The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Cytotoxicity of Nanoparticles
Abstract
Human exposure to nanoparticles is inevitable as nanoparticles become more widely used and, as a result, nanotoxicology research is now gaining attention. However, while the number of nanoparticle types and applications continues to increase, studies to characterize their effects after exposure and to address their potential toxicity are few in comparison. In the medical field in particular, nanoparticles are being utilized in diagnostic and therapeutic tools to better understand, detect, and treat human diseases. Exposure to nanoparticles for medical purposes involves intentional contact or administration; therefore, understanding the properties of nanoparticles and their effect on the body is crucial before clinical use can occur. This Review presents a summary of the in vitro cytotoxicity data currently available on three classes of nanoparticles. With each of these nanoparticles, different data has been published about their cytotoxicity due to varying experimental conditions as well as differing nanoparticle physiochemical properties. For nanoparticles to move into the clinical arena, it is important that nanotoxicology research uncovers and understands how these multiple factors influence the toxicity of nanoparticles so that their undesirable properties can be avoided.
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“Compared with viruses, nanoparticles have lower immunogenicity, longer circulation times, and fewer adverse events.403”
From p53: from understanding its structure to advances in therapeutic targeting (2026) · doi:10.1038/s41392-025-02549-5 · cites this paper as [403]
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Cites
Brunner, T. J., Wick, P., Manser, P., Spohn, P., Grass, R. N., Limbach, L. K., Bruinink, A., & Stark, W. J. (2006) · Environmental Science & Technology · doi:10.1021/es052069i · Cited by 1,385
Oops they did it again! Carbon nanotubes hoax scientists in viability assays
Wörle-Knirsch, J. M., Pulskamp, K., & Krug, H. F. (2006) · Nano Letters · doi:10.1021/nl060177c · Cited by 994
On the Cyto‐Toxicity Caused by Quantum Dots
Shiohara, A., Hoshino, A., Hanaki, K., Suzuki, K., & Yamamoto, K. (2004) · Microbiology and Immunology · doi:10.1111/j.1348-0421.2004.tb03478.x · Cited by 385
Ryman-Rasmussen, J. P., Riviere, J. E., & Monteiro-Riviere, N. A. (2007) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700508 · Cited by 357
Cited by
Banerjee, I., Pangule, R. C., & Kane, R. S. (2011) · Advanced Materials · doi:10.1002/adma.201001215 · Cited by 2,749
Sharifi, S., Behzadi, S., Laurent, S., Laird Forrest, M., Stroeve, P., & Mahmoudi, M. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15188f · Cited by 1,460
Silver nanoparticles induce cytotoxicity by a Trojan-horse type mechanism
Park, E.-J., Yi, J., Kim, Y., Choi, K., & Park, K. (2010) · Toxicology in Vitro · doi:10.1016/j.tiv.2009.12.001 · Cited by 746
Zha, Z., Yue, X., Ren, Q., & Dai, Z. (2013) · Advanced Materials · doi:10.1002/adma.201202211 · Cited by 746
Golden carbon nanotubes as multimodal photoacoustic and photothermal high-contrast molecular agents
Kim, J.-W., Galanzha, E. I., Shashkov, E. V., Moon, H.-M., & Zharov, V. P. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.231 · Cited by 710
Metadata
- Authors
- Lewinski, N., Colvin, V., & Drezek, R.
- Venue
- Small
- Publisher
- Wiley
- Published
- 2008-01-11
- Volume
- 4
- Issue
- 1
- Pages
- 26-49
- ISSN
- 1613-6810 (ISSN-L)
- 1613-6829
- OpenAlex
- W2137374477
- Cited by
- 2,810
- References
- 4
- FWCI
- 68.92
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
