An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

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    Chi Chen, Angela Kong · 2004 · Free Radical Biology and Medicine
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    Chen, Xin, Drew, Joshua, Berney, Wren, Lei, Wei · 2021 · Cells
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     Toshihiko Ogura, Kit I. Tong, Kazuhiro Mio, Yuusuke Maruyama, Hirofumi Kurokawa, Chikara Sato, Masayuki P. Yamamoto · 2010 · Proceedings of the National Academy of Sciences