The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Test statistics and sample size formulae for comparative binomial trials with null hypothesis of non‐zero risk difference or non‐unity relative risk
Abstract
When it is required to establish a materially significant difference between two treatments, or, alternatively, to show that two treatments are equivalent, standard test statistics and sample size formulae based on a null hypothesis of no difference no longer apply. This paper reviews some of the test statistics and sample size formulae proposed for comparative binomial trials when the null hypothesis is of a specified non‐zero difference or non‐unity relative risk. Methods based on restricted maximum likelihood estimation are recommended and applied to studies of pertussis vaccine.
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Oral Apixaban for the Treatment of Acute Venous Thromboembolism
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Metadata
- Authors
- Farrington, C. P., & Manning, G.
- Venue
- Statistics in Medicine
- Publisher
- Wiley
- Published
- 1990-12
- Volume
- 9
- Issue
- 12
- Pages
- 1447-1454
- ISSN
- 0277-6715 (ISSN-L)
- 1097-0258
- OpenAlex
- W2099207046
- Cited by
- 657
- References
- 13
- FWCI
- 1.70
- Type
- journal article
- Language
- en
- Open access
- closed
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