The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Dendrimer‐Entrapped Gold Nanoparticles as a Platform for Cancer‐Cell Targeting and Imaging
Open accessAbstract
We present a general approach for the targeting and imaging of cancer cells using dendrimer‐entrapped gold nanoparticles (Au DENPs). Au DENPs were found to be able to covalently link with targeting and imaging ligands for subsequent cancer‐cell targeting and imaging. The Au DENPs linked with defined numbers of folic acid (FA) and fluorescein isothiocyanate (FI) molecules are water soluble, stable, and biocompatible. In vitro studies show that the FA‐ and FI‐modified Au DENPs can specifically bind to KB cells (a human epithelial carcinoma cell line) that overexpress high‐affinity folate receptors and they are internalized dominantly into lysosomes of target cells within 2 h. These findings demonstrate that Au DENPs may serve as a general platform for cancer imaging and therapeutics.
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Targeting nanoparticles to cancer
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Applications of gold nanoparticles in cancer nanotechnology
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Size-Dependent Photothermal Conversion Efficiencies of Plasmonically Heated Gold Nanoparticles
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Gold, Silver, and Palladium Nanoparticles: A Chemical Tool for Biomedical Applications
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Metadata
- Authors
- Shi, X., Wang, S., Meshinchi, S., Van Antwerp, M. E., Bi, X., Lee, I., & Baker, J. R.
- Venue
- Small
- Publisher
- Wiley
- Published
- 2007-06-22
- Volume
- 3
- Issue
- 7
- Pages
- 1245-1252
- ISSN
- 1613-6810 (ISSN-L)
- 1613-6829
- OpenAlex
- W1987619840
- Cited by
- 318
- References
- 24
- FWCI
- 23.29
- Type
- journal article
- Language
- en
- Open access
- green
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