The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Highly Water-Soluble, Porous, and Biocompatible Boron Nitrides for Anticancer Drug Delivery
Abstract
Developing materials for "Nano-vehicles" with clinically approved drugs encapsulated is envisaged to enhance drug therapeutic effects and reduce the adverse effects. However, design and preparation of the biomaterials that are porous, nontoxic, soluble, and stable in physiological solutions and could be easily functionalized for effective drug deliveries are still challenging. Here, we report an original and simple thermal substitution method to fabricate perfectly water-soluble and porous boron nitride (BN) materials featuring unprecedentedly high hydroxylation degrees. These hydroxylated BNs are biocompatible and can effectively load anticancer drugs (e.g., doxorubicin, DOX) up to contents three times exceeding their own weight. The same or even fewer drugs that are loaded on such BN carriers exhibit much higher potency for reducing the viability of LNCaP cancer cells than free drugs.
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Cites
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Metal–Organic Frameworks in Biomedicine
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Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives
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Mesoporous Materials for Drug Delivery
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Boron Nitride Nanotubes and Nanosheets
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Cited by
Construction of 3D Skeleton for Polymer Composites Achieving a High Thermal Conductivity
Yao, Y., Sun, J., Zeng, X., Sun, R., Xu, J., & Wong, C. (2018) · Small · doi:10.1002/smll.201704044 · Cited by 389
Boron nitride nanomaterials: biocompatibility and bio-applications
Merlo, A., Mokkapati, V. R. S. S., Pandit, S., & Mijakovic, I. (2018) · Biomaterials Science · doi:10.1039/c8bm00516h · Cited by 282
Metadata
- Authors
- Weng, Q., Wang, B., Wang, X., Hanagata, N., Li, X., Liu, D., Wang, X., Jiang, X., Bando, Y., & Golberg, D.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2014-05-07
- Volume
- 8
- Issue
- 6
- Pages
- 6123-6130
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W2329440736
- Cited by
- 455
- References
- 33
- FWCI
- 12.66
- Type
- journal article
- Language
- en
- Open access
- closed
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- Weng, Q., Wang, B., Wang, X., Hanagata, N., Li, X., Liu, D., Wang, X., Jiang, X., Bando, Y., & Golberg, D. (2014). Highly Water-Soluble, Porous, and Biocompatible Boron Nitrides for Anticancer Drug Delivery. ACS Nano. https://doi.org/10.1021/nn5014808
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
