The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Inhibition of Influenza Virus Infection by Multivalent Sialic‐Acid‐Functionalized Gold Nanoparticles
Abstract
An efficient synthesis of sialic‐acid‐terminated glycerol dendron to chemically functionalize 2 nm and 14 nm gold nanoparticles (AuNPs) is described. These nanoparticles are highly stable and show high activity towards the inhibition of influenza virus infection. As the binding of the viral fusion protein hemagglutinin to the host cell surface is mediated by sialic acid receptors, a multivalent interaction with sialic‐acid‐functionalized AuNPs is expected to competitively inhibit viral infection. Electron microscopy techniques and biochemical analysis show a high binding affinity of the 14 nm AuNPs to hemagglutinin on the virus surface and, less efficiently, to isolated hemagglutinin. The functionalized AuNPs are nontoxic to the cells under the conditions studied. This approach allows a new type of molecular‐imaging activity‐correlation and is of particular relevance for further application in alternative antiviral therapy.
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Daniel, M.-C., & Astruc, D. (2004) · Chemical Reviews · doi:10.1021/cr030698+ · Cited by 12,446
Nanoparticles with Raman Spectroscopic Fingerprints for DNA and RNA Detection
Cao, Y. C., Jin, R., & Mirkin, C. A. (2002) · Science · doi:10.1126/science.297.5586.1536 · Cited by 2,971
Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity
Boisselier, E., & Astruc, D. (2009) · Chemical Society Reviews · doi:10.1039/b806051g · Cited by 2,842
Lewinski, N., Colvin, V., & Drezek, R. (2008) · Small · doi:10.1002/smll.200700595 · Cited by 2,810
Receptor Binding and Membrane Fusion in Virus Entry: The Influenza Hemagglutinin
Skehel, J. J., & Wiley, D. C. (2000) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.69.1.531 · Cited by 2,706
Gold Nanoparticles in Biology: Beyond Toxicity to Cellular Imaging
Murphy, C. J., Gole, A. M., Stone, J. W., Sisco, P. N., Alkilany, A. M., Goldsmith, E. C., & Baxter, S. C. (2008) · Accounts of Chemical Research · doi:10.1021/ar800035u · Cited by 1,807
Biological applications of gold nanoparticles
Sperling, R. A., Rivera Gil, P., Zhang, F., Zanella, M., & Parak, W. J. (2008) · Chemical Society Reviews · doi:10.1039/b712170a · Cited by 1,799
Tailoring Surface Plasmons through the Morphology and Assembly of Metal Nanoparticles
Liz-Marzán, L. M. (2006) · Langmuir · doi:10.1021/la0513353 · Cited by 1,645
Fluorescence Quenching of Dye Molecules near Gold Nanoparticles: Radiative and Nonradiative Effects
Dulkeith, E., Morteani, A. C., Niedereichholz, T., Klar, T. A., Feldmann, J., Levi, S. A., van Veggel, F. C. J. M., Reinhoudt, D. N., Möller, M., & Gittins, D. I. (2002) · Physical Review Letters · doi:10.1103/physrevlett.89.203002 · Cited by 1,283
Rational and Combinatorial Design of Peptide Capping Ligands for Gold Nanoparticles
Lévy, R., Thanh, N. T. K., Doty, R. C., Hussain, I., Nichols, R. J., Schiffrin, D. J., Brust, M., & Fernig, D. G. (2004) · Journal of the American Chemical Society · doi:10.1021/ja0487269 · Cited by 724
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Silver Nanoparticles as Potential Antiviral Agents
Galdiero, S., Falanga, A., Vitiello, M., Cantisani, M., Marra, V., & Galdiero, M. (2011) · Molecules · doi:10.3390/molecules16108894 · Cited by 963
Intrinsic therapeutic applications of noble metal nanoparticles: past, present and future
Arvizo, R. R., Bhattacharyya, S., Kudgus, R. A., Giri, K., Bhattacharya, R., & Mukherjee, P. (2012) · Chemical Society Reviews · doi:10.1039/c2cs15355f · Cited by 866
Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic
Weiss, C., Carriere, M., Fusco, L., Capua, I., Regla-Nava, J. A., Pasquali, M., Scott, J. A., Vitale, F., Unal, M. A., Mattevi, C., et al. (2020) · ACS Nano · doi:10.1021/acsnano.0c03697 · Cited by 601
Cheng, C., Li, S., Thomas, A., Kotov, N. A., & Haag, R. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.6b00520 · Cited by 527
Self-citationElbeshehy, E. K. F., Elazzazy, A. M., & Aggelis, G. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00453 · Cited by 383
Metadata
- Authors
- Papp, I., Sieben, C., Ludwig, K., Roskamp, M., Böttcher, C., Schlecht, S., Herrmann, A., & Haag, R.
- Venue
- Small
- Publisher
- Wiley
- Published
- 2010-11-22
- Volume
- 6
- Issue
- 24
- Pages
- 2900-2906
- ISSN
- 1613-6810 (ISSN-L)
- 1613-6829
- OpenAlex
- W2151671351
- Cited by
- 313
- References
- 31
- FWCI
- 5.45
- Type
- journal article
- Language
- en
- Open access
- closed
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- Papp, I., Sieben, C., Ludwig, K., Roskamp, M., Böttcher, C., Schlecht, S., Herrmann, A., & Haag, R. (2010). Inhibition of Influenza Virus Infection by Multivalent Sialic‐Acid‐Functionalized Gold Nanoparticles. Small. https://doi.org/10.1002/smll.201001349
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