Oncogenic Roles of the PI3K/AKT/mTOR axis
Aoki, Masahiro, Fujishita, Teruaki·2017·Current topics in microbiology and immunology
Cited by (358)
Items 101–200 of 358
- MicroRNAs involved in the EGFR pathway in glioblastomaBin Xu, Jie Mei, Wei Ji, Zhengyuan Huo, Zheng Bian, Jiantong Jiao, Xiaoqing Li, Jun Sun, Junfei Shao · 2020 · Biomedicine & Pharmacotherapy
- Novel Ferrocene Derivatives Induce Apoptosis through Mitochondria-Dependent and Cell Cycle Arrest via PI3K/Akt/mTOR Signaling Pathway in T Cell Acute Lymphoblastic LeukemiaLiao Zeng, Mingqing Tang, Chao Pi, Jianrong Zheng, Sanxing Gao, Titaua Chabanne, Rémi Chauvin, Wenzhao Cheng, Hongjun Lin, Ruian Xu et al. · 2021 · Cancers
- PKI-587 enhances radiosensitization of hepatocellular carcinoma by inhibiting the PI3K/AKT/mTOR pathways and DNA damage repairYinghai Xie, Changwei Liu, Yinci Zhang, Amin Li, Chong Sun, Rui Li, Yingru Xing, Minghong Shi, Qi Wang · 2021 · PLoS ONE
- BRAF-activated WT1 contributes to cancer growth and regulates autophagy and apoptosis in papillary thyroid carcinomaXing Chen, Shan Lin, Ying Q. Lin, Songsong Wu, Minling Zhuo, Ailong Zhang, Junjie Zheng, Zhenhui You · 2022 · Journal of Translational Medicine
- On the Core Prescriptions and Their Mechanisms of Traditional Chinese Medicine in Hepatitis B, Liver Cirrhosis, and Liver Cancer TreatmentZhendong Wang, Yong Zhang, Qiuyun Zhang, Qiang Ao, Changyong Luo, Bochuan Wang, Chen Bai, Xueyi Ge, Yuhan Wang, Jing Wang et al. · 2022 · Journal of Oncology
- Overexpression of YEATS2 Remodels the Extracellular Matrix to Promote Hepatocellular Carcinoma Progression via the PI3K/AKT PathwayXin Liu, Yi Hu, Cairong Li, Jiayu Chen, Xiaohong Liu, Yang Shen, Yangtao Xu, Wenliang Chen, Ximing Xu · 2023 · Cancers
- Zinc Inhibits Lead-Induced Oxidative Stress and Apoptosis of ST Cells Through ROS/PTEN/PI3K/AKT AxisHaoyu Zhang, Kexin Sun, Meichen Gao, Shiwen Xu · 2023 · Biological Trace Element Research
- The Role of Long Non-Coding RNA NNT-AS1 in Neoplastic DiseaseCong Zhou, Shiwei Duan · 2020 · Cancers
- High PYGL Expression Predicts Poor Prognosis in Human GliomasChangyi Zhao, Chun-hui Hua, Changhua Li, Ruizhe Zheng, Xinyuan Li · 2021 · Frontiers in Neurology
- Inhibitory Effect of Gallotannin on Lung Metastasis of Metastatic Colorectal Cancer Cells by Inducing Apoptosis, Cell Cycle Arrest and AutophagyJeong‐Geon Mun, Yohan Han, Hee-Dong Jeon, Dae Hwan Yoon, Yeong Gyeong Lee, Seung‐Heon Hong, Ji‐Ye Kee · 2021 · The American Journal of Chinese Medicine
- Transcriptome profiling of cervical cancer cells acquired resistance to cisplatin by deep sequencingYamin Wang, Linna Liu, Zhong Chen · 2019 · Artificial Cells Nanomedicine and Biotechnology
- Role of bioactive peptides derived from food proteins in programmed cell death to treat inflammatory diseases and cancerZhao Deng, Zhipeng Yang, Jian Peng · 2021 · Critical Reviews in Food Science and Nutrition
- Emerging role of extracellular vesicles and exogenous stimuli in molecular mechanisms of peripheral nerve regenerationYara Izhiman, Leyla Esfandiari · 2024 · Frontiers in Cellular Neuroscience
- Current Molecular Targeted Agents for Advanced Gastric CancerShanshan Nie, Guoping Yang, Hongwei Lü · 2020 · OncoTargets and Therapy
- An Overview on Molecular Characterization of Thymic Tumors: Old and New Targets for Clinical AdvancesValentina Tateo, Lisa Manuzzi, Claudia Parisi, Andrea De Giglio, Davide Campana, Maria A. Pantaleo, Giuseppe Lamberti · 2021 · Pharmaceuticals
- Matrine exerts antitumor activity in cervical cancer by protective autophagy via the Akt/mTOR pathway in vitro and in vivoFan Zhang, Hua Zhang, Wenjun Qian, Yuyan Xi, Lihua Chang, Xiaoling Wu, Mu Li · 2022 · Oncology Letters
- Structural aspects of chemical modifications in the MHC-restricted immunopeptidome; Implications for immune recognitionTatyana Sandalova, Benedetta Maria Sala, Adnane Achour · 2022 · Frontiers in Chemistry
- Unleashing Intrinsic Growth Pathways in Regenerating Peripheral NeuronsTrevor M. Poitras, Douglas William Zochodne · 2022 · International Journal of Molecular Sciences
- The regulatory role of N6-methyladenosine RNA modification in gastric cancer: Molecular mechanisms and potential therapeutic targetsGaofeng Li, Qiru Fu, Cong Liu, Yuxi Peng, Jun Gong, Shilan Li, Yan Huang, Haiyuan Zhang · 2022 · Frontiers in Oncology
- Mechanism and Role of Endoplasmic Reticulum Stress in OsteosarcomaPeijun Zhu, Ting Li, Qingqing Li, Yawen Gu, Yuan Shu, Kaibo Hu, Leifeng Chen, Xiaogang Peng, Jie Peng, Liang Hao · 2022 · Biomolecules
- PHF5A facilitates the development and progression of gastric cancer through SKP2-mediated stabilization of FOSZhandong Zhang, Liangqun Peng, Wei Yang, Baodong Li, Yawei Hua, Suxia Luo · 2023 · Journal of Translational Medicine
- M6A-mediated upregulation of HOXC10 promotes human hepatocellular carcinoma development through PTEN/AKT/mTOR signaling pathwayMiao Li, Qianwen Guo, Qian Shi, Yanzhi Rao, Yixin Dong, Fangjie Chen, Xun Qi · 2023 · Discover Oncology
- The single‐cell evolution trajectory presented different hypoxia heterogeneity to reveal the carcinogenesis of genes in clear cell renal cell carcinoma: Based on multiple omics and real experimental verificationBaoluo Ma, Linghui Qin, Zhou Sun, Jingyu Wang, Lisa Jia Tran, Jing Zhang, Fangdie Ye, Yan Liu, Min Chen · 2023 · Environmental Toxicology
- QiShenYiQi pill improves the reparative myocardial fibrosis by regulating autophagyShichao Lv, Peng Yuan, Jianping Dong, Chunmiao Lu, Meng Li, Fan Qu, Yaping Zhu, Zhuo Yuan, Junping Zhang · 2020 · Journal of Cellular and Molecular Medicine
- Ginsenoside Rg1 Induces Autophagy in Colorectal Cancer through Inhibition of the Akt/mTOR/p70S6K PathwayRuiqi Liu, Bin Zhang, Shuting Zou, Li Cui, Lin Lin, Lingchang Li · 2024 · Journal of Microbiology and Biotechnology
- Significance of tumor mutation burden and immune infiltration in thymic epithelial tumorsZiming Wang, Qirong Xu, David Kaul, Mahmoud Ismail, Harun Badakhshi · 2021 · Thoracic Cancer
- PRMT4 promotes hepatocellular carcinoma progression by activating AKT/mTOR signaling and indicates poor prognosisPeng Du, Kaifeng Luo, Guoyong Li, Jisheng Zhu, Qi Xiao, Yong Li, Xingjian Zhang · 2021 · International Journal of Medical Sciences
- Notoginsenoside R1 Regulates Ischemic Myocardial Lipid Metabolism by Activating the AKT/mTOR Signaling PathwayWei Lei, Yiqi Yan, Yaolei Ma, Min Jiang, Boli Zhang, Han Zhang, Yuhong Li · 2022 · Frontiers in Pharmacology
- The diagnostic, prognostic role and molecular mechanism of miR-328 in human cancerZhichao Wang, Wenjie Xie, Hongzai Guan · 2022 · Biomedicine & Pharmacotherapy
- Autophagy as a dual-faced host response to viral infectionsHuanjie Zhai, Tao Wang, Di Liu, Li Pan, Yuan Sun, Hua‐Ji Qiu · 2023 · Frontiers in Cellular and Infection Microbiology
- MicroRNA‑122 acts as tumor suppressor by targeting TRIM29 and blocking the activity of PI3K/AKT signaling in nasopharyngeal carcinoma in�vitroYan Yang, Qing Li, Lili Guo · 2018 · Molecular Medicine Reports
- A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein ExpressionTing Wang, Jingjing Dong, Yuan Xu, Hao Wen, Linguangjin Wu, Jianwen Liu, Hua Xiu Sui, Wanli Deng · 2021 · Frontiers in Pharmacology
- The synergistic antitumor effect of IL-6 neutralization with NVP-BEZ235 in hepatocellular carcinomaYao Wang, Xiaolong Miao, Yuancong Jiang, Zelai Wu, Xuhang Zhu, Han Liu, Xiaoying Wu, Jinzhen Cai, Xianfeng Ding, Weihua Gong · 2022 · Cell Death and Disease
- Correlation of LAGE3 with unfavorable prognosis and promoting tumor development in HCC via PI3K/AKT/mTOR and Ras/RAF/MAPK pathwaysYun Li, Hui Fang Xiong · 2022 · BMC Cancer
- Repressing IRS1 /2 by NT157 inhibits the malignant behaviors of ovarian cancer through inactivating PI3K / AKT / mTOR pathway and inducing autophagyCaixia Li, Chuandi Men, Wei‐Hong Yang, Rong Chen, Jihui Zhu, Zhong‐Ping Cheng · 2023 · The Kaohsiung Journal of Medical Sciences
- Tenascin‑C promotes epithelial‑to‑mesenchymal transition and the mTOR signaling pathway in nasopharyngeal carcinomaXiang Cheng, Fen Li, Zezhang Tao · 2021 · Oncology Letters
- Xihuang pills induce apoptosis in hepatocellular carcinoma by suppressing phosphoinositide 3-kinase/protein kinase-B/mechanistic target of rapamycin pathwayYong-Jie Teng, Zhe Deng, Zhao-Guang Ouyang, Qing Zhou, Si Mei, Xing‐Xing Fan, Yongrong Wu, Hong-Ping Long, Le-Yao Fang, Dong-Liang Yin et al. · 2022 · World Journal of Gastrointestinal Oncology
- Recent advances in the development of inhibitors targeting KRAS-G12C and its related pathwaysDongqiang Zhao, Yu Liu, Fengchao Yi, Xia Zhao, Kui Lu · 2023 · European Journal of Medicinal Chemistry
- Profiles of PD‐1, PD‐L1, PD‐L2 in Gastric Cancer and Their Relation with Mutation, Immune Infiltration, and SurvivalJingwei Liu, Hao Ran Li, Liping Laura Sun, Yuan Yuan, Chengzhong Xing · 2020 · BioMed Research International
- The Synthetic Flavonoid Derivative GL-V9 Induces Apoptosis and Autophagy in Cutaneous Squamous Cell Carcinoma via Suppressing AKT-Regulated HK2 and mTOR SignalsYejin Zhu, Mengdi Liu, Jingyue Yao, Qinglong Guo, Libin Wei · 2020 · Molecules
- TNFAIP8 drives metabolic reprogramming to promote prostate cancer cell proliferationSuryakant K. Niture, Minghui Lin, Joab Otieno Odera, John T. Moore, Hong Zhe, Xiaoxin Luke Chen, Simeng Suy, Sean P. Collins, Deepak Kumar · 2020 · The International Journal of Biochemistry & Cell Biology
- Comprehensive analysis of transcriptomics and metabolomics to illustrate the underlying mechanism of helenalin against hepatic fibrosisYuhua Xiong, Shujuan Wen, Yan Li, Yuanyuan Wei, Bin Fang, Cuiyu Li, Quanfang Huang, Xing Lin · 2022 · European Journal of Pharmacology
- Transcriptomics Reveals the Mevalonate and Cholesterol Pathways Blocking as Part of the Bacterial Cyclodipeptides Cytotoxic Effects in HeLa Cells of Human Cervix AdenocarcinomaPedro Eduardo Lázaro-Mixteco, José Manuel González-Coronel, Laura Hernández-Padilla, Lorena Martínez Alcantar, Enrique Martínez-Carranza, Jesús Salvador López‐Bucio, Ángel Arturo Guevara-García, Jesús Campos‐García · 2022 · Frontiers in Oncology
- Annexin A1 affects tumor metastasis through epithelial-mesenchymal transition: a narrative reviewLulu Zheng, Lanxin Li, Baiqi Wang, Shanshan Zhang, Zhuqiong Fu, Ailan Cheng, Xiaoqiu Liang · 2022 · Translational Cancer Research
- The novel small molecule BH3 mimetic nobiletin synergizes with vorinostat to induce apoptosis and autophagy in small cell lung cancerYuqian Li, Fang Fan, Yuan-ru Wang, Lu-yao Li, Ya-jun Cao, Si-meng Gu, Shuai-shuai Liu, Yue Zhang, Jie Wang, Lu Tie et al. · 2023 · Biochemical Pharmacology
- Deregulation of CLTC interacts with TFG, facilitating osteosarcoma via the TGF‐beta and AKT/mTOR signaling pathwaysShi-jie Li, Pan Zhen, Kang Qin, Hua Guo, Yang Qingcheng, Cheng Dongdong · 2021 · Clinical and Translational Medicine
- Molecular Signaling Pathways as Potential Therapeutic Targets in OsteosarcomaParisa Maleki Dana, Fatemeh Sadoughi, Zatollah Asemi, Bahman Yousefi · 2022 · Current Medicinal Chemistry
- Comprehensive Analysis Identifies PI3K/Akt Pathway Alternations as an Immune-Related Prognostic Biomarker in Colon Adenocarcinoma Patients Receiving Immune Checkpoint Inhibitor TreatmentAnqi Lin, Tianqi Gu, Xigang Hu, Jian Zhang, Peng Luo · 2022 · Journal of Immunology Research
- WTAP promotes proliferation of esophageal squamous cell carcinoma via m 6 A‐dependent epigenetic promoting of PTP4A1Jiang Zou, Qiang Ma, Chuanli Gao, Miyuan Yang, Jilin Wen, Lei Xu, Xiaolan Guo, Xiaowu Zhong, Yixiang Duan · 2024 · Cancer Science
- miR-338-3p inhibits cell growth, invasion, and EMT process in neuroblastoma through targeting MMP-2Haibin Yuan, Fengli Liu, Tongsheng Ma, Zhandong Zeng, Ning Zhang · 2021 · Open Life Sciences
- PIK3CA mutation affects the proliferation of colorectal cancer cells through the PI3K-MEK/PDK1-GPT2 pathwayWenli Chen, Guangli Dai, Yike Qian, Wen Lian, Xueqing He, Hui Liu, Yunxing Gao, Xingli Tang, Bohan Dong · 2021 · Oncology Reports
- Intestinal Macrophage Autophagy and its Pharmacological Application in Inflammatory Bowel DiseaseZheng Yang, Yang Yu, Xu-Feng Chen, Sheng-Lan Yang, Xiaolong Tang, Zheng-Guo Xiang · 2021 · Frontiers in Pharmacology
- Targeting Signaling Pathway by Curcumin in OsteosarcomaZatollah Asemi, Bahman Yousefi, Parnia Rahnamay Farnood, Romina Danesh Pazhooh · 2022 · Current Molecular Pharmacology
- Mubritinib enhanced the inhibiting function of cisplatin in lung cancer by interfering with mitochondrial functionJingyao Dong, Dongshan Zhu, Mengmeng Chen, Taiwei Wang, Yan Gao, Wei Liu · 2022 · Thoracic Cancer
- DEPDC1B collaborates with GABRD to regulate ESCC progressionYunfeng Yuan, Ping Wei, Ruijie Zhang, Zhipeng Hao, Ni Zhang · 2022 · Cancer Cell International
- The distinct clinicopathological and prognostic implications of PIK3CA mutations in breast cancer patients from Central ChinaHaibo Wu, Wei Wang, Jun Du, Hong Li, Huogang Wang, Liangliang Huang, Hang Xiang, Jing Xie, Xiaoli Liu, Heng Li et al. · 2019 · Cancer Management and Research
- TMC5 is Highly Expressed in Human Cancers and Corelates to Prognosis and Immune Cell Infiltration: A Comprehensive Bioinformatics AnalysisHui Zhang, Xu Zhang, Weiguo Xu, Jian Wang · 2022 · Frontiers in Molecular Biosciences
- The Functional Mechanism of MicroRNA in Oral Lichen PlanusYunshan Li, Yaodong He, Junwei Xiang, Linfei Feng, Yuanyin Wang, Ran Chen · 2022 · Journal of Inflammation Research
- HIF‐1α mediates CXCR4 transcription to activate the AKT/mTOR signaling pathway and augment the viability and migration of activated B cell‐like diffuse large B‐cell lymphoma cellsZhen Jin, Rufang Xiang, Jian-Min Dai, Yefei Wang, Zizhen Xu · 2023 · Molecular Carcinogenesis
- Effect of STK3 on proliferation and apoptosis of pancreatic cancer cells via PI3K/AKT/mTOR pathwayJun Chen, Fuqiang Liu, Jiao Wu, Yichun Yang, Jin Hua He, Fan Wu, Kun Yang, Junfeng Li, Zhongxiang Jiang, Zheng Jiang · 2023 · Cellular Signalling
- SQLE Knockdown inhibits bladder cancer progression by regulating the PTEN/AKT/GSK3β signaling pathway through P53Fan Zou, Chen Wu, Tianbao Song, Xing Ji, Yunlong Zhang, Kang Chen, Weimin Hu, Linzhi Li, Jinzhuo Ning, Chenglong Li et al. · 2023 · Cancer Cell International
- 6-Gingerol protects cardiomyocytes against hypoxia-induced injury by regulating the KCNQ1OT1/miR-340-5p/PI3K/AKT pathwayFan PAN, Xiaopeng XU, Zhi ZHAN, Qunfeng XU · 2021 · Panminerva Medica
- TSC2 Mutations Were Associated with the Early Recurrence of Patients with HCC Underwent HepatectomyK. Song, Fu He, Yang Xin, Ge Guan, Junyu Huo, Qingwei Zhu, Ning Fan, Yuan Guo, Yun-jin Zang, Li-Qun Wu · 2021 · Pharmacogenomics and Personalized Medicine
- The Role of Paxillin Aberrant Expression in Cancer and Its Potential as a Target for Cancer TherapyWeixian Liu, Xinxian Huang, Weizhao Luo, Xinguang Liu, Wei‐Chun Chen · 2023 · International Journal of Molecular Sciences
- PI3K/AKT signaling in parasites and parasite diseases: Role and therapeutic potentialLujun Yan, Yating Li, Xing Yang, Rui Qiang Li, Chunyin Zhu, Xuedong He, Xiaoliang Jin, Guanghui Zheng, Naunain Mehmood, William Chi Shing Cho et al. · 2025 · Virulence
- Nigrosporins B, a Potential Anti-Cervical Cancer Agent, Induces Apoptosis and Protective Autophagy in Human Cervical Cancer Ca Ski Cells Mediated by PI3K/AKT/mTOR Signaling PathwayJing Zhang, Zhiyong Guo, Chang‐Lun Shao, Xueqing Zhang, Fan Cheng, Kun Zou, Jianfeng Chen · 2022 · Molecules
- MiR-18a-5p attenuates HER2-positive breast cancer development by regulating PI3K/AKT pathwayYongjun Liu, Yang Hua · 2023 · Cancer Biology & Therapy
- Unraveling DDIT4 in the VDR-mTOR pathway: a novel target for drug discovery in diabetic kidney diseaseHaitao Lu, Yuanyuan Jiao, Tianyu Yu, Jing-xuan Shi, Jingwei Tian, Guming Zou, Lin Liu, Li Zhuo · 2024 · Frontiers in Pharmacology
- The cancer-testis antigen a-kinase anchor protein 3 facilitates breast cancer progression via activation of the PTEN/PI3K/AKT/mTOR signalingChuan-Hua Zhan, Dong-Shen Ding, Wei jin Zhang, Hongliang Wang, Zhe-Yu Mao, Guo-Jun Liu · 2022 · Bioengineered
- The tumor suppressor NDRG2 cooperates with an mTORC1 inhibitor to suppress the Warburg effect in renal cell carcinomaXian Li, Guangdong Hou, Zheng Gang Zhu, Fei Yan, Fuli Wang, Di Wei, Yu Zheng, Jiarui Yuan, Wanxiang Zheng, Geng Zhang et al. · 2019 · Investigational New Drugs
- Targeting Cullin-RING Ubiquitin Ligases and the Applications in PROTACsLongyuan Gong, Danrui Cui, Xiufang Xiong, Yongchao Zhao · 2020 · Advances in experimental medicine and biology
- UBE2J1 knockdown promotes cell apoptosis in endometrial cancer via regulating PI3K/AKT and MDM2/p53 signalingPing Zhang, Huiping Guo, Fang Zhao, Ke Jia, Fei Yang, Xiaoli Liu · 2023 · Open Medicine
- Involvement of CaMKII in regulating the release of diplotene-arrested mouse oocytes by pAkt1 (Ser473)Lingling Liu, Hanwen Li, Ben Labbe, Yang Wang, Shitao Mao, Yu Qing Cao, Mingjing Zhao, Shuo Liu, Hang Yu, Xin Deng · 2019 · Cell Cycle
- Glaucocalyxin a prevents hypoxia-induced epithelial-mesenchymal transition in human gastric cancer cells through the PI3K/Akt signaling pathwayXi-Han Zhou, Weijin Ma, Xiaohui Li, Jiali Xu · 2020 · Journal of Receptors and Signal Transduction
- USP35 is a Potential Immunosuppressive Factor in Skin Cutaneous MelanomaQian Zhang, Yuanjie Liu, Jie-pin Li, Shuhong Zeng, Hui Shen, Mei Han, Shun Guo, Shenlin Liu, Xi Zou · 2022 · Journal of Inflammation Research
- Chamomile Essential Oil: Chemical Constituents and Antitumor Activity in MDA‐MB‐231 Cells through PI3K/Akt/mTOR Signaling PathwayZhonghua An, Xuelin Feng, Mengjia Sun, Yifan Wang, Hongbo Wang, Yanling Gong · 2023 · Chemistry & Biodiversity
- Antinociceptive Effects of Shenling Baizhu through PI3K‐Akt‐mTOR Signaling Pathway in a Mouse Model of Bone Metastasis with Small‐Cell Lung CancerZhe Chuan Feng, Ziyi Feng, Jie Han, Weimin Cheng, Bo Su, Jian Mo, Xinjian Feng, Sitan Feng, GuoJian Chen, Peng Huang et al. · 2020 · Evidence-based Complementary and Alternative Medicine
- Circular RNAs and Bladder CancerZhonglin Cai, Hongjun Li · 2020 · OncoTargets and Therapy
- Identification of the active compounds and their mechanisms of medicinal and edible Shanzha based on network pharmacology and molecular dockingHuimin Pei, Shaokang Wu, Lijun Zheng, Hanxun Wang, Xiangrong Zhang · 2021 · Journal of Food Biochemistry
- Nucleoporin 37 promotes the cell proliferation, migration, and invasion of gastric cancer through activating the PI3K/AKT/mTOR signaling pathwayJishui Zhang, Wenhao Lv, Yagang Liu, Weihua Fu, Baosheng Chen, Qiutong Ma, Xin Gao, Xiuxia Cui · 2021 · In Vitro Cellular & Developmental Biology - Animal
- LncRNA NORAD promotes the progression of myocardial infarction by targeting the miR-22-3p/PTEN axisChunxia Li, Lihui Zhang, Xingpeng Bu, Guofang Chu, Xiaofang Zhao, Yaru Liu · 2022 · Acta Biochimica et Biophysica Sinica
- 6‐Gingerol induces browning of white adipose tissue to improve obesity through PI3K/AKT‐RPS6‐mediated thermogenesis pathwayYasmin Alhamoud, Junhao Wu, Muhammad Ijaz Ahmad, Fang Chen, Fengqin Feng, Jing Wang · 2023 · Food Frontiers
- Development and Clinical Applications of PI3K/AKT/mTOR Pathway Inhibitors as a Therapeutic Option for LeukemiasAnna Karolyna da Costa Machado, Caio Bezerra Machado, Flávia Melo Cunha de Pinho Pessoa, Igor Valentim Barreto, Renan Brito Gadelha, Deivide de Sousa Oliveira, Rodrigo Monteiro Ribeiro, Germison Silva Lopes, Manoel Odorico de Moraes, Maria Elisabete Amaral de Moraes et al. · 2024 · Cancer Diagnosis & Prognosis
- Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1 ‐mediated fatty acid synthesisLixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim · 2024 · Molecular Oncology
- Metabolic profiling of patient-derived organoids reveals nucleotide synthesis as a metabolic vulnerability in malignant rhabdoid tumorsMarjolein M G Kes, Francisco Morales-Rodriguez, Esther A. Zaal, Terezinha Maria de Souza, Natalie Proost, Marieke van de Ven, Marry M. van den Heuvel‐Eibrink, Jeroen W. A. Jansen, Celia R. Berkers, Jarno Drost · 2024 · Cell Reports Medicine
- Metabolic Regulation of Hypoxia-Inducible Factors in HypothalamusDan Du, Yugang Zhang, Canjun Zhu, Hong Chen, Jia Man Sun · 2021 · Frontiers in Endocrinology
- Marsdenia tenacissima Extract Induces Autophagy and Apoptosis of Hepatocellular Cells via MIF/mToR SignalingShuai Lin, Qianwen Sheng, Xiaobin Ma, Shanli Li, Peng Xu, Cong Dai, Meng Wang, Huafeng Kang, Zhijun Dai · 2022 · Evidence-based Complementary and Alternative Medicine
- KIF23 is a potential biomarker of diffuse large B cell lymphomaYuqi Gong, Lingna Zhou, Liya Ding, Jing Zhao, Zhe Wang, Guoping Ren, Jing Zhang, Zhengrong Mao, Ren Zhou · 2022 · Medicine
- Gou Qi Zi inhibits proliferation and induces apoptosis through the PI3K/AKT1 signaling pathway in non-small cell lung cancerLingling Zhang, Yanju Gong, Lei Zhang, Bing Liang, Huan Xu, Wangming Hu, Zhong Jin, Xiao jing Wu, Xiongbin Chen, Min Li et al. · 2022 · Frontiers in Oncology
- Dihydroartemisinin inhibits the activation and proliferation of hepatic stellate cells by regulating miR‑29b‑3pSheng Huan, Sumin Sun, Shilian Song, Jin Dai, Guining Zhu, Yanling Zhong, Yihao Ji, Shizhong Zheng, Guoping Yin · 2023 · International Journal of Molecular Medicine
- Deltonin enhances gastric carcinoma cell apoptosis and chemosensitivity to cisplatin via inhibiting PI3K/AKT/mTOR and MAPK signalingLin Yang, Ya-Nan Liu, Yi Gu, Qi Guo · 2023 · World Journal of Gastrointestinal Oncology
- MicroRNA miR-23b-3p promotes osteosarcoma by targeting ventricular zone expressed PH domain-containing 1 (VEPH1)/phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) pathwayLiang Fan, Xing Cao, Yanrong Lei · 2021 · Bioengineered
- The Involvement of WDHD1 in the Occurrence of Esophageal Cancer as a Downstream Target of PI3K/AKT PathwayQingying Xian, Danxia Zhu · 2022 · Journal of Oncology
- Bioinformatics and validation reveal the potential target of curcumin in the treatment of diabetic peripheral neuropathyZiqiang Lin, Suo Wang, Yu Cao, Jialing Lin, Ailing Sun, Wei Huang, Jun Zhou, Qingxiong Hong · 2024 · Neuropharmacology
- Effects of natural source polysaccharides on neurological diseases: A reviewLuyuan Yang, Hailu Hou, Liping Lu, Yu Huining Sun, Ruhai Chen, Qingfang Deng, Huaguo Chen · 2025 · International Journal of Biological Macromolecules
- Abrogation of histone deacetylases (HDACs) decreases survival of chronic myeloid leukemia cells: New insight into attenuating effects of the PI3K/c‐Myc axis on panobinostat cytotoxicitySara Zehtabcheh, Amir‐Mohammad Yousefi, Sina Salari, Majid Safa, Majid Momeny, Seyed Hamidollah Ghaffari, Davood Bashash · 2021 · Cell Biology International
- A pharmacognostic approach for mitigating pancreatic cancer: emphasis on herbal extracts and phytoconstituentsShruti Gupta, Atul Kumar, Kiran Kumar Tejavath · 2021 · Future Journal of Pharmaceutical Sciences
- AHNAK2 Promotes the Progression of Differentiated Thyroid Cancer through PI3K/AKT Signaling PathwayMin Xu, Jialiang Wen, Qiding Xu, Huihui Li, Bangyi Lin, Adheesh Bhandari, Jinmiao Qu · 2022 · Current Cancer Drug Targets
- CircMAN1A2 promotes vasculogenic mimicry of nasopharyngeal carcinoma cells through upregulating ERBB2 via sponging miR-940Huaqing Mo, JINGYI SHEN, YUXIAO ZHONG, ZENAN CHEN, Tong Wu, YANYU LV, YANYAN XIE, YANRONG HAO · 2022 · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
- Cell adhesion molecule 4 suppresses cell growth and metastasis by inhibiting the Akt signaling pathway in non-small cell lung cancerFang Luo, Yi Zhao, Jiwei Liu · 2020 · The International Journal of Biochemistry & Cell Biology