroot‐based beverages against CCl4‐induced hepatic stress inSprague Dawleyrats

Ul‐Haq, I., Butt, M. S., Randhawa, M. A., & Shahid, M. (2019) · Journal of Food Biochemistry · doi:10.1111/jfbc.13057 · Cited by 21

Synthesis and Biological Activity of Piperine Derivatives as Potential PPARγ Agonists

Wang, Y., Yao, Y., Liu, J., Wu, L., Liu, T., Cui, J., & Lee, D. Y. W. (2020) · Drug Design Development and Therapy · doi:10.2147/dddt.s238245 · Cited by 21

Piper guineense(Piperaceae): Chemistry, Traditional Uses, and Functional Properties of West African Black Pepper

Juliani, H. R., Koroch, A. R., Giordano, L., Amekuse, L. S., Koffa, S., Asante-Dartey, J., & Simon, J. E. (2013) · ACS symposium series · doi:10.1021/bk-2013-1127.ch003 · Cited by 19

Piperine treatment suppresses Helicobacter pylori toxin entry in to gastric epithelium and minimizes β-catenin mediated oncogenesis and IL-8 secretion in vitro.

Tharmalingam, N., Park, M., Lee, M. H., Woo, H. J., Kim, H. W., Yang, J. Y., Rhee, K.-J., & Kim, J. B. (2016) · PubMed · Cited by 18

Histamine Release Inhibitory Activity of Piper nigrum Leaf

Hirata, N., Naruto, S., Inaba, K., Itoh, K., Tokunaga, M., Iinuma, M., & Matsuda, H. (2008) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.31.1973 · Cited by 17

Protective effect of piperine on electrophysiology abnormalities of left atrial myocytes induced by hydrogen peroxide in rabbits

Liu, Y., Zhang, Y., Lin, K., Zhang, D., Tian, M., Guo, H., Wang, Y., Li, Y., & Shan, Z. (2013) · Life Sciences · doi:10.1016/j.lfs.2013.10.024 · Cited by 17

Piperine Congeners as Inhibitors of Vascular Smooth Muscle Cell Proliferation

Mair, C. E., Liu, R., Atanasov, A. G., Wimmer, L., Nemetz-Fiedler, D., Sider, N., Heiß, E. H., Mihovilovič, M. D., Dirsch, V. M., & Rollinger, J. M. (2015) · Planta Medica · doi:10.1055/s-0035-1546165 · Cited by 17

Effect of Piperine on Liver Function of CF-1 albino Mice

Peela, J. R., Kolla, S., Elshaari, F. A., Elshaari, F., Elawamy, H., Elfrady, M., Singh, R., Belkhier, A., Srikumar, S., Said, A. N. A., et al. (2015) · Infectious Disorders - Drug Targets · doi:10.2174/1871526515666150724114616 · Cited by 16

Comparative Physicochemical Evaluation of Fruits and Anti depressant Potential of volatile oils of fruits of Local Piper Species

Khan, M. (2015) · Oriental Journal Of Chemistry · doi:10.13005/ojc/310167 · Cited by 15

Reversible Anti-Spermatogenic Effect of Piperine on Epididymis and Seminal Vesicles of Albino Rats

Chinta, G., & Periyasamy, L. (2016) · Drug Research · doi:10.1055/s-0042-108186 · Cited by 15

Scientific Opinion on Flavouring Group Evaluation 86, Revision 1 (FGE.86Rev1): Consideration of aliphatic and aromatic amines and amides evaluated by JECFA (65th meeting)

EFSA Panel on Food Contact Materials, E. (2011) · EFSA Journal · doi:10.2903/j.efsa.2011.1926 · Cited by 14

Autophagy-Regulating N-Heterocycles Derivatives as Potential Anticancer Agents

Liang, X., Zhang, L., Li, F., Luan, S., He, C., Yin, L., Yin, Z., Zou, Y., Yue, G., Li, L., et al. (2019) · Future Medicinal Chemistry · doi:10.4155/fmc-2019-0294 · Cited by 14

Piperine inhibits type II phosphatidylinositol 4-kinases: a key component in phosphoinositides turnover

Bojjireddy, N., Sinha, R. K., & Subrahmanyam, G. (2014) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-014-2041-3 · Cited by 12

Synthesis, Radical-Scavenging Activities, and Protective Effects against AAPH-Induced Oxidative Damage in DNA and Erythrocytes of Piperine Derivatives

Qin, B., Yang, K., & Cao, R. (2020) · Journal of Chemistry · doi:10.1155/2020/9026286 · Cited by 12

Facilitatory effect of Piperine on the Anticonvulsant effect of Sodium valproate against Pentylenetetrazole induced Seizures in mice

Surendran, S., Babu, M., Joseph, J., & Padma, U. D. (2020) · Research Journal of Pharmacy and Technology · doi:10.5958/0974-360x.2020.00124.9 · Cited by 10

Caregiving for Older Adults with Obesity in the United States

Ankuda, C. K., Harris, J. A., Ornstein, K. A., Levine, D. A., Langa, K. M., & Kelley, A. S. (2017) · Journal of the American Geriatrics Society · doi:10.1111/jgs.14918 · Cited by 8

Combination Therapy of Piperine and Phenytoin in Maximal Electroshock Induced Seizures in Mice: Isobolographic and Biochemical Analysis

Saraogi, P., Vohora, D., Khanam, R., & Pillai, K. (2013) · Drug Research · doi:10.1055/s-0033-1337940 · Cited by 6

[Piperine inhibits the transformation of endothelial cells into fibroblasts].

Li, Y. P., Gao, L., Shi, H., Feng, S., Tian, X., Kong, L. Y., & Zhang, Y. Z. (2019) · PubMed · doi:10.3760/cma.j.issn.0253-3758.2019.07.009 · Cited by 6

Anticancer activity of curcumin alone and in combination with piperine in Dalton lymphoma ascites bearing mice

(2020) · Indian Journal of Experimental Biology · doi:10.56042/ijeb.v58i03.65443 · Cited by 6

Evaluation of Piperine Content from Roots of Piper Longum Linn., Originated from Different Sources with Comparison of Zonal Variation in Odisha, India

Mohapatra, M., & Basak, U. C. (2015) · International journal of pharma research and review · Cited by 5

[Effect of piperine on 5-HT and synaptophysin expression of rats with irritable bowel syndrome].

Wu, S.-J., Wang, R.-Y., Xue, J.-X., & Pan, J. (2013) · PubMed · Cited by 4

PROTECTIVE EFFECTS OF PIPERINE ON CYPERMETHRININDUCED HAEMATOLOGICAL TOXICITY IN RATS

Sankar, P., & Ramya, K. (2017) · Cited by 1

Molecular and pharmacological aspects of piperine as a potential molecule for disease prevention and management: evidence from clinical trials

Tripathi, A. K., Ray, A. K., & Mishra, S. K. (2022) · Beni-Suef University Journal of Basic and Applied Sciences · doi:10.1186/s43088-022-00196-1 · Cited by 246

Moroccan medicinal plants traditionally used for the treatment of skin diseases: From ethnobotany to clinical trials

Ajjoun, M., Kharchoufa, L., Merrouni, I. A., & Elachouri, M. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.115532 · Cited by 198

Curcumin‐piperine co‐supplementation and human health: A comprehensive review of preclinical and clinical studies

Heidari, H., Bagherniya, M., Majeed, M. A., Sathyapalan, T., Jamialahmadi, T., & Sahebkar, A. (2023) · Phytotherapy Research · doi:10.1002/ptr.7737 · Cited by 195

Piperidine Derivatives: Recent Advances in Synthesis and Pharmacological Applications

Frolov, N. A., & Vereshchagin, A. N. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032937 · Cited by 192

Nanotechnology: A novel tool to enhance the bioavailability of micronutrients

Arshad, R., Gulshad, L., Ul‐Haq, I., Farooq, M. A., AL-Farga, A. M., Siddique, R., Manzoor, M. F., & Karrar, E. M. A. (2021) · Food Science & Nutrition · doi:10.1002/fsn3.2311 · Cited by 181

A Review on Therapeutic Potential of Piper nigrum L. (Black Pepper): The King of Spices

Damanhouri, Z. A. (2014) · Medicinal & Aromatic Plants · doi:10.4172/2167-0412.1000161 · Cited by 257

Black Pepper (Piper nigrum L.): The King of Spices

Soni, P., Soni, V., & Choudhary, N. K. (2020) · Science of spices & herbs · doi:10.2174/9789811468360120030008 · Cited by 1

Therapeutic Role of Piper nigrum L (Black Pepper) and Pharmacological Activities

Saleem, A., Naureen, I., Naeem, M., Tasleem, G., Ahmed, H., & Farooq, U. (2022) · Scholars International Journal of Biochemistry · doi:10.36348/sijb.2022.v05i01.003 · Cited by 41

Therapeutic Potential of Piperine: A Review

Sarkar, S., Sarkar, S., Sanjib, G., Mistry, J., & Biswas, M. (2023) · International Journal of Zoological Investigations · doi:10.33745/ijzi.2023.v09i02.020

Therapeutic Potential of Piperine: A Comprehensive Review

Singh, S. K., & Shukla, A. (2023) · The Natural Products Journal · doi:10.2174/0122103155273860230928071249 · Cited by 6