Do we really need a process-based approach to psychotherapy?
Open accessAbstract
Hayes and Hofmann1 discuss the neglect of processes of change in psychotherapy and the lessons we can learn from process research in the context of “third-wave” cognitive behavioral therapies (CBTs). They criticize the notion of psychiatric syndromes and argue that these newer therapies should be considered in the context of an idiographic approach to process-based functional analysis. Although I do agree upon several of the arguments the authors put forward, there are a few issues on which my views are somewhat different. As to their critic to the latent disease model of psychiatry, they do not discuss the progress which is now being made by the network approach. This approach to psychopathology posits that mental disorders can be conceptualized as causal systems of mutually reinforcing symptoms2. The model has been used over the past decade to examine psychiatric comorbidity and developmental psychopathology, and is being applied to a variety of specific disorders, such as anxiety disorders, autism, depression, post-traumatic stress disorder, eating disorders, psychosis and psychopathy. Hayes and Hofmann argue that in the 1980s the golden era of “protocols for syndromes” settled in, with an ignorance of the therapeutic processes involved in these CBT protocols. This observation may be partly correct, but it is important to note that the CBT movement has always emphasized the role of theory, and of basic research supporting this theory3. Nevertheless, the dominant paradigm has indeed been evidence-based treatment. Expert committees have been providing guidelines for evidence-based treatment of mental disorders, thus “certifying” a given treatment for a given population based on its proven efficacy for that specific mental disorder in randomized controlled trials (RCTs). It should be acknowledged that this approach has led to a number of evidence-based CBT treatments for many mental disorders4. At the same time, about 30-40% of patients cannot be successfully treated with current CBT protocols, including “third-wave” CBTs, such as acceptance and commitment therapy (ACT), compassion-focused therapy, mindfulness-based cognitive therapy (MBCT), meta-cognitive therapy, and functional analytic psychotherapy. Although “third-wave” therapies are more experiential and “may lead to positive outcomes for trainees and practitioners”1, there is no robust evidence that they are more effective than classic behavior therapies or “second wave” CBTs5, 6. One important way to investigate mechanisms of change is mediation. Several potential mediators have been proposed in the literature in relation to depression. Cognitive theory states that depression is caused and maintained by dysfunctional cognitions and maladaptive information processing strategies, and depression severity can be reduced by altering the function, content and structure of cognitions associated with negative affect, as is done in CBT. Changing the content of thoughts is seen as an unnecessary step in ACT, as it is assumed that distancing oneself from thoughts is a sufficient and more productive way to diminish the influence of thoughts on behavior. Distancing is achieved through the process of defusion or decentering. In an RCT7, manualized CBT was compared with ACT, and patients in both conditions reported significant and large reductions of depressive symptoms aa well as improvement in quality of life up to 12 months after treatment. Interestingly, dysfunctional cognitions did not only mediate treatment effects of depressive symptoms in CBT, but also in ACT. On the other hand, decentering mediated not only treatment effects in ACT, but also in CBT. Thus, both treatments seem to work through changes in dysfunctional cognitions and decentering, even though the treatments differ substantially. Another interesting issue for further research is the role of the therapeutic alliance in CBT and “third-wave” therapies. In an RCT8, the alliance-outcome association in CBT vs. MBCT was evaluated in diabetic patients with depressive symptoms. Because both CBT and MBCT therapists aim to form a therapeutic bond by adopting an open, empathic, accepting, and non-judging attitude towards patients, it was hypothesized that the therapeutic bond was going to predict the subsequent symptom change in both treatments. The results showed, however, that patients’ ratings of the therapeutic alliance predicted depressive symptom improvement in CBT, but not in MBCT. There is a clear need for further studies into the role of the therapeutic alliance in “third-wave” therapies. Although the empirically supported treatment approach is currently still followed by a majority of CBT researchers and practitioners, a growing minority argues for the need to put greater emphasis on individual case formulation based on empirically tested theories instead of treatment protocols. Hayes and Hofmann suggest to study processes of change in therapy using idiographic analysis for nomothetic purpo
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- Findingnone given§ Lutz & Schwartz
In a prospective evaluation of 538 patients, patients treated with the recommended strategy during the first ten sessions had better outcomes, with an effect size of about 0.3.
“The prospective evaluation on 538 patients showed an advantage in outcomes, with an effect size of about 0.3, when patients were treated with the recommended strategy during the first ten sessions.”
Quote in the paperSubstantial claim - Findingown data§ Challenges in the evolution toward process-based interventions
In one clinical trial aimed at decreasing symptoms of depression, participants with an ICD-10 diagnosis of a depressive condition reported 5 to 15 additional psychological problems.
“In one of our clinical trials aimed at decreasing the symptoms of depression 2 , participants with an ICD-10 diagnosis of a depressive condition reported 5 to 15 additional psychological problems.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [2] 2. Robinaugh DJ, Hoekstra RHA, Toner ER et al. Psychol Med 2020;50:353-66.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Premisecitation§ Do we really need a process-based approach to psychotherapy?
The evidence-based treatment approach has led to a number of evidence-based CBT treatments for many mental disorders.
“It should be acknowledged that this approach has led to a number of evidencebased CBT treatments for many mental dis orders 4 .”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [4] 4. Emmelkamp PMG. In Lambert MJ (ed). Ber- gin and Garfield's handbook of psychotherapy and behavior change, 6th ed. New York: Wiley, 2013:343-92.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Premisecitation§ Lutz & Schwartz
The Leeds Risk Index (LRI) was developed based on a sample of 1,347 patients and prognostically tested on 282 patients in the IAPT programme to recommend either low or high intensity treatments.
“A similar approach, the Leeds Risk Index (LRI), was developed based on a sample of 1,347 patients and prognostically tested on 282 patients in the Improving Access to Psychological Therapies (IAPT) programme, to recommend either low or high intensity treatments 7 .”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [7] 7. A-Tjak JGL, Morina N, Topper M et al. BMC Psychiatry 2021;21:41.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Premisecitation§ Do we really need a process-based approach to psychotherapy?
Dysfunctional cognitions mediated treatment effects of depressive symptoms in both CBT and ACT.
“Interestingly, dysfunctional cognitions did not only mediate treatment effects of depressive symptoms in CBT, but also in ACT.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [7] 7. A-Tjak JGL, Morina N, Topper M et al. BMC Psychiatry 2021;21:41.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Premisecitation§ Do we really need a process-based approach to psychotherapy?
The CBT movement has always emphasized the role of theory and of basic research supporting this theory.
“This observation may be partly correct, but it is important to note that the CBT movement has always emphasized the role of theory, and of basic research supporting this theory 3 .”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [3] 3. Emmelkamp PMG, Ehring T, Powers MB. In: Kazantis N, Reinecke MA, Freeman A (eds). Cognitive and behavior theories in clinical prac tice. New York: Guilford, 2010:1-27.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Interpretationown data§ Challenges in the evolution toward process-based interventions
Several significant behavioral problems can be overlooked and left untreated if treatment providers only focus on one or two syndrome categories.
“Several significant behavioral problems can be overlooked and left untreated if the treatment providers only focus on one or two syndrome categories.”
Quote in the paperSubstantial claim - Premisecitation§ Do we really need a process-based approach to psychotherapy?
In that study, only about one half of children in the control condition actually engaged in behavioral health services.
“However, only about one half of children in the control condition actually engaged in behavioral health services.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [9] 9. Burke JD, Loeber R. J Abnorm Child Psychol 2016; 44:179-89. DOI:10.1002/wps.20889
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Premisecitation§ Do we really need a process-based approach to psychotherapy?
In an RCT, patients' ratings of the therapeutic alliance predicted depressive symptom improvement in CBT, but not in MBCT.
“The results showed, however, that patients' ratings of the therapeutic alliance predicted depressive symptom improvement in CBT, but not in MBCT.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [8] 8. Snippe E, Fleer J, Tovote A et al. Psychother Psychosom 2015;84:314-5.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Premisecitation§ Do we really need a process-based approach to psychotherapy?
There is no robust evidence for a superior effectiveness of treatment based on functional analysis compared with manualized evidence-based treatments.
“Actually, there is no robust evidence for a superior effectiveness of treatment based on functional analysis compared with manualized evidence-based treatments 2 .”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [2] 2. Robinaugh DJ, Hoekstra RHA, Toner ER et al. Psychol Med 2020;50:353-66.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Premisecitation§ Do we really need a process-based approach to psychotherapy?
Decentering mediated treatment effects in both ACT and CBT.
“On the other hand, decentering mediated not only treatment effects in ACT, but also in CBT.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [7] 7. A-Tjak JGL, Morina N, Topper M et al. BMC Psychiatry 2021;21:41.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Classified as probably not a substantial claim. 3
- May combine two claims. 4
Classified as probably not a substantial claim.
Premisecitation§ Lutz & SchwartzStratified care using the LRI improves efficiency by generating comparable outcomes with less treatment sessions.
“Results indicated that such stratified care improves efficiency by generating comparable outcomes with less treatment sessions.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [7] 7. A-Tjak JGL, Morina N, Topper M et al. BMC Psychiatry 2021;21:41.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
Premisecitation§ Do we really need a process-based approach to psychotherapy?In an RCT, manualized CBT was compared with ACT, and patients in both conditions reported significant and large reductions of depressive symptoms as well as improvement in quality of life up to 12 months after treatment.
“In an RCT 7 , manualized CBT was compared with ACT, and patients in both conditions reported significant and large reductions of depressive symptoms aa well as improvement in quality of life up to 12 months after treatment.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [7] 7. A-Tjak JGL, Morina N, Topper M et al. BMC Psychiatry 2021;21:41.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S3 (load-bearing).
Premisecitation§ Do we really need a process-based approach to psychotherapy?The network approach to psychopathology posits that mental disorders can be conceptualized as causal systems of mutually reinforcing symptoms.
“This approach to psychopathology posits that mental disorders can be conceptualized as causal systems of mutually reinforcing symptoms 2 .”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [2] 2. Robinaugh DJ, Hoekstra RHA, Toner ER et al. Psychol Med 2020;50:353-66.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
Premisecitation§ Lutz & SchwartzTherapist symptom awareness, attitude, and confidence using the system were significant predictors of outcome, while therapist-rated usefulness of feedback moderated the feedback-outcome association.
“Furthermore, therapist symptom awareness, attitude, and confidence using the system were found to be significant predictors of outcome, while therapist-rated usefulness of such feedback moderated the feedback-outcome association 2,8 .”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [2] 2. Robinaugh DJ, Hoekstra RHA, Toner ER et al. Psychol Med 2020;50:353-66.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites [8] 8. Snippe E, Fleer J, Tovote A et al. Psychother Psychosom 2015;84:314-5.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
Interpretationcitation§ Do we really need a process-based approach to psychotherapy?Both CBT and ACT seem to work through changes in dysfunctional cognitions and decentering, even though the treatments differ substantially.
“Thus, both treatments seem to work through changes in dysfunctional cognitions and decentering, even though the treatments differ substantially.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
Premisecitation§ Do we really need a process-based approach to psychotherapy?In one study, an individualized approach was found to be more effective than standard treatment in children with behavioral problems.
“In one of these studies 9 , an individualized approach was found to be more effective than standard treatment in children with behavioral problems.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [9] 9. Burke JD, Loeber R. J Abnorm Child Psychol 2016; 44:179-89. DOI:10.1002/wps.20889
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
Interpretationown data§ Challenges in the evolution toward process-based interventionsDiagnoses do not sufficiently account for individual differences, and additional information is usually needed to implement a psychological intervention.
“Diagnoses do not sufficiently account for individual differences, and additional information is usually needed to implement a psychological intervention.”
Quote in the paperSubstantial claim
Cites
Bergin and Garfield's Handbook of Psychotherapy and Behavior Change
Lambert, M. J. (2003) · Cited by 3,383 · see citing works
A-Tjak, J. G. L., Davis, M. L., Morina, N., Powers, M. B., Smits, J. A. J., & Emmelkamp, P. M. G. (2015) · Psychotherapy and Psychosomatics · doi:10.1159/000365764 · Cited by 921 · see citing works
Self-citationRobinaugh, D. J., Hoekstra, R. H. A., Toner, E. R., & Borsboom, D. (2020) · Psychological Medicine · doi:10.1017/s0033291719003404 · Cited by 861 · see citing works
Hayes, S. C., & Hofmann, S. G. (2021) · World Psychiatry · doi:10.1002/wps.20884 · Cited by 260 · see citing works
Tovote, K. A., Fleer, J., Snippe, E., Peeters, A. C. T. M., Emmelkamp, P. M. G., Sanderman, R., Links, T. P., & Schroevers, M. J. (2014) · Diabetes Care · doi:10.2337/dc13-2918 · Cited by 163 · see citing works
Self-citationA-Tjak, J. G. L., Morina, N., Topper, M., & Emmelkamp, P. M. G. (2021) · BMC Psychiatry · doi:10.1186/s12888-020-03020-1 · Cited by 57 · see citing works
Self-citationBurke, J. D., & Loeber, R. (2016) · Journal of Abnormal Child Psychology · doi:10.1007/s10802-015-9975-0 · Cited by 45 · see citing works
Snippe, E., Fleer, J., Tovote, K. A., Sanderman, R., Emmelkamp, P. M. G., & Schroevers, M. J. (2015) · Psychotherapy and Psychosomatics · doi:10.1159/000379755 · Cited by 14 · see citing works
Self-citation
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Research works printed but not linked: 1
- Emmelkamp PMG, 2010, Cognitive and behavior theories in clinical practice, 1
Cited by
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Schefft, C., Heinitz, C., Guhn, A., Brakemeier, E., Sterzer, P., & Köhler, S. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1189970 · Cited by 22 · see citing works
“In the past decades, various new psychotherapeutic approaches have been developed, aiming to improve current ones (6, 15).”
BackgroundRohlfing, N., Pum, M. E., Bonnet, U., Koelkebeck, K., & Scherbaum, N. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1549976 · Cited by 2 · see citing works
- Authors
- Emmelkamp, P. M. G.
- Affiliations
- Institut d'Etudes Avancées Paris (FR)
- Corresponding author
- Emmelkamp, Paul M.G.
- ORCID
- Emmelkamp, Paul M.G.
- Venue
- World Psychiatry
- Publisher
- Wiley
- Published
- 2021-09-09
- Volume
- 20
- Issue
- 3
- Pages
- 381-382
- ISSN
- 1723-8617 (ISSN-L)
- 2051-5545
- PMC
- PMC8429340
- OpenAlex
- W3198227210
- Semantic Scholar
- 3a58c72af6cd309f1d439ea8bb78166dc73963e2
- Cited by
- 2
- References
- 8
- Citations by year
- 2025: 1 · 2023: 1
- FWCI
- 0.17
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- World Psychiatry (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Keywords
- psychotherapy process research, mechanisms of change, third-wave cognitive behavioral therapy, evidence-based treatment, treatment-resistant depression, mediation analysis, functional analytic psychotherapy, acceptance and commitment therapy, compassion-focused therapy, mindfulness-based cognitive therapy, psychiatric syndromes, idiographic approach
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