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Cited by 1,444

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Overall C as a measure of discrimination in survival analysis: model specific population value and confidence interval estimation

Pencina, Michael J., D'Agostino, Ralph B.·2004·Statistics in Medicine
DOI 10.1002/sim.1802
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Abstract

The assessment of the discrimination ability of a survival analysis model is a problem of considerable theoretical interest and important practical applications. This issue is, however, more complex than evaluating the performance of a linear or logistic regression. Several different measures have been proposed in the biostatistical literature. In this paper we investigate the properties of the overall C index introduced by Harrell as a natural extension of the ROC curve area to survival analysis. We develop the overall C index as a parameter describing the performance of a given model applied to the population under consideration and discuss the statistic used as its sample estimate. We discover a relationship between the overall C and the modified Kendall's τand construct a confidence interval for our measure based on the asymptotic normality of its estimate. Then we investigate via simulations the length and coverage probability of this interval. Finally, we present a real life example evaluating the performance of a Framingham Heart Study model. Copyright © 2004 John Wiley & Sons, Ltd.

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Research works printed but not linked: 15

  1. D'Agostino RB, 1997, Proceedings of the Biometrics Section, 253
  2. 10.1002/(SICI)1097-0258(19960229)15:4<361::AID-SIM168>3.0.CO;2-4 · DOI
  3. 10.1016/0022-2496(75)90001-2 · DOI · Paper page
  4. Nam BH, 2002, Discrimination Index, the Area Under the ROC Curve; in Goodness‐of‐Fit Tests and Model Validity
  5. 10.1002/sim.4780090503 · DOI
  6. 10.1093/biomet/77.1.216 · DOI
  7. 10.1002/sim.4780122413 · DOI
  8. 10.1093/biomet/75.3.525 · DOI
  9. Noether GE, 1967, Elements of Nonparametric Statistics
  10. 10.1148/radiology.143.1.7063747 · DOI · Paper page
  11. Kendall MG, 1970, Rank Correlation Methods
  12. 10.1007/978-1-4899-2819-1 · DOI
  13. Feller W, 1968, An Introduction to Probability Theory
  14. 10.1007/978-1-4612-9995-0 · DOI
  15. Lehmann EL, 1975, Nonparametrics

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Metadata

Authors
Pencina, M. J., & D'Agostino, R. B.
Venue
Statistics in Medicine
Publisher
Wiley
Published
2004-06-14
Volume
23
Issue
13
Pages
2109-2123
ISSN
  • 0277-6715 (ISSN-L)
  • 1097-0258
DOI
10.1002/sim.1802
OpenAlex
W2149407433
Cited by
1,444
References
2
FWCI
10.50
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)

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CoChat. (2026). Citation check: Overall C as a measure of discrimination in survival analysis: model specific population value and confidence interval estimation. https://app.cochat.ai/papers/10.1002/sim.1802
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Pencina, M. J., & D'Agostino, R. B. (2004). Overall C as a measure of discrimination in survival analysis: model specific population value and confidence interval estimation. Statistics in Medicine. https://doi.org/10.1002/sim.1802

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