Cited by 127Assisted Reproductive Technology and Twin PregnancyPrenatal Screening and DiagnosticsCongenital Anomalies and Fetal Surgery

First‐trimester ultrasound determination of chorionicity in twin pregnancy

Dias, T., Arcangeli, T., Bhide, A., Napolitano, R., Mahsud‐Dornan, S., Thilaganathan, B.·2011·Ultrasound in Obstetrics & Gynecology

Abstract

Objective: To determine the accuracy of ultrasound at 11–14 weeks' gestation in the diagnosis of chorionicity in twin pregnancy. Methods: This was a retrospective observational study of data obtained between 1999 and 2010. At the first‐trimester routine ultrasound scan, chorionicity was assigned according to the number of placental masses and T or λ‐signs for a single placental mass. Chorionicity was confirmed by histology or discordant sex at birth. Results: A total of 648 pregnancies were assigned chorionicity by first‐trimester ultrasound during the study period. Chorionicity was ascertained in 613 cases, either by histology (n = 340) or discordant sex (n = 273). Chorionicity was correctly assigned by ultrasound at 11–14 weeks in 612 of 613 pregnancies (accuracy 99.8%). Sensitivity and specificity for determining monochorionicity were 100% and 99.8%, respectively. Conclusions: First‐trimester ultrasound can be used to determine chorionicity reliably by noting the number of placental masses and T or λ‐signs. Determination of twin chorionicity is important and should be completed in the first trimester. Copyright © 2011 ISUOG. Published by John Wiley & Sons, Ltd.

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Crossref · 10.1002/uog.8956

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Authors
Dias, T., Arcangeli, T., Bhide, A., Napolitano, R., Mahsud‐Dornan, S., & Thilaganathan, B.
Affiliations
St George's, University of London (GB)
Corresponding author
Thilaganathan, B.
Venue
Ultrasound in Obstetrics & Gynecology
Publisher
Wiley
Published
2011-05-03
Volume
38
Issue
5
Pages
530-532
ISSN
  • 0960-7692 (ISSN-L)
  • 1469-0705
OpenAlex
W2020721181
Cited by
127
References
16
Citations by year
2026: 4 · 2025: 1 · 2024: 4 · 2023: 8 · 2022: 8 · 2021: 14 · 2020: 19 · 2019: 2 · 2018: 7 · 2017: 8 · 2016: 9 · 2015: 9 · 2014: 5 · 2013: 17 · 2012: 9
FWCI
9.74
Type
journal article
Language
en
Open access
closed
Locations
  • Ultrasound in Obstetrics and Gynecology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Assisted Reproductive Technology and Twin Pregnancy
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Screening and Diagnostics
  • Health Sciences › Medicine › Surgery › Congenital Anomalies and Fetal Surgery
Keywords
twin pregnancy, chorionicity, monochorionic twins, dichorionic twins, first-trimester ultrasound, placental mass, T-sign, lambda sign, diagnostic accuracy, histopathological confirmation
MeSH terms
Chorion, Female, Humans, Placenta, Pregnancy, Pregnancy Trimester, First, Retrospective Studies, Sensitivity and Specificity, Ultrasonography, Prenatal, Pregnancy, Twin

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