Cited by 160Reproductive Health and TechnologiesOvarian function and disordersReproductive Health and Contraception

Using the ratio of urinary oestrogen and progesterone metabolites to estimate day of ovulation

Baird, Donna Day, Weinberg, Clarice R., Wilcox, Allen J., McConnaughey, D. Robert, Musey, Paul I.·1991·Statistics in Medicine

Abstract

We have developed a method of estimating day of ovulation using urinary ovarian hormone data. The method identifies a day of luteal transition that occurs at the shift from production of follicular oestrogen to luteal progesterone. The algorithm for identifying this shift was evaluated and judged better than specified alternatives in that it resulted in (1) a high concordance between the day of luteal transition and peaks in urinary luteinizing hormone (LH) for cycles with well‐defined peaks, (2) a low variance in the length of the luteal phase of the menstrual cycle, which presumably reflects a low measurement error in estimating day of ovulation, and (3) a high proportion of cycles for which an approximate day of ovulation could be determined. To validate the new algorithm, it was applied to an independent data set. The algorithm identified a day of luteal transition in 88 percent of these cycles, and the identified day occurred within two days of the urinary LH peak for all of the cycles with clear LH peaks. Determination of the day of luteal transition to estimate ovulation requires only first‐morning urine specimens, requires no correction for day‐to‐day variations in urine concentration, and can be applied to a mid‐ycle window of data.

Integrity signals

Registry

Crossref · 10.1002/sim.4780100209

Cites

22 of 22 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

2 of the 24 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Authors
Baird, D. D., Weinberg, C. R., Wilcox, A. J., McConnaughey, D. R., & Musey, P. I.
Affiliations
  • National Institutes of Health (US)
  • Clark Atlanta University (US)
Venue
Statistics in Medicine
Publisher
Wiley
Published
1991-02
Volume
10
Issue
2
Pages
255-266
ISSN
  • 0277-6715 (ISSN-L)
  • 1097-0258
OpenAlex
W2168906967
Cited by
160
References
24
Citations by year
2026: 2 · 2024: 2 · 2023: 3 · 2022: 3 · 2021: 1 · 2020: 6 · 2019: 6 · 2018: 9 · 2017: 4 · 2016: 5 · 2015: 8 · 2014: 7 · 2013: 2 · 2012: 4
FWCI
3.62
Type
journal article
Language
en
Open access
closed
Locations
  • Statistics in Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
  • Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Health and Contraception
Keywords
luteal progesterone, luteinizing hormone peak, luteal phase length, menstrual cycle, ovarian hormones, first morning urine
MeSH terms
Algorithms, Estrogens, Female, Humans, Luteinizing Hormone, Ovulation Detection, Progesterone

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review