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Boron Nitride Nanotubes: Biocompatibility and Potential Spill‐Over in Nanomedicine
Open accessAbstract
Boron nitride nanotubes (BNNTs) represent an innovative and extremely intriguing class of nanomaterials. Thanks to their special chemical and physical characteristics, they have already found a large number of applications in the field of nanotechnology, and recent studies have shown their possible exploitation in the biomedical domain, both as nanocarriers and, more interestingly, as nanotransducers. In this review, the latest findings on the interactions between BNNTs and living systems are summarized, starting with the major issues of their stabilization in physiological media and their functionalization with bioactive molecules. Thereafter the biocompatibility data which have so far been made available are discussed, and the need for further extensive and standardized tests is highlighted. Finally, the appealing diagnostic and therapeutic opportunities offered by BNNT‐based systems are described, envisioning the potential spill‐over effects of such 'smart' and 'active' nanoparticles in nanomedicine.
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Cites
Noncovalent sidewall functionalization of single-walled carbon nanotubes for protein immobilization
Chen, R. J., Zhang, Y., Wang, D., & Dai, H. (2001) · Journal of the American Chemical Society · doi:10.1021/ja010172b · Cited by 2,534
Oops they did it again! Carbon nanotubes hoax scientists in viability assays
Wörle-Knirsch, J. M., Pulskamp, K., & Krug, H. F. (2006) · Nano Letters · doi:10.1021/nl060177c · Cited by 994
Cited by
Highly Water-Soluble, Porous, and Biocompatible Boron Nitrides for Anticancer Drug Delivery
Weng, Q., Wang, B., Wang, X., Hanagata, N., Li, X., Liu, D., Wang, X., Jiang, X., Bando, Y., & Golberg, D. (2014) · ACS Nano · doi:10.1021/nn5014808 · Cited by 455
Metadata
- Authors
- Ciofani, G., Danti, S., Genchi, G. G., Mazzolai, B., & Mattoli, V.
- Venue
- Small
- Publisher
- Wiley
- Published
- 2013-02-19
- Volume
- 9
- Issue
- 9-10
- Pages
- 1672-1685
- ISSN
- 1613-6810 (ISSN-L)
- 1613-6829
- OpenAlex
- W2132752213
- Cited by
- 218
- References
- 2
- FWCI
- 8.58
- Type
- journal article
- Language
- en
- Open access
- green
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- Ciofani, G., Danti, S., Genchi, G. G., Mazzolai, B., & Mattoli, V. (2013). Boron Nitride Nanotubes: Biocompatibility and Potential Spill‐Over in Nanomedicine. Small. https://doi.org/10.1002/smll.201201315
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