The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Metabolic Engineering of Osmoprotectant Accumulation in Plants
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Plant productivity and environment
Boyer, J. S. (1982) · Science · doi:10.1126/science.218.4571.443 · Cited by 3,959
(1992) · doi:10.1007/978-3-642-76682-4 · Cited by 182
Research works printed but not linked: 50
- Alia, 1999, Enhanced tolerance to light stress of transgenic Arabidopsis plants that express the codA gene for a bacterial choline oxidase, Plant Mol. Biol., 40, 279, 10.1023/A:1006121821883 · doi:10.1023/a:1006121821883
- Andresen, 1988, Molecular cloning, physical mapping and expression of the bet genes governing the osmoregulatory choline–glycine betaine pathway of Escherichia coli, J. Gen. Microb., 134, 1737
- Bohnert, 1995, Adaptations to environmental stresses, Plant Cell, 7, 1099, 10.1105/tpc.7.7.1099 · DOI · Paper page
- De Wilde, 2000, Plants as bioreactors for protein production: Avoiding the problem of transgene silencing, Plant Mol. Biol., 43, 347, 10.1023/A:1006464304199 · DOI · Paper page
- Fiehn, 2000, Metabolite profiling for plant functional genomics, Nat. Biotechnol., 18, 1157, 10.1038/81137 · DOI · Paper page
- Galili, 1995, Regulation of lysine and threonine synthesis, Plant Cell, 7, 899, 10.1105/tpc.7.7.899 · doi:10.1105/tpc.7.7.899
- Goddijn, 1999, Trehalose metabolism in plants, Trends Plant Sci., 4, 315, 10.1016/S1360-1385(99)01446-6 · DOI · Paper page
- Goddijn, 1997, Inhibition of trehalase activity enhances trehalose accumulation in transgenic plants, Plant Physiol., 113, 181, 10.1104/pp.113.1.181 · DOI · Paper page
- Hayashi, 1997, Transformation of Arabidopsis thaliana with the codA gene for choline oxidase: Accumulation of glycinebetaine and enhanced tolerance to salt and cold stress, Plant J., 12, 133, 10.1046/j.1365-313X.1997.12010133.x · DOI · Paper page
- Holmstrom, 1996, Drought tolerance in tobacco, Nature, 379, 683, 10.1038/379683a0 · DOI · Paper page
- Holmstrom, 2000, Improved tolerance to salinity and low temperature in transgenic tobacco producing glycine betaine, J. Exp. Bot., 51, 177, 10.1093/jexbot/51.343.177 · DOI · Paper page
- Hong, 2000, Removal of feedback inhibition of delta1-pyrroline-5-carboxylate synthetase results in increased proline accumulation and protection of plants from osmotic stress, Plant Physiol., 122, 1129, 10.1104/pp.122.4.1129 · DOI · Paper page
- Huang, 2000, Genetic engineering of glycinebetaine production toward enhancing stress tolerance in plants: Metabolic limitations, Plant Physiol., 122, 747, 10.1104/pp.122.3.747 · DOI · Paper page
- Ikuta, 1977, Purification and characterization of choline oxidase from Arthrobacter globiformis, J. Biochem., 82, 1741, 10.1093/oxfordjournals.jbchem.a131872 · DOI · Paper page
- Iturriaga, 2000, New desiccation-tolerant plants, including a grass, in the central highlands of Mexico, accumulate trehalose, Aust. J. Bot., 48, 153, 10.1071/BT98062 · DOI
- Kishor, 1995, Overexpression of delta1-pyrroline-5-carboxylate synthetase increases proline production and confers osmotolerance in transgenic plants, Plant Physiol., 108, 1387, 10.1104/pp.108.4.1387 · DOI · Paper page
- Landfald, 1986, Choline–glycine betaine pathway confers a high level of osmotic tolerance in Escherichia coli, J. Bacteriol., 165, 849, 10.1128/jb.165.3.849-855.1986 · DOI · Paper page
- LeRudulier, 1984, Molecular biology of osmoregulation, Science, 224, 1064, 10.1126/science.224.4653.1064 · DOI · Paper page
- Lilius, 1996, Enhanced NaCl stress tolerance in transgenic tobacco expressing bacterial choline dehydrogenase, Biotechnology, 14, 177, 10.1038/nbt0296-177 · DOI · Paper page
- McNeil, 2000, Radiotracer and computer modeling evidence that phospho-base methylation is the main route of choline synthesis in tobacco, Plant Physiol., 123, 371, 10.1104/pp.123.1.371 · DOI
- McNeil, 2001, Enhanced synthesis of choline and glycine betaine in transgenic tobacco plants that overexpress phosphoethanolamine N-methyltransferase, Proc. Natl. Acad. Sci. USA, 10.1073/pnas.171228998 · doi:10.1073/pnas.171228998
- McNeil, 2000, Metabolic modeling identifies key constraints on an engineered glycine betaine synthesis pathway in tobacco, Plant Physiol., 124, 153, 10.1104/pp.124.1.153 · doi:10.1104/pp.124.1.153
- Muller, 1995, Trehalose and trehalase in plants: Recent developments, Plant Sci., 112, 1, 10.1016/0168-9452(95)04218-J · DOI · Paper page
- Nakayama, 2000, Ectoine, the compatible solute of Halomonas elongata, confers hyperosmotic tolerance in cultured tobacco cells, Plant Physiol., 122, 1239, 10.1104/pp.122.4.1239 · DOI · Paper page
- Nawrath, 1994, Targeting of the polyhydroxybutyrate biosynthetic pathway to the plastids of Arabidopsis thaliana results in high levels of polymer accumulation, Proc. Natl. Acad. Sci. USA, 91, 12760, 10.1073/pnas.91.26.12760 · DOI
- Nuccio, 2000, Choline import into chloroplasts limits glycine betaine synthesis in tobacco: Analysis of plants engineered with a chloroplastic or a cytosolic pathway, Metab. Eng., 2, 300, 10.1006/mben.2000.0158 · DOI
- Nuccio, 1999, Metabolic engineering of plants for osmotic stress resistance, Curr. Opin. Plant Biol., 2, 128, 10.1016/S1369-5266(99)80026-0 · DOI · Paper page
- Nuccio, 1998, The endogenous choline supply limits glycine betaine synthesis in transgenic tobacco expressing choline monooxygenase, Plant J., 16, 487, 10.1046/j.1365-313x.1998.00316.x · DOI · Paper page
- Nuccio, 2000, cDNA cloning of phosphoethanolamine N-methyltransferase from spinach by complementation in Schizosaccharomyces pombe and characterization of the recombinant enzyme, J. Biol. Chem., 275, 14095, 10.1074/jbc.275.19.14095 · DOI
- Nyyssola, 2000, Extreme halophiles synthesize betaine from glycine by methylation, J. Biol. Chem., 275, 22196, 10.1074/jbc.M910111199 · DOI · Paper page
- Ono, 1999, Characterization of biosynthetic enzymes for ectoine as a compatible solute in a moderately halophilic eubacterium, Halomonas elongata, J. Bacteriol., 181, 91, 10.1128/JB.181.1.91-99.1999 · DOI · Paper page
- Pilon-Smits, 1998, Trehalose-producing transgenic tobacco plants show improved growth performance under drought stress, J. Plant Physiol., 152, 525, 10.1016/S0176-1617(98)80273-3 · DOI · Paper page
- Rathinasabapathi, 1997, Choline monooxygenase, an unusual iron-sulfur enzyme catalyzing the first step of glycine betaine synthesis in plants: Prosthetic group characterization and cDNA cloning, Proc. Natl. Acad. Sci. USA, 94, 3454, 10.1073/pnas.94.7.3454 · DOI · Paper page
- Rathinasabapathi, 1994, Metabolic engineering of glycine betaine synthesis: Plant betaine aldehyde dehydrogenases lacking typical transit peptides are targeted to tobacco chloroplasts where they confer betaine aldehyde resistance, Planta, 193, 155, 10.1007/BF00192524 · DOI
- Rhodes, 1993, Quaternary ammonium and tertiary sulfonium compounds in higher plants, Annu. Rev. Plant Physiol. Plant Mol. Biol., 44, 357, 10.1146/annurev.pp.44.060193.002041 · doi:10.1146/annurev.pp.44.060193.002041 · Paper page
- Romero, 1997, Expression of the yeast trehalose-6-phosphate synthase gene in transgenic tobacco plants: Pleiotropic phenotypes include drought tolerance, Planta, 201, 293, 10.1007/s004250050069 · DOI · Paper page
- Rontein, 2001, Plants synthesize ethanolamine by direct decarboxylation of serine using a pyridoxal phosphate enzyme, J. Biol. Chem., 276, 35523, 10.1074/jbc.M106038200 · DOI · Paper page
- Sakamoto, 2001, The use of bacterial choline oxidase, a glycinebetaine-synthesizing enzyme, to create stress-resistant transgenic plants, Plant Physiol., 125, 180, 10.1104/pp.125.1.180 · DOI
- Sakamoto, 1998, Metabolic engineering of rice leading to biosynthesis of glycinebetaine and tolerance to salt and cold, Plant Mol. Biol., 38, 1011, 10.1023/A:1006095015717 · DOI · Paper page
- Sakamoto, 2000, Transformation of Arabidopsis with the codA gene for choline oxidase enhances freezing tolerance of plants, Plant J., 22, 449, 10.1046/j.1365-313X.2000.00749.x · DOI
- Sheveleva, 1997, Increased salt and drought tolerance by D-ononitol production in transgenic Nicotiana tabacum L, Plant Physiol., 115, 1211, 10.1104/pp.115.3.1211 · DOI · Paper page
- Sheveleva, 1998, Sorbitol-6-phosphate dehydrogenase expression in transgenic tobacco: High amounts of sorbitol lead to necrotic lesions, Plant Physiol., 117, 831, 10.1104/pp.117.3.831 · DOI
- Somerville, 2000, Genomics: Plant biology in 2010, Science, 290, 2077, 10.1126/science.290.5499.2077 · DOI
- Tao, 1995, Sorbitol synthesis in transgenic tobacco with apple cDNA encoding NADP-dependent sorbitol-6-phosphate dehydrogenase, Plant Cell Physiol., 36, 525, 10.1093/oxfordjournals.pcp.a078789 · doi:10.1093/oxfordjournals.pcp.a078789
- Tarczynski, 1992, Expression of a bacterial mtlD gene in transgenic tobacco leads to production and accumulation of mannitol, Proc. Natl. Acad. Sci. USA, 89, 2600, 10.1073/pnas.89.7.2600 · DOI · Paper page
- Thomas, 1995, Enhancement of seed germination in high salinity by engineering mannitol expression in Arabidopsis thaliana, Plant Cell Environ., 18, 801, 10.1111/j.1365-3040.1995.tb00584.x · DOI · Paper page
- Trethewey, 2001, Gene discovery via metabolic profiling, Curr. Opin. Biotechnol., 12, 135, 10.1016/S0958-1669(00)00187-7 · DOI
- Vernon, 1993, Cyclitol production in transgenic tobacco, Plant J., 4, 199, 10.1046/j.1365-313X.1993.04010199.x · DOI
- Weretilnyk, 1995, Enzymes of choline synthesis in spinach—response of phospho-base N-methyltransferase activities to light and salinity, Plant Physiol., 109, 1085, 10.1104/pp.109.3.1085 · doi:10.1104/pp.109.3.1085
- Zhu, 2000, Large-scale profiling of the Arabidopsis transcriptome, Plant Physiol., 124, 1472, 10.1104/pp.124.4.1472 · DOI
Cited by
Zong, J., Chen, P., Luo, Q., Gao, J., Qin, R., Wu, C., Lv, Q., Zhao, T., & Fu, Y. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241814398 · Cited by 27
Metadata
- Authors
- Rontein, D., Basset, G., & Hanson, A. D.
- Venue
- Metabolic Engineering
- Publisher
- Elsevier BV
- Published
- 2002-01
- Volume
- 4
- Issue
- 1
- Pages
- 49-56
- ISSN
- 1096-7176 (ISSN-L)
- OpenAlex
- W2014338522
- Cited by
- 433
- References
- 2
- FWCI
- 18.40
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Metabolic Engineering of Osmoprotectant Accumulation in Plants. https://app.cochat.ai/papers/10.1006/mben.2001.0208
- The paper
- Rontein, D., Basset, G., & Hanson, A. D. (2002). Metabolic Engineering of Osmoprotectant Accumulation in Plants. Metabolic Engineering. https://doi.org/10.1006/mben.2001.0208
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.