The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Isolation and Initial Characterization of a Novel Zinc Finger Gene, DNMT3L, on 21q22.3, Related to the Cytosine-5- Methyltransferase 3 Gene Family
Open accessAbstract
We have isolated the DNMT3L gene that is related to the cytosine-5-methyltransferase 3 (DNMT3) family. The gene is located on chromosome 21q22.3 between the AIRE and the KIAA0653 genes and spans approximately 16 kb of genomic sequence. The encoded protein of 387 amino acids has a cysteine-rich region containing a novel-type zinc finger domain that is conserved in DNMT3A and DNMT3B but also in ATRX, a member of the SNF2 protein family. The novel domain, called an ADD (ATRX, DNMT3, DNMT3L)-type zinc finger, contains two subparts: a C2C2 and an imperfect PHD zinc finger. Expression of the DNMT3L mRNA was not detectable by Northern blotting; however, RT-PCR amplification revealed that it is expressed at low levels in several tissues including testis, ovary, and thymus.
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Cited by
DNA methylation and its basic function
Moore, L. D., Le, T., & Fan, G. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2012.112 · Cited by 4,906
EUKARYOTIC CYTOSINE METHYLTRANSFERASES
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Dnmt3a binds deacetylases and is recruited by a sequence‐specific repressor to silence transcription
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Metadata
- Authors
- Aapola, U., Shibuya, K., Scott, H. S., Ollila, J., Vihinen, M., Heino, M., Shintani, A., Kawasaki, K., Minoshima, S., Krohn, K., Antonarakis, S. E., Shimizu, N., Kudoh, J., & Peterson, P.
- Venue
- Genomics
- Publisher
- Elsevier BV
- Published
- 2000-05
- Volume
- 65
- Issue
- 3
- Pages
- 293-298
- ISSN
- 0888-7543 (ISSN-L)
- OpenAlex
- W2059123635
- Cited by
- 317
- References
- 17
- FWCI
- 3.60
- Type
- journal article
- Language
- en
- Open access
- green
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- Aapola, U., Shibuya, K., Scott, H. S., Ollila, J., Vihinen, M., Heino, M., Shintani, A., Kawasaki, K., Minoshima, S., Krohn, K., Antonarakis, S. E., Shimizu, N., Kudoh, J., & Peterson, P. (2000). Isolation and Initial Characterization of a Novel Zinc Finger Gene, DNMT3L, on 21q22.3, Related to the Cytosine-5- Methyltransferase 3 Gene Family. Genomics. https://doi.org/10.1006/geno.2000.6168
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